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https://www.readbyqxmd.com/read/29330835/international-guidelines-for-groin-hernia-management
#1
(no author information available yet)
INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize complications, and improve results. The main goal of these guidelines is to improve patient outcomes, specifically to decrease recurrence rates and reduce chronic pain, the most frequent problems following groin hernia repair. They have been endorsed by all five continental hernia societies, the International Endo Hernia Society and the European Association for Endoscopic Surgery...
January 12, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29303288/-the-complications-after-lung-transplantation
#2
Petr Jakubec, Monika Žurková, Lenka Hajdová, Aneta Křenková, Vítězslav Kolek
Lung transplantation (LuTx) is an important treatment for a selected group of patients in the terminal stage of a number of lung diseases, which can bring them a significant improvement in quality of life and long-term survival. Nowadays a perioperative period is not significant limitation for patient survival due to the development of transplant surgery, but the period of months to years after LuTx is crucial for survival. The post-transplant period is very complicated for LuTx patients due to a special treatment regimen, special medication, especially immunosuppressive drugs and the possibility of many complications, whether early or late or acute or chronic...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29301541/compounded-medication-for-patients-with-rare-diseases
#3
REVIEW
Marc Dooms, Maria Carvalho
BACKGROUND: When there is no authorized on- or in absence even no off-label treatment for patients with rare diseases, pharmacists have to compound medicinal products to meet the patients special needs. However it is important that there is evidence in the medical and/or pharmaceutical literature for such compounded medications. POSITION STATEMENT: Pharmaceutical compounding must be performed in the best possible circumstances by certified practitioners (pharmacists) using validated standard operating procedures (standardized formulations) in order to obtain medicinal products of the highest quality to assure patient safety...
January 4, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29275300/three-dimensional-printing-based-reconstruction-of-a-maxillary-bone-defect-in-a-dog-following-tumor-removal
#4
Se Eun Kim, Kyung Mi Shim, Kwangsik Jang, Jin-Hyung Shim, Seong Soo Kang
Three-dimensional (3D) printing has been applied extensively not only in human, but also veterinary medicine. However, the technique is still used in the clinical area for a surgical plan or education prior to surgery. Thus, we report a case of reconstruction after tumor removal surgery with the use of a 3D-printed scaffold. A 12-year-old female mixed dog had a left caudal maxillary mass. Based on computed tomography images, a defect was confirmed on the maxillary bone due to the oral mass, and a surgical plan was designed to remove the oral mass and graft the 3D printed scaffold...
January 2018: In Vivo
https://www.readbyqxmd.com/read/29260394/validation-and-evaluation-of-measuring-methods-for-the-3d-documentation-of-external-injuries-in-the-field-of-forensic-medicine
#5
Ursula Buck, Kirsten Buße, Lorenzo Campana, Christian Schyma
Three-dimensional (3D) measurement techniques are gaining importance in many areas. The latest developments brought more cost-effective, user-friendly, and faster technologies onto the market. Which 3D techniques are suitable in the field of forensic medicine and what are their advantages and disadvantages? This wide-ranging study evaluated and validated various 3D measurement techniques for the forensic requirements. High-tech methods as well as low-budget systems have been tested and compared in terms of accuracy, ease of use, expenditure of time, mobility, cost, necessary knowhow, and their limitations...
December 19, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29214621/sandfly-fever-in-afghanistan-a-sometimes-overlooked-disease-of-military-importance-a-case-series-and-review-of-the-literature
#6
John W Downs, Daniel T Flood, Nicholas H Orr, Jason A Constantineau, James W Caviness
Sandfly fever, sometimes known as pappataci fever or Phlebotomus fever, is a vector transmitted viral illness with a history of affecting naïve military formations that travel through or fight in areas in which the infection is endemic. We present a series of 4 hospitalized cases of sandfly fever (2 presumptive, 2 laboratory confirmed) that were admitted to a Role 3 hospital in Afghanistan for evaluation and treatment following medical evacuation from a forward area for marked fevers and malaise. Laboratory evaluation of these cases was significant for leukopenia and thrombocytopenia, consistent with historical descriptions of sandfly fever...
October 2017: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/29209959/improving-the-level-and-quality-of-ethics-review-in-chinese-medicine-and-integrative-medicine
#7
Cheng-Bin Zhang, En-Chang Li
Three features of ethics review in Chinese medicine (CM) and integrative medicine (IM) were put forward in this paper. It is consistent with the principles of ethical review in Western medicine; it has to be compliant with the laws of CM and IM; emphasis should be laid on the review of clinical practice facts and experience. Three problems were pointed out. The characteristics of CM and IM are not distinctive enough, operation procedures need to be refined and effectiveness remains to be improved. Based on the mentioned above, seven measures were proposed to improve the level and quality of ethics review in CM and IM, including better brand awareness, considerable tolerance, treatment based on disease differentiation and syndrome differentiation, scientific review and toxicity and side effects of CM, perfection of the ethics review system, reasonable procedures of ethics review and more specialized ethics review workers...
December 5, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29197663/prediction-of-potential-drivers-connecting-different-dysfunctional-levels-in-lung-adenocarcinoma-via-a-protein-protein-interaction-network
#8
Fei Yuan, WenCong Lu
Lung cancer is a serious disease that threatens an affected individual's life. Its pathogenesis has not yet to be fully described, thereby impeding the development of effective treatments and preventive measures. "Cancer driver" theory considers that tumor initiation can be associated with a number of specific mutations in genes called cancer driver genes. Four omics levels, namely, (1) methylation, (2) microRNA, (3) mutation, and (4) mRNA levels, are utilized to cluster cancer driver genes. In this study, the known dysfunctional genes of these four levels were used to identify novel driver genes of lung adenocarcinoma, a subtype of lung cancer...
November 29, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29186497/for-as-long-as-necessary-examining-30-years-of-merck-co-inc-s-focus-on-achieving-elimination-of-onchocerciasis-and-lymphatic-filariasis
#9
Kenneth M Gustavsen, Brenda D Colatrella, Theresa McCoy
Established by Merck & Co., Inc. (known as MSD outside of the United States and Canada) in 1987, the Mectizan Donation Program (MDP) is the longest running disease-specific program of its kind. Initially aimed at control of onchocerciasis (river blindness), the company expanded its commitment through the MDP in 1998 to include lymphatic filariasis (LF). Both diseases are now candidates for elimination and the company is engaged in several global partnerships to help advance towards that goal. To support the steadily growing demand from country-led disease elimination programs, the company has put in place several administrative and operational improvements...
November 23, 2017: International Health
https://www.readbyqxmd.com/read/29161391/an-overview-of-space-medicine
#10
P D Hodkinson, R A Anderton, B N Posselt, K J Fong
Space medicine is fundamental to the human exploration of space. It supports survival, function and performance in this challenging and potentially lethal environment. It is international, intercultural and interdisciplinary, operating at the boundaries of exploration, science, technology and medicine. Space medicine is also the latest UK specialty to be recognized by the Royal College of Physicians in the UK and the General Medical Council. This review introduces the field of space medicine and describes the different types of spaceflight, environmental challenges, associated medical and physiological effects, and operational medical considerations...
December 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29152907/hierarchical-multicomponent-inorganic-metamaterials-intrinsically-driven-self-assembly-at-the-nanoscale
#11
REVIEW
Igor Levchenko, Kateryna Bazaka, Michael Keidar, Shuyan Xu, Jinghua Fang
Increasingly intricate in their composition and structural organization, hierarchical multicomponent metamaterials with nonlinear spatially reconfigurable functionalities challenge the intrinsic constraints of natural materials, revealing tremendous potential for the advancement of biochemistry, nanophotonics, and medicine. Recent breakthroughs in high-resolution nanofabrication utilizing ultranarrow, precisely controlled ion or laser beams have enabled assembly of architectures of unprecedented structural and functional complexity, yet costly, time- and energy-consuming high-resolution sequential techniques do not operate effectively at industry-required scale...
November 20, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29142543/career-choices-of-medical-doctors-at-graduate-level-a-multicenter-study
#12
Sadaf Zia, Maisam Abbas, Mehreen Sulaiman, Salman Matiullah Sheikh
Objective: To find out the specialty choices being taken by Final year Medical students and graduate Doctors. Method: This is a cross sectional survey study which was conducted over two months from 1(st) November to 31(st) December 2016. Final year students and house job doctors were asked for the filling of Performa, after filling the consent form. A self-developed, anonymous questionnaire was used to conduct the study using close ended type of questions. This was a multi-center study conducted at Dow International Medical College and Jinnah Medical and Dental College...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29116361/intermediate-care-units-recommendations-on-facilities-and-structure
#13
REVIEW
C Waydhas, E Herting, S Kluge, A Markewitz, G Marx, E Muhl, T Nicolai, K Notz, V Parvu, M Quintel, E Rickels, D Schneider, K R Steinmeyer-Bauer, G Sybrecht, T Welte
A growing number of patients with increasingly complex or specialized diseases are being treated in hospitals worldwide. The treatment requirements of some of these patients are exceeding the capacity of standard nursing units. However, the severity of these diseases or the treatment requirements for these specific clinical pictures do not always justify admission to an intensive care unit. For this reason, an increasing number of special units (intermediate care units) are being set up to offer highly specialized treatment and close monitoring, in order to fulfil an intermediate role between the standard care unit and the intensive care unit...
November 7, 2017: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/29080876/-a-cryobank-as-an-attribute-of-omics-technologies
#14
A A Sazanov, Kh Kh Erganokov, E Pfeifer
Biobanks are systematic and annotated collections of biological samples based on the system of standard operating procedures (SOP) and corresponding to the recommendations of the International Society for Biological and Environmental Repositories (ISBER). Standardization of conditions of obtaining, processing, storage of samples and providing to an end user are crucial in the activities of the biobank. The attributes of biobanks include common principles of labeling and annotation of biological samples using specialized software, an automated monitoring system of storage conditions, and registration of biosamples...
October 2017: Biomedit︠s︡inskai︠a︡ Khimii︠a︡
https://www.readbyqxmd.com/read/29061762/descriptive-analysis-of-the-medical-care-performed-in-the-spanish-military-role-1-medical-treatment-facility-deployed-in-operation-inherent-resolve-iraq-2015-2016
#15
Rafael García Cañas, R Navarro Suay
INTRODUCTION: Operation 'Inherent Resolve' was approved by the United Nations in August 2014 with the objective of suppressing the Islamic State in Iraq and the Levant and increasing the region's stability. The mission of the Spanish military forces within this was to direct training missions for the Iraqi Army. The aim of this study is to analyse the medical care provided in the Spanish Role 1 deployed medical treatment facility during Operation 'Apoyo a Irak'. METHODS: A cross-sectional, descriptive and retrospective study was conducted between 15 December 2015 and 18 November 2016...
October 23, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29049875/a-protocol-for-the-direct-conversion-of-lactones-to-lactams-mediated-by-1-5-7-triazabicyclo-4-4-0-dec-5-ene-synthesis-of-pyridopyrazine-1-6-diones
#16
Danica A Rankic, Cory M Stiff, Christopher W Am Ende, John M Humphrey
We present an operationally simple lactone-to-lactam transformation utilizing diverse amine nucleophiles. The key steps of amidation, alcohol activation and cyclization are all mediated by one reagent (TBD) in a single vessel at room temperature. We illustrate the convenience of this protocol by synthesizing a wide range of N-alkyl, N-aryl and N-hetereoaryl pyridopyrazine-1,6-diones, an important class of medicinally significant lactams. Furthermore, the reported methodology can be applied to the synthesis of milligram to hundred gram quantities of pyridopyrazine-1,6-diones without the use of specialized equipment...
October 19, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29040454/to-fly-as-a-pilot-after-cardiac-surgery
#17
Thomas Syburra, Ed Nicol, Stuart Mitchell, Denis Bron, Ulrich Rosendahl, John Pepper
Aircrew are responsible for safe and reliable aircraft operations. Cardiovascular disease accounts for 50% of all pilot licences declined or withdrawn for medical reasons in Western Europe and is the most common cases of sudden incapacitation in flight. Aircrew retirement age is increasing (up to age 65) in a growing number of airlines and the burden of subclinical, but potentially significant, coronary atherosclerosis is unknown in qualified pilots above age 40. Safety considerations are paramount in aviation medicine, and the most dreaded cardiovascular complications are thromboembolic events and rhythm disturbances due to their potential for sudden incapacitation...
October 13, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29037175/a-ten-year-study-of-midwife-led-care-at-an-austrian-tertiary-care-center-a-retrospective-analysis-with-special-consideration-of-perineal-trauma
#18
Barbara Bodner-Adler, Oliver Kimberger, Julia Griebaum, Peter Husslein, Klaus Bodner
BACKGROUND: In contrast to other countries, Austria rarely offers alternative models to medical led-care. In an attempt to improve the facilities, a midwife-led care service was incorporated within the Department of Obstetrics and Fetomaternal Medicine. The aim of the present study was to analyze the maternal and neonatal outcomes of this approach. METHODS: Over a 10-years period, a total of 2123 low-risk women receiving midwife-led care were studied. Among these women, 148 required obstetric referral...
October 16, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29026358/medicine-in-society-health-project-five-students-journey-to-a-resource-limited-clinic-in-the-haitian-countryside
#19
Aneesh Gupta, Marie Claire Lamb, John Sisney, Chantel Taylor, Timothy Ziethen, Yvens Laborde
BACKGROUND: Five medical students traveled with 4 doctors and a medical photographer to Mayaya, La Victoire, Haiti, as part of a Medicine in Society rotation to provide medical care to the indigenous population. METHODS: Preparation for the trip involved special study in identifying microbes and using blood analysis equipment; work in a clinic for underserved people in the New Orleans, LA, area; background reading; Haitian dialect classes; and development of ideas for streamlining clinic operations...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29018631/multi-parameter-ensemble-learning-for-automated-vertebral-body-segmentation-in-heterogeneously-acquired-clinical-mr-images
#20
Bilwaj Gaonkar, Yihao Xia, Diane S Villaroman, Allison Ko, Mark Attiah, Joel S Beckett, Luke Macyszyn
The development of quantitative imaging biomarkers in medicine requires automatic delineation of relevant anatomical structures using available imaging data. However, this task is complicated in clinical medicine due to the variation in scanning parameters and protocols, even within a single medical center. Existing literature on automatic image segmentation using MR data is based on the analysis of highly homogenous images obtained using a fixed set of pulse sequence parameters (TR/TE). Unfortunately, algorithms that operate on fixed scanning parameters do not avail themselves to real-world daily clinical use due to the existing variation in scanning parameters and protocols...
2017: IEEE Journal of Translational Engineering in Health and Medicine
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