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https://www.readbyqxmd.com/read/29134755/analysis-of-the-influence-of-collagen-fibres-in-the-dermis-on-skin-optical-reflectance-by-monte-carlo-simulation-in-a-nine-layered-skin-model
#1
Y Masuda, Y Ogura, Y Inagaki, T Yasui, Y Aizu
BACKGROUND: Collagen fibres in the dermis play an important structural role in the skin. Age-related changes to these fibres cause wrinkles and slackness of facial skin. However, it is not clear how dermal collagen fibres affect skin colour. The purpose of this study was to clarify the influence of altered collagen fibres on skin colour, using both experimental measurement of fibre density and Monte Carlo simulations in an optical model of skin. METHODS: Reflection spectra were measured from the cheeks of 12 Japanese women (22-65 years old) by spectral colorimeter...
November 13, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/29128688/classification-and-analysis-of-the-natural-corner-curving-motion-of-humans-based-on-gait-motion
#2
Yasuhiro Akiyama, Hitoshi Toda, Takao Ogura, Shogo Okamoto, Yoji Yamada
The curving motion of the human body is more complex than gait motion for straight walking. In particular, when human can freely curve corners, the gait motion varies among and even within individuals. However, is it not possible to classify natural curving motion using a statistical method? This study investigates the natural curving motion, encompassing various walking paths selected by subjects, as opposed to previous studies that focused on specific stepping strategies or curving motion under precisely controlled conditions...
October 9, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29125919/autologous-chondrocyte-implantation-sandwich-technique-compared-with-autologous-bone-grafting-for-deep-osteochondral-lesions-in-the-knee
#3
Tom Minas, Takahiro Ogura, Jeff Headrick, Tim Bryant
BACKGROUND: Treating symptomatic osteochondral defects is challenging, especially in young adults with deep (>8-10 mm) empty defects after osteochondritis dissecans (OCD) or collapsed condyles secondary to avascular necrosis (AVN). For this population, osteoarthritis (OA) is inevitable if articular congruence is not restored. PURPOSE: To describe the autologous chondrocyte implantation (ACI) "sandwich" technique with autologous bone grafting (ABG) and compare it with ABG alone for restoration of the osteochondral unit...
November 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29123903/early-evaluation-of-severity-in-patients-with-severe-sepsis-a-comparison-with-septic-shock-subgroup-analysis-of-the-japanese-association-for-acute-medicine-sepsis-registry-jaam-sr
#4
Takehiko Tarui, Yoshihiro Yamaguchi, Koichiro Suzuki, Ryosuke Tsuruta, Hiroto Ikeda, Hiroshi Ogura, Shigeki Kushimoto, Joji Kotani, Shin-Ichiro Shiraishi, Yasushi Suzuki, Kiyotsugu Takuma, Naoshi Takeyama, Seitaro Fujishima, Toshihiko Mayumi, Yasuo Miki, Norio Yamashita, Naoki Aikawa, Satoshi Gando
Aim: The purpose of this subgroup analysis of a Japanese multicenter registry, the Japanese Association for Acute Medicine Sepsis Registry Advanced (JAAM-SR-Advanced), was to identify early outcome indicators for severe sepsis that are useful and more objective than "septic shock." Methods: Among 624 patients with severe sepsis registered in JAAM-SR-Advanced, 554 with valid serum lactate data were retrospectively studied. Hypotension before and after fluid resuscitation and the highest lactate values over the initial 24 h were compared for their ability to predict in-hospital mortality...
October 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29123900/evaluation-of-factors-associated-with-the-difficulty-in-finding-receiving-hospitals-for-traffic-accident-patients-at-the-scene-treated-by-emergency-medical-services-a-population-based-study-in-osaka-city-japan
#5
Yusuke Katayama, Tetsuhisa Kitamura, Kosuke Kiyohara, Taku Iwami, Takashi Kawamura, Sumito Hayashida, Hiroshi Ogura, Takeshi Shimazu
Aim: Although the prolongation of the time between injury and hospital arrival of traffic accident patients can influence their prognosis, factors associated with the difficulty in hospital acceptance of these patients have not been sufficiently evaluated in Japan. Methods: We retrospectively analyzed the population-based ambulance records of all traffic accident patients for whom the Osaka Municipal Fire Department (Osaka City, Japan) dispatched an ambulance in 2013...
October 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29123867/the-qsofa-requires-validation-as-a-promptly-applicable-clinical-criterion
#6
EDITORIAL
Shigeki Kushimoto, Satoshi Gando, Hiroshi Ogura
No abstract text is available yet for this article.
July 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29118284/-an-in-vitro-model-system-for-studying-the-stress-induced-memory-disorder
#7
Akihiko Ogura, Shinichi Saito, Satoshi Kimura, Keiko Tominaga-Yoshino
No abstract text is available yet for this article.
2017: Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica
https://www.readbyqxmd.com/read/29115717/changes-in-liver-function-and-body-composition-by-direct-acting-antiviral-therapy-for-hepatitis-c-virus-infection
#8
Ryosuke Sugimoto, Motoh Iwasa, Nagisa Hara, Yasuyuki Tamai, Kyoko Yoshikawa, Suguru Ogura, Hideaki Tanaka, Akiko Eguchi, Norihiko Yamamoto, Yoshinao Kobayashi, Hiroshi Hasegawa, Yoshiyuki Takei
AIM: Management of low skeletal muscle mass (LSM) is a very important topic since LSM affects patient mortality in liver diseases. Changes in body composition are unexplored in chronic hepatitis C virus (HCV) patients, including those with liver cirrhosis, who receive direct-acting antiviral (DAA) therapy. Body composition measurements and liver function tests were performed before and after DAA therapy. METHODS: Blood examination, visceral fat area (VFA) and extremity skeletal muscle mass were measured using the multi-frequency bioelectrical impedance analysis method: i) at 24 weeks pre DAA therapy; ii) at the start of DAA therapy; iii) at the end of DAA therapy; iv) at 24 weeks post DAA therapy; and v) at 48 weeks post DAA therapy...
November 8, 2017: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/29102541/nonbacterial-thrombotic-endocarditis-complicated-by-cerebral-infarction-in-a-patient-with-adenomyosis-with-high-serum-ca125-level-a-case-report
#9
Kenji Uchino, Takahiro Shimizu, Heisuke Mizukami, Kenji Isahaya, Hana Ogura, Kensuke Shinohara, Yasuhiro Hasegawa
We report a case of a 48-year-old woman with multiple cerebral infarctions caused by nonbacterial thrombotic endocarditis (NBTE) because of adenomyosis with high serum carbohydrate antigen (CA)125 level. Transesophageal echocardiography (TEE) showed a vegetation, 4 mm in diameter, adjacent to the anterior leaflet of the mitral valve on day 2. Soluble CA125 level was elevated to 901 U/mL. Intravenous infusion of unfractionated heparin sodium was started. On day 35, TEE revealed reduction of the vegetation in size, 2 mm in diameter...
November 1, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29100080/validity-of-radial-magnetic-resonance-imaging-to-determine-the-extent-of-bankart-lesions
#10
Akiko Ogura, Toru Morihara, Hiroyoshi Fujiwara, Yuji Arai, Yoshikazu Kida, Hirotoshi Ito, Ryuhei Furukawa, Yukichi Kabuto, Tsuyoshi Sukenari, Toshikazu Kubo
PURPOSE: The objectives were to compare conventional oblique coronal and axial images with radial images to determine the capacities of these modalities for visualizing sites in the glenoid labrum. MATERIALS AND METHODS: The glenoid labra of 45 patients without a labrum injury and 30 patients with Bankart lesions were examined by magnetic resonance imaging using three different sections. RESULTS: The radial images permitted a greater range of assessment of the morphology of the glenoid labrum than the conventional images...
October 20, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29097479/complete-and-draft-genome-sequences-of-eight-oceanic-pseudomonas-aeruginosa-strains
#11
Yohei Kumagai, Susumu Yoshizawa, Keiji Nakamura, Yoshitoshi Ogura, Tetsuya Hayashi, Kazuhiro Kogure
Pseudomonas aeruginosa is one of the most common model bacterial species, and genomes of hundreds of strains of this species have been sequenced to date. However, currently there is only one available genome of an oceanic isolate. Here, we report two complete and six draft genome sequences of P. aeruginosa isolates from the open ocean.
November 2, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29093429/echocardiographic-assessment-of-cardiac-structural-and-functional-abnormalities-in-patients-with-end-stage-renal-disease-receiving-chronic-hemodialysis
#12
Hiroshi Matsuo, Kaoru Dohi, Hirofumi Machida, Hideyuki Takeuchi, Toshikazu Aoki, Hiroyuki Nishimura, Masashi Yasutomi, Michiharu Senga, Takehiko Ichikawa, Kentaro Kakuta, Yasuhide Mizutani, Akiko Tanoue, Naoki Isaka, Kazuki Oosugi, Sukenari Koyabu, Masato Sakurai, Yoshihisa Fukui, Hitoshi Kakimoto, Tadafumi Sugimoto, Takahiro Ohnishi, Tomohiro Murata, Eiji Ishikawa, Ryuji Okamoto, Tomomi Yamada, Toru Ogura, Yuki Nishimura, Takashi Tanigawa, Shinsuke Nomura, Masakatsu Nishikawa, Masaaki Ito
BACKGROUND: The aim of this study was to assess the echocardiographic characteristics of chronic hemodialysis (HD) patients with end-stage renal disease (ESRD) in a multicenter prospective cohort study.Methods and Results:Three hundred and fifteen patients with ESRD (67.9±10.6 years, 47.6% male) on chronic HD for ≥1 year were examined on transthoracic echocardiography, including Doppler-derived aortic valve area (AVA) measurement. Only 11.5% and 3.4% of all patients had normal left ventricular (LV) geometry and normal LV filling pattern, respectively...
October 31, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29081443/colonoscopy-examination-requires-a-longer-time-in-patients-with-acromegaly-than-in-other-individuals
#13
Masaya Iwamuro, Miho Yasuda, Kou Hasegawa, Satoshi Fujisawa, Kanako Ogura-Ochi, Yuusaku Sugihara, Keita Harada, Sakiko Hiraoka, Hiroyuki Okada, Fumio Otsuka
This study aimed to determine the prevalence of colorectal neoplasms and to investigate the rate of and time required for cecal intubation in patients with acromegaly. A database search performed at our institution identified 29 patients with acromegaly who underwent colonoscopy. Data regarding the endoscopic, biological, and pathological examinations performed were retrospectively reviewed from the clinical records. Subsequently, the rate of and time required for cecal intubation were investigated in 23 patients with acromegaly and compared with the corresponding data of the control group...
October 28, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/29066578/r-spondin1-expands-paneth-cells-and-prevents-dysbiosis-induced-by-graft-versus-host-disease
#14
Eiko Hayase, Daigo Hashimoto, Kiminori Nakamura, Clara Noizat, Reiki Ogasawara, Shuichiro Takahashi, Hiroyuki Ohigashi, Yuki Yokoi, Rina Sugimoto, Satomi Matsuoka, Takahide Ara, Emi Yokoyama, Tomohiro Yamakawa, Ko Ebata, Takeshi Kondo, Rina Hiramine, Tomoyasu Aizawa, Yoshitoshi Ogura, Tetsuya Hayashi, Hiroshi Mori, Ken Kurokawa, Kazuma Tomizuka, Tokiyoshi Ayabe, Takanori Teshima
The intestinal microbial ecosystem is actively regulated by Paneth cell-derived antimicrobial peptides such as α-defensins. Various disorders, including graft-versus-host disease (GVHD), disrupt Paneth cell functions, resulting in unfavorably altered intestinal microbiota (dysbiosis), which further accelerates the underlying diseases. Current strategies to restore the gut ecosystem are bacteriotherapy such as fecal microbiota transplantation and probiotics, and no physiological approach has been developed so far...
October 24, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/29064674/heterogeneity-between-two-%C3%AE-subunits-of-%C3%AE-2%C3%AE-2-human-hemoglobin-and-o2-binding-properties-raman-1-h-nuclear-magnetic-resonance-and-terahertz-spectra
#15
Shigenori Nagatomo, Kazuya Saito, Kohji Yamamoto, Takashi Ogura, Teizo Kitagawa, Masako Nagai
Following a previous detailed investigation of the β subunit of α2β2 human adult hemoglobin (Hb A), this study focuses on the α subunit by using three natural valency hybrid α(Fe(2+)-deoxy/O2)β(Fe(3+)) hemoglobin M (Hb M) in which O2 cannot bind to the β subunit: Hb M Hyde Park (β92His → Tyr), Hb M Saskatoon (β63His → Tyr), and Hb M Milwaukee (β67Val → Glu). In contrast with the β subunit that exhibited a clear correlation between O2 affinity and Fe(2+)-His stretching frequencies, the Fe(2+)-His stretching mode of the α subunit gave two Raman bands only in the T quaternary structure...
November 7, 2017: Biochemistry
https://www.readbyqxmd.com/read/29058634/three-dimensional-ultrastructure-of-capillary-endothelial-glycocalyx-under-normal-and-experimental-endotoxemic-conditions
#16
Hideshi Okada, Genzou Takemura, Kodai Suzuki, Kazumasa Oda, Chihiro Takada, Yasuaki Hotta, Nagisa Miyazaki, Akiko Tsujimoto, Isamu Muraki, Yoshiaki Ando, Ryogen Zaikokuji, Atsumu Matsumoto, Hiroki Kitagaki, Yuto Tamaoki, Takahiro Usui, Tomoaki Doi, Takahiro Yoshida, Shozo Yoshida, Hiroaki Ushikoshi, Izumi Toyoda, Shinji Ogura
BACKGROUND: Sugar-protein glycocalyx coats healthy endothelium, but its ultrastructure is not well described. Our aim was to determine the three-dimensional ultrastructure of capillary endothelial glycocalyx in the heart, kidney, and liver, where capillaries are, respectively, continuous, fenestrated, and sinusoidal. METHODS: Tissue samples were processed with lanthanum-containing alkaline fixative, which preserves the structure of glycocalyx. RESULTS: Scanning and transmission electron microscopy revealed that the endothelial glycocalyx layer in continuous and fenestrated capillaries was substantially thicker than in sinusoids...
October 23, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29057795/the-effect-of-piceatannol-from-passion-fruit-passiflora-edulis-seeds-on-metabolic-health-in-humans
#17
Munehiro Kitada, Yoshio Ogura, Hiroko Maruki-Uchida, Masahiko Sai, Taeko Suzuki, Keizo Kanasaki, Yuna Hara, Hiromi Seto, Yuka Kuroshima, Itaru Monno, Daisuke Koya
Animal studies have shown the beneficial effects of piceatannol on metabolic health; however, there is a lack of human studies designed to examine these effects. The objective of this study was to investigate the effects of piceatannol on metabolic health in humans. This randomized, placebo-controlled study was conducted on 39 subjects, including 10 overweight men and 9 overweight women (BMI ≥ 25), as well as 10 non-overweight men and 10 non-overweight women (BMI < 25). Subjects received piceatannol (20 mg/day) or placebo capsules for eight weeks in a random order...
October 18, 2017: Nutrients
https://www.readbyqxmd.com/read/29057778/survey-of-careers-and-achievements-on-delegates-in-jsrt-international-delegation-projects
#18
Masato Kobayashi, Rie Tanaka, Kosuke Matsubara, Shigeaki Morioka, Katsumi Tsujioka, Hidetaka Arimura, Katsuhiko Ueda, Akio Ogura, Tosiaki Miyati
Japanese society of radiological technology (JSRT) categorizes three international delegation projects; short-term studying abroad program (STSAP), international academic society visit program (overseas) (IASVP), and international internship visit program (Stanford University) (IIVP) for driving globalization of JSRT. In this survey, we conducted a questionnaire evaluating effectiveness of the international delegations. The survey covered 50 delegates of STSAP, 180 delegates of IASVP, and 100 delegates of IIVP...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/29056554/development-of-a-novel-schiff-base-derivative-for-enhancing-the-anticancer-potential-of-5-aminolevulinic-acid-based-photodynamic-therapy
#19
Yusei Shinohara, Yoshio Endo, Chiaki Abe, Ikkyu Shiba, Masahiro Ishizuka, Tohru Tanaka, Yutaka Yonemura, Shun-Ichiro Ogura, Masahide Tominaga, Hisatsugu Yamada, Yoshihiro Uto
5-Aminolevulinic acid (ALA), a precursor of protoporphyrin IX (PpIX), is now widely used for photodynamic diagnosis (ALA-PDD) and photodynamic therapy (ALA-PDT) of various cancers. Recently, we found that treatment of cancer cells with the Schiff base derivative TX-816 along with ALA could significantly increase the efficacy of ALA-PDT. This enhancing effect of TX-816 on ALA-PDT is attributed to 3,5-dichlorosalicylaldehyde (DCSA), a molecule produced by the degradation of TX-816. Similar to TX-816, DCSA significantly enhances the effect of ALA-PDT...
October 19, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29055507/corrigendum-to-thaumasiovibrio-occultus-gen-nov-sp-nov-and-thaumasiovibrio-subtropicus-sp-nov-within-the-family-vibrionaceae-isolated-from-coral-reef-seawater-off-ishigaki-island-japan-syst-appl-microbiol-40-5-2017-290-296
#20
A K M Rohul Amin, Mami Tanaka, Nurhidayu Al-Saari, Gao Feng, Sayaka Mino, Yoshitoshi Ogura, Tetsuya Hayashi, Pedro M Meirelles, Fabiano L Thompson, Bruno Gomez-Gil, Toko Sawabe, Tomoo Sawabe
No abstract text is available yet for this article.
October 18, 2017: Systematic and Applied Microbiology
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