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Forensic Pathology

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https://www.readbyqxmd.com/read/28718912/survival-of-atherosclerotic-calcifications-in-skeletonized-material-forensic-and-pathological-implications
#1
Lucie Biehler-Gomez, Annalisa Cappella, Elisa Castoldi, Laurent Martrille, Cristina Cattaneo
Atherosclerosis is a chronic inflammatory disease creating calcifying plaques in the arterial walls. Because its paleopathological diagnosis remains little studied on skeletal remains, its impact on forensic and archeological data is completely underestimated. Here, 24 skeletal remains from the Milano Cemetery Skeletal Collection have been studied to evaluate the chance of atherosclerotic calcification survival, retrieval, and identification. Through direct comparison with a known autopsy collection and literature, the identification and categorization of several types of calcifications were performed...
July 18, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28704795/endocan-concentrations-in-postmortem-serum-vitreous-humor-and-urine-in-victims-of-lethal-hypothermia
#2
Emilienne Descloux, Marc Augsburger, Grzegorz Teresiński, Petr Hejna, Eric Grouzmann, Maria Pia Scarpelli, Tania Hervet, Cristian Palmiere
Endocan is a soluble molecule secreted from vascular endothelial cells of various organs. Its exact function in humans remains to be elucidated, though it has been postulated that increased tissue expression or serum levels of this molecule may be an indicator of endothelial activation and neovascularization. In the realm of forensic pathology, studies pertaining to endothelial activation following exposure to cold exclusively focused on thrombomodulin, a transmembrane protein specific to endothelial cells...
July 4, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28696182/prediction-of-psychiatric-hospitalization-diagnoses-arrests-and-violent-behavior-through-scored-drawings-and-associations
#3
Frank J Dyer
The article presents a completely empirical approach to using drawings and associations as a supplemental tool in forensic psychological assessment. The present system represents a modern alternative to prior theory-driven "projective technique" approaches that have failed to pass scientific scrutiny. Using an archival sample of 252 forensic cases, House-Tree-Person drawing protocols were scored according to preliminary test items developed from published handbooks, academic courses, and workshops on the use of drawings and related associations for assessment...
January 1, 2017: Psychological Reports
https://www.readbyqxmd.com/read/28692478/diagnosis-of-vitality-in-skin-wounds-in-the-ligature-marks-resulting-from-suicide-hanging
#4
Isabel Legaz Pérez, Maria Falcón, M Gimenez, F Martínez Diaz, M D Pérez-Cárceles, E Osuna, D Nuno-Vieira, A Luna
Ascertaining the vital origin of skin wounds is one of the most challenging problems in forensic pathology. The forensic literature describes biomarkers and methods for differentiating vital and postmortem wounds, although no clear conclusions have been reached. The aim of this study was to characterize human vital wounds by analyzing the concentrations of metallic ions and the expression of P-selectin and cathepsin D in skin wounds in the ligature marks in a cohort of suicidal hangings for which vitality was previously demonstrated...
July 7, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28689029/course-constructions-a-case-base-of-forensic-toxicology
#5
Nan Zhou, Yeda Wu, Terry Su, Liyong Zhang, Kun Yin, Da Zheng, Jingjing Zheng, Lei Huang, Qiuping Wu, Jianding Cheng
Forensic toxicology education in China is limited by insufficient teaching methods and resources, resulting in students with adequate theoretical principles but lacking practice experience. Typical cases used as teaching materials vividly represent intoxication and provide students with an opportunity to practice and hone resolving skills. In 2013, the Department of Forensic Pathology at Zhongshan School of Medicine began to construct top-quality courses in forensic toxicology, with its first step, creating a base containing typical cases of intoxication...
June 28, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28686962/forensic-aspects-of-homicides-by-insulin-overdose
#6
Fang Tong, Rongqi Wu, Wen Huang, Yi Yang, Lin Zhang, Biao Zhang, Xin Chen, Xiaohui Tang, Yiwu Zhou
Analysis of homicidal insulin overdose is a challenging task in forensic practice because of the difficulties in toxicological analysis as well as the elusive pathologic changes. We performed a detailed histopathologic examination on four autopsy cases involving insulin homicide, using H&E, immunohistochemistry (IHC) and immunofluorescence assays. Severe reactive astrocyte proliferation was obvious in the white matter of the cerebrum, corpus callosum, cerebellum and brain stem, especially in subcortical regions...
June 20, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28675999/subduing-the-green-eyed-monster-bridging-the-psychopharmacological-and-psychosocial-treatment-perspective-in-understanding-pathological-jealousy
#7
Farah Deena Abdul Samad, Hatta Sidi, Jaya Kumar, Srijit Das, Marhani Midin, Nurul Hazwani Hatta
Human being is not spared from a broad-ranged emotional state, including being jealous. Jealousy has both affective-cognitive and behavioural-evaluative dimension where the person perceives, or experiences a real threat on a valued relationship. As this complex emotion becomes irrational and not amenable to reason, it later transforms into a dangerously 'green-eyed monster'. This perilous situation which is viewed as pathological jealousy is a form of delusion, which is maintained by a fixed and false reasoning in an originally entrusted intimate relationship...
July 4, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28674960/autopsy-histopathology-where-the-prosector-is-not-a-histopathologist-a-proposal
#8
Mohammed Madadin, Rihab Molah, Stephen Cordner
Forensic pathology is a specialty that involves death investigation while clinical forensic medicine is the application of the practice of medicine to the requests of the law in relation to the living. Around the world, there is diverse practice for these two disciplines. The forensic physician or forensic doctor (sometimes, called a forensic pathologist but not a forensic histopathologist) in parts of the world such as continental Europe, the Middle East and India, practice both clinical forensic medicine and forensic pathology...
July 3, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28663329/long-qt-syndrome-and-sudden-unexpected-infant-death
#9
EDITORIAL
Chantal Van Niekerk, Barbara Ströh Van Deventer, Lorraine du Toit-Prinsloo
Long QT syndrome (LQTS) is an inheritable primary electric disease of the heart characterised by abnormally long QT intervals and a propensity to develop atrial and ventricular tachyarrhythmias. It is caused by an inherited channelopathy responsible for sudden cardiac death in individuals with structurally normal hearts. Long QT syndrome can present early in life, and some studies suggest that it may be associated with up to 20% of sudden unexplained infant death (SUID), particularly when associated with external stressors such as asphyxia, which is commonly seen in many infant death scenes...
June 29, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28656955/-mri-diagnostics-of-bone-marrow-oedema-and-its-significance-for-the-forensic-medical-evaluation-of-the-injuries-to-bones-and-articulations
#10
V A Fetisov, K Yu Kulinkovich
The objective of the present study was the analysis of the publications in the literature dealing with radiological methods employed for the diagnostics of injuries to and diseases of the bones and articulations as well as the role of bone marrow oedema in the development of these conditions in the specific context of the problems facing forensic medical expertise. The main results of the domestic and foreign authors concerning MRI-based investigations into the nature of injuries and other pathological changes in bones and articulations during different periods after their development are discussed with the major emphasis placed on diagnostics of bone marrow oedema...
2017: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/28656953/-the-infarction-or-the-traumatic-rupture-of-the-spleen
#11
I A Tolmachev, A N Belykh, A P Bozhchenko, I E Loban, A E Safrai
The clinical observation reported in the present article is of special interest for the forensic medical experts taking into consideration the rare occurrence of infarction of the spleen in the medical legal practice. More comprehensive detailed information about such cases is needed for their thorough in-depth investigation and systematization of the differential diagnostic signs and clinical manifestations of the injury (rupture of the spleen) and pathology of the organ (infarction) for the purpose of the more reliable differentiation between these conditions, creation of the relevant diagnostic database, formulation of more conclusive recommendations, and their better substantiation...
2017: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/28631383/benford-s-law-for-quality-assurance-of-manner-of-death-counts-in-small-and-large-databases
#12
Jeremy Daniels, Samantha-Jo Caetano, Dirk Huyer, Andrew Stephen, John Fernandes, Alice Lytwyn, Fred M Hoppe
To assess if Benford's law, a mathematical law used for quality assurance in accounting, can be applied as a quality assurance measure for the manner of death determination. We examined a regional forensic pathology service's monthly manner of death counts (N = 2352) from 2011 to 2013, and provincial monthly and weekly death counts from 2009 to 2013 (N = 81,831). We tested whether each dataset's leading digit followed Benford's law via the chi-square test. For each database, we assessed whether number 1 was the most common leading digit...
June 20, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28625099/toxicology-in-clinical-laboratories-challenging-times
#13
N W Brown
In recent years, there have been a number of significant developments in toxicology within clinical laboratories, both with the available instrumentation and in the range of compounds abused by the drug using communities. There have also been developments in the regulation of forensic science in the UK which may in time impact clinical toxicology. This review is designed to provide an update of these changes within toxicology to the more general pathology laboratory audience. For detailed information in specific areas, the reader is referred to the references in the text...
July 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28621570/forensic-science-and-forensic-pathology-quality-standards-and-risks
#14
Gillian Tully
No abstract text is available yet for this article.
January 1, 2017: Medico-legal Journal
https://www.readbyqxmd.com/read/28614917/cell-death-associated-ribosomal-rna-cleavage-in-postmortem-tissues-and-its-forensic-applications
#15
Ji Yeon Kim, Yunmi Kim, Hyo Kyeong Cha, Hye Young Lim, Hyungsub Kim, Sooyoung Chung, Juck-Joon Hwang, Seong Hwan Park, Gi Hoon Son
Estimation of postmortem interval (PMI) is a key issue in the field of forensic pathology. With the availability of quantitative analysis of RNA levels in postmortem tissues, several studies have assessed the postmortem degradation of constitutively expressed RNA species to estimate PMI. However, conventional RNA quantification as well as biochemical and physiological changes employed thus far have limitations related to standardization or normalization. The present study focuses on an interesting feature of the subdomains of certain RNA species, in which they are site-specifically cleaved during apoptotic cell death...
June 30, 2017: Molecules and Cells
https://www.readbyqxmd.com/read/28612206/temperature-corrected-postmortem-3-t-mr-quantification-of-histopathological-early-acute-and-chronic-myocardial-infarction-a-feasibility-study
#16
Anders Persson, John Baeckmann, Johan Berge, Christian Jackowski, Marcel Warntjes, Wolf-Dieter Zech
The goal of the present study was to evaluate if quantitative postmortem cardiac 3-T magnetic resonance (QPMCMR) T1 and T2 relaxation times and proton density values of histopathological early acute and chronic myocardial infarction differ to the quantitative values of non-pathologic myocardium and other histopathological age stages of myocardial infarction with regard to varying corpse temperatures. In 60 forensic corpses (25 female, 35 male), a cardiac 3-T MR quantification sequence was performed prior to autopsy and cardiac dissection...
June 13, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28593772/-complications-arising-out-of-insufficient-reporting-of%C3%A2-clinical-data-to-the-pathologist-investigating-placentas
#17
Š Hadravská, M Dubová, P Mukenšnabl, O Daum
OBJECTIVE: To inform gynecologists-obstetricians about the problems associated with pathological examination of placentas, with special regard to the possibility of crucial role of complete and relevant clinical data in establishing the correct pathological diagnosis. DESIGN: Case report and overview of the problems associated with examination of placentas by pathologist. SETTING: Sikl´s Institute of Pathology, Faculty Hospital and Medical Faculty Pilzen of the Charles University in Prague; Biopticka laborator, s...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/28590265/expression-of-kgf-1-and-kgf-2-in-skin-wounds-and-its-application-in-forensic-pathology
#18
Lin Sheng Yu, Xing Biao Li, Yan Yan Fan, Guang Hua Ye, Jun-Li Li, Tong-Tong Fu, Yi Liao, Feng Li
The expression of keratinocyte growth factor-1 (KGF-1) and keratinocyte growth factor-2 (KGF-2) in skin wounds in mice was studied using multiple methods. The dynamic expression of KGF-1 and KGF-2 for antemortem and postmortem injuries as well as the examination of antemortem injuries after death under different temperature and over varying time periods was studied. It demonstrates that skin KGF-1 resulting from an antemortem injury starts to rise at 6 hours, reaches its peak at 1 day, and starts to drop at 5 days...
June 5, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28588157/an-evaluation-of-faculty-wise-teaching-performance-in-a-public-medical-college-of-bangladesh
#19
M K Khan, M R Hassan, S K Saha, M S Basher, S Kabir, A N Naushad
Teaching is a complex and demanding activity that involves Mastery of content, classroom control and techniques of organization and command of teaching skills. Teachers' continuous engagement in learning, skill acquisition and refinement to practice is essential for meeting student learning needs. Medical education is principally centered on the transmission of medical knowledge and assisting medical students to acquire the necessary skills and attitudes associated with medical practice. Evaluation of teaching is important in the teaching-learning process...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28584475/virtopsy-touch-free-autopsy
#20
REVIEW
Raj Kumar Badam, Triekan Sownetha, D B Gandhi Babu, Shefali Waghray, Lavanya Reddy, Komali Garlapati, Sunanda Chavva
The word "autopsy" denotes "to see with own eyes." Autopsy (postmortem) is a process that includes a thorough examination of a corpse noting everything related to anatomization, surface wounds, histological and culture studies. Virtopsy is a term extracted from two words "virtual" and "autopsy." It employs imaging methods that are routinely used in clinical medicine such as computed tomography and magnetic resonance imaging in the field of autopsy, to find the reason for death. Virtopsy is a multi-disciplinary technology that combines forensic medicine and pathology, roentgenology, computer graphics, biomechanics, and physics...
January 2017: Journal of Forensic Dental Sciences
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