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https://www.readbyqxmd.com/read/27909829/contrast-enhanced-ultrasound-in-diagnosis-of-primary-hepatic-angiosarcoma
#1
Wenwu Ling, Tingting Qiu, Lin Ma, Chuanfen Lei, Yan Luo
Primary hepatic angiosarcoma (PHA) is a rare malignant tumor that occurs mainly in the elderly, with almost no specific symptoms or tumor markers. Information on the imaging characteristics of this tumor is limited due to its rarity. Therefore, it is difficult to diagnose PHA. So far, its definite diagnosis depends on histopathologic examination combined with immunohistochemical results. Patients with PHA have a poor prognosis in spite of surgical resection of this tumor. In this case report, we present a 72-year-old woman with PHA, focusing on the imaging features of this tumor, especially its enhancement pattern on contrast-enhanced ultrasound images...
December 1, 2016: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/27904196/cutaneous-angiosarcoma-simulating-as-pyoderma-in-a-middle-aged-indian-female-a-rare-case-report
#2
Shweta Rana, Kalpana Gupta, Aekta Shah, Nidheesh Agarwal
No abstract text is available yet for this article.
November 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27902593/angiosarcoma-in-the-chest-radiologic-pathologic-correlation-case-report
#3
Sara Piciucchi, Alessandra Dubini, Sara Tomassetti, Stefano Sanna, Claudia Ravaglia, Angelo Carloni, Christian Gurioli, Carlo Gurioli, Thomas V Colby, Venerino Poletti
RATIONALE: Angiosarcomas are rare, malignant vascular tumors. PATIENT CONCERNS: They represents about 2% of all soft tissue sarcoma, which can often metastasize through the hematogenous route. The radiological features have been analyzed in 4 patients with metastatic angiosarcoma in the chest. DIAGNOSES: The main radiologic findings included nodules, cysts, nodules with halo sign, and vascular tree-in-bud. Morphologic features, as observed in the histologic specimen, have been correlated with radiologic appearance...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27895862/cutaneous-angiosarcoma-metastatic-to-small-bowel-with-nodal-involvement
#4
Vidya A Fleetwood, Jamie C Harris, Minh B Luu
A 77-year-old male with a history of metastatic scalp angiosarcoma presented with intractable gastrointestinal bleeding from a jejunal mass detected on capsule endoscopy. He underwent laparoscopic-assisted resection of the mass. Intraoperatively, an isolated small bowel mass with bulky lymphadenopathy was seen and resected en bloc. Pathology showed a 6.8cm high-grade metastatic angiosarcoma with nodal involvement and negative margins. Angiosarcoma is a sarcoma with a grim prognosis. The incidence is 2% of all soft tissue sarcomas; cutaneous lesions comprise 27% of manifestations and usually appear on head and neck...
2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/27872782/angiosarcoma-arising-in-ovarian-mucinous-tumor-a-challenge-in-intraoperative-frozen-section-diagnosis
#5
Surapan Khunamornpong, Jongkolnee Settakorn, Kornkanok Sukpan, Tip Pongsuvareeyakul, Sumalee Siriaunkgul
Angiosarcoma of the ovary is rare but represents an aggressive type of malignant ovarian neoplasms. The purpose of this report is to describe the features of angiosarcoma arising in mucinous tumor that was misinterpreted as a benign vascular proliferation during the intraoperative consultation. A 45-year-old woman presented with an abdominal mass for 1 month. Exploratory laparotomy was performed. A 35 cm right ovarian mass submitted for intraoperative consultation was a multicystic mucinous tumor with an 8 cm area of hemorrhagic lesion between cystic locules...
2016: Case Reports in Pathology
https://www.readbyqxmd.com/read/27869363/is-the-memorial-sloan-kettering-cancer-centre-mskcc-sarcoma-nomogram-useful-in-an-asian-population
#6
Deanna Wan Jie Ng, Grace Hwei Ching Tan, Claramae Shulyn Chia, Cindy Xindi Lim, Soo Khee Chee, Richard Hong Hui Quek, Mohamad Farid, Melissa Ching Ching Teo
AIM: A nomogram for prediction of 12-year sarcoma-specific survival has been developed based on patients with soft tissue sarcomas treated in Memorial Sloan Kettering Cancer Centre (MSKCC). We aim to evaluate the predictive accuracy of the MSKCC sarcoma nomogram in a cohort of patients treated at an Asian institution. This has not been validated in an Asian population and thus its universal applicability remains unproven. MATERIALS AND METHODS: Between 1990 and 2013, 840 adult patients underwent treatment for primary soft tissue sarcoma (STS) at the National Cancer Centre Singapore...
November 21, 2016: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27867677/bilateral-simultaneous-pseudoangiomatous-stromal-hyperplasia-of-the-breasts-and-axillae-imaging-findings-with-pathological-and-clinical-correlation
#7
Afsaneh Alikhassi, Fereshteh Ensani, Ramesh Omranipour, Alireza Abdollahi
Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a pathology that is usually diagnosed by accident during pathological examination of other breast lesions. PASH is an uncommon and benign tumoral lesion of the mammary stroma that can be pathologically mistaken for other tumours, such as phyllodes, fibroadenoma, and sometimes even angiosarcoma. We report the case of a 45-year-old woman with complaints of huge bilateral breast enlargement. This is a rare case of PASH presenting with gigantomastia and involving bilateral breasts and axillae simultaneously...
2016: Case Reports in Radiology
https://www.readbyqxmd.com/read/27867672/primary-angiosarcoma-of-the-spleen-rare-diagnosis-with-atypical-clinical-course
#8
Filip Kohutek, Ladislav Badik, Branislav Bystricky
Primary angiosarcoma of the spleen is a rare diagnosis with poor prognosis. Morphologically, it demonstrates conventional blood vessel differentiation. We present a case of 65-year-old female who underwent radical splenectomy for primary angiosarcoma of the spleen. After three-year disease-free interval, she was diagnosed with bone-only metastatic disease. Palliative radiotherapy and bisphosphonates kept her disease reasonably stable for another four years. After development of lung metastases, six cycles of single agent doxorubicin kept her progression-free for six years...
2016: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/27858895/awareness-of-primary-spontaneous-hemorrhagic-angiosarcoma-of-the-breast-associated-with-kasabach-merritt-syndrome-in-a-pregnant-woman-by-enhanced-magnetic-resonance-imaging-a-care-compliant-case-report
#9
Wei-Ming Lin, Yu-Hsiang Juan, Yu-Ching Lin, Shir-Hwa Ueng, Yung-Feng Lo, Yun-Chung Cheung
INTRODUCTION: Primary breast angiosarcoma with spontaneous intratumoral bleeding associating with Kasabach-Merritt Syndrome is rarely reported. CASE FINDINGS/PATIENT CONCERNS: We herein present such a case in a 30-year-old pregnant woman who was initially diagnosed to hemangioma at her early gestation. However, the sudden rapid tumor growth was aware of the attention and intended for receiving the breast enhanced magnetic resonance imaging. DIAGNOSES AND INTERVENTIONS: The dynamic MRI enhancement showed inhomogenous enhancement at the periphery of the lobulated tumor on both early and delayed scans, otherwise a large hematoma was revealed at the center...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27845552/breast-angiosarcoma-with-exophytic-growth
#10
Donya Farrokh, Elaheh Modoodi, Yalda Fallah Rastegar
Primary angiosarcoma of the breast is a rare malignant tumor. Diagnostic breast imaging includes mammography and ultrasound, which are usually nonspecific. A 42-year-old woman with angiosarcoma of the breast is presented. Physical findings showed a hard exophytic mass in the upper part of the left breast, with skin discoloration overlaying the mass. Mammography revealed a high density well defined mass in the left breast, without any micro-calcification and speculation. On ultrasound examination, a hypoechoic mass with a well-defined margin and heterogenous echogenicity was detected...
November 2016: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/27836568/the-surgical-management-of-head-and-neck-sarcoma-the-newcastle-experience
#11
R W F Breakey, T P Crowley, I B Anderson, R H Milner, M Ragbir
INTRODUCTION: Head and neck sarcomas are rare and difficult to manage surgically. Factors that influence the prognosis include the type and grade of tumour, resection margins, the anatomical site and patient-specific parameters. We review our experience as plastic surgeons working in a bone and soft-tissue tumour multidisciplinary team (MDT) in managing these tumours surgically. METHODS: Data on all patients with sarcoma of the head or neck managed surgically from 2004 to 2015 was reviewed...
October 5, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27818284/cardiac-angiosarcoma-histopathologic-immunohistochemical-and-cytogenetic-analysis-of-10-cases
#12
Charles Leduc, Sarah M Jenkins, William R Sukov, Jeannette G Rustin, Joseph J Maleszewski
Angiosarcoma (AS) is the most common cardiac sarcoma with differentiation, and is poorly characterized from a molecular genetic standpoint. Prognosis remains poor, owing to several factors including aggressive tumor biology, poor response to adjuvant therapy, and lack of targeted therapy. The clinical, pathologic and molecular cytogenetic features were studied in ten cardiac AS surgically resected at Mayo Clinic (1994-2015) using a whole genome single nucleotide polymorphism based platform (OncoScan). Mean patient age was 47...
November 3, 2016: Human Pathology
https://www.readbyqxmd.com/read/27815481/definitive-radiation-therapy-for-angiosarcoma-of-the-face-and-scalp
#13
Gen Suzuki, Hideya Yamazaki, Hideya Takenaka, Norihiro Aibe, Koji Masui, Takuya Kimoto, Kotoha Tatekawa, Akihiro Nakashima, Tadashi Takenaka, Jun Asai, Satoshi Komori, Makoto Wada, Norito Katoh, Kei Yamada
AIM: To examine the role of radiation therapy (RT) and factors' influence on tumor control for angiosarcoma of the face and scalp (AS-FS). PATIENTS AND METHODS: We reviewed the records of 14 patients with histopathology proven AS-FS (median age=77 years) who underwent RT between 2000 and 2015. A total dose of 60 to 100 Gy was administered in 24 to 50 fractions. The median calculated biological effective dose (BED) was 93 Gy (range=63.25-120) based on α/β=10. The median follow-up was 16 months (range=5-62)...
November 2016: In Vivo
https://www.readbyqxmd.com/read/27814287/a-primary-hepatic-angiosarcoma-mimicking-intrahepatic-cholangiocarcinoma-on%C3%A2-conventional-ultrasound-and-contrast-enhanced-ultrasound-a%C3%A2-case-report-and%C3%A2-review-of-literatures
#14
Hui-Xiong Xu, Chong-Ke Zhao, Le-Hang Guo, Li-Ping Sun
Primary hepatic angiosarcoma (PHA) is a rare malignancy with a badly poor prognosis. The extremely low morbidity and untypical clinical manifestations conduce to a missed diagnosis. The present study reported a case of an adult male patient who was pathologically confirmed to be PHA, which mimicked intrahepatic cholangiocarcinoma on conventional ultrasound and contrast-enhanced ultrasound. Findings on various imaging examinations were carefully evaluated and the associated literatures were also reviewed...
November 4, 2016: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/27795774/-a-case-of-angiosarcoma-of-the-outer-ear
#15
Karima Issara, Zouhour Boughaleb, Nezha Tawfiq, Zineb Bouchbika, Nadia Benchakroun, Hassan Jouhadi, Souha Sahraoui, Abdellatif Benider
Angiosarcoma of the ear is a very rare and locally aggressive malignant tumor. It accounts for 4-5% of cutaneous sarcomas and less than 1% of all sarcomas. Our study aims to describe and discuss diagnostic and therapeutic modalities of this malignancy. We report the clinical case of a 31 year old patient with bulging mass of the pavilion of the left ear. CT scan was in favor of tumor of the pavilion of the ear invading ipsilateral parotid. Histological diagnosis was in favor of angiosarcoma. The treatment consisted of complete surgical resection followed by adjuvant radiotherapy...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27792819/cutaneous-angiosarcoma-of-the-scalp-mimicking-facial-cellulitis
#16
Sheng-Chiao Lin, Ting-Shou Chang
No abstract text is available yet for this article.
October 2016: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/27790305/post-radiation-epithelioid-angiosarcoma-of-the-urinary-bladder-and-prostate
#17
Gang Wang, Peter C Black, Brian F Skinnider, Malcolm M Hayes, Edward C Jones
Angiosarcoma of the lower urinary tract is exceedingly rare. A minority of cases are associated with local radiotherapy. Epithelioid angiosarcoma is a variant of angiosarcoma composed of large rounded epithelioid endothelial cells that are positive for cytokeratin on immunostaining. There are only two cases of post-radiation epithelioid angiosarcoma reported in the urinary bladder, and none in the prostate gland. We report a case of epithelioid angiosarcoma involving the urinary bladder and prostate in a patient with a history of radiotherapy for prostatic adenocarcinoma...
May 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27785659/implications-of-lymph-node-evaluation-in-the-management-of-resectable-soft-tissue-sarcoma
#18
Brett L Ecker, Madalyn G Peters, Matthew T McMillan, Andrew J Sinnamon, Paul J Zhang, Rachel R Kelz, Robert E Roses, Jeffrey A Drebin, Douglas L Fraker, Giorgos C Karakousis
BACKGROUND: The rate of lymph node (LN) metastasis is rare in soft tissue sarcoma, but there are histologic subtypes that metastasize via the lymphatics. The prognostic value of LN evaluation in these high-risk histologies is unknown. METHODS: Resected soft-tissue sarcoma patients with clear cell sarcoma, epithelioid sarcoma, rhabdomyosarcoma, or angiosarcoma (n = 2993) were identified in the National Cancer Data Base (2004-2013). Cox regression evaluated the association of omission of LN assessment (NX) and overall survival (OS)...
October 26, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27780597/myc-immunohistochemistry-in-angiosarcoma-and-atypical-vascular-lesions-practical-considerations-based-on-a-single-institutional-experience
#19
Aaron M Udager, Martin K Ishikawa, David R Lucas, Jonathan B McHugh, Rajiv M Patel
Angiosarcoma (AS) is an uncommon vascular malignancy with an aggressive clinical course. Radiation-associated angiosarcoma (RAAS) and Stewart-Treves syndrome are associated with MYC gene amplification and protein overexpression, while other radiation-associated vascular lesions including atypical vascular lesions (AVL) are not associated with MYC overexpression. In contrast, de novo AS represent a group of molecularly heterogeneous tumours, for which MYC expression has not been extensively examined. In this study, MYC immunohistochemistry (IHC) was performed on representative whole tissue sections of a large retrospective cohort of de novo AS, RAAS, Stewart-Treves syndrome, and AVL and evaluated using a semi-quantitative scoring method...
October 22, 2016: Pathology
https://www.readbyqxmd.com/read/27779174/angiosarcoma-around-hip-joint-prosthesis
#20
Wei Zhu, Bin Feng, Qi Ma, Yu-Long Li, Xi-Tao Song, Xi-Sheng Weng
No abstract text is available yet for this article.
2016: Chinese Medical Journal
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