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Forensic Pathology

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https://www.readbyqxmd.com/read/27933413/investigation-on-genetic-thrombophilic-factors-in-ffpe-autopsy-tissue-from-subjects-who-died-from-pulmonary-embolism
#1
Francesco Brandimarti, Federica Alessandrini, Mauro Pesaresi, Chiara Catalani, Letizia De Angelis, Roberta Galeazzi, Simona Giovagnetti, Rosaria Gesuita, Elisa Righi, Raffaele Giorgetti, Adriano Tagliabracci
Venous thromboembolism (VTE) is a multifactorial disease determined by a combination of inherited and acquired factors. Inherited factors include mutations in the genes coding for coagulation factors, some of which seem to exert a differential influence on the risk of developing deep vein thrombosis (DVT) and pulmonary embolism (PE). In post-mortem studies of subjects who have died from pulmonary embolism (PE), the analysis of the factors that may have augmented the VTE risk is often limited to acquired factors...
December 9, 2016: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/27930816/trichobezoar-in-vagina-assessment-for-child-sexual-abuse-and-diagnostic-result-of-forensic-science
#2
Özlem Bağ, Buğra Han Acar, Şenol Öztürk, Sevay Alşen, Çiğdem Ecevit
Vaginal discharge and bleeding in children require a through and thoughtful evaluation to diagnose the underlying problem including infections, sexual abuse, and vaginal foreign bodies. We report a 6-year-old girl presenting with bloody vaginal discharge, carefully evaluated for sexual abuse, and finally diagnosed as a vaginal foreign body after vaginoscopy. A rolling hair ball was extracted from the vagina and was diagnosed as trichobezoar pathologically without any endo-ecto-mesodermal residual tissue. The hair ball was genetically detected and diagnosed to belong herself by containing no foreign structure...
December 8, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27927141/a-cautionary-tale-in-forensic-pathology
#3
Michael Burke
No abstract text is available yet for this article.
December 12, 2016: Medical Journal of Australia
https://www.readbyqxmd.com/read/27913880/forensic-3d-documentation-of-skin-injuries
#4
Chiara Villa
An accurate and precise documentation of injuries is fundamental in a forensic pathological context. Photographs and manual measurements are taken of all injuries during autopsies, but ordinary photography projects a 3D wound on a 2D space. Using technologies such as photogrammetry, it is possible to create 3D detailed, to-scale, true-color documentation of skin injuries from 2D pictures. A comparison between the measurements of 165 lesions taken during autopsies and on photogrammetrically processed pictures was performed...
December 2, 2016: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/27896540/variations-in-the-anatomy-of-the-vertebral-artery-cervical-loop-segment-a-potential-predisposing-factor-for-traumatic-basal-subarachnoid-hemorrhage
#5
Jonathan E Medcalf, C Paul Johnson, Azzam Taktak, Silke Grabherr
Fatal traumatic basal subarachnoid hemorrhage (TBSAH) is a characteristic forensic pathological entity, the investigation of which requires special techniques. In Liverpool, post-mortem room angiography is undertaken, followed by complete removal of the vertebral arteries and histological examination. It has been observed that the arterial anatomy can be highly variable, particularly the length and course of the loop segments located between the C2 vertebra and the dura. In a number of cases of TBSAH the loop segments of torn vessels have appeared relatively short...
November 29, 2016: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/27890307/-french-society-of-pediatrics-forensic-pathology-speciality-s-union-to-protect-minors
#6
M Balençon, C Garnier-Jardin, M Lemesle, A P Michard Lenoir, F Paysant, C Rambaud, C Rey-Salmon, V Scolan, B Tisseron, N Vabres
No abstract text is available yet for this article.
December 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27864951/evaluation-of-the-role-of-toxicological-data-in-discriminating-between-h2-s-femoral-blood-concentration-secondary-to-lethal-poisoning-and-endogenous-h2-s-putrefactive-production
#7
Nunziata Barbera, Angelo Montana, Francesca Indorato, Nadia Arbouche, Guido Romano
Hydrogen sulfide is a colorless gas and has a strong odor of rotten eggs. It is absorbed by the upper respiratory tract mucosa, and it causes histotoxic hypoxemia and respiratory depression by exerting an inhibitory effect on cytochrome oxidase. To evaluate the role of toxicological data in distinguishing between the H2 S blood concentration secondary to lethal poisoning and the endogenous H2 S produced during putrefaction, we compared the postmortem H2 S concentrations of six fatal H2 S poisoning cases (8...
November 16, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27831956/identifying-diffuse-axonal-injury-by-matrix-assisted-laser-desorption-ionization-time-of-flight-a-new-method-for-pathological-observation
#8
Guanheng Ren, Donghua Zou, Ping Huang, Zhengdong Li, Yu Shao, Kaifei Deng, Yijiu Chen, Ningguo Liu
PURPOSE: The aim of this study was to identify the diffuse axonal injury (DAI) of rat through screening out differentially expressed proteins which may represent potential biomarkers by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) imaging mass spectrometry (IMS), which could make a contribution for the research of forensic pathology. METHODS: A total of 15 brainstem sections of rats (10 with and 5 without DAI) were conducted by MALDI-TOF IMS...
December 2016: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/27829755/configuration-of-frontal-sinuses-a-forensic-perspective
#9
Jhansi Lakshmi Suman, Nallusamy Jaisanghar, Somasundaram Elangovan, Nazargi Mahaboob, Balasubramaniyan Senthilkumar, Thukanayakanpalayam Ragunathan Yoithapprabhunath, Kenniyan Kumar Srichinthu
BACKGROUND: Identification of an individual whether living or deceased is of paramount importance in maintaining the integrity of the society. A simple, reliable, and efficacious method always finds a way for easier acceptance and inclusion in any discipline. Likewise, identification of an individual using the radiographic frontal sinus patterns is a simple technique which emphasized to conduct the study with a proven result. OBJECTIVE: The objective of the study is to evaluate the radiographic configurations of frontal sinuses for their uniqueness based on different parameters...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/27826927/microrna-expression-profiling-using-agilent-one-color-microarray
#10
Carmela Dell'Aversana, Cristina Giorgio, Lucia Altucci
MicroRNA (miRNA) expression profiling is an important tool to identify miRNA regulation in physiological or pathological states. This technique has a large number of molecular diagnostic applications, including in cancer, cardiovascular and autoimmune diseases, and forensics. To date, a multitude of high-throughput genomic approaches have been developed. Here, we focus on miRNA expression profiling by microarray using SurePrint technology, providing a description of both the workflow and methods for expression profiling by Agilent One-Color Microarray...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27810588/cyclists-fatalities-forensic-remarks-regarding-335-cases
#11
M Piras, M C Russo, F De Ferrari, A Verzeletti
A retrospective study was carried out on post-mortem examination data regarding 335 cyclists involved in fatal accidents along the period 1983-2012. The following variables were considered: temporal data (year, month, day of the week and hour of the day), circumstances of the accident, vehicles involved, victims' features (sex, age), pathological and toxicological findings, cause of death. Most victims were male (77.62%), with a mean age of 58 years. In most cases vehicles other than only bicycles were involved, more frequently cars, followed by heavy motor vehicles...
November 2016: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/27766573/diagnosis-of-myocardial-ischemia-combining-multiphase-postmortem-ct-angiography-histology-and-postmortem-biochemistry
#12
Jessica Vanhaebost, Kewin Ducrot, Sébastien de Froidmont, Maria Pia Scarpelli, Coraline Egger, Pia Baumann, Gregory Schmit, Silke Grabherr, Cristian Palmiere
PURPOSE: The aim of this study was to assess whether the identification of pathological myocardial enhancement at multiphase postmortem computed tomography angiography was correlated with increased levels of troponin T and I in postmortem serum from femoral blood as well as morphological findings of myocardial ischemia. We further aimed to investigate whether autopsy cases characterized by increased troponin T and I concentrations as well as morphological findings of myocardial ischemia were also characterized by pathological myocardial enhancement at multiphase postmortem computed tomography angiography...
October 20, 2016: La Radiologia Medica
https://www.readbyqxmd.com/read/27763584/-forensic-medical-characteristic-of-the-causes-behind-sudden-death-in-the-young-subjects
#13
Yu I Pigolkin, M A Shilova, E M Kil'dyushov, Eksp Gal'chikov
The objective of the present study was to analyze the causes of sudden death in the general population and in the fraction of the young subjects (below 39 years of age). The results of the original retrospective study were obtained in the course of forensic medical autopsies of the subjects aged below 39 years that had been carried out during a period of 10 years. It was shown that one of the causes behind sudden death among the young subjects is cardiovascular disorders associated with the pre-existing pathological condition in the form of connective tissue dysplasia...
2016: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/27755988/eight-years-of-psychiatric-examination-of-detainees-by-forensic-physicians-in-the-netherlands
#14
Karen E van den Hondel, Anne Linde Saaltink, Peter Paul M Bender
BACKGROUND: Forensic physicians are responsible for first-line medical care of detainees (individuals held in custody) in the police station. The Dutch police law contains a 'duty of care', which gives the police responsibility for the apparent mentally ill and/or confused people they encounter during their work. The police can ask a forensic physician to do a primary psychiatric assessment of any apparent mentally ill detainee. The forensic physician determines if the apparent mentally ill behavior of the detainee is due to a somatic illness, or has a psychiatric cause for which the detainee needs admission to a psychiatric hospital...
October 11, 2016: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/27752779/anterior-wrist-and-medial-malleolus-the-optimal-sites-for-tissue-selection-in-electric-death-through-hand-to-foot-circuit-pathway
#15
Guangtao Xu, Ruibing Su, Junyao Lv, Xiaoping Lai, Xianxian Li, Jiayan Wu, Bo Hu, Long Xu, Ruilin Shen, Jiang Gu, Xiaojun Yu
Specific morphological changes may be absent in some cases of electrocution shocked by the voltage of 220 V or lower. In this study, we attempted to demonstrate that the anterior wrist and medial malleolus were the optimal sites with promising and significant changes in electric death through the hand-to-foot circuit pathway. We established an electric shock rat model and observed histopathologic changes in the anterior wrist and medial malleolus. The results showed that the current intensities in the left anterior wrist and right medial malleolus were remarkably higher than those in the other sites, and the nuclei long/short (L/S) axis ratios of the arterial endotheliocyte and the skeletal muscle cell in these two areas were significantly higher than those in other parts of the body...
October 17, 2016: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/27726795/forensic-phytopathology-a-critical-review
#16
Paul Bayman, Luz M Serrato-Díaz
Forensic phytopathology is the application of plant pathology to legal or criminal matters. It is an emerging field. The existing literature focuses mainly on potential agricultural bioterrorism threats to the United States. Here we try to take a broader view including agricultural bioterrorism, mycoherbicide applications to eradicate plants used for illegal drugs, civil cases involving charges of sale or movement of diseased plants, and mycotoxins. In several of the examples given the evidence is inconclusive, but the examples are no less interesting for that...
August 2016: Microbiology Spectrum
https://www.readbyqxmd.com/read/27702445/forensic-sciences-anthropology-archaeology-pathology-and-international-criminal-justice
#17
Caroline Fournet
No abstract text is available yet for this article.
September 2016: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/27694094/epidemiological-data-and-forensic-aspects-of-road-traffic-fatalities-in-lom%C3%A3-togo
#18
D Tchin, W Atsi, T Hodabalo Tchaa, Kpelao Essossinam, J Yaovii Edèm, K Koffi Amégbor, N-K Gado
We collected 190 forensic records from the only pathology laboratory in Lomé, over the period from January 2010 to December 2014. The sex ratio (M/F) was 4.4 and the decedents' average age 33.4 years. In 43.2% of cases, the accident resulted from a collision between a pedestrian and a motorcycle; excess speed noted in 56.8% of cases. Four principal groups of fatal injuries were observed: polytrauma (136 cases), isolated severe head injury (49 cases), isolated thoracic contusion (3 cases), and abdominal pelvic contusion with perinea trauma (2 cases)...
August 1, 2016: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/27677633/forensic-postmortem-computed-tomography-volumetric-measurement-of-the-heart-and-liver
#19
Lykke Schrøder Jakobsen, Sissel Lundemose, Jytte Banner, Niels Lynnerup, Christina Jacobsen
PURPOSE: The purpose of this study was to investigate the utility of postmortem computed tomography (PMCT) images in estimating organ sizes and to examine the use of the cardiothoracic ratio (CTR). METHODS: We included 45 individuals (19 females), who underwent a medico-legal autopsy. Using the computer software program Mimics(®), we determined in situ heart and liver volumes derived from linear measurements (width, height and depth) on a whole body PMCT-scan, and compared the volumes with ex vivo volumes derived by CT-scan of the eviscerated heart and liver...
September 28, 2016: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/27677096/the-institution-of-a-standardized-investigation-protocol-for-sudden-infant-death-in-the-eastern-metropole-cape-town-south-africa
#20
Johan J Dempers, Jean Coldrey, Elsie H Burger, Vonita Thompson, Shabbir A Wadee, Hein J Odendaal, Mary Ann Sens, Brad B Randall, Rebecca D Folkerth, Hannah C Kinney
The rate for the sudden infant death syndrome (SIDS) in Cape Town, South Africa, is estimated to be among the highest in the world (3.41/1000 live births). In several of these areas, including those of extreme poverty, only sporadic, nonstandardized infant autopsy, and death scene investigation (DSI) occurred. In this report, we detail a feasibility project comprising 18 autopsied infants with sudden and unexpected death whose causes of death were adjudicated according to the 1991 NICHD definitions (SIDS, n = 7; known cause of death, n = 7; and unclassified, n = 4)...
November 2016: Journal of Forensic Sciences
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