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epiretinal membrane

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https://www.readbyqxmd.com/read/28207608/effects-of-internal-limiting-membrane-peeling-combined-with-removal-of-idiopathic-epiretinal-membrane-a-systematic-review-of-literature-and-meta-analysis
#1
Kunihiro Azuma, Takashi Ueta, Shuichiro Eguchi, Makoto Aihara
PURPOSE: To evaluate the effects on postoperative prognosis of internal limiting membrane (ILM) peeling in conjunction with removal of idiopathic epiretinal membranes (ERMs). METHODS: MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), and EMBASE were systematically searched for studies that compared ILM peeling with no ILM peeling in surgery to remove idiopathic ERM. Outcome measures were best-corrected visual acuity, central macular thickness, and ERM recurrence...
February 15, 2017: Retina
https://www.readbyqxmd.com/read/28196052/association-between-tangential-contraction-and-early-vision-loss-in-idiopathic-epiretinal-membrane
#2
Seung Min Lee, Kang Yeun Pak, Han Jo Kwon, Sung Who Park, Ji Eun Lee, Ik Soo Byon
PURPOSE: To investigate the clinical features associated with early visual loss in patients with idiopathic epiretinal membrane. METHODS: Patients with idiopathic epiretinal membrane with visual acuity of ≥20/40, intact ellipsoid zone, and follow-up duration of at least 24 months were included in this retrospective age-matched control study. The disk-fovea-vascular (DFV) distance, central macular thickness, membrane configuration, and ellipsoid zone were assessed using fundus photography and spectral domain optical coherence tomography...
February 10, 2017: Retina
https://www.readbyqxmd.com/read/28195624/spontaneous-closure-of-full-thickness-macular-hole-with-epiretinal-membrane-in-vitrectomized-eyes-case-series-and-review-of-literature
#3
Wenlan Zhang, Dilraj S Grewal, Glenn J Jaffe, Tamer H Mahmoud, Sharon Fekrat
The authors describe three vitrectomized eyes that each subsequently developed a full-thickness macular hole (FTMH) that then spontaneously closed and summarize the current literature reporting these rare events. Clinical history, imaging, and course of three patients were reviewed and compiled. All three cases in this series developed a FTMH less than 7 months following vitrectomy (for epiretinal membrane [ERM], n = 1) and retinal detachment (n = 2) that demonstrated spontaneous resolution within 2 months of symptom onset, without intervention...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195614/omega-sign-a-distinct-optical-coherence-tomography-finding-in-macular-combined-hamartoma-of-retina-and-retinal-pigment-epithelium
#4
Vinod Kumar, Rohan Chawla, Koushik Tripathy
BACKGROUND AND OBJECTIVE: To report a distinct optical coherence tomography (OCT) appearance of macular combined hamartoma of retina and retinal pigment epithelium (CHRRPE). PATIENTS AND METHODS: This is a retrospective case series of four eyes of four patients with macular CHRRPE who were assessed with the help of color fundus photographs, swept-source OCT (SS-OCT), and fundus fluorescein angiography wherever required. RESULTS: All four patients presented with decreased visual acuity...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28187469/-intraoperative-optical-coherence-tomography-an-overview-of-current-clinical-data-for-the-application-in-the-anterior-and-posterior-segments
#5
A J Augustin
Intraoperative optical coherence tomography (iOCT) represents another milestone in ocular imaging technologies. Now, for the first time, high resolution OCT images are available not only pre- or postoperatively, but also intraoperatively. In recent years, there have been significant advances in iOCT technology - from hand-held probes and mounted systems towards iOCT systems which are fully integrated into the surgical microscope and which provide seamless integration into the workflow. These systems offer high-resolution, intraoperative OCT scans in real-time and provide additional information on microstructures of the retina or the cornea...
February 10, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28171859/comparison-of-55%C3%A2-wide-field-spectral-domain-optical-coherence-tomography-and-conventional-30%C3%A2-optical-coherence-tomography-for-the-assessment-of-diabetic-macular-edema
#6
Marion R Munk, Joel Lincke, Helena Giannakaki-Zimmermann, Andreas Ebneter, Sebastian Wolf, Martin S Zinkernagel
PURPOSE: To compare conventional 30° spectral domain optical coherence tomography (SD-OCT) with 55° wide-field SD-OCT for the assessment of diabetic macular edema (DME). METHODS: This study included 50 DME patients. Both 55° and 30° SD-OCT was conducted. Two readers evaluated scans according to a standardized grading protocol. Intergrader agreement as well as agreement between 30° and 55° SD-OCT were assessed. RESULTS: Intergrader agreement (κ) was strong and ranged from 0...
February 8, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28169069/difficulties-in-the-management-of-retinal-capillary-haemangiomas-associated-with-von-hippel-lindau-disease
#7
M Pastor-Montoro, N Hurtado-Montalbán, J A Martínez-Morales, M P Villegas-Pérez
CLINICAL CASE: A 29-year-old female with bilateral retinal capillary haemangiomas (RCH). A genetic analysis was carried out due to the suspicion of von Hippel-Lindau (VHL) disease, with negative results on 2occasions. There was progression of the RCH in the left eye, leading to a macular epiretinal membrane. The patient was treated with laser, intravitreal ranibizumab, and vitrectomy. Finally, a third genetic test detected a de novo mutation in the VHL gene, and led to the genetic diagnosis...
February 3, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28160248/gas-tamponade-for-retinectomy-in-pvr-related-retinal-detachments-a-retrospective-study
#8
Vasileios T Papastavrou, Irini Chatziralli, Dominic McHugh
INTRODUCTION: The purpose of the study was to evaluate the anatomical and functional results in patients with proliferative vitreoretinopathy (PVR) treated with retinectomy and perfluoro-octane gas (C3F8) as a tamponade agent. METHODS: 12 patients with inferior and anterior complicated PVR-related retinal detachment, who were treated with retinectomy, where C3F8 was used as the tamponade agent were examined. Primary outcome was the anatomical success, while visual acuity, existence of an epiretinal membrane (ERM) and intraocular pressure (IOP) postoperatively were secondary outcomes...
February 3, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28151841/visualization-of-macular-pucker-by-multicolor-scanning-laser-imaging
#9
Ilkay Kilic Muftuoglu, Dirk-Uwe Bartsch, Giulio Barteselli, Raouf Gaber, Joseph Nezgoda, William R Freeman
PURPOSE: To compare the visualization of the epiretinal membrane (ERM) using multicolor imaging (MCI) (Heidelberg Engineering, Carlsbad, CA) and conventional white light flood color fundus photography (FP) (Topcon). METHODS: The paired images of patients with ERM who underwent same-day MCI and FP examinations were reviewed. Visibility of the ERM was graded using a scale (0: not visible, 1: barely visible, and 2: clearly visible) by masked readers, and surface folds were counted to quantify the membrane visibility for each method...
February 1, 2017: Retina
https://www.readbyqxmd.com/read/28145973/optical-coherence-tomography-findings-in-cytomegalovirus-retinitis-a-longitudinal-study
#10
Alessandro Invernizzi, Aniruddha Agarwal, Vittoria Ravera, Marta Oldani, Giovanni Staurenghi, Francesco Viola
PURPOSE: To evaluate the vitreal, retinal, and choroidal features using spectral domain optical coherence tomography (SD-OCT) in eyes affected by cytomegalovirus (CMV) retinitis. METHODS: Patients diagnosed with either active or inactive CMV retinitis were included in the study. Complete ophthalmic examination, serial color fundus photography, and SD-OCT (with and without enhanced depth imaging function) were performed for all the subjects at baseline and follow-up visits...
January 31, 2017: Retina
https://www.readbyqxmd.com/read/28138811/pars-plana-vitrectomy-with-360%C3%A2-versus-localized-laser-retinopexy-in-the-management-of-retinal-detachment-with-undetected-breaks-intraoperatively-a-retrospective-comparative-interventional-study
#11
Chuandi Zhou, Zhi Zheng, Qinghua Qiu
The purpose of this study is to compare the efficacy of intraoperative 360° and localized laser retinopexy in 23-gauge pars plana vitrectomy (PPV) for rhegmatogenous retinal detachments (RRD) with undetected retinal breaks intraoperatively. This is a retrospective, comparative, interventional study. Medical records of 48 consecutive eyes with RRD of intraoperative undetected retinal breaks were reviewed. Nineteen patients (group I) received 360° laser retinopexy in PPV, while the remaining 29 patients (group II) underwent localized laser retinopexy...
January 30, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28134963/gli1-expression-in-human-epiretinal-membranes
#12
Sohee Jeon, Jiwon Baek, Won Ki Lee
Purpose: We evaluate the expression of Gli1 in human epiretinal membranes (ERM) and correlate this with clinical data. Methods: We prospectively recruited patients with ERM. A total of 33 human ERM specimens were immunolabeled with anti-Gli1 antibody and the number of total cells/hyperfield (HF), Gli1(+) cells/HF, and the percentage of Gli1(+) cells/total cells were calculated. We evaluated the interrelationship of cellular properties and clinical findings, such as presence of diabetic retinopathy (DR), retinal breaks, intraocular inflammation, central foveal thickness, maximal retinal thickness, retinal contraction, lamellar holes, pseudoholes, the attenuation or absence of an inner segment/outer segment (IS/OS) junction/external limiting membrane (ELM), cystic changes, and paravascular inner retinal defects...
January 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28125840/association-of-high-mobility-group-box-1-with-th-cell-related-cytokines-in-the-vitreous-of-ocular-sarcoidosis-patients
#13
Masaru Takeuchi, Manzo Taguchi, Tomohito Sato, Kyoko Karasawa, Yutaka Sakurai, Kohzou Harimoto, Masataka Ito
Purpose: High-mobility group box-1 (HMGB1) is a nonhistone DNA-binding nuclear protein released from necrotic cells, which is also secreted by activated leukocytes and acts as a primary proinflammatory cytokine. In this study, we compared vitreous HMGB1 levels in ocular sarcoidosis with those in noninflammatory vitreoretinal diseases and evaluated its association with Th cell-related and proinflammatory cytokines. Methods: The study group consisted of 24 patients with ocular sarcoidosis...
January 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28124146/aniseikonia-in-various-retinal-disorders
#14
Fumiki Okamoto, Yoshimi Sugiura, Yoshifumi Okamoto, Takahiro Hiraoka, Tetsuro Oshika
PURPOSE: The purpose was to quantify and compare the severity of aniseikonia in patients undergoing vitrectomy for various retinal disorders. METHODS: We studied 357 patients with retinal disorders including epiretinal membrane (ERM), macular hole (MH), cystoid macular edema with branch / central retinal vein occlusion (BRVO-CME / CRVO-CME), diabetic macular edema (DME), macula-off rhegmatogenous retinal detachment (M-off RD), and macula-on RD (M-on RD) as well as 31 normal controls...
January 25, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28121212/macular-hole-in-stargardt-disease-clinical-and-ultra-structural-observation
#15
Stanislao Rizzo, Dario Pasquale Mucciolo, Daniela Bacherini, Vittoria Murro, Lorenzo Vannozzi, Gianni Virgili, Daniele Bani, Andrea Sodi
PURPOSE: To report for the first time a case report of a Stargardt disease patient who developed a macular hole (MH) which was treated with a surgical approach. METHOD: Case report. RESULTS: After vitrectomy a complete closure of the MH was obtained and the best-corrected visual acuity remained stable. No complications were reported after one year of follow-up. An ultra-structural examination of the removed internal limiting membrane (ILM) and epiretinal membrane (ERM) was carried out under electron microscopy...
January 25, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/28119290/longitudinal-study-of-retinal-status-using-optical-coherence-tomography-after-acute-onset-endophthalmitis-following-cataract-surgery
#16
Thierry Zhou, Florent Aptel, Alain M Bron, Pierre-Loïc Cornut, Karine Palombi, Gilles Thuret, Frédéric Rouberol, Catherine Creuzot-Garcher, Christophe Chiquet
PURPOSE: To analyse the macula imaged with optical coherence tomography (OCT) in patients treated for acute postcataract endophthalmitis. METHODS: Patients presenting with acute postcataract endophthalmitis were included in this observational and multicentre study from January 2008 to December 2011. We recorded the following OCT data at the 3, 6 and 12-month visits: the central macular thickness, the perifoveal macular thickness, the central foveal point thickness and abnormalities of the outer retina, the macula and vitreoretinal interface...
January 24, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28112568/vitrectomy-for-epiretinal-membranes-and-macular-holes-in-uveitis-patients
#17
Sara V Branson, Brendan R McClafferty, Shree K Kurup
PURPOSE: Macular pathology, including macular holes (MHs), epiretinal membranes (ERMs), and macular edema, is a cause of irreversible vision loss in the setting of uveitis. Medical management involves corticosteroids, immunomodulatory medications, and biologics to control inflammation. Pars plana vitrectomy (PPV) has been suggested as a therapy for uveitis, with reports of reduced inflammation and decreased dependence on medication postoperatively. Currently, PPV is reserved for retinal detachments, vitreous opacities, and ERMs, causing vitreomacular traction...
January 23, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28102455/soluble-form-of-lr11-is-highly-increased-in-the-vitreous-fluids-of-patients-with-idiopathic-epiretinal-membrane
#18
Ryuya Hashimoto, Meizi Jiang, Tomoaki Shiba, Nobuyuki Hiruta, Mao Takahashi, Morihiro Higashi, Yuichi Hori, Hideaki Bujo, Takatoshi Maeno
PURPOSE: LR11 (also called SorLA or SORL1) is a migration regulator of adherent cells with the immature proliferative phenotype. The present study investigated the clinical and pathological involvement of the soluble form of LR11 (sLR11) in the idiopathic epiretinal membrane (iERM). METHODS: The subjects were 51 patients with iERM (24 cellophane macular reflex (CMR) and 27 preretinal macular fibrosis (PMF)) and 45 patients with macular holes as age and sex-matched controls...
January 19, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28098728/peripapillary-retinal-nerve-fiber-thickness-changes-after-vitrectomy-for-epiretinal-membrane-in-eyes-with-and-without-vitreous-detachment
#19
Cesare Mariotti, Michele Nicolai, Antonio Longo, Francesca Viti, Elisa Bambini, Andrea Saitta, Vittorio Pirani, Emanuele Orsini, Daniela Baruffa, Michele Reibaldi
PURPOSE: To compare the changes in postoperative peripapillary retinal nerve fiber layer (p-RNFL) thickness after vitrectomy for epiretinal membrane in eyes with preexisting posterior vitreous detachment (PVD) and eyes with surgically induced PVD. METHODS: This study included consecutive patients who underwent 25-gauge vitrectomy for epiretinal membrane. Eyes were divided, according to intraoperative PVD status, into a preexisting PVD group and surgically induced PVD group...
January 16, 2017: Retina
https://www.readbyqxmd.com/read/28098725/how-vitreomacular-interface-modifies-the-efficacy-of-anti-vegf-therapy-for-myopic-choroidal-neovascularization
#20
Pierluigi Iacono, Maurizio Battaglia Parodi, Lorenzo Iuliano, Francesco Bandello
PURPOSE: To evaluate the efficacy of intravitreal ranibizumab in the treatment of myopic choroidal neovascularization (mCNV) complicated by vitreoretinal interface alterations. METHODS: Thirty-two patients affected by mCNV and concurrent vitreoretinal interface disorders, including macular epiretinal membrane (18 patients), lamellar macular hole (4 patients), full-thickness macular hole (1 patient), broad/focal vitreomacular traction (3 patients), broad/focal vitreomacular adhesion (4 patients), and myopic foveoschisis (2 patients), were enrolled in a prospective study...
January 16, 2017: Retina
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