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https://www.readbyqxmd.com/read/29352683/discharge-to-inpatient-rehab-does-not-result-in-improved-functional-outcomes-following-primary-total-knee-arthroplasty
#1
Douglas E Padgett, Alexander B Christ, Amethia D Joseph, You-Yu Lee, Stephen B Haas, Stephen Lyman
BACKGROUND: Monitored rehabilitation has long been considered an essential part of the recovery process in total knee arthroplasty (TKA). However, the optimal setting for rehabilitation remains uncertain. We sought to determine whether inpatient rehabilitation settings result in improved functional and patient-reported outcomes after primary TKA. METHODS: All patients undergoing primary TKA from May 2007 to February 2011 were identified from our institutional total joint registry...
December 28, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29352659/microwave-ablation-provides-better-survival-than-liver-resection-for-hepatocellular-carcinoma-in-patients-with-borderline-liver-function-application-of-albi-score-to-patient-selection
#2
Charing C N Chong, Kit-Fai Lee, Cheuk-Man Chu, Anthony W H Chan, John Wong, Stephen L Chan, Hon-Ting Lok, Andrew K Y Fung, Anthony K W Fong, Yue S Cheung, Simon C H Yu, Philip Johnson, Paul B S Lai
BACKGROUND: Studies comparing microwave ablation (MWA) and liver resection are lacking. This study evaluates the survival of patients with hepatocellular carcinoma (HCC) treated with liver resection or MWA and the role of Albumin-Bilirubin (ALBI) score in patient selection for treatments. METHODS: This is a retrospective analysis of patients who received curative liver resection or MWA for HCC. Propensity score matching was used at a 1:1 ratio. The value of ALBI grade for patient selection was evaluated...
January 15, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29352566/in-hospital-cerebrovascular-outcomes-of-patients-with-atrial-fibrillation-and-cancer-from-the-national-inpatient-sample-database
#3
Ayman Elbadawi, Islam Y Elgendy, Le Dung Ha, Basarat Baig, Marwan Saad, Hussain Adly, Gbolahan O Ogunbayo, Odunayo Olorunfemi, Matthew S Mckillop, Scott A Maffett
Limited data are available regarding the impact of cancer on cerebrovascular accidents in patients with atrial fibrillation (AF). We queried the Nationwide Inpatient Survey Database to identify patients who have diagnostic code for AF. We performed a 1:1 propensity matching based on the CHA2DS2VASc score and other risk factors between patients with AF who had lung, breast, colon, and esophageal cancer, and those who did not (control). The final cohort included a total of 31,604 patients. The primary outcome of in-hospital cerebrovascular accidents (CVA) was lower in the cancer group than in the control group (4% vs 7%, p < 0...
December 20, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29352337/impact-of-hepatitis-b-carrier-status-on-the-outcomes-of-surgical-treatment-of-colorectal-liver-metastases
#4
Kin Pan Au, Kenneth Siu Ho Chok, Albert Chi Yan Chan, Wing Chiu Dai, Tan To Cheung, Chung Mau Lo
BACKGROUND: Chronic hepatitis B virus (HBV) infection is associated with a lower incidence of colorectal liver metastases. We explored the impact of HBV carrier status on outcomes of surgical treatment of colorectal liver metastases. METHODS: A retrospective analysis was conducted for consecutive patients undergoing liver resection for colorectal liver metastases from 2000 to 2016. HBV carriers were matched with controls by propensity scoring. RESULTS: 304 patients with known HBV carrier status who underwent resection of colorectal liver metastases were studied...
January 19, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29351596/freedom-solo%C3%A2-versus-trifecta%C3%A2-bioprostheses-clinical-and-haemodynamic-evaluation-after-propensity-score-matching
#5
Rui J Cerqueira, Renata Raimundo, Soraia Moreira, Francisca A Saraiva, Marta Andrade, Elson Salgueiro, Jorge Almeida, Mário Jorge Amorim, Paulo Pinho, André P Lourenço, Adelino Leite-Moreira
OBJECTIVES: The goal of this study was to compare the stentless Freedom Solo® (FS) and the stented Trifecta® (TF) aortic bioprostheses with regard to haemodynamic profile, left ventricular mass regression and early and late postoperative outcomes and survival. METHODS: A longitudinal cohort study of consecutive patients undergoing aortic valve replacement (2009-16) with either the FS or TF at 1 centre was performed. Local databases and national records were queried...
January 16, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29350570/benefits-of-laparoscopic-approach-for-resection-of-liver-tumors-in-cirrhotic-patients
#6
Fabien Le Roux, Lionel Rebibo, Cyril Cosse, Denis Chatelain, Eric Nguyen-Khac, Rachid Badaoui, Jean-Marc Regimbeau
INTRODUCTION: Liver resection in cirrhotic patients is associated with increased morbidity and mortality. The objective of this study was to compare short-term results of laparoscopic resection (LR) and open surgery (OS) for minor liver resection in patients with hepatocellular carcinoma (HCC) hepatocellularcarcinoma on nontumor cirrhotic liver (HCC/F4) and patients with colorectal cancer liver metastases (CRLMs) colorectal liver metastases on healthy liver (CRLM/F0). MATERIALS AND METHODS: Between January 2005 and December 2014, all patients undergoing liver resection (n = 754) were included in this study...
January 19, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29350291/decompressive-surgery-for-lumbar-spinal-stenosis-across-the-atlantic-a-comparison-of-preoperative-mri-between-matched-cohorts-from-the-us-and-norway
#7
Amandeep Bhalla, Thomas D Cha, Clemens Weber, Ulf Nerland, Sasha Gulati, Greger Lønne
BACKGROUND: There are no uniform guidelines regarding when to operate for Lumbar Spinal Stenosis (LSS). As we apply findings from clinical research from one population to the next, elucidating similarities or differences provides important context for the validity of extrapolating clinical outcomes. The aim of this study was to compare the morphological severity of lumbar spinal stenosis on preoperative MRI in patients undergoing decompressive surgery in Boston, USA, and Trondheim, Norway...
January 19, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29349832/effects-of-yoga-interventions-practiced-in-heated-and-thermoneutral-conditions-on-endothelium-dependent-vasodilation-the-bikram-yoga-heart-study
#8
Stacy D Hunter, Jitanan Laosiripisan, Ahmed Elmenshawy, Hirofumi Tanaka
We have previously documented improvements in endothelium-dependent vasodilation with a Bikram (hot) yoga intervention in middle-aged adults. Presently, the effect of environmental temperature in hot yoga on endothelial function is unknown. PURPOSE: The purpose of this investigation was to determine the effects of Bikram yoga interventions performed in the heated and thermoneutral conditions on endothelium-dependent vasodilation. METHODS: Fifty-two sedentary but apparently healthy adults aged 40-60 years were randomly assigned to one of three groups: Bikram yoga practiced at 40...
January 18, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29349709/the-host-response-in-critically-ill-sepsis-patients-on-statin-therapy-a-prospective-observational-study
#9
Maryse A Wiewel, Brendon P Scicluna, Lonneke A van Vught, Arie J Hoogendijk, Aeilko H Zwinderman, René Lutter, Janneke Horn, Olaf L Cremer, Marc J Bonten, Marcus J Schultz, Tom van der Poll
BACKGROUND: Statins can exert pleiotropic anti-inflammatory, vascular protective and anticoagulant effects, which in theory could improve the dysregulated host response during sepsis. We aimed to determine the association between prior statin use and host response characteristics in critically ill patients with sepsis. METHODS: We performed a prospective observational study in 1060 patients admitted with sepsis to the mixed intensive care units (ICUs) of two hospitals in the Netherlands between January 2011 and July 2013...
January 18, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29349644/does-statin-benefits-patients-with-heart-failure-undergoing-percutaneous-coronary-intervention-findings-from-the-melbourne-interventional-group-registry
#10
Ken Lee Chin, Rory Wolfe, Christopher M Reid, Andrew Tonkin, Ingrid Hopper, Angela Brennan, Nick Andrianopoulos, Stephen J Duffy, David Clark, Andrew Ajani, Danny Liew
PURPOSE: The effectiveness of statins in improving clinical outcomes among patients with heart failure (HF) undergoing percutaneous coronary intervention (PCI) is unclear. We examined the association between use of statins and clinical outcomes in patients with HF included in the Melbourne Interventional Group registry. METHODS: Patients were followed from 30 days to 1 year post-PCI for a primary composite outcome of all-cause mortality and hospitalisation for cardiovascular (CV) causes...
January 18, 2018: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29349545/risk-of-discontinuation-of-clopidogrel-after-1-month-following-bare-metal-stents-a-propensity-score-adjusted-comparison-with-continued-administration-of-clopidogrel-after-drug-eluting-stents
#11
Christian M Valina, Sebastian Merz, Nikolaus Löffelhardt, Michael Amann, Miroslaw Ferenc, Christian Stratz, Franz-Josef Neumann, Willibald Hochholzer
In patients at high risk for bleeding undergoing percutaneous coronary intervention (PCI) the use of bare-metal-stent (BMS) is considered an option that allows discontinuation of clopidogrel after 4 weeks. We sought to investigate the risk of early discontinuation of clopidogrel in patients with BMS as compared with a 6-month course of clopidogrel after DES in patients with or without high on-treatment platelet reactivity (HTPR). In 765 consecutive patients undergoing PCI after loading with clopidogrel 600 mg, HTPR was tested by optical aggregometry and defined as residual platelet reactivity > 14%...
January 18, 2018: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29349262/mothers-labor-market-choices-and-child-development-outcomes-in-chile
#12
Sarah A Reynolds, Lia C H Fernald, Jere R Behrman
This paper examines associations between labor market participation of Chilean mothers and the cognitive, language, and socio-economic development of their children. Using a nationally-representative sample of 3-year-old children, we test if mothers' work intensity in the two previous years is associated with child development outcomes; data were collected in 2010 when children were one year old, and again in 2012, when they were three years old. We find that children who were three years old with mothers who worked for higher fractions of their children's lives in the previous two years perform significantly better on all tests (cognitive, language, socio-emotional) than children whose mothers had worked less, while controlling for baseline test performance...
December 2017: SSM—Population Health
https://www.readbyqxmd.com/read/29348868/luminal-like-her2-negative-stage-ia-breast-cancer-a-multicenter-retrospective-study-on-long-term-outcome-with-propensity-score-analysis
#13
Carmine De Angelis, Massimo Di Maio, Anna Crispo, Mario Giuliano, Francesco Schettini, Marta Bonotto, Lorenzo Gerratana, Donatella Iacono, Marika Cinausero, Ferdinando Riccardi, Giuseppe Ciancia, Michelino De Laurentiis, Fabio Puglisi, Sabino De Placido, Grazia Arpino
The benefit of adding chemotherapy (CT) to adjuvant hormone therapy (HT) in stage IA luminal-like HER2-negative breast cancer (BC) is unclear. We retrospectively evaluated predictive factors and clinical outcome of 1,222 patients from 4 oncologic centers. Three hundred and eighty patients received CT and HT (CT-cohort) and 842 received HT alone (HT-cohort). Disease-free survival (DFS) and overall survival (OS) were evaluated with univariate and multivariate analyses. We also applied the propensity score methodology...
December 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29348857/influenza-vaccination-might-reduce-the-risk-of-ischemic-stroke-in-patients-with-atrial-fibrillation-a-population-based-cohort-study
#14
Pai-Feng Kao, Ju-Chi Liu, Yi-Ping Hsu, Li-Chin Sung, Tsung-Yeh Yang, Wen-Rui Hao, Ying-Chin Lin, Szu-Yuan Wu
Purpose: Atrial fibrillation (AF) is associated with the risk of ischemic stroke, regardless of the administration of appropriate antithrombotic prophylaxis. This study investigated whether influenza vaccination is associated with the risk of ischemic stroke, to determine a solution to reduce this risk in patients with AF. Methods: We used data from the Taiwan National Health Insurance Research Database. The study cohort comprised all patients diagnosed as having AF (n = 14 454) before January 1, 2005; these patients were followed until December 31, 2012...
December 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29346828/dynamic-posterior-stabilization-versus-posterior-lumbar-intervertebral-fusion-a-matched-cohort-study-based-on-the-spine-tango-registry
#15
Kathrin S Bieri, Kelly Goodwin, Emin Aghayev, Hans-Joachim Riesner, Ralph Greiner-Perth
PURPOSE:  The primary aim of dynamic stabilization is to stabilize the spine and preserve function without overstressing adjacent segments, which is a potential risk of fusion surgery. However, direct comparative analyses of the two approaches are still limited, and little is known about the association of patient-reported outcomes with these treatment options. OBJECTIVE:  To compare the clinical outcomes of dynamic posterior stabilization using the DSS Stabilization System (Paradigm Spine, LLC, New York, New York, United States) versus posterior lumbar intervertebral fusion (PLIF) based on data from a spine registry...
January 18, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29346798/uric-acid-in-the-follow-up-determines-30-decline-in-estimated-gfr-over-2-years-a-propensity-score-analysis
#16
Wen Xiu Chang, Ning Xu, Takanori Kumagai, Ryutaro Iijima, Kaito Waki, Masaki Yamanaka, Michito Nagura, Shigeyuki Arai, Yoshifuru Tamura, Shigeru Shibata, Yoshihide Fujigaki, Shunya Uchida
BACKGROUND/AIMS: Higher level of serum uric acid (SUA) predicts early entry to dialysis in chronic kidney disease (CKD) patients. However, a short-term effect of SUA remains to be elucidated using a novel surrogate endpoint. METHODS: Japanese CKD stage 3 to 4 patients were retrospectively examined (n= 701). The follow-up level of SUA was estimated as time-averaged uric acid (TA-UA). A propensity score for 6.0, 6.5 or 7.0 mg/dL of TA-UA was respectively calculated using baseline 23 covariates...
December 4, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29346259/do-patients-supported-with-continuous-flow-left-ventricular-assist-device-cf-lvads-have-a-sufficient-risk-of-death-to-justify-a-priority-allocation-a-propensity-score-matched-analysis-of-patients-listed-in-unos-status-2
#17
Stefano Mastrobuoni, Angelo Maria Dell'Aquila, Olivier Van Caenegem, Alain Poncelet, Luc-Marie Jacquet, Josè Garcia
BACKGROUND: Outcomes of Continuous Flow Left Ventricular Assist Devices (CF-LVADs) as bridge to transplant have significantly improved. The question has arisen whether patients on CF-LVADs have an increased risk of death on the waiting list as to justify a priority allocation (status 1). The aim of this study was to compare the survival following implantation of CF-LVADs to the survival on the waiting list for patients initially listed in United Network for Organ Sharing (UNOS) status 2...
January 18, 2018: Transplantation
https://www.readbyqxmd.com/read/29346041/post-treatment-mortality-after-surgery-and-stereotactic-body-radiotherapy-for-early-stage-non-small-cell-lung-cancer
#18
William A Stokes, Michael R Bronsert, Robert A Meguid, Matthew G Blum, Bernard L Jones, Matthew Koshy, David J Sher, Alexander V Louie, David A Palma, Suresh Senan, Laurie E Gaspar, Brian D Kavanagh, Chad G Rusthoven
Purpose In early-stage non-small cell lung cancer (NSCLC), post-treatment mortality may influence the comparative effectiveness of surgery and stereotactic body radiotherapy (SBRT), with implications for shared decision making among high-risk surgical candidates. We analyzed early mortality after these interventions using the National Cancer Database. Patients and Methods We abstracted patients with cT1-T2a, N0, M0 NSCLC diagnosed between 2004 and 2013 undergoing either surgery or SBRT. Thirty-day and 90-day post-treatment mortality rates were calculated and compared using Cox regression and propensity score-matched analyses...
January 18, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29344700/dual-mobility-hip-arthroplasty-provides-better-outcomes-compared-to-hemiarthroplasty-for-displaced-femoral-neck-fractures-a-retrospective-comparative-clinical-study
#19
Yong Tae Kim, Je-Hyun Yoo, Min Ki Kim, Sanghyun Kim, Jihyo Hwang
PURPOSE: Total hip arthroplasty with a dual mobility cup (DMC) is a proposed alternative to the widely performed bipolar hemiarthroplasty (BHA) for treating displaced intracapsular femoral neck fractures (DFNF) in the elderly. However, the comparison between the two modalities has not been extensively conducted thus far. METHODS: A retrospective cohort study was conducted with DFNF patients aged over 65 years who were treated either by BHA or DMC. After propensity matching each group comprised 84 patients (168 patients in total) and was analyzed using peri-operative and post-operative parameters...
January 17, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29344689/early-versus-late-tracheostomy-in-trauma-patients-a-propensity-matched-cohort-study-of-5-years-data-at-a-single-institution-in-korea
#20
Byung Hee Kang, Jayun Cho, John Cook-Jong Lee, Kyoungwon Jung
BACKGROUND: Although there have been many studies dealing with tracheostomy timing in trauma patients, the optimal timing is still being debated. This study aimed to compare outcomes between early tracheostomy (ET) and late tracheostomy (LT) in trauma populations to estimate the optimal timing of tracheostomy after intubation. METHODS: We retrospectively reviewed the 5 years' data of trauma patients who underwent tracheostomy during their acute intensive care unit (ICU) stay...
January 17, 2018: World Journal of Surgery
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