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advancement in parasitology

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https://www.readbyqxmd.com/read/28717322/th1-th2-balance-and-humoral-immune-response-to-potential-antigens-as-early-diagnostic-method-of-equine-strongylus-nematode-infection
#1
Faten A M Abo-Aziza, Seham H M Hendawy, Amira H El Namaky, Heba M Ashry
AIM: The aim of this study was to investigate the early diagnosis of strongyle infection based on early changes in Th1 and Th2 cytokines beside the diagnostic accuracy values and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and western blotting profiles using prepared strongyles antigens. MATERIALS AND METHODS: A total of 73 donkeys had a mean age of 4-32 years old were parasitologically examined for strongyle infection. The early changes in Th1 and Th2 cytokines were determined, and the diagnostic accuracy values and SDS-PAGE and western blotting profiles were performed using prepared strongyles antigens; crude somatic Strongylusvulgaris (CSS), excretory-secretory S...
June 2017: Veterinary World
https://www.readbyqxmd.com/read/28686693/ivermectin-treatment-of-loa-loa-hyper-microfilaraemic-baboons-papio-anubis-assessment-of-microfilarial-loads-haematological-and-biochemical-parameters-and-histopathological-changes-following-treatment
#2
Samuel Wanji, Ebanga-Echi J Eyong, Nicholas Tendongfor, Che J Ngwa, Elive N Esuka, Arnaud J Kengne-Ouafo, Fabrice R Datchoua-Poutcheu, Peter Enyong, Dalen Agnew, Rob R Eversole, Adrian Hopkins, Charles D Mackenzie
BACKGROUND: Individuals with high intensity of Loa loa are at risk of developing serious adverse events (SAEs) post treatment with ivermectin. These SAEs have remained unclear and a programmatic impediment to the advancement of community directed treatment with ivermectin. The pathogenesis of these SAEs following ivermectin has never been investigated experimentally. The Loa/baboon (Papio anubis) model can be used to investigate the pathogenesis of Loa-associated encephalopathy following ivermectin treatment in humans...
July 7, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28555175/maldi-tof-ms-profiling-advances-in-species-identification-of-pests-parasites-and-vectors
#3
REVIEW
Jayaseelan Murugaiyan, Uwe Roesler
Invertebrate pests and parasites of humans, animals, and plants continue to cause serious diseases and remain as a high treat to agricultural productivity and storage. The rapid and accurate species identification of the pests and parasites are needed for understanding epidemiology, monitoring outbreaks, and designing control measures. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) profiling has emerged as a rapid, cost effective, and high throughput technique of microbial species identification in modern diagnostic laboratories...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28456692/parasites-as-drivers-of-key-processes-in-aquatic-ecosystems-facts-and-future-directions
#4
B Sures, M Nachev, M Pahl, D Grabner, C Selbach
Despite the advances in our understanding of the ecological importance of parasites that we have made in recent years, we are still far away from having a complete picture of the ecological implications connected to parasitism. In the present paper we highlight key issues that illustrate (1) important contributions of parasites to biodiversity, (2) their integral role in ecosystems, (3) as well as their ecological effects as keystone species (4) and in biological invasion processes. By using selected examples from aquatic ecosystems we want to provide an insight and generate interest into the topic, and want to show directions for future research in the field of ecological parasitology...
April 26, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28424102/gaining-insights-into-the-ecological-role-of-the-new-zealand-sole-peltorhamphus-novaezeelandiae-through-parasites
#5
T Anglade, H S Randhawa
Despite the fact that tapeworms comprise the bulk of parasite communities of sharks in marine ecosystems, little is known about their life cycles and, more specifically, about the potential intermediate hosts they utilize as transmission routes. In the absence of morphological features required for specific identification of larval tapeworms from potential intermediate hosts, recent molecular advances have contributed to linking larval and adult parasites and, in some instances, uncovering unknown trophic links...
April 20, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28274280/a-novel-duplex-ddpcr-assay-for-the-diagnosis-of-schistosomiasis-japonica-proof-of-concept-in-an-experimental-mouse-model
#6
Kosala G Weerakoon, Catherine A Gordon, Pengfei Cai, Geoffrey N Gobert, Mary Duke, Gail M Williams, Donald P McManus
The current World Health Organization strategic plan targets the elimination of schistosomiasis as a public health problem by 2025 and accurate diagnostics will play a pivotal role in achieving this goal. DNA-based detection methods provide a viable alternative to some of the commonly used tests, notably microscopy and serology, for the diagnosis of schistosomiasis. The detection of parasite cell-free DNA in different clinical samples is a recent valuable advance, which provides significant benefits for accurate disease diagnosis...
March 9, 2017: Parasitology
https://www.readbyqxmd.com/read/28109302/review-of-mathematical-models-for-neglected-tropical-diseases-essential-tools-for-control-and-elimination-part-b-edited-by-maria-gloria-bas%C3%A3-%C3%A3-ez-and-roy-m-anderson
#7
REVIEW
Robert C Spear
Basáñez MG, Anderson RM, Editors: Mathematical Models for Neglected Tropical Diseases: Essential Tools for Control and Elimination, Part B, Volume 94, Advances in Parasitology, Academic Press; 2016, 430 pages. ISBN: 978-0-12-809971-1.
January 21, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/27822716/three-dimensional-cell-culture-models-for-investigating-human-viruses
#8
REVIEW
Bing He, Guomin Chen, Yi Zeng
Three-dimensional (3D) culture models are physiologically relevant, as they provide reproducible results, experimental flexibility and can be adapted for high-throughput experiments. Moreover, these models bridge the gap between traditional two-dimensional (2D) monolayer cultures and animal models. 3D culture systems have significantly advanced basic cell science and tissue engineering, especially in the fields of cell biology and physiology, stem cell research, regenerative medicine, cancer research, drug discovery, and gene and protein expression studies...
October 2016: Virologica Sinica
https://www.readbyqxmd.com/read/27815795/charles-william-lacaillade-biologist-parasitologist-educator-and-mentor
#9
Pascal James Imperato
Charles William Lacaillade (1904-1978) was an eminent biologist in the middle decades of the twentieth century. He was born in Lawrence, Massachusetts of parents whose ancestors were French Canadians. His father, also named Charles William Lacaillade, was a dentist who graduated from Tufts University School of Dentistry in 1898. His mother, Elodia Eno, came from a family of very successful businessmen. Lacaillade was the third of six children. His two older brothers, Harold Carleton and Hector Eno, both graduated from the University of Louisville, School of Dentistry, while his younger brother, Lawrence, became a businessman...
November 5, 2016: Journal of Community Health
https://www.readbyqxmd.com/read/27425574/trichinella-spiralis-adaptation-and-parasitism
#10
Dante Zarlenga, Zhengyuan Wang, Makedonka Mitreva
Publication of the genome from the clade I organism, Trichinella spiralis, has provided us an avenue to address more holistic problems in parasitology; namely the processes of adaptation and the evolution of parasitism. Parasitism among nematodes has evolved in multiple, independent events. Deciphering processes that drive species diversity and adaptation are keys to understanding parasitism and advancing control strategies. Studies have been put forth on morphological and physiological aspects of parasitism and adaptation in nematodes; however, data is now coming available to investigate adaptation, host switching and parasitism at the genomic level...
November 15, 2016: Veterinary Parasitology
https://www.readbyqxmd.com/read/27405532/advances-in-mapping-malaria-for-elimination-fine-resolution-modelling-of-plasmodium-falciparum-incidence
#11
Victor A Alegana, Peter M Atkinson, Christopher Lourenço, Nick W Ruktanonchai, Claudio Bosco, Elisabeth Zu Erbach-Schoenberg, Bradley Didier, Deepa Pindolia, Arnaud Le Menach, Stark Katokele, Petrina Uusiku, Andrew J Tatem
The long-term goal of the global effort to tackle malaria is national and regional elimination and eventually eradication. Fine scale multi-temporal mapping in low malaria transmission settings remains a challenge and the World Health Organisation propose use of surveillance in elimination settings. Here, we show how malaria incidence can be modelled at a fine spatial and temporal resolution from health facility data to help focus surveillance and control to population not attending health facilities. Using Namibia as a case study, we predicted the incidence of malaria, via a Bayesian spatio-temporal model, at a fine spatial resolution from parasitologically confirmed malaria cases and incorporated metrics on healthcare use as well as measures of uncertainty associated with incidence predictions...
July 13, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27387914/updates-on-feline-aelurostrongylosis-and-research-priorities-for-the-next-decade
#12
REVIEW
Hany M Elsheikha, Manuela Schnyder, Donato Traversa, Angela Di Cesare, Ian Wright, David W Lacher
Feline aelurostrongylosis, caused by the metastrongyloid nematode Aelurostrongylus abstrusus, is an important gastropod-borne parasitic lung disease in cats. Infection with A. abstrusus is widespread globally, but the increasing awareness of this parasite and the advent of more sensitive diagnostics have contributed to the apparent increase in its prevalence and geographic expansion. Clinical features may range in severity from subclinical to life-threatening respiratory disease. Parasitological standard techniques, such as visualization of the nematode first larval stage in faecal and respiratory (bronchial mucus or pleural fluid) samples, remain the mainstays of diagnosis...
July 7, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27351036/world-association-for-the-advancement-of-veterinary-parasitology-waavp-guideline-for-testing-the-efficacy-of-ectoparasiticides-for-fish
#13
C Sommerville, R Endris, T A Bell, K Ogawa, K Buchmann, D Sweeney
This guideline is intended to assist in the planning and execution of studies designed to assess the efficacy of ectoparasiticides for fish. It is the first ectoparasite-specific guideline to deal with studies set in the aquatic environment and therefore provides details for the maintenance of environmental standards for finfish. Information is included on a range of pre-clinical study designs as well as clinical studies in commercial/production sites, set within a regulatory framework. It provides information on the study animals, their welfare, husbandry and environmental requirements during the study...
March 30, 2016: Veterinary Parasitology
https://www.readbyqxmd.com/read/27131323/advances-in-genomics-of-entomopathogenic-fungi
#14
J B Wang, R J St Leger, C Wang
Fungi are the commonest pathogens of insects and crucial regulators of insect populations. The rapid advance of genome technologies has revolutionized our understanding of entomopathogenic fungi with multiple Metarhizium spp. sequenced, as well as Beauveria bassiana, Cordyceps militaris, and Ophiocordyceps sinensis among others. Phylogenomic analysis suggests that the ancestors of many of these fungi were plant endophytes or pathogens, with entomopathogenicity being an acquired characteristic. These fungi now occupy a wide range of habitats and hosts, and their genomes have provided a wealth of information on the evolution of virulence-related characteristics, as well as the protein families and genomic structure associated with ecological and econutritional heterogeneity, genome evolution, and host range diversification...
2016: Advances in Genetics
https://www.readbyqxmd.com/read/27088862/from-excessive-journal-self-cites-to-citation-stacking-analysis-of-journal-self-citation-kinetics-in-search-for-journals-which-boost-their-scientometric-indicators
#15
Petr Heneberg
Bibliometric indicators increasingly affect careers, funding, and reputation of individuals, their institutions and journals themselves. In contrast to author self-citations, little is known about kinetics of journal self-citations. Here we hypothesized that they may show a generalizable pattern within particular research fields or across multiple fields. We thus analyzed self-cites to 60 journals from three research fields (multidisciplinary sciences, parasitology, and information science). We also hypothesized that the kinetics of journal self-citations and citations received from other journals of the same publisher may differ from foreign citations...
2016: PloS One
https://www.readbyqxmd.com/read/27051192/anthelmintic-activity-of-indigofera-tinctoria-against-gastrointestinal-nematodes-of-sheep
#16
Ambalathaduvar Meenakshisundaram, Tirunelveli Jayagopal Harikrishnan, Thavasi Anna
AIM: Gastrointestinal (GI) nematodes are considered as a major constraint for successful sheep production. Control of these parasites heavily relies on the use of chemical anthelmintics. Over the past decades, the development of anthelmintic resistance to various groups of anthelmintics and problem of drug residues in animal products has awakened interest in medicinal plants as an alternative source of anthelmintics. Hence, this study was undertaken to evaluate the anthelmintic efficacy of Indigofera tinctoria by scientifically validated in vitro and in vivo tests approved by the World Association for the Advancement of Veterinary Parasitology...
January 2016: Veterinary World
https://www.readbyqxmd.com/read/26689179/serological-parasitological-and-molecular-tests-for-canine-visceral-leishmaniosis-diagnosis-in-a-longitudinal-study
#17
Cáris Maroni Nunes, Valéria Marçal Félix de Lima, Guilherme Dias de Melo, Henrique Borges de Paula, Maria Esther Gonçalves Pereira, Cristiana de Melo Trinconi Tronco, Roberto Mitsuyoshi Hiramoto, Marcia Dalastra Laurenti, Marcelo Nascimento Burattini
One of the measures to control visceral leishmaniosis (VL) in Brazil is the identification and culling of the canine reservoir. There is much controversy concerning this strategy, including the proper identification of positive dogs and the fact that the host-parasite relationship changes over time make it more challenging. A dynamic cohort of 62 dogs was followed every three months using serological and parasitological examinations and PCR. Positivity by PCR was higher than by serology and by parasitological examinations and showed a tendency to decrease over time, while serology tended to increase after six months...
October 2015: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/26583124/revisiting-the-posttherapeutic-cure-criterion-in-chagas-disease-time-for-new-methods-more-questions-doubts-and-polemics-or-time-to-change-old-concepts
#18
REVIEW
Marta de Lana, Olindo Assis Martins-Filho
One of the most relevant issues beyond the effectiveness of etiological treatment of Chagas disease is the lack of consensual/feasible tools to identify and certify the definitive parasitological cure. Several methods of distinct natures (parasitological, serological, and molecular) have been continuously proposed and novel perspectives are currently under investigation. Although the simultaneous use of distinct tests may offer better contributions and advances, it also leads to controversies of interpretation, with lack of mutual consent of cure criterion amongst researchers and physicians...
2015: BioMed Research International
https://www.readbyqxmd.com/read/26337266/efficacy-of-selected-anthelmintic-drugs-against-cyathostomins-in-horses-in-the-federal-state-of-brandenburg-germany
#19
Juliane K Fischer, Barbara Hinney, Matthew J Denwood, Donato Traversa, Georg von Samson-Himmelstjerna, Peter-Henning Clausen
Cyathostomins are currently the most common internal parasites of horses. With the intensive use of anthelmintic drugs over the past decades, resistance of cyathostomins to anthelmintics is becoming a growing problem in many countries. The aim of this study was to assess the current situation on horse farms in the German federal state of Brandenburg. A pre-selected population of horses from 24 premises that had shown a prevalence of cyathostomins higher than the average in a previous study was examined for anthelmintic efficacy...
December 2015: Parasitology Research
https://www.readbyqxmd.com/read/26154964/comparative-study-of-five-techniques-for-the-diagnosis-of-canine-gastrointestinal-parasites
#20
COMPARATIVE STUDY
Willian Marinho Dourado Coelho, Jancarlo Ferreira Gomes, Alexandre Xavier Falcão, Bianca Martins dos Santos, Felipe Augusto Soares, Celso Tetsuo Nagase Suzuki, Alessandro Francisco Talamini do Amarante, Katia Denise Saraiva Bresciani
Differences in the efficacy of diagnostic techniques employed in the parasitological examination of feces are a limiting factor of this laboratory procedure in the field of Veterinary Parasitology. To verify advances in this type of examination in dogs, we conducted a study using a new technique (TFGII/Dog). Fifty naturally infected dogs were housed in individual stalls, and their feces were evaluated comparatively using this technique and four other conventional techniques. The TFGII/Dog showed high levels of sensitivity and efficiency, surpassing the diagnostic accuracy of the other techniques with a kappa concordance index of 0...
April 2015: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
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