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Wine and ageing

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https://www.readbyqxmd.com/read/27916747/the-broadly-tuned-odorant-receptor-or1a1-is-highly-selective-for-3-methyl-2-4-nonanedione-a-key-food-odorant-in-aged-wines-tea-and-other-foods
#1
Christiane Geithe, Franziska Noe, Johanna Kreissl, Dietmar Krautwurst
Key food odorants are the most relevant determinants by which we detect, recognize, and hedonically evaluate the aroma of foods and beverages. Odorants are detected by our chemical sense of olfaction, comprising a set of approximately 400 different odorant receptor types. However, the specific receptor activity patterns representing the aroma percepts of foods or beverages, as well as the key food odorant agonist profiles of single-odorant receptors, are largely unknown. We aimed to establish comprehensive key food odorant agonist profiles of 2 unrelated, broadly tuned receptors, OR1A1 and OR2W1, that had been associated thus far with mostly non-key food odorants and shared some of these agonists...
December 4, 2016: Chemical Senses
https://www.readbyqxmd.com/read/27901083/resveratrol-serves-as-a-protein-substrate-interaction-stabilizer-in-human-sirt1-activation
#2
Xuben Hou, David Rooklin, Hao Fang, Yingkai Zhang
Resveratrol is a natural compound found in red wine that has been suggested to exert its potential health benefit through the activation of SIRT1, a crucial member of the mammalian NAD(+)-dependent deacetylases. SIRT1 has emerged as an attractive therapeutic target for many aging related diseases, however, how its activity can only be activated toward some specific substrates by resveratrol has been poorly understood. Herein, by employing extensive molecular dynamics simulations as well as fragment-centric topographical mapping of binding interfaces, we have clarified current controversies in the literature and elucidated that resveratrol plays an important activation role by stabilizing SIRT1/peptide interactions in a substrate-specific manner...
November 30, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27887699/an-improved-method-for-the-analysis-of-2-aminoacetophenone-in-wine-based-on-headspace-solid-phase-microextraction-and-heart-cut-multidimensional-gas-chromatography-with-selective-detection-by-tandem-mass-spectrometry
#3
Hans-Georg Schmarr, Jutta Keiser, Susann Krautwald
Heart-cut multidimensional gas chromatography coupled to selective mass spectrometric detection (H/C MDGC-MS-MS) was shown to be a suitable combination for analysis of the key component for the wine off-flavor named "atypical aging off-flavor" (german: "Untypische Alterungsnote", UTA), 2-aminoacetophenone (2-AAP). Headspace solid phase microextraction (HS-SPME) was applied as an easy to automate sample preparation step suiting routine control situations. During method development two critical aspects were found, of which one is the chemical degradation of the neat substance, leading to signal reduction and a false response behavior...
November 20, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27884595/melatonin-protection-against-age-related-cardiac-pathology
#4
REVIEW
Gaia Favero, Lorenzo Franceschetti, Barbara Buffoli, Moghadasian H Mohammed, Russel J Reiter, Luigi Fabrizio Rodella, Rita Rezzani
Aging is a complex and progressive process that involves physiological and metabolic deterioration in every organ and system. Cardiovascular diseases are one of the most common causes of mortality and morbidity among elderly subjects worldwide. Most age-related cardiovascular disorders can be influenced by modifiable behaviours such as a healthy diet rich in fruit and vegetables, avoidance of smoking, increased physical activity and reduced stress. The role of diet in prevention of various disorders is a well-established factor, which has an even more important role in the geriatric population...
November 21, 2016: Ageing Research Reviews
https://www.readbyqxmd.com/read/27866465/polyphenol-rich-foods-alleviate-pain-and-ameliorate-quality-of-life-in-fibromyalgic-women
#5
Renata Costa de Miranda, Eduardo S Paiva, Silvia Maria Suter Correia Cadena, Anna Paula Brandt, Regina Maria Vilela
OBJECTIVES: The present study aimed to describe the antioxidant dietary intake of patients with fibromyalgia and explore the association of the results with glutathione status, pain, quality of life, and socioeconomic status. METHODS: 38 fibromyalgic female patients and 35 female controls (mean age = 48.6 ± 8.1 and 47.6 ± 10.0 years, respectively) were evaluated. The number of tender points, pain threshold, quality of life, physical activity, socioeconomic status, nutritional status, intake of antioxidant micronutrients and foods with high total antioxidant capacity, and total salivary glutathione were evaluated...
November 21, 2016: International Journal for Vitamin and Nutrition Research. Journal International de Vitaminologie et de Nutrition
https://www.readbyqxmd.com/read/27861761/prediagnostic-alcohol-consumption-and-colorectal-cancer-survival-the-colon-cancer-family-registry
#6
Amanda I Phipps, Jamaica R Robinson, Peter T Campbell, Aung Ko Win, Jane C Figueiredo, Noralane M Lindor, Polly A Newcomb
BACKGROUND: Although previous studies have noted an increased risk of colorectal cancer (CRC) among moderate to heavy alcohol consumers in comparison with nondrinkers, the relation between alcohol consumption and CRC survival remains unclear. METHODS: Cases of incident invasive CRC diagnosed between 1997 and 2007 were identified via population-based cancer registries at 4 study sites in the Colon Cancer Family Registry. Study participants completed a risk-factor questionnaire on prediagnostic behaviors, including wine, beer, and liquor consumption, at the baseline...
November 8, 2016: Cancer
https://www.readbyqxmd.com/read/27856335/examining-the-impact-of-grape-consumption-on-brain-metabolism-and-cognitive-function-in-patients-with-mild-decline-in-cognition-adouble-blinded-placebo-controlled-pilot-study
#7
Jooyeon Lee, Nare Torosyan, Daniel H Silverman
BACKGROUND: Natural compounds in grapes such as resveratrol are known for their antioxidant and anti-inflammatory properties. Some studies have shown a potential role for grapes or wine in slowing cognitive decline and other effects of aging. However, well-controlled experimental data obtained in human subjects are still in need of further development. Here we aimed to systemically assess effects of grapes on regional cerebral metabolism. METHODS: Ten subjects with mild decline in cognition (mean, 72...
November 14, 2016: Experimental Gerontology
https://www.readbyqxmd.com/read/27855930/unexpected-impact-of-2-methylisoborneol-as-off-odour-substance-in-aged-wines
#8
Angela Lopez Pinar, Rahil Ghadiriasli, Philippe Darriet, Andrea Buettner
Four Pinot noir wines from Burgundy were investigated by gas chromatography-olfactometry, with regard to the presence of earthy-smelling compounds. 2-Methylisoborneol (2-MIB) was detected in two of these wines, although the samples were seven years old, contradicting previous reports that this substance is unstable in wine and must. In order to investigate this seemingly paradoxical situation, 2-MIB stability was reinvestigated in wine and in model solution starting with an elevated initial concentration. Although 2-MIB concentration greatly decreased during the 90days of storage, the final concentration measured in both media was well above the odour threshold of the substance...
April 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27826547/electronic-noses-and-tongues-in-wine-industry
#9
REVIEW
María L Rodríguez-Méndez, José A De Saja, Rocio González-Antón, Celia García-Hernández, Cristina Medina-Plaza, Cristina García-Cabezón, Fernando Martín-Pedrosa
The quality of wines is usually evaluated by a sensory panel formed of trained experts or traditional chemical analysis. Over the last few decades, electronic noses (e-noses) and electronic tongues have been developed to determine the quality of foods and beverages. They consist of arrays of sensors with cross-sensitivity, combined with pattern recognition software, which provide a fingerprint of the samples that can be used to discriminate or classify the samples. This holistic approach is inspired by the method used in mammals to recognize food through their senses...
2016: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/27824864/a-prospective-study-of-alcohol-consumption-and-smoking-and-the-risk-of-major-gastrointestinal-bleeding-in-men
#10
Lisa L Strate, Prashant Singh, Matthew R Boylan, Sorbarikor Piawah, Yin Cao, Andrew T Chan
BACKGROUND AND AIMS: Data regarding smoking and alcohol consumption and risk of gastrointestinal bleeding (GIB) are sparse and conflicting. We assessed the risk of major GIB associated with smoking and alcohol consumption in a large, prospective cohort. METHODS: We prospectively studied 48,000 men in the Health Professional follow-up Study (HPFS) who were aged 40-75 years at baseline in 1986. We identified men with major GIB requiring hospitalization and/or blood transfusion via biennial questionnaires and chart review...
2016: PloS One
https://www.readbyqxmd.com/read/27811119/alcohol-consumption-and-the-risk-of-colorectal-cancer-in-mismatch-repair-gene-mutation-carriers
#11
S Ghazaleh Dashti, Daniel D Buchanan, Harindra Jayasekara, Driss Ait Ouakrim, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Finlay A Macrae, Graham G Giles, Susan Parry, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, Mark A Jenkins, Aung Ko Win
Background People with germline mutation in one of the DNA mismatch repair (MMR) genes have increased colorectal cancer risk. For these high-risk people, study findings of the relationship between alcohol consumption and colorectal cancer risk have been inconclusive. Methods 1,925 MMR gene mutations carriers recruited into the Colon Cancer Family Registry who had completed a questionnaire on lifestyle factors were included. Weighted Cox proportional hazard regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between alcohol consumption and colorectal cancer...
November 3, 2016: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/27809234/the-effects-of-pre-fermentative-addition-of-oenological-tannins-on-wine-components-and-sensorial-qualities-of-red-wine
#12
Kai Chen, Carlos Escott, Iris Loira, Juan Manuel Del Fresno, Antonio Morata, Wendu Tesfaye, Fernando Calderon, Santiago Benito, Jose Antonio Suárez-Lepe
Today in the wine industry, oenological tannins are widely used to improve wine quality and prevent oxidation in wine aging. With the development of tannin products, new oenological tannins are developed with many specific functions, such as modifying antioxidant effect, colour stabilization and aroma modifications. The aim of this work is to investigate effects of pre-fermentative addition of oenological tannins on wine colour, anthocyanins, volatile compounds and sensorial properties. In this case, Syrah juice was extracted with classic flash thermovinification from fresh must in order to release more colour and tannins...
October 31, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27801796/portable-electronic-tongue-based-on-microsensors-for-the-analysis-of-cava-wines
#13
Pablo Giménez-Gómez, Roger Escudé-Pujol, Fina Capdevila, Anna Puig-Pujol, Cecilia Jiménez-Jorquera, Manuel Gutiérrez-Capitán
Cava is a quality sparkling wine produced in Spain. As a product with a designation of origin, Cava wine has to meet certain quality requirements throughout its production process; therefore, the analysis of several parameters is of great interest. In this work, a portable electronic tongue for the analysis of Cava wine is described. The system is comprised of compact and low-power-consumption electronic equipment and an array of microsensors formed by six ion-selective field effect transistors sensitive to pH, Na⁺, K⁺, Ca(2+), Cl(-), and CO₃(2-), one conductivity sensor, one redox potential sensor, and two amperometric gold microelectrodes...
October 27, 2016: Sensors
https://www.readbyqxmd.com/read/27784325/alcohol-consumption-and-accentuated-personality-traits-among-young-adults-in-romania-a-cross-sectional-study
#14
Cornelia Rada, Alexandru Teodor Ispas
BACKGROUND: Alcohol consumption (AC) has negative social and economic consequences, affects health, and can create dependence. As dependence is particularly difficult to cure, prevention is important. This study aimed to identify the frequency, quantity, occasions, reasons, type of AC, and correlation with accentuated personality traits among young adults in Romania. METHODS: Participants were 1359 young adults aged 18-30 years (average age, 22.67 years; standard deviation [SD], 3...
October 27, 2016: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/27755647/effect-of-oak-chips-on-evolution-of-phenolic-compounds-and-color-attributes-of-bog-bilberry-syrup-wine-during-bottle-aging
#15
Shuxun Liu, Shaoyang Wang, Guanshen Yuan, Xiaoyu Ouyang, Yaran Liu, Baoqing Zhu, Bolin Zhang
This study investigated the evolution of phenolic compounds of bog bilberry syrup wine during a bottle-aging process, and further estimated the oak chip treatment on the wine color alteration. The wine was macerated with oak chips (2 or 5 g/L under light or medium toasting level) for 20 d and then bottle-aged for 6 mo. Results showed that the oak chip treatment significantly increased the content of phenolic compounds and enhanced the copigmented anthocyanin level before aging. It also resulted in an increase on a(*) and C(*) but a decrease on L(*) , b(*) , and H(*) of the wine...
October 18, 2016: Journal of Food Science
https://www.readbyqxmd.com/read/27717288/the-influence-of-chirality-of-lactones-on-the-perception-of-some-typical-fruity-notes-through-perceptual-interaction-phenomena-in-bordeaux-dessert-wines
#16
Panagiotis Stamatopoulos, Eric Brohan, Celine Prevost, Tracey Ellen Siebert, Markus J Herderich, Philippe Darriet
Recent studies concerning the aroma of noble rot dessert wines revealed the importance of a well-known phenomenon in perfumery, the perceptual blending, to create the perception of 'overripe orange' nuances. Thus, compounds associated with both oak wood aging (3-methyl-4-octanolide, eugenol) and Botrytis cinerea development under the form of noble rot (2-nonen-4-olide, γ-nonalactone) are contributing to a specific aroma of great noble rot dessert wines through perceptual interaction phenomena. This synthetic perception phenomenon was established from reconstitution, addition and omission sensory experiments, using wine extracts fractions supplemented with the volatile compounds previously mentioned...
October 7, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27714637/headaches-a-review-of-the-role-of-dietary-factors
#17
Zoya Zaeem, Lily Zhou, Esma Dilli
Dietary triggers are commonly reported by patients with a variety of headaches, particularly those with migraines. The presence of any specific dietary trigger in migraine patients varies from 10 to 64 % depending on study population and methodology. Some foods trigger headache within an hour while others develop within 12 h post ingestion. Alcohol (especially red wine and beer), chocolate, caffeine, dairy products such as aged cheese, food preservatives with nitrates and nitrites, monosodium glutamate (MSG), and artificial sweeteners such as aspartame have all been studied as migraine triggers in the past...
November 2016: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/27705842/beverage-specific-patterns-of-5-alcoholic-drink-consumption-by-young-adults-in-the-u-s
#18
Stephanie A Stern, Yvonne M Terry-McElrath, Megan E Patrick
Young adult binge drinking prevalence has been widely researched. However, beverage-specific binge drinking rates for beer, liquor, wine, and wine coolers have not yet been documented for this age group. This study examines consumption of specific beverages (i.e., 5+ drinks in a row in the past two weeks) by young adults aged 19/20. Data from the national Monitoring the Future study were collected one or two years after high school from 2004 to 2014 (n=2004). Logistic regression was used to examine associations between beverage-specific 5+ drinking and gender, race/ethnicity, parent education, college status, and cohort year...
February 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/27689433/piperitone-profiling-in-fine-red-bordeaux-wines-geographical-influences-in-the-bordeaux-region-and-enantiomeric-distribution
#19
Magali Picard, Sophie Tempere, Gilles de Revel, Stéphanie Marchand
Piperitone was recently identified in red Bordeaux wines, and this study was designed to further explore its contribution to wine aroma. Firstly, a geographical origin effect was detected within the Bordeaux region (left versus right banks of the Gironde estuary), with significantly higher mint aroma intensities and piperitone levels in wines from the left bank (Medoc appellations). Statistical analysis of chemical and sensory data highlighted a correlation with the proportion of Cabernet Sauvignon in the wine blends...
October 12, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27684096/taste-guided-isolation-of-bitter-lignans-from-quercus-petraea-and-their-identification-in-wine
#20
Lauriane Sindt, Marine Gammacurta, Pierre Waffo-Teguo, Denis Dubourdieu, Axel Marchal
Quercoresinosides A and B (1 and 2), two new lignans, were isolated from a toasted Quercus petraea heartwood extract along with a known compound, 3-methoxy-4-hydroxyphenol 1-O-β-d-(6'-O-galloyl)glucopyranoside (3). The purification protocol was based on a taste-guided approach that sought to reveal new bitter compounds released from oak wood into wines and spirits. HRMS and NMR data were used to establish that compounds 1 and 2 are lignan derivatives bearing a glucosyl unit and a galloyl unit at the same positions...
September 29, 2016: Journal of Natural Products
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