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https://www.readbyqxmd.com/read/28102557/cardiovascular-disease-and-prediabetes-as-complex-illness-people-s-perspectives
#1
Kim van Wissen, Michelle Thunders, Karen Mcbride-Henry, Margaret Ward, Jeremy Krebs, Rachel Page
Cardiovascular disease (CVD) and sustained high blood glucose as prediabetes are an established comorbidity. People's experience in reconciling these long-term conditions requires deeper appreciation if nurses are to more effectively support person-centred care for people who have them. Our analysis explores the initial experience of people admitted to hospital with CVD who then find they also have sustained high blood glucose. Our methodology is informed by the philosophy of Gadamer and applies interpretive description to develop an interpretation of participant experiences...
January 19, 2017: Nursing Inquiry
https://www.readbyqxmd.com/read/28101520/an-observational-study-of-alemtuzumab-following-fingolimod-for-multiple-sclerosis
#2
Mark Willis, Owen Pearson, Zsolt Illes, Tobias Sejbaek, Christian Nielsen, Martin Duddy, Kate Petheram, Caspar van Munster, Joep Killestein, Clas Malmeström, Emma Tallantyre, Neil Robertson
OBJECTIVE: To describe a series of patients with relapsing multiple sclerosis (MS) who experienced significant and unexpected disease activity within the first 12 months after switching from fingolimod to alemtuzumab. METHODS: Patients with relapsing MS treated sequentially with fingolimod then alemtuzumab who experienced significant subsequent disease activity were identified by personal communication with 6 different European neuroscience centers. RESULTS: Nine patients were identified...
March 2017: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/28100465/prevalence-of-masked-hypertension-among-us-adults-with-nonelevated-clinic-blood-pressure
#3
Y Claire Wang, Daichi Shimbo, Paul Muntner, Andrew E Moran, Lawrence R Krakoff, Joseph E Schwartz
Masked hypertension (MHT), defined as nonelevated blood pressure (BP) in the clinic setting and elevated BP assessed by ambulatory monitoring, is associated with increased risk of target organ damage, cardiovascular disease, and mortality. Currently, no estimate of MHT prevalence exists for the general US population. After pooling data from the Masked Hypertension Study (n = 811), a cross-sectional clinical investigation of systematic differences between clinic BP and ambulatory BP (ABP) in a community sample of employed adults in the New York City metropolitan area (2005-2012), and the National Health and Nutrition Examination Survey (NHANES; 2005-2010; n = 9,316), an ongoing nationally representative US survey, we used multiple imputation to impute ABP-defined hypertension status for NHANES participants and estimate MHT prevalence among the 139 million US adults with nonelevated clinic BP, no history of overt cardiovascular disease, and no use of antihypertensive medication...
January 18, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28099397/the-effects-of-attention-problems-on-psychosocial-functioning-in-childhood-brain-tumor-survivors-a-2-year-postcraniospinal-irradiation-follow-up
#4
Yunhye Oh, Hyunjung Seo, Ki Woong Sung, Yoo Sook Joung
OBJECTIVE: To examine the psychosocial outcomes and impact of attention problems in survivors of pediatric brain tumor. STUDY DESIGN: The survivors' cognitive functioning was measured using the Wechsler Intelligence Scale for Children. The Child Behavior Checklist-Attention Problems scale was used to screen for attention problems, and participants were classified as having attention problems (n=15) or normal attention (n=36). Psychosocial functioning was examined with the Korean Personality Rating scale for Children (K-PRC) at precraniospinal radiation and at 2-year follow-up...
January 17, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28099360/aggressive-intramuscular-hemangiomas-in-the-upper-extremity-a-case-report
#5
Hui Lu, Qiang Chen, Hu Yang, Hui Shen
INTRODUCTION: Intramuscular hemangioma (IMH) is a rare congenital soft tissue tumor. Here, we report a case of IMH patient who had undergone several surgeries and other treatments that were all ineffective before he visited us. CLINICAL FINDINGS: This IMH patient was a 16-yearold male who was born with a tumor of unknown size in his right hand and forearm. On physical examination, the tumor and skin flap complex was seen with a size of 14 cm_12 cm in his right hand, and the multiple postoperative scars were shown on his right hand and forearm...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28098082/occupational-health-profile-of-workers-employed-in-the-manufacturing-sector-of-india
#6
REVIEW
Shivali Suri, Ranjan Das
BACKGROUND: The occupational health scenario of workers engaged in the manufacturing sector in India deserves attention for their safety and increasing productivity. We reviewed the status of the manufacturing sector, identified hazards faced by workers, and assessed the existing legislations and healthcare delivery mechanisms. METHODS: From October 2014 to March 2015, we did a literature review by manual search of pre-identified journals, general electronic search, electronic search of dedicated websites/databases and personal communication with experts of occupational health...
September 2016: National Medical Journal of India
https://www.readbyqxmd.com/read/28096664/predictors-of-outcomes-following-reablement-in-community-dwelling-older-adults
#7
Hanne Tuntland, Ingvild Kjeken, Eva Langeland, Bjarte Folkestad, Birgitte Espehaug, Oddvar Førland, Mona Kristin Aaslund
BACKGROUND: Reablement is a rehabilitation intervention for community-dwelling older adults, which has recently been implemented in several countries. Its purpose is to improve functional ability in daily occupations (everyday activities) perceived as important by the older person. Performance and satisfaction with performance in everyday life are the major outcomes of reablement. However, the evidence base concerning which factors predict better outcomes and who receives the greatest benefit in reablement is lacking...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28096279/a-framework-of-comfort-for-practice-an-integrative-review-identifying-the-multiple-influences-on-patients-experience-of-comfort-in-healthcare-settings
#8
REVIEW
Cynthia Wensley, Mari Botti, Ann McKillop, Alan F Merry
PURPOSE: Comfort is central to patient experience but the concept of comfort is poorly defined. This review aims to develop a framework representing patients' complex perspective of comfort to inform practice and guide initiatives to improve the quality of healthcare. DATA SOURCES: CINAHL, MEDLINE Complete, PsycINFO and Google Scholar (November 2016); reference lists of included publications. STUDY SELECTION: Qualitative and theoretical studies advancing knowledge about the concept of comfort in healthcare settings...
January 16, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28094061/vitiligo-like-lesions-occurring-in-patients-receiving-anti-programmed-cell-death-1-therapies-are-clinically-and-biologically-distinct-from-vitiligo
#9
Maiana Larsabal, Aurélie Marti, Clément Jacquemin, Jérôme Rambert, Denis Thiolat, Léa Dousset, Alain Taieb, Caroline Dutriaux, Sorilla Prey, Katia Boniface, Julien Seneschal
BACKGROUND: The use of anti-programmed cell death (PD)-1 therapies in metastatic tumors is associated with cutaneous side effects including vitiligo-like lesions. OBJECTIVE: We sought to characterize clinically and biologically vitiligo-like lesions occurring in patients receiving anti-PD-1 therapies by studying a case series of 8 patients with metastatic tumors and 30 control subjects with vitiligo. METHODS: Eight patients receiving anti-PD-1 therapies with features of vitiligo-like lesions seen in our department were recruited...
January 13, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28093836/incremental-validity-of-weight-suppression-in-predicting-clinical-impairment-in-bulimic-syndromes
#10
Kelsey E Hagan, Kelsey E Clark, Kelsie T Forbush
Research has shown that weight suppression (WS; the difference between a person's highest and current body weight in pounds) is a robust predictor of weight gain and eating-disorder (ED) symptoms among individuals with bulimic syndromes. Given the important prognostic role that WS plays in ED course and outcome, we hypothesized that WS would represent a clinically useful indicator of impairment for bulimic syndromes. We further posited that WS would demonstrate incremental validity above-and-beyond other proposed indicators in explaining clinical impairment in bulimic syndromes...
January 17, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28093370/a-comparison-of-locomotor-therapy-interventions-partial-body-weight-supported-treadmill-lokomat%C3%A2-and-g-eo%C3%A2-training-in-persons-with-traumatic-brain-injury
#11
Alberto Esquenazi, Stella Lee, Amanda Wikoff, Andrew Packel, Theresa Toczylowski, John Feeley
BACKGROUND: Literature in the application of gait training techniques in persons with traumatic brain injury is limited. Current techniques require of multiple staff and are physically demanding. The use of a robotic locomotor training may provide improved training capacity for this population. OBJECTIVE: To examine the impact of three different modes of locomotor therapy on gait velocity and spatiotemporal symmetry using: an end effector robot (G-EO™); a robotic exoskeleton (Lokomat®) and manual assisted partial-body weight supported treadmill training (PBWSTT) in participants with traumatic brain injury...
January 13, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28093280/metronomics-in-the-neoadjuvant-and-adjuvant-treatment-of-breast-cancer
#12
Elisabetta Munzone, Marco Colleoni
The concept of metronomic chemotherapy (MC) has evolved from a descriptive preclinical phenomenon encompassing inhibition of angiogenesis to a clinically validated treatment concept involving multiple potential mechanisms of action. Clinicians are progressively more incline to consider MC as a component of mainstream medical oncology practice in advanced breast cancer. However, more recently MC has been tested even in the adjuvant/neoadjuvant setting, taking the opportunity to obtain tumor specimens and blood samples, in order to identify tumor-specific or patient-specific biomarkers for personalizing treatments...
January 13, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28093262/the-anchor-based-minimal-important-change-mic-based-on-roc-analysis-or-predictive-modeling-may-need-to-be-adjusted-for-the-proportion-of-improved-patients
#13
Berend Terluin, Iris Eekhout, Caroline B Terwee
OBJECTIVES: Patients have their individual minimal important changes (iMICs) as their personal benchmarks to determine whether a perceived health-related quality of life (HRQOL) change constitutes a (minimally) important change for them. We denote the mean iMIC in a group of patients as the "genuine MIC" (gMIC). The aims of this paper are (1) to examine the relationship between the gMIC and the anchor-based minimal important change (MIC), determined by receiver operating characteristics (ROC) analysis or by predictive modeling; (2) to examine the impact of the proportion of improved patients on these MICs; and (3) to explore the possibility to adjust the MIC for the influence of the proportion of improved patients...
January 13, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28092801/the-association-between-personal-income-and-aging-a-population-based-13-year-longitudinal-study
#14
Tzu-Yu Lin, Chia-Yu Chen, Chueh-Yung Tsao, Kuang-Hung Hsu
INTRODUCTION: Population aging is set to increase the elder dependency ratio, causing a rapid increase in healthcare expenditures and financial burden on the government. This study aims to construct an aging score from age-related diseases and to perform longitudinal analyses to examine the association between personal income and aging. METHODS: A total of 86,838 subjects drawn from a community with 384,617 residents in northern Taiwan were examined. Personal income and aging-related diseases were measured from the National Health Insurance database during 1997-2010...
January 9, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28092773/how-does-a-newly-encountered-face-become-familiar-the-effect-of-within-person-variability-on-adults-and-children-s-perception-of-identity
#15
Kristen A Baker, Sarah Laurence, Catherine J Mondloch
Adults and children aged 6years and older easily recognize multiple images of a familiar face, but often perceive two images of an unfamiliar face as belonging to different identities. Here we examined the process by which a newly encountered face becomes familiar, defined as accurate recognition of multiple images that capture natural within-person variability in appearance. In Experiment 1 we examined whether exposure to within-person variability in appearance helps children learn a new face. Children aged 6-13years watched a 10-min video of a woman reading a story; she was filmed on a single day (low variability) or over three days, across which her appearance and filming conditions (e...
January 13, 2017: Cognition
https://www.readbyqxmd.com/read/28092535/super-resolution-person-re-identification-with-semi-coupled-low-rank-discriminant-dictionary-learning
#16
Xiao-Yuan Jing, Xiaoke Zhu, Fei Wu, Ruimin Hu, Xinge You, Yunhong Wang, Hui Feng, Jing-Yu Yang
Person re-identification has been widely studied due to its importance in surveillance and forensics applications. In practice, gallery images are high-resolution (HR) while probe images are usually low-resolution (LR) in the identification scenarios with large variation of illumination, weather or quality of cameras. Person re-identification in this kind of scenarios, which we call super-resolution (SR) person re-identification, has not been well studied. In this paper, we propose a semi-coupled low-rank discriminant dictionary learning (SLD2L) approach for SR person re-identification task...
January 10, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28091843/the-incidence-of-post-colonoscopy-colorectal-cancer-a-retrospective-long-term-cohort-study-using-a-colonoscopy-database
#17
Ayako Nakada, Ryota Niikura, Atsuo Yamada, Shuntaro Yoshida, Yoshihiro Hirata, Kazuhiko Koike
PURPOSE: The cumulative incidence of post-colonoscopy colorectal cancer remains unclear. Our aims were to estimate the incidence of and identify risk factors associated with post-colonoscopy colorectal cancer. METHODS: We conducted a retrospective cohort study using the colonoscopy database of the Department of Gastroenterology, the University of Tokyo Hospital Records from1995-2012. A cohort of 2544 patients, who received multiple colonoscopies without colorectal cancer findings at first colonoscopy, was selected...
January 14, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28090687/prevalence-of-psychotropic-medication-use-and-association-with-challenging-behaviour-in-adults-with-an-intellectual-disability-a-total-population-study
#18
D L Bowring, V Totsika, R P Hastings, S Toogood, M McMahon
BACKGROUND: There is a high prevalence of psychotropic medication use in adults with Intellectual Disabilities (ID), often in the absence of psychiatric disorder, also associated with challenging behaviour. Previous research has focused on specific sample frames or data from primary care providers. There is also a lack of consistency in the definition of challenging behaviour used. METHODS: We adopted a total population sampling method. Medication data on 265 adults with ID were classified according to the Anatomical Therapeutic Chemical classification system...
January 16, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/28089620/the-use-of-information-theory-for-the-evaluation-of-biomarkers-of-aging-and-physiological-age
#19
David Blokh, Ilia Stambler
The present work explores the application of information theoretical measures, such as entropy and normalized mutual information, for research of biomarkers of aging. The use of information theory affords unique methodological advantages for the study of aging processes, as it allows evaluating non-linear relations between biological parameters, providing the precise quantitative strength of those relations, both for individual and multiple parameters, showing cumulative or synergistic effect. Here we illustrate those capabilities utilizing a dataset on heart disease, including diagnostic parameters routinely available to physicians...
January 12, 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/28088506/linguistic-indicators-of-pain-catastrophizing-in-patients-with-chronic-musculoskeletal-pain
#20
Doerte U Junghaenel, Stefan Schneider, Joan E Broderick
: The present study examined markers of pain catastrophizing in the word use of patients with chronic pain. Patients (n = 71) completed the Pain Catastrophizing Scale and wrote about their life with pain. Quantitative word count analysis examined whether the essays contained linguistic indicators of catastrophizing. Bivariate correlations showed that catastrophizing was associated with greater use of first person singular pronouns, such as "I" (r = .27, p≤ .05) and pronouns referencing other people (r = 28, p≤ ...
January 11, 2017: Journal of Pain: Official Journal of the American Pain Society
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