keyword
MENU ▼
Read by QxMD icon Read
search

prognostic index

keyword
https://www.readbyqxmd.com/read/27932136/prognostic-value-of-high-sensitivity-troponin-t-to-identify-patients-at-risk-of-left-ventricular-graft-dysfunction-after-heart-transplantation
#1
A B Méndez, J Ordonez-Llanos, S Mirabet, J Galan, M L Maestre, V Brossa, M T Rivilla, L López, T Koller, A Sionis, E Roig
Primary graft dysfunction after heart transplantation (HTx) has a very high mortality rate, especially if the left ventricle (PGD-LV) is involved. Early diagnosis is important to select the appropriate therapy to improve prognosis. The value of high-sensitivity troponin T (HS-TNT) measurement obtained at patient arrival at the intensive care unit was analyzed in 71 HTx patients. Mild or moderate PGD-LV was defined by hemodynamic compromise with one of the following criteria: left ventricular ejection fraction <40%, hemodynamic compromise with right atrial pressure >15 mm Hg, pulmonary capillary wedge pressure >20 mm Hg, cardiac index <2...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27932030/a-clinically-applicable-muscular-index-predicts-long-term-survival-in-resectable-pancreatic-cancer
#2
Daniel Delitto, Sarah M Judge, Thomas J George, George A Sarosi, Ryan M Thomas, Kevin E Behrns, Steven J Hughes, Andrew R Judge, Jose G Trevino
BACKGROUND: The relationship between myopenia, nutritional status, and long-term oncologic outcomes remains poorly characterized in patients with clinically resectable pancreatic cancer. We sought to reliably quantify prognostic indicators of preoperative cachexia in a manner applicable to any clinical setting. METHODS: Preoperative computed tomographies were available electronically and suitable for analysis in 73 of 82 consecutive patients with pancreatic cancer undergoing pancreatoduodenectomy between November 2010 and February 2014...
December 5, 2016: Surgery
https://www.readbyqxmd.com/read/27931133/outcomes-for-transformed-follicular-lymphoma-in-the-rituximab-era-the-royal-marsden-experience-2003-2013
#3
Mary Gleeson, Eliza A Hawkes, Clare Peckitt, Andrew Wotherspoon, Ayoma Attygalle, Bhupinder Sharma, Yong Du, Mark Ethell, Mike Potter, Claire Dearden, Alan Horwich, Ian Chau, David Cunningham
Survival for transformed follicular lymphoma (tFL) has improved in the rituximab era and the need for upfront stem cell transplantation (SCT) is unclear. We evaluated the outcomes for all patients treated with first-line chemotherapy for histologically-proven tFL at our institution from 2003-2013 (n = 87). The majority of patients (89.7%) did not receive a SCT as part of first-line management. With a median follow-up of 7.8 years the 5-year overall survival (OS) for all patients was 61.7%. Patients treated with R-CHOP without upfront SCT (n = 55/87) had a 5-year OS of 64...
December 8, 2016: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/27931104/malnutrition-risk-questionnaire-combined-with-body-composition-measurement-in-malnutrition-screening-in-inflammatory-bowel-disease
#4
Ágnes Anna Csontos, Andrea Molnár, Zsolt Piri, Erzsébet Pálfi, Pál Miheller
The purpose of malnutrition screening is to predict the probability of a worse outcome due to nutritional factors. The Malnutrition Universal Screening Tool (MUST) can be used for screening in inflammatory bowel disease (IBD); however, it does not provide details about body composition. Our aim was to assess the body composition and combine this with the MUST method to screen risk of malnutrition and sarcopenia. A total of 173 IBD outpatients were enrolled in this cross-sectional study. The MUST scale indicated 21...
December 9, 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27931089/prognostic-implications-of-epicardial-fat-volume-quantification-in-acute-pericarditis
#5
George Lazaros, Alexios S Antonopoulos, Evangelos K Oikonomou, Panagiotis Vasileiou, Evangelos Oikonomou, Evangelia Stroumpouli, Apostolos Karavidas, Charalambos Antoniades, Dimitris Tousoulis
BACKGROUND: The pathophysiology of acute pericarditis remains largely unknown and biomarkers are needed to identify patients susceptible to complications. Since adipose tissue has a pivotal role in cardiovascular disease pathogenesis, we hypothesized that quantification of epicardial fat volume (EFV) provides prognostic information in patients with acute pericarditis. MATERIALS AND METHODS: Fifty (n=50) patients with first diagnosis of acute pericarditis were enrolled in this study...
December 8, 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27930440/association-of-night-time-home-blood-pressure-with-night-time-ambulatory-blood-pressure-and-target-organ-damage-a-systematic-review-and-meta-analysis
#6
Anastasios Kollias, Angeliki Ntineri, George S Stergiou
OBJECTIVE: Night-time ambulatory blood pressure (nABP) is the most important aspect of the blood pressure profile in terms of prognosis. Novel low-cost home monitors allow automated night-time blood pressure monitoring (nHBP). This study reviewed the evidence on the association of nHBP with nABP and preclinical organ damage. METHODS: Systematic review and meta-analysis. RESULTS: Analysis of six studies (n = 1404) showed pooled difference between nHBP and nABP (SBP/DBP) at 1...
December 7, 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27928807/prognostic-value-of-circulating-tumor-cells-in-castration-resistant-prostate-cancer-a-meta-analysis
#7
Yuxiao Zheng, Cheng Zhang, Jie Wu, Gong Cheng, Haiwei Yang, Lixin Hua, Zengjun Wang
PURPOSE: The prognostic value of circulating tumor cells (CTC) detected in castration-resistant prostate cancer(CRPC) is currently under debate. The aim of our meta-analysis was to evaluate the prognostic effect of CTC andto elucidate whether the detection of CTC in the peripheral blood (PB) of patients diagnosed with CRPC can beused as an independent prognostic factor for survival. MATERIALS AND METHODS: The Pubmed, Science Citation Index, Cochrane Database, Embase Cell Research databaseand the references in relevant studies were systematically searched...
December 8, 2016: Urology Journal
https://www.readbyqxmd.com/read/27927666/epigenetic-biomarkers-in-progression-from-non-dysplastic-barrett-s-oesophagus-to-oesophageal-adenocarcinoma-a-systematic-review-protocol
#8
T Nieto, C L Tomlinson, J Dretzke, S Bayliss, M Dilworth, A D Beggs, O Tucker
INTRODUCTION: Barrett's oesophagus (BO), a metaplastic condition affecting the lower oesophagus due to long-standing gastro-oesophageal reflux and chronic inflammation, is a precursor lesion for oesophageal adenocarcinoma (OADC). There is no clinical test to predict which patients with BO will progress to OADC. The British Society of Gastroenterology recommends endoscopic surveillance of patients with BO. Epigenetic changes have been well characterised in the neoplastic progression of ulcerative colitis to colonic carcinoma, another gastrointestinal cancer associated with chronic inflammation...
December 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27927629/central-haemodynamics-and-prediction-of-cardiovascular-events-in-patients-with-erectile-dysfunction
#9
Charalambos Vlachopoulos, Nikolaos Ioakeimidis, Konstantinos Rokkas, Athanassios Angelis, Dimitrios Terentes-Printzios, Zisis Kratiras, Christos Georgakopoulos, Dimitrios Tousoulis
BACKGROUND: We investigated whether central hemodynamics predict major adverse cardiovascular events (MACEs) in erectile dysfunction (ED) patients beyond traditional risk factors. METHODS: MACEs in relation to aortic pressures and augmentation index (AIx) were analyzed in 398 patients (mean age, 56 years) with ED but without established cardiovascular (CV) disease. RESULTS: During the mean follow-up period of 6.5 years, a total of 29 (6.5%) MACEs occurred...
December 7, 2016: American Journal of Hypertension
https://www.readbyqxmd.com/read/27926777/a-prospective-multicenter-cohort-study-to-validate-a-simple-performance-status-based-survival-prediction-system-for-oncologists
#10
Takeshi Yamada, Tatsuya Morita, Isseki Maeda, Satoshi Inoue, Masayuki Ikenaga, Yoshihisa Matsumoto, Mika Baba, Ryuichi Sekine, Takashi Yamaguchi, Takeshi Hirohashi, Tsukasa Tajima, Ryohei Tatara, Hiroaki Watanabe, Hiroyuki Otani, Chizuko Takigawa, Yoshinobu Matsuda, Shigeki Ono, Taketoshi Ozawa, Ryo Yamamoto, Hideki Shishido, Naoki Yamamoto
BACKGROUND: Survival prediction systems such as the Palliative Prognostic Index (PPI), which includes the Palliative Performance Scale (PPS), are used to estimate survival for terminally ill patients. Oncologists are, however, less familiar with the PPS in comparison with the Eastern Cooperative Oncology Group (ECOG) performance status (PS). This study was designed to validate a simple survival prediction system for oncologists, the Performance Status-Based Palliative Prognostic Index (PS-PPI), which is a modified form of the PPI based on the ECOG PS...
December 7, 2016: Cancer
https://www.readbyqxmd.com/read/27926682/clinical-outcomes-of-nonunions-of-hindfoot-and-ankle-fusions
#11
Fabian Krause, Alastair S E Younger, Judith F Baumhauer, Timothy R Daniels, Mark Glazebrook, Peter T Evangelista, Michael S Pinzur, Gowreeson Thevendran, Rafe M J Donahue, Christopher W DiGiovanni
BACKGROUND: While nonunion after foot and ankle fusion surgery has been associated with poor outcomes, we are not aware of any longitudinal study on this subject. Thus, we prospectively evaluated the impact of nonunion on clinical outcomes of foot and ankle fusions and identified potential risk factors for nonunion after these procedures. METHODS: Using data from a randomized clinical trial on recombinant human platelet-derived growth factor-BB (rhPDGF-BB; Augment Bone Graft, BioMimetic Therapeutics), union was defined either by assessment of computed tomography (CT) scans at 24 weeks by a reviewer blinded to the type of treatment or by the surgeon's composite assessment of clinical and radiographic findings at 52 weeks and CT findings at 24 or 36 weeks...
December 7, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27925837/a-comprehensive-multimorbidity-index-for-predicting-mortality-in-intensive-care-unit-patients
#12
Hua Min, Sanja Avramovic, Janusz Wojtusiak, Rahul Khosla, Ross D Fletcher, Farrokh Alemi, Raya Elfadel Kheirbek
BACKGROUND: Accurate prediction of mortality for patients admitted to the intensive care units (ICUs) is an important component of medical care. However, little is known about the role of multimorbidity in predicting end of life for high-risk and vulnerable patients. OBJECTIVE: The aim of the study was to derive and validate a multimorbidity risk model in an attempt to predict all-cause mortality at 6 and 12 months posthospital discharge. METHODS: This is a retrospective, observational, clinical cohort study...
December 7, 2016: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/27925180/a-16-yin-yang-gene-expression-ratio-signature-for-er-node-breast-cancer
#13
Wayne Xu, Gaofeng Jia, Nianguang Cai, Shujun Huang, James R Davie, Marshall Pitz, Shantanu Banerji, Leigh Murphy
Breast cancer is one of the leading causes of cancer death in women. It is a complex and heterogeneous disease with different clinical outcomes. Stratifying patients into subgroups with different outcomes could help guide clinical decision making. In this study, we used two opposing groups of genes, Yin and Yang, to develop a prognostic expression ratio signature. Using the METABRIC cohort we identified a16-gene signature capable of stratifying breast cancer patients into four risk levels with intention that low-risk patients would not undergo adjuvant systemic therapy, intermediate-low-risk patients will be treated with hormonal therapy only, and intermediate-high- and high-risk groups will be treated by chemotherapy in addition to the hormonal therapy...
December 7, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27925136/multidimensional-evaluation-of-endogenous-and-health-factors-affecting-food-preferences-taste-and-smell-perception
#14
D Guido, S Perna, M Carrai, R Barale, M Grassi, M Rondanelli
OBJECTIVE: This study, by taking a holistic approach, investigates the relationships between taste, smell sensitivity and food preference with prognostic (endogenous and health) factors including age, gender, genetic taste markers, body mass, cigarette smoking, and number of drugs used. DESIGN: Cross sectional study. SETTING: Northern Italy. PARTICIPANTS: 203 healthy subjects (160 women/43 men; mean age: 58.2±19.8 years) were examined...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27923462/prognostic-implications-of-newly-developed-t-wave-inversion-after-primary-percutaneous-coronary-intervention-in-patients-with-st-segment-elevation-myocardial%C3%A2-infarction
#15
Man-Jong Lee, Ji-Hoon Jang, Myung-Dong Lee, Sung Woo Kwon, Sung-Hee Shin, Sang-Don Park, Seong-Ill Woo, Dae-Hyeok Kim, Jun Kwan, Keum-Soo Park
We investigated the prognostic value of newly developed T-wave inversion after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction. New T-wave inversion was defined as new onset of T-wave inversion after the primary PCI, without negative T waves on the presenting electrocardiogram. The primary end point was the occurrence of major adverse cardiac events (MACE), which consisted of cardiovascular mortality, nonfatal myocardial infarction, and rehospitalization for heart failure...
November 16, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27922975/influence-of-body-mass-index-on-tumor-pathology-and-survival-in-uterine-cancer-a-danish-register-study
#16
Anne Bjerrum Kristensen, Helle Hare-Bruun, Claus Kim Høgdall, Martin Rudnicki
OBJECTIVE: To evaluate the influence of body mass index (BMI) on endometrial tumor pathology, stage and complication rate and to identify individual prognostic factors, such as BMI, in types I and II endometrial cancer. DESIGN: Register study included all Danish women who underwent surgery for uterine cancer or atypical endometrial hyperplasia (International Classification of Diseases-10 codes D070, DC549) 2005 to 2012 (n = 6003). MAIN OUTCOME MEASURES: Impact of BMI on type I and II endometrial cancer survival...
December 3, 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27920368/use-of-the-concordance-index-for-predictors-of-censored-survival-data
#17
Adam R Brentnall, Jack Cuzick
The concordance index is often used to measure how well a biomarker predicts the time to an event. Estimators of the concordance index for predictors of right-censored data are reviewed, including those based on censored pairs, inverse probability weighting and a proportional-hazards model. Predictive and prognostic biomarkers often lose strength with time, and in this case the aforementioned statistics depend on the length of follow up. A semi-parametric estimator of the concordance index is developed that accommodates converging hazards through a single parameter in a Pareto model...
December 5, 2016: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/27919983/prognostic-significance-of-inflammatory-and-nutritional-parameters-in-patients-with-esophageal-cancer
#18
Tatsuya Miyazaki, Makoto Sakai, Makoto Sohda, Naritaka Tanaka, Takehiko Yokobori, Yoko Motegi, Masanobu Nakajima, Minoru Fukuchi, Hiroyuki Kato, Hiroyuki Kuwano
BACKGROUND: We evaluated the following preoperative prognostic factors in patients who underwent esophagectomy for esophageal cancer: C-Reactive protein (CRP), neutrophil-to-lymphocyte ratio (NLR), serum albumin, prognostic nutritional index (PNI), and body mass index (BMI). PATIENTS AND METHODS: This retrospective study included 173 men and 19 women with a mean age of 65.8 years (range=42-86 years) who were scheduled to undergo esophagectomy for esophageal cancer...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27919886/cardiopulmonary-exercise-testing-in-children-with-cystic-fibrosis-one-centre-s-experience
#19
Elise Weir, Paul D Burns, Anne Devenny, David Young, James Y Paton
BACKGROUND: While exercise testing is increasingly used as a prognostic indicator in cystic fibrosis (CF), it is reported to be underused in UK CF centres, particularly in children. Here, we evaluated the cardiopulmonary exercise testing (CPET) results in children and young people with CF at CF annual review and its possible clinical value. METHOD: An observational study comparing CPET results using a cycle ergometer ramp test (peak oxygen uptake (Vo2peak)) and pulmonary function (forced expiratory volume in 1 s (FEV1)) was performed with body mass index (BMI) used as a disease severity marker...
December 5, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27919582/external-validation-of-a-prognostic-model-for-predicting-nonresponse-following-knee-arthroplasty
#20
Daniel L Riddle, Gregory J Golladay, William A Jiranek, Robert A Perera
BACKGROUND: Instruments designed to predict the extent of pain and function following knee arthroplasty (KA) recovery has strong potential to guide patients and clinicians in shared decision making. Our purpose was to test the external validity of a recently developed prognostic instrument designed to estimate the probability of nonresponse following KA. METHODS: We used data from the Osteoarthritis Initiative (OAI), a 9-year multisite National Institutes of Health study designed to examine the natural history of knee osteoarthritis in 4796 subjects...
November 15, 2016: Journal of Arthroplasty
keyword
keyword
35250
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"