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https://www.readbyqxmd.com/read/28813574/dynamic-imaging-of-the-eye-optic-nerve-and-extraocular-muscles-with-golden-angle-radial-mri
#1
Saikat Sengupta, David S Smith, Alex K Smith, E Brian Welch, Seth A Smith
Purpose: The eye and its accessory structures, the optic nerve and the extraocular muscles, form a complex dynamic system. In vivo magnetic resonance imaging (MRI) of this system in motion can have substantial benefits in understanding oculomotor functioning in health and disease, but has been restricted to date to imaging of static gazes only. The purpose of this work was to develop a technique to image the eye and its accessory visual structures in motion. Methods: Dynamic imaging of the eye was developed on a 3-Tesla MRI scanner, based on a golden angle radial sequence that allows freely selectable frame-rate and temporal-span image reconstructions from the same acquired data set...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28802419/recalcitrant-aseptic-atrophic-non-union-of-the-shaft-of-the-humerus-after-failure-of-surgical-treatment-management-by-excision-of-non-union-bone-grafting-and-stabilization-by-lcp-in-different-modes
#2
Sudhir Babhulkar, Sushrut Babhulkar, Aditya Vasudev
Non-union of the humeral shaft is infrequently noticed after surgical fixation. Sixty eight patients whose osteosynthesis of humeral shaft had failed leading to non-union were identified over a duration of 10 years from (January 2006 to December 2015). Clinical and radiographical follow-up was available for 64 patients (4 patients were lost for follow-up), with a mean age of 58 years (range 25-78 years). All patients had aseptic atrophic non-union of either: proximal shaft (n=12), mid shaft (n=38), and lower shaft (n=14)...
August 2017: Injury
https://www.readbyqxmd.com/read/28799442/the-use-of-innervated-radial-artery-superficial-palmar-branch-perforator-free-flap-for-complex-digital-injuries-reconstruction
#3
Zhenglin Chi, Georgios Pafitanis, Luis Eduardo Parra Pont, Roshan Vijayan, Stefano Marcelli, Weiyang Gao, Zan Li, Xiao Zhou, Dajiang Song, Peng Yang
Loco-regional flaps have been widely used for the reconstruction of digital injuries without requiring microvascular anastomosis, however, they result in scarring and compromised functional outcomes. This study demonstrates our experience utilizing the innervated radial artery superficial palmar branch (RASPB) perforator free flap for complex digital injury reconstruction. From May 2007 to March 2014, the innervated RASPB perforator free flap was used to reconstruct 79 distal complex hand and digital soft tissue defects of which 14 were used to re-vascularise the distal digit in a flow-through fashion...
August 11, 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28797603/chronic-traumatic-stress-impairs-memory-in-mice-potential-roles-of-acetylcholine-neuroinflammation-and-corticotropin-releasing-factor-expression-in-the-hippocampus
#4
Ami Bhakta, Kartheek Gavini, Euitaek Yang, Lani Lyman-Henley, Kodeeswaran Parameshwaran
Chronic stress in humans can result in multiple adverse psychiatric and neurobiological outcomes, including memory deficits. These adverse outcomes can be more severe if each episode of stress is very traumatic. When compared to acute or short term stress relatively little is known about the effects of chronic traumatic stress on memory and molecular changes in hippocampus, a brain area involved in memory processing. Here we studied the effects of chronic traumatic stress in mice by exposing them to adult Long Evan rats for 28 consecutive days and subsequently analyzing behavioral outcomes and the changes in the hippocampus...
August 8, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28795436/anatomic-characterization-of-the-humeral-nutrient-artery-application-to-fracture-and-surgery-of-the-humerus
#5
Koichiro Ichimura, Shota Kinose, Yuto Kawasaki, Taro Okamura, Kota Kato, Tatsuo Sakai
Anatomic characterization of the humeral nutrient artery varies among the several textbooks on human anatomy. To clarify the anatomic characteristics of the humeral nutrient artery, we reexamined its origin and course by cadaveric dissection. In typical cases, one prominent nutrient foramen was situated on the anteromedial surface of the humeral shaft, and the nutrient canal distally penetrated the cortical bone layer. The humeral nutrient artery originated from the brachial artery below the level of the nutrient foramen as a short ascending branch...
August 10, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28780727/interventions-for-humeral-shaft-fractures-mixed-treatment-comparisons-of-clinical-trials
#6
Y Zhao, J Wang, W Yao, Q Cai, Y Wang, W Yuan, S Gao
We designed a study to compare the efficacy of five main therapeutic options, including external fixation, open reduction and plate osteosynthesis (ORPO), minimally invasive plate osteosynthesis (MIPO), dynamic compression plate (DCP), and intramedullary nail (IMN) in treating humeral shaft fractures. Our results indicated that MIPO and IMN were recommended as the optimal treatments for clinical use. PURPOSE: Nowadays, five main therapeutic options are used in treating humeral shaft fractures: external fixation, open reduction and plate osteosynthesis (ORPO), minimally invasive plate osteosynthesis (MIPO), dynamic compression plate (DCP), and intramedullary nail (IMN)...
August 5, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28777535/electrospun-nanofibers-new-concepts-materials-and-applications
#7
Jiajia Xue, Jingwei Xie, Wenying Liu, Younan Xia
Electrospinning is a simple and versatile technique that relies on the electrostatic repulsion between surface charges to continuously draw nanofibers from a viscoelastic fluid. It has been applied to successfully produce nanofibers, with diameters down to tens of nanometers, from a rich variety of materials, including polymers, ceramics, small molecules, and their combinations. In addition to solid nanofibers with a smooth surface, electrospinning has also been adapted to generate nanofibers with a number of secondary structures, including those characterized by a porous, hollow, or core-sheath structure...
August 4, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28777281/recovery-of-motor-nerve-injuries-associated-with-displaced-extension-type-pediatric-supracondylar-humerus-fractures
#8
Benjamin J Shore, Bryce T Gillespie, Patricia E Miller, Donald S Bae, Peter M Waters
BACKGROUND: Nerve injuries occur in approximately 11% of pediatric extension supracondylar humerus fractures (SCHF), yet there is scarce literature to guide clinicians on management. The primary goal of this study was to report the presentation, treatment, and outcome of motor nerve injuries associated with extension SCHF. Our secondary goal was to determine which injury and treatment factors were associated with prolonged motor nerve recovery. METHODS: Two hundred forty-four traumatic nerve injuries associated with extension SCHF treated at a single institution between 1996 and 2012 were reviewed...
August 2, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28774935/comparing-optical-coherence-tomography-radial-and-cube-scan-patterns-for-measuring-bruch-s-membrane-opening-minimum-rim-width-bmo-mrw-in-glaucoma-and-healthy-eyes-cross-sectional-and-longitudinal-analysis
#9
Sami W Kabbara, Linda M Zangwill, Rusdeep Mundae, Naama Hammel, Christopher Bowd, Felipe A Medeiros, Robert N Weinreb, Akram Belghith
AIM: To compare the cube and radial scan patterns of the spectral domain optical coherence tomography (SD-OCT) for quantifying the Bruch's membrane opening minimum rim width (BMO-MRW). METHODS: Sixty healthy eyes and 189 glaucomatous eyes were included. The optic nerve head cube and radial pattern scans were acquired using Spectralis SD-OCT. BMO-MRWs were automatically delineated using the San Diego Automated Layer Segmentation Algorithm. The BMO-MRW diagnostic accuracy for glaucoma detection and rates of change derived from the two scan patterns were compared...
August 3, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28768847/cross-sectional-analysis-of-a-large-cohort-with-x-linked-charcot-marie-tooth-disease-cmtx1
#10
Francis B Panosyan, Matilde Laura, Alexander M Rossor, Chiara Pisciotta, Giuseppe Piscosquito, Joshua Burns, Jun Li, Sabrina W Yum, Richard A Lewis, John Day, Rita Horvath, David N Herrmann, Michael E Shy, Davide Pareyson, Mary M Reilly, Steven S Scherer
OBJECTIVE: To extend the phenotypic description of Charcot-Marie-Tooth disease (CMTX1) and to draw new genotype-phenotype relationships. METHODS: Mutations in GJB1 cause the main X-linked form of CMTX (CMTX1). We report cross-sectional data from 160 patients (from 120 different families, with 89 different mutations) seen at the Inherited Neuropathies Consortium centers. RESULTS: We evaluated 87 males who had a mean age of 41 years (range 10-78 years) and 73 females who had a mean age of 46 years (range 15-84 years)...
August 2, 2017: Neurology
https://www.readbyqxmd.com/read/28760135/the-first-data-on-the-innervation-of-the-lophophore-in-the-rhynchonelliform-brachiopod-hemithiris-psittacea-what-is-the-ground-pattern-of-the-lophophore-in-lophophorates
#11
Elena N Temereva, Tatyana V Kuzmina
BACKGROUND: The nervous system in brachiopods has seldom been studied with modern methods. An understanding of lophophore innervation in adult brachiopods is useful for comparing the innervation of the same lophophore type among different brachiopods and can also help answer questions about the monophyly of the lophophorates. Although some brachiopods are studied with modern methods, rhynchonelliform brachiopods still require investigation. The current study used transmission electron microscopy, immunocytochemistry, and confocal laser scanning microscopy to investigate the nerve system of the lophophore and tentacles in the rhynchonelliform Hemithiris psittacea...
July 31, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28760131/atypical-injury-of-radial-nerve-after-humeral-shaft-fracture
#12
Murat Yeşil, Özal Özcan, Ömer Ali Kaya, Sadık Emre Erginoğlu
As general opinion, conservative treatment is usually suggested for closed humeral shaft fractures with radial nerve palsy; however, some authors advocate early surgical exploration, particularly for spiral fractures of the humerus accompanied with radial nerve palsy. In this article, we present a case of radial nerve palsy after fracture of the proximal-middle third of humeral shaft. A surgical exploration of the nerve revealed that the sharp tip of the bony fragment at fracture site was penetrated into the nerve and separated the nerve as two bands, almost like a ″buttonhole″ injury...
August 2017: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/28760123/is-locked-compressive-intramedullary-nailing-for-adult-humerus-shaft-fractures-advantageous
#13
Fatih Duygun, Cengiz Aldemir
OBJECTIVES: This study aims to evaluate the radiological and functional outcomes of locked compressive intramedullary nailing (IMN) cases in adult humerus shaft fractures. PATIENTS AND METHODS: A total of 24 patients (12 males, 12 females; mean age 42 years; range 23 to 55 years) with humerus fractures were treated with locked compressive IMN at the Orthopedics and Traumatology Clinic, Antalya Training and Research Hospital between December 2009 and March 2015. Fluoroscopy was used only to check fracture reduction before the reaming procedure...
August 2017: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/28744730/relationships-between-the-integrity-and-function-of-lumbar-nerve-roots-as-assessed-by-diffusion-tensor-imaging-and-neurophysiology
#14
S Y Chiou, P J Hellyer, D J Sharp, R D Newbould, M C Patel, P H Strutton
PURPOSE: Diffusion tensor imaging (DTI) has shown promise in the measurement of peripheral nerve integrity, although the optimal way to apply the technique for the study of lumbar spinal nerves is unclear. The aims of this study are to use an improved DTI acquisition to investigate lumbar nerve root integrity and correlate this with functional measures using neurophysiology. METHODS: Twenty healthy volunteers underwent 3 T DTI of the L5/S1 area. Regions of interest were applied to L5 and S1 nerve roots, and DTI metrics (fractional anisotropy, mean, axial and radial diffusivity) were derived...
July 25, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28740768/fmri-after-phalloplasty-with-nerve-anastomosis-in-a-trans-man-patient
#15
Roberto Doria-Medina, Åsa Carlsson, Emma H Jönsson, Lars Jönsson, Andri Thorarinsson, Mattias Lidén, Gennaro Selvaggi
We report on a case of a trans-man patient, who underwent penile reconstruction with the use of a radial forearm flap, urethroplasty, vaginectomy and scrotoplasty, insertion of testicle implants, and penile erection implants, similar to previously described methods. One of the requirements for an ideal phalloplasty is the preservation of erogenous sensitivity, which is often demanded by the patients for fulfilling their sexual well-being. For the first time known to us, we use a functional magnetic resonance imaging following radial forearm flap phalloplasty with nerve anastomosis to assess the cortical activation after clitoral stimulation...
June 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28734534/elbow-vascularized-composite-allotransplantation-surgical-anatomy-and-technique
#16
Zvi Steinberger, Heng Xu, Nikolas H Kazmers, Stephanie Thibaudeau, Russel G Huffman, L Scott Levin
BACKGROUND: Elbow reconstruction with vascularized composite allotransplantation (VCA) may hold promise in treating end-stage arthritis as no current treatment is both functional and durable. We describe the vascular and gross anatomy of the elbow in the context of VCA procurement and propose a step-by-step surgical technique for human elbow VCA. METHODS: We injected latex in the arterial tree of 16 fresh adult cadaveric upper extremities. We identified and measured arteries and nerves and their branch points relative to the medial epicondyle...
August 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28725918/a-comprehensive-review-of-motor-innervation-of-the-hand-variations-and-clinical-significance
#17
REVIEW
Sacha Wynter, Lakal Dissabandara
PURPOSE: The objective of the present review is to assemble the recognized anatomical variations, classifications, and clinical evidence with regard to innervation of the hand and discuss the clinical significance of these variations. METHODS: The material for this review was obtained by exploring PubMed and Google Scholar (search terms: hand innervation, variations of ulnar nerve, variations of median nerve, variations of radial nerve) as well as from standard anatomy texts...
July 19, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28720008/a-cadaveric-study-of-the-thread-trigger-finger-release-the-first-annular-pulley-transection-through-thread-transecting-technique
#18
Danqing Guo, Danzhu Guo, Joseph Guo, Logan C McCool, Brionn Tonkin
BACKGROUND: After the thread transecting technique was successfully applied for the thread carpal tunnel release, we researched using the same technique in the thread trigger finger release (TTFR). This study was designed to test the operational feasibility of the TTFR on cadavers and verify the limits of division on the first annular (A1) pulley to ensure a complete trigger finger release with minimal iatrogenic injuries. METHODS: The procedure of TTFR was performed on 14 fingers and 4 thumbs of 4 unembalmed cadaveric hands...
March 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28718333/anomalous-radial-artery-as-an-incidental-finding-during-a-routine-carpal-tunnel-release
#19
Charles A Gober, Tarik Mujadzic, John E Hershman, Mirsad M Mujadzic
BACKGROUND: Compression of the median nerve at the wrist, or carpal tunnel syndrome, is the most commonly recognized nerve entrapment syndrome. Carpal tunnel syndrome is usually caused by compression of the median nerve due to synovial swelling, tumor, or anomalous anatomical structure within the carpal tunnel. METHODS: During a routine carpal tunnel decompression, a large vessel was identified within the carpal tunnel. RESULTS: The large vessel was the radial artery...
February 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28718309/intra-articular-fracture-of-the-base-of-the-first-metacarpal-bone-treatment-through-a-volar-approach
#20
Violeta Levy, Marcelo Mazzola, Martín Gonzalez
BACKGROUND: Management of Bennett fractures has been controversial. Early reports supported closed reduction and casting with or without percutaneous pinning. Later, open reduction and internal fixation was advocated. The purpose of this article is to assess the surgical treatment using a direct volar approach. METHODS: Between March 2008 and December 2014, 21 patients with intra-articular first metacarpal fractures displaced more than 1 mm were operated on using a direct volar approach...
January 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
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