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JOURNAL ARTICLE
Sara Nieves Ramos Cózar, Rafael Martín Masot, Begoña Rodríguez Gallego, Leticia Rubio, Juan Luis Cabanillas Moruno, Víctor Manuel Navas López
INTRODUCTION: Inflammatory bowel disease (IBD) is a chronic disorder that can lead to periods of work-related temporary disability (TD), which may result in the need for permanent disability. The objective was to assess the impact of IBD on patients' temporary disability by analyzing periods, duration, and causes. It also investigates risk factors influencing the severity, frequency, and duration of flare-ups and associated complications in IBD patients. METHOD: The study includes patients aged 18 to 65, with at least 1 day of TD in 2019 (Pre-COVID), referred or not by UMEVI, due to reasons related to IBD...
May 5, 2024: Gastroenterología y Hepatología
#2
JOURNAL ARTICLE
F J Fernández-Pérez, N Fernández Moreno, E Soria López, F J Rodriguez-González, F J Fernández-Galeote, A Lifante Oliva, C Ruíz Hernández, E Escalante Quijaite, F Rivas Ruiz
INTRODUCTION: Granulocyte and monocyte adsorptive apheresis (GMA) removes neutrophils and monocytes from peripheral blood, preventing their incorporation into the inflamed tissue also influencing cytokine balance. Published therapeutic efficacy in ulcerative colitis (UC) is more consistent than in Crohn´s disease (CD). We assessed clinical efficacy of GMA in UC and CD 4 weeks after last induction session, at 3 and 12 months, sustained remission and corticosteroid-free remission. PATIENTS AND METHOD: Retrospective observational study of UC and CD patients treated with GMA...
May 4, 2024: Gastroenterología y Hepatología
#3
JOURNAL ARTICLE
Iago Rodríguez Lago, Claudia Herrera de Guise, Maia Boscá Watts, Cristina Rodríguez, Eduardo Leo Carnerero, María Calvo Íñiguez, Fiorella Cañete, Silvia Chacón, Camila Cuarán, Ainara Elorza, Elena Guerra Del-Río, Eva Iglesias, Damián Sánchez, Manuel Barreiro de Acosta, Daniel Ginard, José Luis Cabriada
OBJECTIVE: Granulocyte-monocyte apheresis (GMA) has shown to be safe and effective in ulcerative colitis (UC), also in combination with biologics, mainly with anti-TNF. The aim of this study was to evaluate the efficacy and safety of combining GMA after primary non-response (PNR) or loss of response (LOR) to ustekinumab (UST) in patients with UC. PATIENTS AND METHODS: A retrospective study was performed in 12 IBD Units, including all patients with refractory UC or unclassified IBD (IBD-U) who received combined GMA plus UST...
May 4, 2024: Gastroenterología y Hepatología
#4
JOURNAL ARTICLE
Cristina Suárez Ferrer, Francisco Mesonero Gismero, Berta Caballol, Maria Pilar Ballester, Iria Bastón Rey, Andrés Castaño García, Jose Miranda Bautista, Rosa Saiz Chumillas, Jose Manuel Benitez, Laura Sanchez Delgado, Alicia López García, Cristina Rubin de Celix, Inmaculada Alonso Abreu, Luigi Melcarne, Rocío Plaza Santos, Miquel Marques Camí, Antonio Caballero Mateos, César Gómez Díez, Margalida Calafat, Horacio Alonso Galan, Pablo Vega Vilaamil, Beatriz Castro Senosiain, Andrea Guerro Moya, Carmen Yolanda Rodriguez Diaz, Katerina Spicakova, Noemi Manceñdo Marcos, Gema Molina, Luisa de Castro Parga, Andres Rodriguez Angulo, Lidia Cuevas Del Campo, Maria Del Carmen Rodriguez Grau, Fernando Ramirez, Barbara Gomez Pastrana, Irene Gonzalez Partida, Belen Botella Mateu, Elena Peña Gonzalez, Eduardo Iyo, Alfonso Elosua Gonzalez, Empar Sainz Arnau, Luis Hernandez Villalba, Pablo Perez Galindo, Leyanira Torrealba Medina, Sara Monsalve Alonso, Jose Antonio Olmos Perez, Carmen Dueñas Sadornil, Laura Garcia Ramirez, María Dolores Martín-Arranz, Antonio López Sanroman, Agnès Fernández, Victor Merino Murgui, Cristina Calviño Suárez, Pablo Florez, María Elena Lobato Matilla, Beatriz Sicilia, Pilar Soto Escribano, Carlos Maroto Martin, Míriam Mañosa, Manuel Barreiro De Acosta
INTRODUCTION: Biological therapies used for the treatment of inflammatory bowel disease (IBD) have shown to be effective and safe, although these results were obtained from studies involving mostly a young population, who are generally included in clinical trials. The aim of our study was to determine the efficacy and safety of the different biological treatments in the elderly population. METHODS: Multicenter study was carried out in the GETECCU group.Patients diagnosed with IBD and aged over 65 years at the time of initiating biological therapy (infliximab, adalimumab, golimumab, ustekinumab or vedolizumab) were retrospectively included...
May 4, 2024: Gastroenterología y Hepatología
#5
REVIEW
Jordi Serra, Ariadna Aguilar, Elizabeth Barba, Constanza Ciriza de Los Ríos, Laura Garcia Pravia, Vicente Martínez, Blanca Serrano Falcón
Functional abdominal pain is a disorder in which central and peripheral sensitization processes converge, leading to hypersensitivity and allodynia. Differential diagnosis is made with organic digestive, renal, gynecological, endocrine, or neurological diseases. Treatment should be individualized for each patient. In cases of debilitating pain, therapy combining drugs with different mechanisms of action can be initiated, while in less severe cases, therapy with a progressive introduction of drugs based on clinical response is advised...
April 25, 2024: Gastroenterología y Hepatología
#6
JOURNAL ARTICLE
David Marti-Aguado, Javier Pazó, Alvaro Diaz-Gonzalez, Berta de Las Heras Páez de la Cadena, Andres Conthe, Rocio Gallego Duran, Miguel A Rodríguez-Gandía, Juan Turnes, Manuel Romero-Gomez
No abstract text is available yet for this article.
April 4, 2024: Gastroenterología y Hepatología
#7
M A Valdovinos Díaz, M Amieva-Balmori, R Carmona-Sánchez, E Coss-Adame, O Gómez-Escudero, M González-Martínez, F Huerta-Iga, E Morel-Cerda, J M Remes-Troche, J L Tamayo-de la Cuesta, G Torres-Villalobos, L R Valdovinos-García, G Vázquez-Elizondo, A S Villar-Chávez, J A Arenas-Martínez
INTRODUCTION: Gastroesophageal reflux disease (GERD) is very prevalent in the general population, with a broad spectrum of clinical manifestations, requiring accurate diagnosis and treatment. AIM: The aim of this expert review is to establish good clinical practice recommendations for the diagnosis and personalized treatment of GERD. METHODS: The good clinical practice recommendations were produced by a group of experts in GERD, members of the Asociación Mexicana de Gastroenterología (AMG), after carrying out an extensive review of the published literature and discussing each recommendation at a face-to-face meeting...
April 4, 2024: Revista de Gastroenterología de México
#8
JOURNAL ARTICLE
Claudia Barber Caselles, Ariadna Aguilar Cayuelas, Francisca Yáñez, Luis G Alcala-Gonzalez
No abstract text is available yet for this article.
May 2024: Gastroenterología y Hepatología
#9
JOURNAL ARTICLE
Abel Botelho Quaresma, Ludmila Resende Guedes, Jaqueline Ribeiro de Barros, Júlio Pinheiro Baima, Marcello Imbrizi, Marco Antônio Zerôncio, Paulo Gustavo Kotze, Cristina Flores
BACKGROUND: The most efficient way to prevent complications from inflammatory bowel disease (IBD) is to provide patients with optimized care. Nonetheless, in Brazil, there is no validated methodology for evaluating health services recognized as comprehensive care units (CCU), making it difficult to assess the quality of care provided. OBJECTIVE: To understand the current scenario, map the distribution of centers and identify strengths and weaknesses, considering local and regional characteristics...
2024: Arquivos de Gastroenterologia
#10
REVIEW
Joaquim Prado P Moraes-Filho, Gerson Domingues, Decio Chinzon
BACKGROUND: Gastroesophageal Reflux Disease (GERD) is a prevalent condition in Brazil, affecting 12% to 20% of the urban population, with significant implications for patient quality of life and potential for complications. OBJECTIVE: This paper focuses on the recent update of the Brazilian guidelines for GERD, a necessary revision due to advancements in knowledge and practice since the last publication over a decade ago. The update pays particular attention to the role and safety of proton pump inhibitors (PPIs), acknowledging the growing concerns about their long-term use, adverse events, and overprescription...
2024: Arquivos de Gastroenterologia
#11
JOURNAL ARTICLE
Didia B Cury, Liana C B Cury, Ana C Micheletti, Rogério A Oliveira, José J S Gonçalves
BACKGROUND: Latent tuberculosis (LTB) is a condition where the patient is infected with Mycobacterium tuberculosis but does not develop active TB. There's a possibility of tuberculosis (TB) activation following the introduction of anti-TNFs. OBJECTIVE: To assess the risk of biological therapy inducing LTB during inflammatory bowel diseases (IBD) treatment over 15 years in a high-risk area in Brazil. METHODS: A retrospective study of an IBD patients' database was carried out in a private reference clinic in Brazil...
2024: Arquivos de Gastroenterologia
#12
JOURNAL ARTICLE
Paulo Ricardo Pavanatto Cavassola, Diogo Turiani Hourneaux de Moura, Bruno Salomão Hirsch, Davi Lucena Landim, Wanderley Marques Bernardo, Eduardo Guimarães Hourneaux de Moura
BACKGROUND: Colorectal cancer is the third most common cancer, and prevention relies on screening programs with resection complete resection of neoplastic lesions. OBJECTIVE: We aimed to evaluate the best snare polypectomy technique for colorectal lesions up to 10 mm, focusing on complete resection rate, and adverse events. METHODS: A comprehensive search using electronic databases was conducted to identify randomized controlled trials comparing hot versus cold snare resection for polyps sized up to 10 mm, and following PRISMA guidelines, a meta-analysis was performed...
2024: Arquivos de Gastroenterologia
#13
JOURNAL ARTICLE
H Shafeeq Ahmed
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive and lethal form of cancer with limited prognostic accuracy using traditional factors. This has led to the exploration of innovative prognostic models, including convolutional neural networks (CNNs), in PDAC. CNNs, a type of artificial intelligence algorithm, have shown promise in various medical applications, including image analysis and pattern recognition. Their ability to extract complex features from medical images makes them suitable for improving prognostication in PDAC...
2024: Arquivos de Gastroenterologia
#14
JOURNAL ARTICLE
Cássio Marques Perlin, Larisse Longo, Rutiane Ullmann Thoen, Carolina Uribe-Cruz, Mário Reis Álvares-DA-Silva
BACKGROUND: Alcoholic liver disease (ALD) and metabolic-dysfunction associated steatotic liver disease (MASLD) are common, and gut microbiota (GM) is involved with both. Here we compared GM composition in animal models of MASLD and ALD to assess whether there are specific patterns for each disease. METHODS: MASLD model- adult male Sprague Dawley rats, randomized into two groups: MASLD-control (n=10) fed a standard diet; MASLD-group (n=10) fed a high-fat-choline-deficient diet for 16 weeks...
2024: Arquivos de Gastroenterologia
#15
JOURNAL ARTICLE
Laís Flavia de Souza Gutierres, Marina Rodrigues Montaldi, Weslania Viviane Nascimento, Roberto Oliveira Dantas
BACKGROUND: People recurrently have difficulties swallowing solid medications, which can be associated with the size of the medication and the age and gender of individuals. OBJECTIVE: To evaluate the impact of capsule size and adults' age and gender on oral and pharyngeal capsule transit during capsule swallows. METHODS: Videofluoroscopy was used to measure capsule oral and pharyngeal transit during swallows in 49 healthy individuals (17 men and 32 women), with a mean age of 46 years (ranging from 23 to 88 years)...
2024: Arquivos de Gastroenterologia
#16
JOURNAL ARTICLE
Claudia Teresa Carvente, Maria Lúcia Cardoso Gomes Ferraz, Carlos Fischer de Toledo
BACKGROUND: The treatment of chronic pancreatitis does not consistently solve intestinal abnormalities, and despite the implementation of various therapeutic measures, patients often continue to experience persistent diarrhea. Therefore, it is imperative to recognize that diarrhea may stem from factors beyond pancreatic insufficiency, and intestinal inflammation emerges as a potential contributing factor. OBJECTIVE: The aim of this study was to assess fecal lactoferrin and calprotectin levels as indicators of intestinal inflammation in patients with chronic pancreatitis experiencing persistent diarrhea...
2024: Arquivos de Gastroenterologia
#17
EDITORIAL
Marcelo Averbach, Hélio Moreira Junior, Herbeth José Toledo Silva, Francisco Sérgio Rangel de Paula Pessoa
No abstract text is available yet for this article.
2024: Arquivos de Gastroenterologia
#18
JOURNAL ARTICLE
Jean Félix Piñerúa-Gonsálvez, Rosanna Del Carmen Zambrano-Infantino, Julio César Albornoz-Sandoval, Pedro Waykin Tong-Morao, Mariangel Nohemy León-Hernández, Barbara Daniela Matheus-Alonso, Frank Suárez-López, Yormalis Flores, Santos Neomar Higuera, María Lourdes Ruiz-Rebollo, Mariseli Sulbaran
BACKGROUND: Proton pump inhibitors (PPIs) are widely prescribed worldwide, often resulting in their overuse. Consequently, it is essential to identify the likely causes of this overuse to facilitate their appropriate prescription. OBJECTIVE: This study aims to assess physician prescribing patterns, their knowledge of PPIs, and factors affecting their knowledge. METHODS: An online survey was conducted among Latin American and Spanish physicians, collecting the following data: professional information, patterns of PPI usage, familiarity with published evidence, and the management approach in three hypothetical case-scenarios...
2024: Arquivos de Gastroenterologia
#19
JOURNAL ARTICLE
José Celso Ardengh, Anna Carolina Orsini-Arman, Bruna Haueisen-Figueiredo, Guilherme Camarotti de Oliveira-Canejo, Otávio Micelli-Neto
BACKGROUND: • The ERCP even when done by experienced professionals, fails in 10% of cases. BACKGROUND: • Until the development of the EUS-BD, PTBD had a role as a rescue therapy, despite a high rate of adverse events. BACKGROUND: • The EUS-BD is safe and has similar efficacy, when compared to PTBD and should be performed immediately after ERCP failure. BACKGROUND: • A doctor with skills in both methods (ERCP/EUS) is needed to determine the best EUS-guided therapeutic option...
2024: Arquivos de Gastroenterologia
#20
JOURNAL ARTICLE
Patrícia Zacharias, Daniéla Oliveira Magro, Milena Perussolo, Fernanda da Silva Barbosa Baraúna, Paulo Gustavo Kotze
BACKGROUND: Inflammatory bowel diseases (IBD) have rising incidence and prevalence rates globally. In IBD, there are scarce stu-dies comparing differences between patients according to socioeconomic status. Our aim was to comparatively evaluate hospitalizations, use of biologics and rates of surgery in patients with IBD between public and private healthcare systems. METHODS: Single-center retrospective cohort study in patients with IBD from a tertiary referral unit from Latin America, between 2015 and 2021...
2024: Arquivos de Gastroenterologia
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