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https://www.readbyqxmd.com/read/27914174/mathematical-detection-of-aortic-valve-opening-b-point-in-impedance-cardiography-a-comparison-of-three-popular-algorithms
#1
Javier Rodríguez Árbol, Pandelis Perakakis, Alba Garrido, José Luis Mata, M Carmen Fernández-Santaella, Jaime Vila
The preejection period (PEP) is an index of left ventricle contractility widely used in psychophysiological research. Its computation requires detecting the moment when the aortic valve opens, which coincides with the B point in the first derivative of impedance cardiogram (ICG). Although this operation has been traditionally made via visual inspection, several algorithms based on derivative calculations have been developed to enable an automatic performance of the task. However, despite their popularity, data about their empirical validation are not always available...
December 3, 2016: Psychophysiology
https://www.readbyqxmd.com/read/27913628/kinect-system-in-home-based-cardiovascular-rehabilitation
#2
Ágata Vieira, Joaquim Gabriel, Cristina Melo, Jorge Machado
Cardiovascular diseases lead to a high consumption of financial resources. An important part of the recovery process is the cardiovascular rehabilitation. This study aimed to present a new cardiovascular rehabilitation system to 11 outpatients with coronary artery disease from a Hospital in Porto, Portugal, later collecting their opinions. This system is based on a virtual reality game system, using the Kinect sensor while performing an exercise protocol which is integrated in a home-based cardiovascular rehabilitation programme, with a duration of 6 months and at the maintenance phase...
December 1, 2016: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/27913367/a-new-method-for-self-estimation-of-the-severity-of-obstructive-sleep-apnea-using-easily-available-measurements-and-neural-fuzzy-evaluation-system
#3
Ming-Feng Wu, Wei-Chang Huang, Chia-Feng Juang, Kai-Ming Chang, Chih-Yu Wen, Yu-Hsuan Chen, Ching-Yi Lin, Yi-Chan Chen, Ching-Cheng Lin
This paper proposes a neural fuzzy evaluation system (NFES) with significant variables selected from stepwise regression to predict apnea-hypopnea index (AHI) for evaluating obstructive sleep apnea (OSA). The variables considered are the change statuses of blood pressure (BP) before going to sleep and early in the morning as well as other five easily available measurements (age, body mass index (BMI) etc.) so that users can use the system for self-evaluation of OSA. A total of 150 subjects are reviewed retrospectively and categorized as training (120 subjects) and validation (30 subjects) sets by a five-fold cross validation scheme with stratified sampling based on the OSA severity...
December 1, 2016: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/27913366/deepr-a-convolutional-net-for-medical-records
#4
Phuoc Nguyen, Truyen Tran, Nilmini Wickramasinghe, Svetha Venkatesh
Feature engineering remains a major bottleneck when creating predictive systems from electronic medical records. At present, an important missing element is detecting predictive regular clinical motifs from irregular episodic records. We present Deepr (short for Deep record), a new end-to-end deep learning system that learns to extract features from medical records and predicts future risk automatically. Deepr transforms a record into a sequence of discrete elements separated by coded time gaps and hospital transfers...
December 1, 2016: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/27913348/automatic-refinement-strategies-for-manual-initialization-of-object-trackers
#5
Hao Zhu, Fatih Porikli
Tracking objects across multiple frames is a wellinvestigated problem in computer vision. The majority of the existing algorithms assume an accurate initialization is readily available. However, in many real-life settings, in particular for applications where the video is streaming in real-time, the initialization has to be provided by a human operator. This limitation raises an inevitable uncertainty issue. Here, we first collect a large and new dataset of inputs that consists of more than 20K human initialization clicks, called as HIC, by several subjects under three practical user interface scenarios for the popular TB50 tracking benchmark...
December 1, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/27913346/automatic-design-of-high-sensitivity-color-filter-arrays-with-panchromatic-pixels
#6
Jia Li, Chenyan Bai, Zhouchen Lin, Jian Yu
In most of existing digital cameras, color images have to be reconstructed from raw images which only have one color sensed at each pixel, as their imaging sensors are covered by color filter arrays (CFAs). At each pixel a CFA usually allows only a portion of the light spectrum to pass through and thereby reduces the light sensitivity of pixels. To address this issue, previous works have explored adding panchromatic pixels into CFAs. However, almost all existing methods assign panchromatic pixels empirically, making the designed CFAs prone to aliasing artifacts...
December 1, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/27913343/a-frequency-shift-method-to-measure-shear-wave-attenuation-in-soft-tissues
#7
Simon Bernard, Siavash Kazemirad, Guy Cloutier
In vivo quantification of shear wave attenuation in soft tissues may help to better understand human tissue rheology and lead to new diagnostic strategies. Attenuation is difficult to measure in acoustic radiation force elastography because the shear wave amplitude decreases due to a combination of diffraction and viscous attenuation. Diffraction correction requires assuming a cylindrical wavefront and an isotropic propagation medium, which may not be the case in some applications. In this study, the frequency shift method, used in ultrasound imaging and seismology, was adapted for shear wave attenuation measurement in elastography...
December 1, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27913325/increasing-axial-resolution-of-ultrasonic-imaging-with-a-joint-sparse-representation-model
#8
Junbo Duan, Hui Zhong, Bowen Jing, Siyuan Zhang, Mingxi Wan
The axial resolution of ultrasonic imaging is confined by the temporal width of acoustic pulse generated by the transducer, which has a limited bandwidth. Deconvolution can eliminate this effect and, therefore, improve the resolution. However, most ultrasonic imaging methods perform deconvolution scan line by scan line, and therefore the information embedded within the neighbor scan lines is unexplored, especially for those materials with layered structures such as blood vessels. In this paper, a joint sparse representation model is proposed to increase the axial resolution of ultrasonic imaging...
December 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27913322/automatic-detection-and-classification-of-high-frequency-oscillations-in-depth-eeg-signals
#9
Nisrine Jrad, Amar Kachenoura, Isabelle Merlet, Fabrice Bartolomei, Anca Nica, Arnaud Biraben, Fabrice Wendling
GOAL: Interictal High Frequency Oscillations (HFOs [30-600 Hz]) have proven to be relevant biomarkers in epilepsy. In this paper, four categories of HFOs are considered: Gamma ([30- 80 Hz]), High-Gamma ([80-120 Hz]), Ripples ([120-250 Hz]) and Fast-Ripples ([250-600 Hz]). A universal detector of the four types of HFOs is proposed. It has the advantages of i) classifying HFOs, and thus being robust to inter- and intra-subject variability; ii) rejecting artefacts, thus being specific. METHODS: Gabor atoms are tuned to cover the physiological bands...
November 29, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/27913245/contextual-computing-a-bluetooth-based-approach-for-tracking-healthcare-providers-in-the-emergency-room
#10
Joshua Frisby, Vernon Smith, Stephen Traub, Vimla L Patel
Hospital Emergency Departments (EDs) frequently experience crowding. One of the factors that contributes to this crowding is the "door to doctor time", which is the time from a patient's registration to when the patient is first seen by a physician. This is also one of the Meaningful Use (MU) performance measures that emergency departments report to the Center for Medicare and Medicaid Services (CMS). Current documentation methods for this measure are inaccurate due to the imprecision in manual data collection...
November 29, 2016: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/27913175/automated-cta-based-measurements-for-planning-support-of-minimally-invasive-aortic-valve-replacement-surgery
#11
Mustafa A Elattar, Floortje van Kesteren, Esther M Wiegerinck, Ed Vanbavel, Jan Baan, Riccardo Cocchieri, Bas de Mol, Nils R Planken, Henk A Marquering
Minimally invasive aortic valve replacement (mini-AVR) procedures are a valuable alternative to conventional open heart surgery. Currently, planning of mini-AVR consists of selection of the intercostal space closest to the sinotubular junction on preoperative computer tomography images. We developed an automated algorithm detecting the sinotubular junction (STJ) and intercostal spaces for finding the optimal incision location. The accuracy of the STJ detection was assessed by comparison with manual delineation by measuring the Euclidean distance between the manually and automatically detected points...
November 29, 2016: Medical Engineering & Physics
https://www.readbyqxmd.com/read/27913106/innovations-in-radiotherapy-technology
#12
I J Feain, L Court, J R Palta, S Beddar, P Keall
Many low- and middle-income countries, together with remote and low socioeconomic populations within high-income countries, lack the resources and services to deal with cancer. The challenges in upgrading or introducing the necessary services are enormous, from screening and diagnosis to radiotherapy planning/treatment and quality assurance. There are severe shortages not only in equipment, but also in the capacity to train, recruit and retain staff as well as in their ongoing professional development via effective international peer-review and collaboration...
November 29, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27912979/measuring-performance-in-the-interpretation-of-chest-radiographs-a-pilot-study
#13
Y Chen, J J James, L Dong, A G Gale
AIM: To develop a system to assess the image interpretation performance of radiologists in identifying signs of malignancy on chest radiographs. MATERIALS AND METHODS: A test set of 30 chest radiographs was chosen by an experienced radiologist consisting of 11 normal and 19 abnormal cases. The malignant cases all had biopsy-proven pathology; the normal and benign cases all had at least 2 years of imaging follow-up. Fourteen radiologists with a range of experiences were recruited...
November 29, 2016: Clinical Radiology
https://www.readbyqxmd.com/read/27911905/semi-supervised-feature-transformation-for-tissue-image-classification
#14
Kenji Watanabe, Takumi Kobayashi, Toshikazu Wada
Various systems have been proposed to support biological image analysis, with the intent of decreasing false annotations and reducing the heavy burden on biologists. These systems generally comprise a feature extraction method and a classification method. Task-oriented methods for feature extraction leverage characteristic images for each problem, and they are very effective at improving the classification accuracy. However, it is difficult to utilize such feature extraction methods for versatile task in practice, because few biologists specialize in Computer Vision and/or Pattern Recognition to design the task-oriented methods...
2016: PloS One
https://www.readbyqxmd.com/read/27911348/comparison-between-heart-rate-variability-and-pulse-rate-variability-during-different-sleep-stages-for-sleep-apnea-patients
#15
Shuangyan Liu, Jing Teng, Xianghua Qi, Shoushui Wei, Chengyu Liu
BACKGROUND: The usefulness of heart rate variability (HRV) in the clinical research has been verified in numerous studies. However, it is controversy that using pulse rate variability (PRV) as a surrogate of HRV in different clinical applications. OBJECTIVE: We aimed to investigate whether PRV extracted from finger pulse photoplethysmography (Pleth) signal could substitute HRV from ECG signal during different sleep stages by analyzing the common time-domain, frequency-domain and non-linear indices...
November 25, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/27911322/shape-attributes-of-brain-structures-as-biomarkers-for-alzheimer-s-disease
#16
Tanya Glozman, Justin Solomon, Franco Pestilli, Leonidas Guibas
We describe a fully automatic framework for classification of two types of dementia based on the differences in the shape of brain structures. We consider Alzheimer's disease (AD), mild cognitive impairment of individuals who converted to AD within 18 months (MCIc), and normal controls (NC). Our approach uses statistical learning and a feature space consisting of projection-based shape descriptors, allowing for canonical representation of brain regions. Our framework automatically identifies the structures most affected by the disease...
November 26, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27910948/improved-in-cell-structure-determination-of-proteins-at-near-physiological-concentration
#17
Teppei Ikeya, Tomomi Hanashima, Saori Hosoya, Manato Shimazaki, Shiro Ikeda, Masaki Mishima, Peter Güntert, Yutaka Ito
Investigating three-dimensional (3D) structures of proteins in living cells by in-cell nuclear magnetic resonance (NMR) spectroscopy opens an avenue towards understanding the structural basis of their functions and physical properties under physiological conditions inside cells. In-cell NMR provides data at atomic resolution non-invasively, and has been used to detect protein-protein interactions, thermodynamics of protein stability, the behavior of intrinsically disordered proteins, etc. in cells. However, so far only a single de novo 3D protein structure could be determined based on data derived only from in-cell NMR...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27910898/hydrogen-overproducing-nitrogenases-obtained-by-random-mutagenesis-and-high-throughput-screening
#18
Emma Barahona, Emilio Jiménez-Vicente, Luis M Rubio
When produced biologically, especially by photosynthetic organisms, hydrogen gas (H2) is arguably the cleanest fuel available. An important limitation to the discovery or synthesis of better H2-producing enzymes is the absence of methods for the high-throughput screening of H2 production in biological systems. Here, we re-engineered the natural H2 sensing system of Rhodobacter capsulatus to direct the emission of LacZ-dependent fluorescence in response to nitrogenase-produced H2. A lacZ gene was placed under the control of the hupA H2-inducible promoter in a strain lacking the uptake hydrogenase and the nifH nitrogenase gene...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27910875/an-integrated-modelling-framework-from-cells-to-organism-based-on-a-cohort-of-digital-embryos
#19
Paul Villoutreix, Julien Delile, Barbara Rizzi, Louise Duloquin, Thierry Savy, Paul Bourgine, René Doursat, Nadine Peyriéras
We conducted a quantitative comparison of developing sea urchin embryos based on the analysis of five digital specimens obtained by automatic processing of in toto 3D+ time image data. These measurements served the reconstruction of a prototypical cell lineage tree able to predict the spatiotemporal cellular organisation of a normal sea urchin blastula. The reconstruction was achieved by designing and tuning a multi-level probabilistic model that reproduced embryo-level dynamics from a small number of statistical parameters characterising cell proliferation, cell surface area and cell volume evolution along the cell lineage...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27910619/a-compact-five-port-waveguide-structure-and-its-application-as-a-three-way-power-divider
#20
Letian Guo, Jiawei Li, Tao Ba, Wenhua Huang, Hao Shao
A compact five-port waveguide structure consisting of three rectangular ports, one coaxial port, and one circular waveguide port is proposed. The three rectangular waveguides are uniformly distributed in space at angles of 120°, and the coaxial and circular waveguides are located at the top and bottom, respectively, of the rectangular waveguides. The ideal scattering matrix is derived from the symmetry properties of the structure. If the circular and coaxial ports are matched, then the entire five-port waveguide structure is automatically matched...
November 2016: Review of Scientific Instruments
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