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https://www.readbyqxmd.com/read/28325219/homeopathy-outperforms-antibiotics-treatment-in-juvenile-scallop-argopecten-ventricosus-effects-on-growth-survival-and-immune-response
#1
José Manuel Mazón-Suástegui, Milagro García-Bernal, Pedro Enrique Saucedo, Ángel Campa-Córdova, Fernando Abasolo-Pacheco
BACKGROUND: Mortality from vibriosis in mollusk production is attributed to pathogenic bacteria, particularly Vibrio alginolyticus. Use of increasingly potent antibiotics has led to bacterial resistance and increased pathogenicity. Alternatives in sanitation, safety, and environmental sustainability are currently under analysis. To-date, homeopathy has been investigated in aquaculture of freshwater fish, but not in marine mollusks. The effect of the homeopathic complexes in the growth, survival, and immune response of the Catarina scallop Argopecten ventricosus were assessed...
February 2017: Homeopathy: the Journal of the Faculty of Homeopathy
https://www.readbyqxmd.com/read/28293192/indole-alkaloids-from-plants-as-potential-leads-for-antidepressant-drugs-a-mini-review
#2
Hazrulrizawati A Hamid, Aizi N M Ramli, Mashitah M Yusoff
Depression is the most common illness observed in the elderly, adults, and children. Antidepressants prescribed are usually synthetic drugs and these can sometimes cause a wide range of unpleasant side effects. Current research is focussed on natural products from plants as they are a rich source of potent new drug leads. Besides Hypericum perforatum (St. John's wort), the plants studied include Passiflora incarnata L. (passion flower), Mitragyna speciosa (kratom), Piper methysticum G. Forst (kava) and Valeriana officinalis L...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28284791/treatment-and-management-of-liver-diseases-by-khmer-traditional-healers-practicing-in-phnom-penh-area-cambodia
#3
François Chassagne, Eric Deharo, Hieng Punley, Geneviève Bourdy
ETHNOPHARMACOLOGICAL RELEVANCE: Liver disorders are a major health problem in Cambodia, where some patients prefer to seek treatment from traditional healers. The aim of the study was to document the knowledge and practices of these healers in four Southern Cambodian provinces. MATERIALS AND METHODS: An ethnopharmacological survey was carried out from September 2015 to January 2016 in Cambodian urban and rural areas. Thirty-three Khmer traditional healers (KTH) were interviewed using a semi-structured questionnaire including socio-demographic data, healer's formation and their professional practice conditions, perception of liver diseases (types and causes of liver disorders, diagnostic methods and symptoms of liver problems), dietary recommendations given to patients, and herbal remedies used to treat them...
March 8, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28271875/in-vivo-selected-pyrazinoic-acid-resistant-m-tuberculosis-strains-harbor-missense-mutations-in-the-aspartate-decarboxylase-pand-and-the-unfoldase-clpc1
#4
Pooja Gopal, Rokeya Tasneen, Michelle Yee, Jean-Philippe Lanoix, Jansy Passiflora Sarathy, George Rasic, Liping Li, Veronique Dartois, E Nuermberger, Thomas Dick
Through mutant selection on agar containing pyrazinoic acid (POA), the bioactive form of the prodrug pyrazinamide (PZA), we recently showed that missense mutations in the aspartate decarboxylase PanD and the unfoldase ClpC1, and loss-of-function mutation of polyketide synthases Mas and PpsA-E involved in phthiocerol dimycocerosate synthesis, cause resistance to POA and PZA in Mycobacterium tuberculosis. Here we first asked whether these in vitro-selected POA/PZA-resistant mutants are attenuated in vivo, to potentially explain the lack of evidence of these mutations among PZA-resistant clinical isolates...
March 8, 2017: ACS Infectious Diseases
https://www.readbyqxmd.com/read/28254981/genome-sequence-of-euphorbia-mosaic-virus-from-passionfruit-and-euphorbia-heterophylla-in-florida
#5
J E Polston, M A Londoño, A L Cohen, M Padilla-Rodriguez, K Rosario, M Breitbart
Euphorbia mosaic virus (EuMV) was found in a symptomatic passionfruit (Passiflora edulis) plant from Homestead, Florida, USA, as well as in the symptomatic weed Euphorbia heterophylla This is the first identification of EuMV in Florida and the United States and the first report of a natural infection of passionfruit by EuMV.
March 2, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28199443/secondary-structure-of-nrdna-internal-transcribed-spacers-as-a-useful-tool-to-align-highly-divergent-species-in-phylogenetic-studies
#6
Giovanna C Giudicelli, Geraldo Mäder, Gustavo A Silva-Arias, Priscilla M Zamberlan, Sandro L Bonatto, Loreta B Freitas
Recently, it has been suggested that internal transcribed spacer (ITS) sequences are under selective constraints to preserve their secondary structure. Here, we investigate the patterns of the ITS nucleotide and secondary structure conservation across the Passiflora L. genus to evaluate the potential use of secondary structure data as a helpful tool for the alignment in taxonomically complex genera. Considering the frequent use of ITS, this study also presents a perspective on future analyses in other plant groups...
February 13, 2017: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/28192885/polyphenols-rich-passiflora-leschenaultii-leaves-modulating-farnesoid-x-receptor-and-pregnane-x-receptor-against-paracetamol-induced-hepatotoxicity-in-rats
#7
Saravanan Shanmugam, Dhivya Sivaraj, Bruno Dos Santos Lima, Paula Dos Passos Menezes, Yasmim Maria Barbosa Gomes de Carvalho, Adriano Antunes de Souza Araújo, Narendra Narain, Mairim Russo Serafini, Lucindo José Quintans Júnior, Luciana Scotti, Marcus Tulius Scotti, Thangaraj Parimelazhagan
The hepatoprotective effect of P. leschenaultii. (DC) leaves was investigated in rats under paracetamol induced oxidative stress. Leaf acetone extract (200 and 400mg/kg) were administered daily via gavage for 14days before paracetamol (2000mg/kg, p.o.) treatment. After the experiment, the levels of serum biochemical parameters and enzymatic antioxidant levels were determined. Furthermore, liver tissues were analyzed histopathologically. Additionally, the molecular docking studies of the identified compounds against PXR and FXR proteins were also performed...
April 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28189068/passiflora-tarminiana-fruits-reduce-uvb-induced-photoaging-in-human-skin-fibroblasts
#8
Karent Bravo, Luisa Duque, Federico Ferreres, Diego A Moreno, Edison Osorio
Skin aging is a complex process that is strongly affected by UV radiation, which stimulates the production of reactive oxygen species (ROS) in the epidermis and dermis and subsequently causes skin damage. Among the major consequences are increased collagen degradation and reduced collagen synthesis. Previous reports have demonstrated the beneficial effects of polyphenols for healthy skin. Passiflora tarminiana Coppens & V.E. Barney, a species of the Passifloraceae family, is widely distributed in South America and is rich in flavonoids...
February 3, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28179114/medicinal-plants-used-to-treat-snakebite-in-central-america-review-and-assessment-of-scientific-evidence
#9
REVIEW
Peter Giovannini, Melanie-Jayne R Howes
ETHNOPHARMACOLOGICAL RELEVANCE: Every year between 1.2 and 5.5 million people worldwide are victims of snakebites, with about 400,000 left permanently injured. In Central America an estimated 5,500 snakebite cases are reported by health centres, but this is likely to be an underestimate due to unreported cases in rural regions. The aim of this study is to review the medicinal plants used traditionally to treat snakebites in seven Central American countries: Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama...
February 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28174623/expression-patterns-of-passiflora-edulis-apetala1-fruitfull-homologues-shed-light-onto-tendril-and-corona-identities
#10
Livia C T Scorza, Jose Hernandes-Lopes, Gladys F A Melo-de-Pinna, Marcelo C Dornelas
BACKGROUND: Passiflora (passionflowers) makes an excellent model for studying plant evolutionary development. They are mostly perennial climbers that display axillary tendrils, which are believed to be modifications of the inflorescence. Passionflowers are also recognized by their unique flower features, such as the extra whorls of floral organs composed of corona filaments and membranes enclosing the nectary. Although some work on Passiflora organ ontogeny has been done, the developmental identity of both Passiflora tendrils and the corona is still controversial...
2017: EvoDevo
https://www.readbyqxmd.com/read/28160755/evaluation-of-anti-osteoporotic-activity-of-butanolic-fraction-from-passiflora-foetida-in-ovariectomy-induced-bone-loss-in-mice
#11
Naseer Ahmad, Raju Chillara, Priyanka Kushwaha, Vikram Khedgikar, Anirudha Karvande, Dharmendra Choudhary, Sulekha Adhikary, Rakesh Maurya, Ritu Trivedi
OBJECTIVE: In this study, we have evaluated the skeletal effects of butanolic fraction (BF) from Passiflora foetida in an estrogen deficient mice bone loss model. STUDY DESIGN: Skeletal effect of BF was studied in ovariectomized (OVx) female Balb/c mice. BF (50 and 100mg/kg/day dose orally) was given for 8 weeks. Micro-architecture of long bones, biomechanical strength, formations of mineralized nodule by bone marrow osteoprogenitor cells, osteoid formation and bone turnover markers were studied...
April 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28137522/herbal-medicines-in-children-with-attention-deficit-hyperactivity-disorder-adhd-a-systematic-review
#12
REVIEW
Dennis Anheyer, Romy Lauche, Dania Schumann, Gustav Dobos, Holger Cramer
OBJECTIVE: The purpose of this review is to identify evidence in herbal therapy in the treatment of ADHD concerning effectiveness and drug tolerability. METHOD: For this Medline/PubMed, Scopus and the Cochrane Central Register of Controlled Trials (Central) were searched from their inception to 15 July 2016. Only randomized controlled trails (RCT) with children (0-18years) suffering from ADHD were included in this review. RESULTS: Nine RCTs with 464 patients comparing herbal pharmaceuticals to placebo or active control were included...
February 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28106710/banana-passion-fruit-passiflora-mollissima-kunth-l-h-bailey-microencapsulation-phytochemical-composition-and-antioxidant-capacity
#13
Almudena García-Ruiz, Amadeo Girones-Vilaplana, Paola León, Diego A Moreno, Carla M Stinco, Antonio J Meléndez-Martínez, Jenny Ruales
Passiflora mollissima (Kunth) L.H. Bailey is an exotic fruit native to South America, known as taxo in Ecuador. This paper characterizes its flavonoid and carotenoid composition and antioxidant capacity and evaluates the effect of the spray-drying process on its phytochemical composition and antioxidant capacity. A total of 18 flavonoid compounds, nine proanthocyanidins and nine flavan-3-ol monomers, were identified and quantified. Glycosides of (epi)-afzelechin stood out as the most abundant flavonoid. Three carotenoids were identified, with β-carotene having the highest concentration...
January 17, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27918731/effects-of-passiflora-incarnata-and-midazolam-for-control-of-anxiety-in-patients-undergoing-dental-extraction
#14
L-P Dantas, A de Oliveira-Ribeiro, L-M de Almeida-Souza, F-C Groppo
BACKGROUND: Anxiety symptoms are frequently observed in dental patients, whether they are undergoing simple or more invasive procedures such as surgery. This research aimed to compare the effects of Passiflora incarnata and midazolam for the control of anxiety in patients undergoing mandibular third molar extraction. MATERIAL AND METHODS: Forty volunteers underwent bilateral extraction of their mandibular third molars in a randomized, controlled, double-blind, crossover clinical trial...
January 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/27914120/effect-of-glycosylation-on-the-biocatalytic-properties-of-hydroxynitrile-lyase-from-the-passion-fruit-passiflora-edulis-a-comparison-of-natural-and-recombinant-enzymes
#15
Aem Nuylert, Yuko Ishida, Yasuhisa Asano
A hydroxynitrile lyase from the passion fruit Passiflora edulis (PeHNL) was isolated from the leaves and showed high stability in biphasic co-organic solvent systems for cyanohydrin synthesis. Cyanohydrins are important building blocks for the production of fine chemicals and pharmaceuticals. Thus, to enhance production yields of PeHNL for industrial applications, we cloned and expressed recombinant PeHNL in Escherichia coli BL21(DE3) and Pichia pastoris GS115 cells without a signal peptide sequence. The aim of this study is to determine the effect of N-glycosylation on enzyme stability and catalytic properties in microbial expression systems...
December 3, 2016: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/27743253/molecular-identification-of-a-new-begomovirus-infecting-yellow-passion-fruit-passiflora-edulis-in-colombia
#16
Juan Carlos Vaca-Vaca, Emerson Clovis Carrasco-Lozano, Karina López-López
The complete genome sequence of a bipartite begomovirus (genus Begomovirus, family Geminiviridae) infecting yellow passion fruit (Passiflora edulis) in the state of Valle del Cauca (Colombia) has been determined. The complete DNA-A and DNA-B components were determined to be 2600 and 2572 nt in length, respectively. The DNA-A showed the highest nucleotide sequence identity (87.2 %) to bean dwarf mosaic virus (M88179), a begomovirus found in common bean crops in Colombia, and only 77.4 % identity to passion fruit severe leaf distortion virus (FJ972767), a begomovirus identified infecting passion fruit in Brazil...
February 2017: Archives of Virology
https://www.readbyqxmd.com/read/27730025/cytotoxicity-of-methanol-extracts-of-annona-muricata-passiflora-edulis-and-nine-other-cameroonian-medicinal-plants-towards-multi-factorial-drug-resistant-cancer-cell-lines
#17
Victor Kuete, Joachim K Dzotam, Igor K Voukeng, Aimé G Fankam, Thomas Efferth
BACKGROUND: Cancer cells rapidly acquire resistance leading to treatment failures. In the present study, we have evaluated the cytotoxicity of 17 methanol extracts from 11 Cameroonian medicinal plants against the sensitive leukemia CCRF-CEM cells and the best ones were further tested on a panel of 8 other human cancer cell lines, including various MDR phenotypes as well as against the normal AML12 hepatocytes. METHODS: The cytotoxicity of the extracts was determined using a resazurin reduction assay meanwhile flow cytometry was used to measure cell cycle, apoptosis, mitochondrial membrane potential (MMP), and reactive oxygen species...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27713945/piceatannol-is-superior-to-resveratrol-in-promoting-neural-stem-cell-differentiation-into-astrocytes
#18
Daisuke Arai, Ryousuke Kataoka, Satoshi Otsuka, Midori Kawamura, Hiroko Maruki-Uchida, Masahiko Sai, Tatsuhiko Ito, Yoichi Nakao
Piceatannol (3,3',4',5-trans-tetrahydroxystilbene) is a polyphenolic compound abundant in the seeds of passion fruit (Passiflora edulis). Piceatannol is an analogue of resveratrol (3,4',5-trans-trihydroxystilbene) and shares the structural motif and biological activities such as activation of SIRT1. Several studies have shown that piceatannol is more potent than resveratrol. In this study, we examined the effects of piceatannol on neural stem cell differentiation into astrocytes compared with those of resveratrol...
October 12, 2016: Food & Function
https://www.readbyqxmd.com/read/27693740/protective-effects-of-cycloartane-triterpenoides-from-passiflora-edulis-sims-against-glutamate-induced-neurotoxicity-in-pc12-cell
#19
Feng-Qing Xu, Ning Wang, Wei-Wei Fan, Cheng-Ting Zi, Hong-Su Zhao, Jiang-Miao Hu, Jun Zhou
Four new cycloartane triterpenoids, 1α,3β-dihydroxy-16-keto-24(31)-en-cycloartane (1), 31-methoxyl-passifloic acid (2), cyclopassifloside XIV (3), and cyclopassifloside XV (4), together with six known compounds (5-10) were isolated from Passiflora edulis Sims. Their structures were elucidated on the basis of extensive spectroscopic analysis. All the compounds were evaluated for protective effects against damage of PC12 cell induced by glutamate according to traditional usage of the herbal medicine, and the results indicated that cycloartane triterpenoids maybe one of the active compositions of P...
December 2016: Fitoterapia
https://www.readbyqxmd.com/read/27681723/the-effects-of-syzygium-samarangense-passiflora-edulis-and-solanum-muricatum-on-alcohol-induced-liver-injury
#20
Yu-Jie Zhang, Tong Zhou, Fang Wang, Yue Zhou, Ya Li, Jiao-Jiao Zhang, Jie Zheng, Dong-Ping Xu, Hua-Bin Li
Previous studies have shown that fruits have different effects on alcohol metabolism and alcohol-induced liver injury. The present work selected three fruits and aimed at studying the effects of Syzygium samarangense, Passiflora edulis and Solanum muricatum on alcohol-induced liver injury in mice. The animals were treated daily with alcohol and fruit juices for fifteen days. Chronic treatment with alcohol increased the levels of aspartate transaminase (AST), alanine transaminase (ALT), total bilirubin (TBIL), triglyceride (TG), malondialdehyde (MDA), and decreased total protein (TP)...
September 26, 2016: International Journal of Molecular Sciences
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