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https://www.readbyqxmd.com/read/29691261/serum-vancomycin-concentrations-after-oral-and-intracolonic-vancomycin-administration-in-a-patient-with-colonic-discontinuity-and-severe-clostridium-difficile-infection
#1
Katja Wilke, Sina Helbig, Katja de With
PURPOSE: A case of detectable systemic vancomycin levels after oral vancomycin administration but not after intracolonic administration in a patient with colonic discontinuity and severe Clostridium difficile infection (CDI) is reported. SUMMARY: A 63-year-old woman who had recently undergone pancreas-kidney transplantation developed severe CDI after 13 days of meropenem therapy for presumed urosepsis. Meropenem was stopped immediately, and treatment with oral vancomycin (250 mg every 6 hours) was started...
May 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29691242/-to-be-a-woman-is-to-make-a-plan-a-qualitative-study-exploring-mothers-experiences-of-the-child-support-grant-in-supporting-children-s-diets-and-nutrition-in-south-africa
#2
Wanga Zembe-Mkabile, Rebecca Surender, David Sanders, Rina Swart, Vundli Ramokolo, Gemma Wright, Tanya Doherty
Food security and good nutrition are key determinants of child well-being. There is strong evidence that cash transfers such as South Africa's Child Support Grant (CSG) have the potential to help address some of the underlying drivers of food insecurity and malnutrition by providing income to caregivers in poor households, but it is unclear how precisely they work to affect child well-being and nutrition. We present results from a qualitative study conducted to explore the role of the CSG in food security and child well-being in poor households in an urban and a rural setting in South Africa...
April 24, 2018: BMJ Open
https://www.readbyqxmd.com/read/29690987/-ankylosing-spinal-fractures-may-result-in-perforation-of-oesophagus
#3
Morten Mølgaard, Kamilla Truong, Kristian Høy
Oesophageal lesions due to spinal fractures are very rare and easily overlooked. In this case report a woman was involved in a minor car accident, and she was primarily examined at the accident and emergency department with no signs of fractures. Ten days later, she was readmitted due to high infection counts and back pain. She had an unstable fracture of Th4 and a perforation of the oesophagus due to ankylosing fractures. The case emphasises the need to pay attention to a possible development of secondary oesophageal perforation in ankylosing spines and unstable fractures, and the need for a special attention when examinating this group of patients...
April 9, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29690917/health-consequences-for-mother-and-baby-of-substantial-pre-conception-weight-loss-in-obese-women-study-protocol-for-a-randomized-controlled-trial
#4
Sarah Price, Alison Nankervis, Michael Permezel, Luke Prendergast, Priya Sumithran, Joseph Proietto
BACKGROUND: Current guidelines for the management of obesity in women planning pregnancy suggest lifestyle modification before conception. However, there is little evidence that lifestyle modification alters pregnancy outcomes. Bariatric surgery results in significant weight loss. This appears to reduce the risk of adverse pregnancy outcomes for the mother but may increase the risk of adverse outcomes for the infant. In order to reduce the risks of obesity-related adverse pregnancy outcomes for both mother and offspring, alternative approaches to the management of obesity in women planning pregnancy are needed...
April 24, 2018: Trials
https://www.readbyqxmd.com/read/29690864/radiogenic-angiosarcoma-of-the-breast-case-report-and-systematic-review-of-the-literature
#5
Askin Dogan, Peter Kern, Beate Schultheis, Günther Häusler, Günther A Rezniczek, Clemens B Tempfer
BACKGROUND: Radiogenic angiosarcoma of the breast (RASB) is a rare late sequela of local irradiation of the breast or chest wall after breast cancer. The prognosis of women with RASB is poor and there is no standardized therapy for this type of malignancy. CASE PRESENTATION: We present the case of a 54 year old woman with RASB (poorly differentiated angiosarcoma of the left breast; pT1, pNX, M0, L0, V0) and a history of invasive-ductal cancer of the left breast (pT1b, G2, pN0, ER positive, PR positive, HER-2/neu negative) treated in July 2012 with breast-conserving surgery, adjuvant chemotherapy with 6 cycles of epirubicin and cyclophosphamide, adjuvant irradiation of the left breast with 50 Gray, and adjuvant endocrine therapy with an aromatase inhibitor...
April 24, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29690814/concurrent-progressive-multifocal-leukoencephalopathy-and-central-nervous-system-infiltration-by-multiple-myeloma-a-case-report
#6
Yanira Ruiz-Heredia, Beatriz Sanchez-Vega, Santiago Barrio, María Linares, Inmaculada Rapado, Esteban Braggio, Keith Stewart, M Dolores Folgueira, Ana Ramos, Luis Collado, Juan Ruiz, Oscar Toldos, Aurelio Hernandez-Lain, Joaquin Martinez-Lopez
Progressive multifocal leukoencephalopathy rarely occurs in patients with multiple myeloma. Intracranial central nervous system invasion is also an uncommon event in multiple myeloma, occurring in less than 1% of cases. We describe herein an exceptional case of coexisting progressive multifocal leukoencephalopathy and intraparenchymal central nervous system myeloma infiltration. A 73-year-old woman with relapsed multiple myeloma was treated with 15 cycles of lenalidomide and dexamethasone, but therapy had to be stopped because of a hip fracture after a fall...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29690773/therapeutic-inertia-in-antiplatelet-therapy-in-patients-with-a-cardiovascular-event-attended-in-an-emergency-department
#7
José Antonio García-Macías, Antonio Palazón-Bru, María Ángeles Carbonell-Torregrosa, Miguel Navarro-Juan, Vicente Francisco Gil-Guillén
OBJECTIVE: As very few studies have assessed therapeutic inertia (TI) in antiplatelet therapy in patients in secondary cardiovascular prevention, we designed a study in our hospital emergency department to quantify its magnitude and its associated factors. METHODS: This descriptive cross-sectional observational study involved a sample of 223 patients with a history of cardiovascular disease and recommendation for antiplatelet therapy who attended the emergency department in a Spanish region in 2016...
April 25, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29689473/severe-aseptic-temporal-lobe-encephalitis-on-fingolimod
#8
Dalia L Rotstein, Aditya Bharatha, Daniel Selchen
We report the case of an MS patient with aseptic temporal lobe encephalitis while on treatment with fingolimod. This 49-year-old woman developed headache and decreasing level of consciousness after 3.5 years of fingolimod therapy. Imaging, CSF studies, and rapid clinical response to acyclovir suggested a viral etiology, although CSF cultures and viral PCR were negative. This case illustrates the potential for severe manifestations of infectious illnesses on fingolimod, which may have a predilection for the CNS and also include herpes virus infections, cryptococcus, and PML...
April 16, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29689472/autonomic-dysreflexia-following-acute-myelitis-due-to-neuromyelitis-optica
#9
Julio C Furlan
BACKGROUND: Cardiovascular autonomic dysfunction is a relatively common secondary complication of tetraplegia. In addition to low baseline arterial blood pressure, tetraplegics can develop sudden-onset hypertensive episodes associated with a variety of symptoms and signs (so-called autonomic dysreflexia). Unfortunately, this potentially life-threatening medical entity is often overlooked and mismanaged. With this, a case of typical presentation of autonomic dysreflexia in an individual with acute severe cervical spinal cord impairment due to neuromyelitis optica (NMO) is reported and discussed...
April 16, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29689406/hyperperfusion-syndrome-after-trapping-with-high-flow-bypass-for-a-giant-paraclinoid-internal-carotid-artery-aneurysm
#10
Masanao Mohri, Toshiya Ichinose, Naoyuki Uchiyama, Kouichi Misaki, Iku Nambu, Yasushi Takabatake, Mitsutoshi Nakada
BACKGROUND: Hyperperfusion syndrome associated with aneurysm surgery is rare. The occurrence of the syndrome after trapping with high-flow bypass has not been described previously. Herein, we present a case of the syndrome occurring after trapping with high-flow bypass of an unruptured giant paraclinoid internal carotid artery (ICA) aneurysm. CASE DESCRIPTION: The patient was a 68-year-old woman with progressive loss of vision in her left eye. After a diagnosis of a left giant ICA aneurysm, she underwent successful trapping with high-flow bypass...
April 21, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29689402/intradural-lumbar-migration-of-an-intracranial-neurosurgical-hemostatic-clip-associated-with-lumbosciatic-pain
#11
Mourad Ould-Slimane, Martin Petit, Gaëtan Tesson, Jordane Mouton, Rémi Gauthé
BACKGROUND: Clips implanted during intracranial neurosurgical procedures sometimes migrate intradurally with rare cases of spinal migration. The appearance of radicular symptoms of topography concordant with the position of the foreign body leads to discussion about the optimal therapeutic strategy. CASE DESCRIPTION: We report the case of a 52-year-old woman suffering from L5 radicular pain resistant to medical treatment in the presence of L4L5 lumbar stenosis and a neurosurgical clip migrated to the L5S1 level...
April 21, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29688953/newly-diagnosed-primary-gum-lymphoma-on-fdg-pet-ct
#12
Jianhua Zhang, Yan Fan, Meng Liu, Qian Li, Rongfu Wang
An 81-year-old woman presented a 2-month history of left upper gum swelling. Biopsy of the lesion revealed the diffuse large B-cell lymphoma. F-FDG PET/CT scan showed the abnormal high uptake at the left upper gum.
April 23, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29688952/incidental-detection-of-an-unusual-case-of-b-cell-lymphoma-of-the-urachal-remnant-on-18f-fdg-pet-ct
#13
Shelvin Kumar Vadi, Rajender Kumar, Bhagwant Rai Mittal, Harmandeep Singh, Amanjit Bal, Gaurav Prakash, Anish Bhattacharya
Neoplasms arising from the urachus are extremely rare. We present a case of a young woman with mild abdominal pain and a palpable swelling in the mid abdomen with incidental detection of a subumbilical mass. Repeated fine-needle aspiration cytology failed to reveal the true nature of the lesion. F-FDG PET/CT showed tracer uptake in the cranial end of urachal remnant lesion. Core biopsy from the site with maximal FDG uptake turned out to be lymphomatous involvement in urachus, which is extremely rare and previously unreported...
April 23, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29688948/hepatic-hemangioma-on-spect-myocardial-perfusion-imaging
#14
Susan Taylor, Tricia Francisco, Janet A Munroe, Hadyn T Williams
Extracardiac uptake on SPECT MPI, seen with physiologic radiotracer distribution, benign or malignant neoplasm, infection, inflammation, or granulomatous disease, may confound the accuracy of MPI or lead to unsuspected pathology. A 38-year-old woman with end-stage renal disease on hemodialysis had SPECT MPI for renal transplant preoperative risk stratification, showing left anterior descending artery ischemia and an intense extracardiac soft tissue focus adjacent to the diaphragmatic right ventricle concerning for focal infection related to prior coronary or gastric surgeries or tumor...
April 23, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29688922/the-use-of-high-frequency-percussive-ventilation-for-whole-lung-lavage-a-case-report
#15
Sudhakar Kinthala, Mark Liang, Felix Khusid, Sebron Harrison
Whole-lung lavage (WLL) remains the gold standard in the treatment of pulmonary alveolar proteinosis. However, anesthetic management during WLL can be challenging because of the risk of intraoperative hypoxemia and various cardiorespiratory complications of 1-lung ventilation. Here, we describe a novel strategy involving the application of high-frequency percussive ventilation using a volumetric diffusive respirator (VDR-4) during WLL in a 47-year-old woman with pulmonary alveolar proteinosis. Our observations suggest that high-frequency percussive ventilation is a potentially effective ventilation strategy during WLL that may reduce the risk of hypoxemia and facilitate lavage...
April 23, 2018: A&A practice
https://www.readbyqxmd.com/read/29688898/vaginal-myomectomy-to-resolve-bladder-outlet-obstruction-50-years-after-hysterectomy
#16
Shorty Johansson, Rustin Walters, Kaitlyn Mayer, Stuart Shippey
BACKGROUND: Leiomyomas can develop after hysterectomy and, when located in the bladder, can result in voiding dysfunction and incontinence. CASE: Fifty years after a hysterectomy, a 77-year-old woman presented with a 1-year history of urinary retention requiring self-catheterization and bothersome urinary incontinence. Multiple imaging modalities demonstrated a well-circumscribed 2-cm mass abutting the bladder beneath the trigone. After ureteral stent placement, we excised the nonpalpable mass using ultrasound guidance...
April 23, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29688849/cryptococcoma-of-a-transplanted-kidney-in-a-patient-presenting-with-recurrent-urinary-tract-infection-a-case-report
#17
Albert Z Muranda, Ludolf Greeff, Mike M Sathekge, Thabo Lengano, Victor O L Karusseit
BACKGROUND: Cryptococcosis is an important opportunistic infection of organ transplant recipients. It is the third most common fungal infection of transplant patients and occurs especially in kidney recipients. Cryptococcus neoformans is a ubiquitous fungus which infects humans by inhalation of spores. C. gattii has more recently been recognised as a pathogen. Infection commonly is disseminated affecting mainly the central nervous system and the lungs. Cryptococcoma, a localised form of the disease, has been described in various organs...
April 23, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29688834/reducing-body-image-related-distress-in-women-with-breast-cancer-using-a-structured-online-writing-exercise-results-from-the-my-changed-body-randomized-controlled-trial
#18
Kerry A Sherman, Astrid Przezdziecki, Jessica Alcorso, Christopher Jon Kilby, Elisabeth Elder, John Boyages, Louise Koelmeyer, Helen Mackie
Purpose Breast cancer treatment adverse effects result in one in three survivors experiencing body image-related distress (BID) that negatively impacts on a woman's ability to recover after cancer and into survivorship. My Changed Body (MyCB) is a Web-based psychological intervention to alleviate BID and improve body appreciation in survivors of breast cancer (BCSs) through a single-session, self-compassion focused writing activity. This randomized controlled trial evaluated the impact of MyCB on BID and body appreciation in BCSs...
April 24, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29688644/-the-medical-care-of-transgender-people
#19
REVIEW
David Rabinerson, Tal Fortgang-Hershenhorn, Rinnat Gabbay-Benziv
The phenomenon of the discrepancy between a person's sexual self-perception and his/her genetic sex has been known to medicine since the mid-19th century. Initially, this discrepancy was considered to be a mental disorder. Over time, advances in medical abilities in surgery, hormonal treatment and infertility, have enabled physicians to help those who are affected to fulfill their wish. The present notion is that transsexualism is a solvable problem (whether the desired wish is for a man to become a woman or vice versa)...
April 2018: Harefuah
https://www.readbyqxmd.com/read/29688491/a-case-of-delayed-diagnosis-of-east-african-trypanosomiasis-in-a-dutch-traveller
#20
C A Wijsman, J L J Hanssen, H Scheper, L G Visser, L van Lieshout
We present a case of East-African trypanosomiasis (EAT) in a 56-year-old Dutch woman returning from holiday in Tanzania and Kenya. The diagnosis was delayed due to the lack of suspicion and secondly because of postponed analysis of blood microscopy after negative rapid malaria antigen testing. Second stage trypanosomiasis was ruled out with liquor analysis. She was treated first with pentamidine and shortly thereafter with suramin, after which she recovered. We emphasize the use of thin/thick smear diagnostics in travellers returning from endemic countries...
January 1, 2018: Journal of Travel Medicine
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