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https://www.readbyqxmd.com/read/29334558/comment-on-a-propensity-score-matched-analysis-of-open-versus-minimally-invasive-transthoracic-esophagectomy-in-the-netherlands
#1
Miguel A Cuesta, Jennifer Straatman, Donald L van der Peet
No abstract text is available yet for this article.
January 12, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29334555/multi-institutional-analysis-of-recurrence-and-survival-after-neoadjuvant-chemoradiotherapy-of-esophageal-cancer-impact-of-histology-on-recurrence-patterns-and-outcomes
#2
Mian Xi, Yadi Yang, Li Zhang, Hong Yang, Kenneth W Merrell, Christopher L Hallemeier, Robert K Shen, Michael G Haddock, Wayne L Hofstetter, Dipen M Maru, Linus Ho, Carol C Wu, Mengzhong Liu, Steven H Lin
OBJECTIVE: To determine the impact of histology on pathologic response, survival outcomes, and recurrence patterns in patients with esophageal cancer (EC) who received neoadjuvant chemoradiotherapy (CRT). SUMMARY OF BACKGROUND DATA: There is a paucity of data regarding comparative outcomes after neoadjuvant CRT between esophageal squamous cell carcinoma (SCC) and adenocarcinoma. METHODS: Between 2002 and 2015, 895 EC patients who underwent neoadjuvant CRT followed by esophagectomy at 3 academic institutions were retrospectively reviewed, including 207 patients with SCC (23...
January 12, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29332350/short-and-long-term-outcomes-of-minimally-invasive-esophagectomy-in-elderly-patients-with-esophageal-squamous-cell-carcinoma
#3
H Zhao, Gang Liu, S Wei, H Liu
PURPOSE: In recent years, there has been an increase in the number of elderly patients undergoing surgery for esophageal squamous cell carcinoma (ESCC). However, there are few studies on short- and long-term outcomes of minimally invasive esophagectomy (MIE) in such patients. The purpose of this study was to report both short- and long-term outcomes of MIE in elderly patients with ESCC. METHODS: A total of 273 patients with ESCC underwent MIE at our hospital from January 2010 to December 2016...
November 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29332233/pilot-study-of-serial-flt-and-fdg-pet-ct-imaging-to-monitor-response-to-neoadjuvant-chemoradiotherapy-of-esophageal-adenocarcinoma-correlation-with-histopathologic-response
#4
Victor H Gerbaudo, Joseph H Killoran, Chun K Kim, Jason L Hornick, Jonathan A Nowak, Peter C Enzinger, Harvey J Mamon
OBJECTIVE: The aim of this prospective pilot study was to investigate the potential of serial FLT-PET/CT compared to FDG-PET/CT to provide an early indication of esophageal cancer response to concurrent neoadjuvant chemoradiation therapy. METHODS: Five patients with biopsy-proven esophageal adenocarcinomas underwent neoadjuvant chemoradiation (Tx) prior to minimally invasive esophagectomy. The presence of residual tumor was classified histologically using the Mandard et al...
January 13, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29329479/individual-endoscopic-management-of-anastomotic-insufficiency-after-esophagectomy-for-esophageal-squamous-cell-carcinoma-and-creation-of-a-neostomach
#5
Edris Wedi, Philipp Schüler, Steffen Kunsch, B Micheal Ghadimi, Ali Seif Amir Hosseini, Volker Ellenrieder, Carlo Jung
No abstract text is available yet for this article.
January 12, 2018: Endoscopy
https://www.readbyqxmd.com/read/29319236/neoadjuvant-chemotherapy-followed-by-minimally-invasive-esophagectomy-is-safe-and-feasible-for-treatment-of-esophageal-squamous-cell-carcinoma
#6
Shaohua Ma, Tiansheng Yan, Dandan Liu, Keyi Wang, Jingdi Wang, Jintao Song, Tong Wang, Wei He, Jie Bai, Liang Jin, Xiaoxin Chen
BACKGROUND: The advantage of neoadjuvant chemotherapy (NAC) followed by open esophagectomy for treatment of esophageal squamous cell carcinoma has been widely recognized. However, the safety and feasibility of NAC for patients receiving minimally invasive esophagectomy (MIE) remain controversial. The purpose of this study was to evaluate the potential impact of prior neoadjuvant chemotherapy on the clinical outcome of MIE by comparing two groups of patients, MIE alone and NAC plus MIE...
January 10, 2018: Thoracic Cancer
https://www.readbyqxmd.com/read/29318416/air-bubble-sign-a-new-screening-method-for-anastomotic-leakage-after-esophagectomy-for-esophageal-cancer
#7
Yoshiaki Shoji, Hiroya Takeuchi, Kazumasa Fukuda, Rieko Nakamura, Norihito Wada, Hirofumi Kawakubo, Yuko Kitagawa
BACKGROUND: Contrast esophagography often is performed to screen for anastomotic leakage (AL) after esophagectomy. However, its sensitivity remains low. Adverse events also have been reported. This report describes a new screening method to detect AL on computed tomography (CT) after esophagectomy. METHODS: From January 2012 to December 2015, 185 patients with esophageal cancer underwent surgical resection at the authors' institution. The study comparatively reviewed patient characteristics, surgical outcomes, and findings from postoperative CT images and contrast esophagrams of 142 patients who underwent esophagectomy followed by primary gastric conduit reconstruction through a posterior mediastinum route...
January 9, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29313724/early-enteral-nutrition-is-associated-with-faster-post-esophagectomy-recovery-in-chinese-esophageal-cancer-patients-a-retrospective-cohort-study
#8
Hongyu Han, Meixia Pan, Yang Tao, Runzhong Liu, Zhiliang Huang, Korinne Piccolo, Caiyun Zhong, Ranyi Liu
We retrospectively examined a large cohort of esophageal carcinoma patients who received early enteral nutrition (EEN) to clarify the validity of EEN compared with total parenteral nutrition (TPN). Included were a total of 665 consecutive patients with histologically confirmed carcinoma of the esophagus or esophagogastric junction; and all patients underwent esophagectomy. The patients were divided into two groups: TPN (n = 262) and EEN (n = 403). The TPN group consisted of patients who only received intravenous nutrition support after operation...
January 9, 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/29312733/longitudinal-study-of-esophageal-mucosal-damage-after-esophagectomy-and-gastric-interposition-relationship-between-reflux-related-mucosal-injury-and-notch-signaling
#9
Yong Yuan, Tie-Jun Tong, Xiao-Xi Zeng, Yu-Shang Yang, Zhi-Qiang Wang, Yun-Cang Wang, Jun-He Gou, Long-Qi Chen
Background: Esophagectomy with gastric interposition could serve as a good human reflux model to study the molecular pathogenesis of esophageal mucosal damage induced by gastroesophageal reflux. This study was to investigate the role of Notch signaling in reflux injury of esophageal mucosa. Methods: Patients undergoing Ivor-Lewis esophagectomy for early stage esophageal squamous cell carcinoma were included. Follow-ups were scheduled at 6, 18, 36 and 48 months postoperatively, including reflux symptom assessment, endoscopic and histological evaluation of esophageal mucosal damage...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29312728/feasibility-and-outcomes-of-modified-enhanced-recovery-after-surgery-for-nursing-management-of-aged-patients-undergoing-esophagectomy
#10
Wei Li, Bin Zheng, Shuliang Zhang, Hao Chen, Wei Zheng, Chun Chen
Background: The aim of this study was to determine whether a modified enhanced recovery after surgery (mERAS) protocol has a positive effect on the recovery of aged patients with esophageal cancer undergoing esophagectomy. Methods: Consecutive patients were selected between January 2015 and June 2016 and were randomly assigned to a control group (traditional nursing care) or an observation group (mERAS protocol). We analyzed the outcomes of the patients, including surgical outcomes, postoperative complications, mental health status, and quality of life (QOL)...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29312708/substernal-reconstruction-following-esophagectomy-operation-of-last-resort
#11
Jacob R Moremen, DuyKhanh P Ceppa, Karen M Rieger, Thomas J Birdas
Background: The posterior mediastinum is the preferred location for reconstruction following esophagectomy. Occasionally alternative routes are required. We examined patient outcomes of esophageal reconstruction in order to determine whether substernal reconstruction (SR) is an equivalent alternative to orthotopic placement. Methods: Following IRB approval, we performed a retrospective review of all patients who underwent an esophagectomy from 1988-2014. Only patients reconstructed with a gastric conduit and cervical anastomosis by either substernal or posterior mediastinal (PM) routes were included in the study...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29312700/modified-exposure-method-for-gastric-mobilization-in-robot-assisted-esophagectomy
#12
Yu Zheng, Xi-Wen Zhao, Han-Lu Zhang, Zi-Hao Wang, Yun Wang
Background: We describe a modified method to facilitate gastric mobilization in robotic esophagectomy. Furthermore, we performed a prospective comparative analysis of surgical outcomes between the conventional method and described technique. Methods: From April 1st, 2016 to December 31st, 2016, 59 consecutive patients were included who underwent robot-assisted McKeown esophagectomy for esophageal squamous cell carcinoma in our institution. They were subdivided into two groups based on the method of gastric exposure: a grasper retraction (GR) group (n=27) and a thread retraction (TR) group (n=32)...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29310892/sarcopenia-is-not-associated-with-morbidity-mortality-or-recurrence-after-esophagectomy-for-cancer
#13
Steve R Siegal, James P Dolan, Elizabeth N Dewey, Alexander R Guimaraes, Brandon H Tieu, Paul H Schipper, John G Hunter
BACKGROUND: Sarcopenia is associated with increased morbidity and mortality in hepatic, pancreatic and colorectal cancer. We examined the effect of sarcopenia on morbidity, mortality, and recurrence after resection for esophageal cancer. METHODS: Retrospective review of consecutive esophagectomies from 2010 to 2015. Computed tomography studies were analyzed for sarcopenia. Morbidity was analyzed using Fischer's test and survival data with Kaplan Meier curves. RESULTS: The sarcopenic group (n = 127) had lower BMI, later stage disease, and higher incidence of neoadjuvant radiation than those without sarcopenia (n = 46)...
January 4, 2018: American Journal of Surgery
https://www.readbyqxmd.com/read/29310400/clinical-analysis-of-hyperkalemia-after-esophagectomy-a-case-report
#14
Qiang Chen, Wei-Guo Zhang, Shu-Chang Chen
RATIONALE: The occurrence of hyperkalemia after esophagectomy is clinically rare. Patients who underwent esophagectomy often have a serum potassium level due to perioperative reduced intake, fluids loss, consumption and other reasons. These patients often require the artificial administration of potassium. Rapid fluid loss and physiological consumption lead to the deficiency of potassium, even hypokalemia. Patients often require the addition of a large amount of potassium after operation...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29308064/effectiveness-of-etilefrine-regimen-for-chylothorax-after-esophagectomy-with-thoracic-duct-resection
#15
Yu Ohkura, Masaki Ueno, Toshiro Iizuka, Harushi Udagawa
Background: Management of postoperative chylothorax generally involves nutritional regimens as well as pharmacological and surgical therapies, but a clear consensus has yet to be reached. Methods: Retrospective review of 371 patients who underwent esophagectomy for esophageal cancer was performed. They were patients with squamous cell carcinoma or adenocarcinoma of the esophagus including Siewert type I/II tumor of the esophagogastric junction who underwent subtotal esophagectomy...
2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/29307454/increased-variance-in-oral-and-gastric-microbiome-correlates-with-esophagectomy-anastomotic-leak
#16
Rishindra M Reddy, William B Weir, Shari Barnett, Brendan T Heiden, Mark B Orringer, Jules Lin, Andrew C Chang, Philip W Carrott, William R Lynch, David G Beer, J Christopher Fenno, Yvonne Kapila
BACKGROUND: Anastomotic leak after esophagectomy remains a significant source of morbidity and mortality. The gastrointestinal (GI) microbiome has been found to play a significant role in tumor oncogenesis and postoperative bowel anastomotic leak. We hypothesized that the GI microbiome could differentiate between esophageal cancer histologies and predict postoperative anastomotic leak. METHODS: A prospective study of esophagectomy patients was performed from May 2013 to August 2014, with the collection of oral saliva, intraoperative esophageal and gastric mucosa, and samples of postoperative infections (neck swab or sputum)...
January 4, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29303804/response-a-propensity-score-matched-analysis-of-open-versus-minimally-invasive-transthoracic-esophagectomy-in-the-netherlands
#17
Maarten F J Seesing, Bas P L Wijnhoven
No abstract text is available yet for this article.
January 4, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29302639/minimally-invasive-esophagectomy-via-sweet-approach-in-combination-with-cervical-mediastinoscopy-for-esophageal-squamous-cell-carcinoma-a-case-series
#18
Wenxiang Wang, Baihua Zhang, Xu Li, Jie Wu, Zhining Wu, Yan Ding, Desong Yang, Jinming Tang, Min Su, Junliang Ma, Xianman You, Jianping Liang, Yong Zhou
Objective: Minimally invasive esophagectomy (MIE) is increasingly used for the treatment of esophageal cancer. However, MIE via the Sweet approach has seldom been reported owing to the challenging procedure for a mediastinal lymph node. Thus, the approach of MIE via left-sided thoracoscopy coupled with video-assisted cervical mediastinoscopy (MIE-SM) was explored for eradicating the mediastinal lymph nodes and recurrent laryngeal nerve; the incidence of perioperative complications, mortality, and surgical radicality were analyzed...
December 2017: International Journal of Surgery. Oncology
https://www.readbyqxmd.com/read/29299354/post-operative-radiotherapy-is-associated-with-improved-survival-in-esophageal-cancer-with-positive-surgical-margins
#19
Sarah J Gao, Henry S Park, Christopher D Corso, Charles E Rutter, Sajid A Khan, Kimberly L Johung
Background: The optimal treatment for early-stage esophageal cancer with positive surgical margins after an upfront esophagectomy is not well-defined. This study investigates the effect of post-operative radiotherapy (PORT) on overall survival (OS) in clinical stage I-II patients with positive margins. Methods: We identified patients diagnosed between 2004 and 2012 with clinical stage I-II esophageal carcinoma from the National Cancer Data Base (NCDB) who underwent an upfront esophagectomy...
December 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29290655/endoscopic-ultrasound-staging-for-early-esophageal-cancer-are-we-denying-patients-neoadjuvant-chemo-radiation
#20
Carrie Luu, Marisa Amaral, Jason Klapman, Cynthia Harris, Khaldoun Almhanna, Sarah Hoffe, Jessica Frakes, Jose M Pimiento, Jacques P Fontaine
AIM: To evaluate the accuracy of endoscopic ultrasound (EUS) in early esophageal cancer (EC) performed in a high-volume tertiary cancer center. METHODS: A retrospective review of patients undergoing esophagectomy was performed and patients with cT1N0 and cT2N0 esophageal cancer by EUS were evaluated. Patient demographics, tumor characteristics, and treatment were reviewed. EUS staging was compared to surgical pathology to determine accuracy of EUS. Descriptive statistics was used to describe the cohort...
December 14, 2017: World Journal of Gastroenterology: WJG
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