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Wine and ageing

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https://www.readbyqxmd.com/read/29140412/alcohol-consumption-and-lung-cancer-risk-in-never-smokers-a-pooled-analysis-of-case-control-studies
#1
José A García Lavandeira, Alberto Ruano-Ravina, Karl T Kelsey, María Torres-Durán, Isaura Parente-Lamelas, Virginia Leiro-Fernández, Maruxa Zapata, José Abal-Arca, Iria Vidal-García, Carmen Montero-Martínez, Margarita Amenedo, Olalla Castro-Añón, Antonio Golpe-Gómez, Rosirys Guzmán-Taveras, Cristina Martínez, Mariano Provencio, María J Mejuto-Martí, Silvia García-García, Alberto Fernández-Villar, María Piñeiro, Juan M Barros-Dios
Background: Lung cancer is the deadliest cancer in developed countries but the etiology of lung cancer risk in never smokers (LCRINS) is largely unknown. We aim to assess the effects of alcohol consumption, in its different forms, on LCRINS. Methods: We pooled six multi-center case-control studies developed in the northwest of Spain. Cases and controls groups were composed of never smokers. We selected incident cases with anatomopathologically confirmed lung cancer diagnoses...
November 13, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29133421/early-neolithic-wine-of-georgia-in-the-south-caucasus
#2
Patrick McGovern, Mindia Jalabadze, Stephen Batiuk, Michael P Callahan, Karen E Smith, Gretchen R Hall, Eliso Kvavadze, David Maghradze, Nana Rusishvili, Laurent Bouby, Osvaldo Failla, Gabriele Cola, Luigi Mariani, Elisabetta Boaretto, Roberto Bacilieri, Patrice This, Nathan Wales, David Lordkipanidze
Chemical analyses of ancient organic compounds absorbed into the pottery fabrics from sites in Georgia in the South Caucasus region, dating to the early Neolithic period (ca. 6,000-5,000 BC), provide the earliest biomolecular archaeological evidence for grape wine and viniculture from the Near East, at ca. 6,000-5,800 BC. The chemical findings are corroborated by climatic and environmental reconstruction, together with archaeobotanical evidence, including grape pollen, starch, and epidermal remains associated with a jar of similar type and date...
November 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29129902/quantification-of-fraglide-1-a-new-functional-ingredient-in-vinegars
#3
Aydan H Yatmaz, Tetsuaki Kinoshita, Akio Miyazato, Masahiro Takagi, Yoshio Tsujino, Fumiaki Beppu, Naohiro Gotoh
Vinegar is a widely used condiment in the world, and is produced from ethanol by acetic acid fermentation. Different fruits, vegetables, cereals, and wines can be used as ingredients for vinegar production. It is known that vinegar has many nutrient components such as organic acids, polyphenols, and aromatic compounds. Because of these bioactive components, it has many health benefits. China has a long history of producing vinegar and has been using it for health products and as medicine. Chinese aromatic Zhenjiang vinegar (Kozu) is produced from sticky rice...
November 13, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/29120125/risk-factors-associated-with-black-tooth-stain
#4
Katica Prskalo, Eva Klarić Sever, Ivan Alerić, Tatjana Antonić Jelić, Ivona Žaja
The aim of the study was to show whether there is any influence of food, drink or drug intake on the formation of tooth discoloration. A total of 500 patients aged 15-25 years were examined to take part in the study. Of these, 60 patients were selected and divided into two groups of 30 patients each. Group 1 included patients with black pigmentation on vestibular/oral tooth surfaces. Group 2 included patients without discoloration (control). Data were recorded in a questionnaire. Atomic absorption spectrometry was used to determine elements in discoloration samples...
March 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29106590/antibody-dependent-cellular-cytotoxicity-adcc-responses-to-seasonal-influenza-vaccination-in-older-adults
#5
Hillary A Vanderven, Sinthujan Jegaskanda, Bruce D Wines, P Mark Hogarth, Sarina Carmuglia, Steven Rockman, Amy W Chung, Stephen J Kent
Background: Older adults are at high-risk of influenza disease, but generally respond poorly to vaccination. Antibody-dependent cellular cytotoxicity (ADCC) may be an important component of protection against influenza infection. An improved understanding of the ADCC response to influenza vaccination in older adults is required. Methods: We studied sera samples from three groups of subjects aged 65 years (n=16-17/group) receiving the 2008/2009 seasonal trivalent influenza vaccine (TIV)...
November 2, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29099824/-changes-in-alcohol-consumption-from-youth-to-adulthood-in-italy
#6
Nadia Olimpi, Stefano Bravi, Allaman Allamani, Fabio Voller
BACKGROUND: alcohol consumption is a significant risk factor for health at all ages. Consumption patterns and associated risks vary across countries and cultures and are affected by socio-demographic characteristics. The objective of the study was to assess changes in alcoholic beverage consumption patterns from youth to adulthood in Italy, and specifically in the North, Central and South-Islands geographic areas. METHODS: subjects who consume wine, beer and spirits/bitters/alcoholic aperitifs, as recorded by the Istat Multipurpose surveys "Aspects of daily life", were grouped into non-drinkers, occasional drinkers and drinkers of at least one glass a day...
July 2017: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/29081890/role-of-diet-and-nutritional-supplements-in-parkinson-s-disease-progression
#7
Laurie K Mischley, Richard C Lau, Rachel D Bennett
OBJECTIVES: The goal of this study is to describe modifiable lifestyle variables associated with reduced rate of Parkinson's disease (PD) progression. METHODS: The patient-reported outcomes in PD (PRO-PD) were used as the primary outcome measure, and a food frequency questionnaire (FFQ) was used to assess dietary intake. In this cross-sectional analysis, regression analysis was performed on baseline data to identify the nutritional and pharmacological interventions associated with the rate of PD progression...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29079079/assessing-cognitive-functioning-in-females-with-rett-syndrome-by-eye-tracking-methodology
#8
Jaana Ahonniska-Assa, Orli Polack, Einat Saraf, Judy Wine, Tamar Silberg, Andreea Nissenkorn, Bruria Ben-Zeev
BACKGROUND: While many individuals with severe developmental impairments learn to communicate with augmentative and alternative communication (AAC) devices, a significant number of individuals show major difficulties in the effective use of AAC. Recent technological innovations, i.e., eye-tracking technology (ETT), aim to improve the transparency of communication and may also enable a more valid cognitive assessment. OBJECTIVES: To investigate whether ETT in forced-choice tasks can enable children with very severe motor and speech impairments to respond consistently, allowing a more reliable evaluation of their language comprehension...
October 10, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29055473/the-effect-of-alcohol-and-red-wine-consumption-on-clinical-and-mri-outcomes-in-multiple-sclerosis
#9
Camilo Diaz-Cruz, Alicia S Chua, Muhammad Taimur Malik, Tamara Kaplan, Bonnie I Glanz, Svetlana Egorova, Charles R G Guttmann, Rohit Bakshi, Howard L Weiner, Brian C Healy, Tanuja Chitnis
BACKGROUND: Alcohol and in particular red wine have both immunomodulatory and neuroprotective properties, and may exert an effect on the disease course of multiple sclerosis (MS). OBJECTIVE: To assess the association between alcohol and red wine consumption and MS course. METHODS: MS patients enrolled in the Comprehensive Longitudinal Investigation of Multiple Sclerosis at the Brigham and Women's Hospital (CLIMB) who completed a self-administered questionnaire about their past year drinking habits at a single time point were included in the study...
October 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29055104/lifetime-alcohol-intake-and-risk-of-non-hodgkin-lymphoma-findings-from-the-melbourne-collaborative-cohort-study
#10
Harindra Jayasekara, Surender Juneja, Allison M Hodge, Robin Room, Roger L Milne, John L Hopper, Dallas R English, Graham G Giles, Robert J MacInnis
Cohort studies have reported inconsistent evidence regarding alcohol intake and risk of non-Hodgkin lymphoma (NHL), mostly based on alcohol intake assessed close to study enrolment. We examined this association using alcohol intake measured from age 20 onwards. We calculated usual alcohol intake for 10-year periods from age 20 using recalled frequency and quantity of beverage-specific consumption for 37,990 participants aged 40-69 years from the Melbourne Collaborative Cohort Study. Cox regression was performed to derive hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between alcohol intake (g/day) and NHL risk...
October 21, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29054583/dietary-resveratrol-increases-mid-life-fecundity-of-female-nothobranchius-guentheri
#11
Youngjoo Lee, Andrew C Drake, Nicholas O Thomas, Lindsey G Ferguson, Patrick E Chappell, Kate Petersen Shay
The decline of female reproductive function is an early phenotype of aging in humans, occurring only midway through the lifespan. Yet the number of women delaying pregnancy continues to rise in industrialized societies due to personal or socioeconomic circumstances, often resulting in subfertility or difficulty conceiving. There are few defined mechanisms associated with this etiology, and equally few effective therapies. To combat this problem, we used a novel emerging model, Nothobranchius guentheri, that recapitulates the age-associated spectrum of changes that adversely affect human fertility...
October 17, 2017: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/29052965/from-vineyard-to-winery-a-source-map-of-microbial-diversity-driving-wine-fermentation
#12
Peter Morrison-Whittle, Matthew R Goddard
Humans have been making wine for thousands of years and microorganisms play an integral part in this process as they not only drive fermentation, but also significantly influence the flavour, aroma, and quality of finished wines. Since fruits are ephemeral, they cannot comprise a permanent microbial habitat; thus, an age-old unanswered question concerns the origin of fruit and ferment associated microbes. Here we use next-generation sequencing approaches to examine and quantify the roles of native forests, vineyard soil, bark, and fruit habitats as sources of fungal diversity in ferments...
October 20, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/29051441/the-food-and-beverage-occurrence-of-furfuryl-alcohol-and-myrcene-two-emerging-potential-human-carcinogens
#13
Alex O Okaru, Dirk W Lachenmeier
For decades, compounds present in foods and beverages have been implicated in the etiology of human cancers. The World Health Organization (WHO) International Agency for Research on Cancer (IARC) continues to classify such agents regarding their potential carcinogenicity in humans based on new evidence from animal and human studies. Furfuryl alcohol and β-myrcene are potential human carcinogens due to be evaluated. The major source of furfuryl alcohol in foods is thermal processing and ageing of alcoholic beverages, while β-myrcene occurs naturally as a constituent of the essential oils of plants such as hops, lemongrass, and derived products...
March 11, 2017: Toxics
https://www.readbyqxmd.com/read/29051433/a-review-of-heavy-metal-concentration-and-potential-health-implications-of-beverages-consumed-in-nigeria
#14
REVIEW
Sylvester Chibueze Izah, Iniobong Reuben Inyang, Tariwari C N Angaye, Ifeoma Peace Okowa
Beverages are consumed in Nigeria irrespective of age, sex, and socioeconomic status. Beverages may be alcoholic (wine, spirits, and beers) or non-alcoholic (soft drink, energy drinks, candies, chocolates, milks). Notwithstanding, most beverages are packed in cans, bottles, and plastics. This paper reviews the concentration of heavy metals from some commercially-packaged beverages consumed in Nigeria. The study found that heavy metal concentrations, including iron, mercury, tin, antimony, cadmium, zinc, copper, chromium, lead, and manganese, seldom exceed the maximum contaminant level recommended by the Standard Organization of Nigeria (SON) and the World Health Organization (WHO) as applicable to drinking water resources...
December 22, 2016: Toxics
https://www.readbyqxmd.com/read/29050188/-sturge-weber-syndrome-in-port-wine-stain-patients-a-retrospective-study-on-the-clinical-features-and-screening-strategy
#15
Y Wu, R J Yu, X X Lin, W Y Guo
Objective: To investigate the clinical characteristics of Sturge-Weber syndrome (SWS) in the patients with Port-wine stain (PWS). Methods: A total of 279 PWS patients, 164 males, 115 females with a median age of first visit 17.00 (4.75, 56.00) months. Most of the PWS patients were referred to the Ophthalmology Department for screening eye problems when the cutaneous angiomas involved the ophthalmic division of the trigeminal nerve distribution. The intraocular pressure (IOP), cup to disk ratio (C/D), corneal condition and other essential measurements were examined to screen glaucoma or choroidal hemangioma...
October 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29032226/maternal-depressive-symptoms-linked-to-reduced-fecal-immunoglobulin-a-concentrations-in-infants
#16
Liane J Kang, Petya T Koleva, Catherine J Field, Gerald F Giesbrecht, Eytan Wine, Allan B Becker, Piushkumar J Mandhane, Stuart E Turvey, Padmaja Subbarao, Malcolm R Sears, James A Scott, Anita L Kozyrskyj
Secretory Immunoglobulin A (sIgA) plays a critical role to infant gut mucosal immunity. Delayed IgA production is associated with greater risk of allergic disease. Murine models of stressful events during pregnancy and infancy show alterations in gut immunity and microbial composition in offspring, but little is known about the stress-microbiome-immunity pathways in humans. We investigated differences in infant fecal sIgA concentrations according to the presence of maternal depressive symptoms during and after pregnancy...
October 12, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29032141/moderate-alcohol-consumption-is%C3%A2-associated-with-lower-risk-for-heart%C3%A2-failure-but-not-atrial-fibrillation
#17
Augusto Di Castelnuovo, Simona Costanzo, Marialaura Bonaccio, Livia Rago, Amalia De Curtis, Mariarosaria Persichillo, Francesca Bracone, Marco Olivieri, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello
OBJECTIVES: The aim of this study was to assess the hypothesis that alcohol consumption is associated with onset of atrial fibrillation (AF) and/or heart failure (HF). BACKGROUND: The connection between ethanol intake and AF or HF remains controversial. METHODS: The study population was 22,824 AF- or HF-free subjects (48% men, age ≥35 years) randomly recruited from the general population included in the Moli-sani study, for whom complete data on HF, AF, and alcohol consumption were available...
November 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/29029940/antibody-dependent-phagocytosis-adp-responses-following-trivalent-inactivated-influenza-vaccination-of-younger-and-older-adults
#18
Fernanda Ana-Sosa-Batiz, Angus P R Johnston, P Mark Hogarth, Bruce D Wines, Ian Barr, Adam K Wheatley, Stephen J Kent
Globally the most commonly utilised immunisation against influenza is the trivalent inactivated influenza vaccine (TIV) derived from an A/H1N1, an A/H3N2 and aB type influenza virus. Vaccine effectiveness of TIV varies year to year, depending on how well antigenically matched the strains in the vaccine are compared to circulating strains [1,2]. Moreover, vaccine effectiveness can vary within certain subpopulations such as HIV-positive, young children and the elderly. Decreased vaccine effectiveness in the elderly is associated with impaired Ab production, as measured by standard hemagglutination inhibition (HAI) assays...
November 7, 2017: Vaccine
https://www.readbyqxmd.com/read/29022677/alcohol-consumption-in-population-aged-25-65-years-living-in-the-metropolis-of-south-moravia-czech-republic
#19
Jindřich Fiala, Ondřej Sochor, Helena Klimusová, Martin Homolka
OBJECTIVE: The aim of the study was to evaluate alcohol consumption in a representative sample of the population of the city of Brno, as part of research on cardiovascular risk factors. METHODS: Cross-sectional survey on a sample of 2,160 randomly selected residents 35-65 years old was carried out. For the invited volunteers who became a part of the investigation, alcohol consumption was determined in a controlled, face to face interview structured in accordance with a special questionnaire form...
September 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28994643/shorter-treatment-intervals-of-east-asians-with-port-wine-stain-with-pulsed-dye-laser-are-safe-and-effective-a-prospective-side-by-side-comparison
#20
Wenxin Yu, Jiafang Zhu, Shih-Jen Changc, Hui Chen, Yunbo Jin, Xi Yang, Tianyou Wang, Lei Chang, Yijie Chen, Gang Ma, Xiaoxi Lin
OBJECTIVE: To compare the safety and efficacy of pulsed dye laser (PDL) at different intervals for the treatment of East Asians with Port-Wine Stain (PWS). BACKGROUND: The population of East Asians around the world is about 1.6 billion, and they are considered to have more melanin in their skin compared with Caucasians. Nevertheless, no studies about the optimal treatment intervals for East Asians with PWS have been carried out. METHODS: We prospectively investigated 39 East Asian patients with untreated PWS...
October 10, 2017: Photomedicine and Laser Surgery
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