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https://www.readbyqxmd.com/read/28484301/comparative-analysis-of-family-medicine-education-and-exams-at-cathedras-of-family-medicine-of-universities-in-southeastern-europe-splitska-inicijativa-sarajevo-2017
#1
Izet Masic, Olivera Batic Mujanovic, Maja Racic, Larisa Gavran, Kosana Stanetic, Merzika Hodzic, Milena Cojic, Ljiljana Cvejanov-Kezunovic, Aleksandar Stepanovic, Katarina Stavrikj, Zaim Jatic, Edita Cerny Obrdalj, Amra Zalihic, Ksenija Tusek-Bunc
Education means: learning, teaching or the process of acquiring skills or behavior modification through various exercises. Traditionally, medical education meant the oral, practical and more passive transferring of knowledge and skills from the educators to students and health professionals. Today the importance of focus on educational quality, particularly in the professions operating in the services required by people is agreed by all involved. The higher educational system shoulders some critical responsibilities in the economic, social, cultural and educational development and growth in the communities...
March 2017: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28477077/immunophenotyping-as-a-new-tool-for-classification-and-monitoring-of-systemic-autoimmune-diseases
#2
Yves Renaudineau
The clinical course of systemic autoimmune diseases (SADs) varies greatly, even between individuals with the same disease. Understanding of the immune actors is informative and could lead to significant improvements in diagnosis, monitoring, initial treatment decisions and/or follow-up. However, immunological changes in mononuclear cells associated with SADs have been only partially described, and usually are limited to analysis of peripheral blood cells (less than 5% of the total mononuclear pool). Another limitation is technological, related to utilization of flow cytometry, which remains highly variable with regards to sample preparation, reagents, instrument constraints, and data analysis...
May 5, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28411354/preventing-the-complications-associated-with-the-use-of-dermal-fillers-in-facial-aesthetic-procedures-an-expert-group-consensus-report
#3
REVIEW
Fernando Urdiales-Gálvez, Nuria Escoda Delgado, Vitor Figueiredo, José V Lajo-Plaza, Mar Mira, Francisco Ortíz-Martí, Rosa Del Rio-Reyes, Nazaret Romero-Álvarez, Sofía Ruiz Del Cueto, María A Segurado, Cristina Villanueva Rebenaque
BACKGROUND: The use of dermal fillers in minimally invasive facial aesthetic procedures has become increasingly popular of late, yet as the indications and the number of procedures performed increase, the number of complications is also likely to increase. Paying special attention to specific patient characteristics and to the technique used can do much to avoid these complications. Indeed, a well-trained physician can also minimize the impact of such problems when they do occur. METHODS: A multidisciplinary group of experts in aesthetic treatments reviewed the main factors associated with the complications that arise when using dermal fillers...
April 14, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28389399/integrating-musculoskeletal-education-and-patient-care-at-medical%C3%A2-student-run-free-clinics
#4
Thomas McQuillan, Nate Wilcox-Fogel, Emily Kraus, Amy Ladd, Michael Fredericson
BACKGROUND: Student-run free clinics (SRFCs) have emerged as an important educational component of United States (US) medical schools. Despite the prevalence of musculoskeletal (MSK) problems presenting to SRFCs, students and clinics are often unprepared to diagnose and to treat common MSK complaints. OBJECTIVE: We sought to determine the scope of diagnosis and treatment at a medical student-run free clinic specializing in musculoskeletal care using physical medicine and rehabilitation (PM&R) residents...
April 5, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28382802/major-clinical-research-advances-in-gynecologic-cancer-in-2016-10-year-special-edition
#5
REVIEW
Dong Hoon Suh, Miseon Kim, Kidong Kim, Hak Jae Kim, Kyung Hun Lee, Jae Weon Kim
In 2016, 13 topics were selected as major research advances in gynecologic oncology. For ovarian cancer, study results supporting previous ones regarding surgical preventive strategies were reported. There were several targeted agents that showed comparable responses in phase III trials, including niraparib, cediranib, and nintedanib. On the contrary to our expectations, dose-dense weekly chemotherapy regimen failed to prove superior survival outcomes compared with conventional triweekly regimen. Single-agent non-platinum treatment to prolong platinum-free-interval in patients with recurrent, partially platinum-sensitive ovarian cancer did not improve and even worsened overall survival (OS)...
May 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28377010/the-quality-of-postoperative-pain-therapy-in-german-hospitals
#6
Winfried Meißner, Marcus Komann, Joachim Erlenwein, Ulrike Stamer, André Scherag
BACKGROUND: Many patients in German hospitals complain of inadequate treatment of their postoperative pain. Hospital-related structural and procedural variables may affect pain perception and patient satisfaction. We studied the association of individual variables with outcome quality. METHODS: Data from the years 2011 to 2014 from the world's largest acute pain registry (QUIPS) were evaluated. The analysis was performed with mixed linear regression models. RESULTS: We studied registry data from 138 German hospitals concerning four commonly performed types of operations (total number of operations, 21 114) and found that the intensity of pain, functional impairment, and satisfaction with postoperative pain therapy were all highly variable from one hospital to another...
March 10, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28353261/information-management
#7
Alberto Labarga, Izaskun Beloqui, Angel G Martin
The collection and storage of human tissue samples has been undertaken in medicine for centuries; however, biobanking has only recently become a dedicated activity. The technological developments that have allowed the procurement and long-term storage of viable human cells ex vivo, and to obtain relevant scientific information, including genetic information, provide tremendous possibilities for advancing biomedical research. At the same time, these possibilities have raised complex information management issues regarding samples, processing, donor information, traceability, and use of the sample...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28350278/stroke-doctors-who-are-we-a-world-stroke-organization-survey
#8
Atte Meretoja, Monica Acciarresi, Rufus O Akinyemi, Bruce Campbell, Dar Dowlatshahi, Coralie English, Nils Henninger, Alexandre Poppe, Jukka Putaala, Monica Saini, Shoichiro Sato, Bo Wu, Michael Brainin, Bo Norrving, Stephen Davis
Background Specialist training provides skilled workforce for service delivery. Stroke medicine has evolved rapidly in the past years. No prior information exists on background or training of stroke doctors globally. Aims To describe the specialties that represent stroke doctors, their training requirements, and the scientific organizations ensuring continuous medical education. Methods The World Stroke Organization conducted an expert survey between June and November 2014 using e-mailed questionnaires. All Organization for Economic Co-operation and Development countries with >1 million population and other countries with >50 million population were included ( n = 49, total 5...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28346408/gut-microbial-metabolites-limit-the-frequency-of-autoimmune-t-cells-and-protect-against-type-1-diabetes
#9
Eliana Mariño, James L Richards, Keiran H McLeod, Dragana Stanley, Yu Anne Yap, Jacinta Knight, Craig McKenzie, Jan Kranich, Ana Carolina Oliveira, Fernando J Rossello, Balasubramanian Krishnamurthy, Christian M Nefzger, Laurence Macia, Alison Thorburn, Alan G Baxter, Grant Morahan, Lee H Wong, Jose M Polo, Robert J Moore, Trevor J Lockett, Julie M Clarke, David L Topping, Leonard C Harrison, Charles R Mackay
Gut dysbiosis might underlie the pathogenesis of type 1 diabetes. In mice of the non-obese diabetic (NOD) strain, we found that key features of disease correlated inversely with blood and fecal concentrations of the microbial metabolites acetate and butyrate. We therefore fed NOD mice specialized diets designed to release large amounts of acetate or butyrate after bacterial fermentation in the colon. Each diet provided a high degree of protection from diabetes, even when administered after breakdown of immunotolerance...
May 2017: Nature Immunology
https://www.readbyqxmd.com/read/28343420/portable-devices-and-mobile-instruments-for-infectious-diseases-point-of-care-testing
#10
Luc Bissonnette, Michel G Bergeron
Rapidity, simplicity, and portability are highly desirable characteristics of tests and devices designed for performing diagnostics at the point of care (POC), either near patients managed in healthcare facilities or to offer bioanalytical alternatives in external settings. By reducing the turnaround time of the diagnostic cycle, POC diagnostics can reduce the dissemination, morbidity, and mortality of infectious diseases and provide tools to control the global threat of antimicrobial resistance. Areas covered: A literature search of PubMed and Google Scholar, and extensive mining of specialized publications, Internet resources, and manufacturers' websites have been used to organize and write this overview of the challenges and requirements associated with the development of portable sample-to-answer diagnostics, and showcase relevant examples of handheld devices, portable instruments, and less mobile systems which may or could be operated at POC...
April 11, 2017: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/28290940/effects-of-combat-deployment-on-anthropometrics-and-physiological-status-of-u-s-army-special-operations-forces-soldiers
#11
Emily K Farina, Jonathan C Taylor, Gary E Means, Kelly W Williams, Nancy E Murphy, Lee M Margolis, Stefan M Pasiakos, Harris R Lieberman, James P McClung
INTRODUCTION: U.S. Army Special Operations Forces (SOF) soldiers deploy frequently and conduct military operations through special warfare and surgical strike capabilities. Tasks required to execute these capabilities may induce physical and mental stress and have the potential to degrade soldier physiological status. No investigations have longitudinally characterized whether combat deployment alters anthropometrics or biochemical markers of physiological status in a SOF population of frequent deployers...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28285485/human-performance-optimization-and-precision-performance-the-future-of-special-operations-human-performance-efforts
#12
Adam Russell, Patricia A Deuster
The Precision Medicine Initiative (PMI) was launched by the White House to promote individualized medicine. Although the focus of the PMI is on curing disease, we introduce the concept of Precision Performance (P2)- advances that might "enable a new era of human performance optimization through research, technology, and policies that empower warfighters and those who support them to work together toward development of individually optimized performance" (The White House, 2015). We provide a limited review of the current state of the science in human performance optimization (HPO) and show that averages among individuals can be both misleading and potentially counterproductive...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28284483/tactical-combat-casualty-care-beginnings
#13
REVIEW
Frank K Butler
Tactical Combat Casualty Care (TCCC) is a set of evidence-based, best-practice prehospital trauma care guidelines customized for use on the battlefield. The origins of TCCC were nontraditional. The TCCC program began as a Naval Special Warfare biomedical research effort launched after the realization that extremity hemorrhage, a leading cause of preventable death on the battlefield, was not being treated with a readily available and highly effective intervention: the tourniquet. This insight prompted a systematic reevaluation of all aspects of battlefield trauma care that was conducted from 1993 to 1996 as a joint effort by special operations medical personnel and the Uniformed Services University of the Health Sciences...
March 8, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28279652/the-transition-to-the-committee-on-tactical-combat-casualty-care
#14
REVIEW
Stephen D Giebner
The original Tactical Combat Casualty Care (TCCC) guidelines were published in a special supplement to Military Medicine in 1996 as the terminal deliverable of a 2-year development project funded by the United States Special Operations Command (USSOCOM). Two years later, the USSOCOM Biomedical Initiatives Steering Committee (BISC) promulgated its Task Statement 5-98, in which it called for the formation of a panel of subject matter experts to update the TCCC guidelines. This article discusses the formation of the Committee on Tactical Combat Casualty Care (CoTCCC) and the changes to the original guidelines that constituted the first update...
March 6, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28274726/a-population-genetics-perspective-on-the-determinants-of-intra-tumor-heterogeneity
#15
Zheng Hu, Ruping Sun, Christina Curtis
Cancer results from the acquisition of somatic alterations in a microevolutionary process that typically occurs over many years, much of which is occult. Understanding the evolutionary dynamics that are operative at different stages of progression in individual tumors might inform the earlier detection, diagnosis, and treatment of cancer. Although these processes cannot be directly observed, the resultant spatiotemporal patterns of genetic variation amongst tumor cells encode their evolutionary histories. Such intra-tumor heterogeneity is pervasive not only at the genomic level, but also at the transcriptomic, phenotypic, and cellular levels...
March 5, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28257636/endothelial-and-smooth-muscle-cells-derived-from-human-cardiac-explants-demonstrate-angiogenic-potential-and-suitable-for-design-of-cell-containing-vascular-grafts
#16
I S Zakharova, M K Zhiven', Sh B Saaya, A I Shevchenko, A M Smirnova, A Strunov, A A Karpenko, E A Pokushalov, L N Ivanova, P I Makarevich, Y V Parfyonova, E Aboian, S M Zakian
BACKGROUND: Endothelial and smooth muscle cells are considered promising resources for regenerative medicine and cell replacement therapy. It has been shown that both types of cells are heterogeneous depending on the type of vessels and organs in which they are located. Therefore, isolation of endothelial and smooth muscle cells from tissues relevant to the area of research is necessary for the adequate study of specific pathologies. However, sources of specialized human endothelial and smooth muscle cells are limited, and the search for new sources is still relevant...
March 3, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28157404/whole-slide-imaging-for-analytical-anatomic-pathology-and-telepathology-practical-applications-today-promises-and-perils
#17
Alton Brad Farris, Cynthia Cohen, Thomas E Rogers, Geoffrey H Smith
Whole slide imaging (WSI) offers a convenient, tractable platform for measuring features of routine and special-stain histology or in immunohistochemistry staining by using digital image analysis (IA). We now routinely use IA for quantitative and qualitative analysis of theranostic markers such as human epidermal growth factor 2 (HER2/neu), estrogen and progesterone receptors, and Ki-67. Quantitative IA requires extensive validation, however, and may not always be the best approach, with pancreatic neuroendocrine tumors being one example in which a semiautomated approach may be preferable for patient care...
April 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28114092/-utilization-of-technological-resources-within-the-framework-of-operation-of-a-mobile-mental-health-unit
#18
D Garoni, D Sarantidis, K Katsadoros
Telepsychiatry was introduced in the early 1950's for the provision of mental health services from a distance. In 1990 the progress made in telecommunications technologies caused a significant expansion in telepsychiatry services. It can refer to store and forward technologies, interactive technologies, remote monitoring technologies and it is applied to contribute to the lift of restrictions placed on providing mental health services. Restrictions may exist due to geographic isolation, lack of specialized services, high cost of moving patients etc...
October 2016: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/28113993/towards-pervasive-gait-analysis-for-medicine-with-wearable-sensors-a-systematic-review-for-clinicians-and-medical-researchers
#19
Shanshan Chen, John Lach, Benny Lo, Guang-Zhong Yang
After decades of evolution, measuring instruments for quantitative gait analysis have become an important clinical tool for assessing pathologies manifested by gait abnormalities. However, such instruments tend to be expensive and require expert operation and maintenance besides their high cost, thus limiting them to only a small number of specialized centers. Consequently, gait analysis in most clinics today still relies on observation-based assessment. Recent advances in wearable sensors, especially inertial body sensors, have opened up a promising future for gait analysis...
September 22, 2016: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28099985/-prospective-evaluation-of-the-quality-of-the-results-of-thyroid-surgery-in-an-ent-department
#20
Peter Rolf Issing, Hendrik Tebben, Martin Wenger, Torsten Köhler
Although the thyroid gland is located in the neck it is not a matter of fact that it is a clinical issue for the otorhinolaryngologist in Germany. Probably due to historic reasons general surgeons usually perform operations on the thyroid. As at our department this kind of treatment is an established procedure we prospectively evaluated our thyroid cases in order to present our results.The prospective study started in the year of 2014. So far 231 patients were enrolled with an average age of 53,5 years (16-89)...
April 2017: Laryngo- Rhino- Otologie
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