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epiretinal membrane

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https://www.readbyqxmd.com/read/28102455/soluble-form-of-lr11-is-highly-increased-in-the-vitreous-fluids-of-patients-with-idiopathic-epiretinal-membrane
#1
Ryuya Hashimoto, Meizi Jiang, Tomoaki Shiba, Nobuyuki Hiruta, Mao Takahashi, Morihiro Higashi, Yuichi Hori, Hideaki Bujo, Takatoshi Maeno
PURPOSE: LR11 (also called SorLA or SORL1) is a migration regulator of adherent cells with the immature proliferative phenotype. The present study investigated the clinical and pathological involvement of the soluble form of LR11 (sLR11) in the idiopathic epiretinal membrane (iERM). METHODS: The subjects were 51 patients with iERM (24 cellophane macular reflex (CMR) and 27 preretinal macular fibrosis (PMF)) and 45 patients with macular holes as age and sex-matched controls...
January 19, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28098728/peripapillary-retinal-nerve-fiber-thickness-changes-after-vitrectomy-for-epiretinal-membrane-in-eyes-with-and-without-vitreous-detachment
#2
Cesare Mariotti, Michele Nicolai, Antonio Longo, Francesca Viti, Elisa Bambini, Andrea Saitta, Vittorio Pirani, Emanuele Orsini, Daniela Baruffa, Michele Reibaldi
PURPOSE: To compare the changes in postoperative peripapillary retinal nerve fiber layer (p-RNFL) thickness after vitrectomy for epiretinal membrane in eyes with preexisting posterior vitreous detachment (PVD) and eyes with surgically induced PVD. METHODS: This study included consecutive patients who underwent 25-gauge vitrectomy for epiretinal membrane. Eyes were divided, according to intraoperative PVD status, into a preexisting PVD group and surgically induced PVD group...
January 16, 2017: Retina
https://www.readbyqxmd.com/read/28098725/how-vitreomacular-interface-modifies-the-efficacy-of-anti-vegf-therapy-for-myopic-choroidal-neovascularization
#3
Pierluigi Iacono, Maurizio Battaglia Parodi, Lorenzo Iuliano, Francesco Bandello
PURPOSE: To evaluate the efficacy of intravitreal ranibizumab in the treatment of myopic choroidal neovascularization (mCNV) complicated by vitreoretinal interface alterations. METHODS: Thirty-two patients affected by mCNV and concurrent vitreoretinal interface disorders, including macular epiretinal membrane (18 patients), lamellar macular hole (4 patients), full-thickness macular hole (1 patient), broad/focal vitreomacular traction (3 patients), broad/focal vitreomacular adhesion (4 patients), and myopic foveoschisis (2 patients), were enrolled in a prospective study...
January 16, 2017: Retina
https://www.readbyqxmd.com/read/28098723/assessment-of-the-internal-limiting-membrane-status-when-a-macular-epiretinal-membrane-is-removed-in-a-prospective-study
#4
Daniel Vila Solà, Cristofer Nienow, Ignasi Jürgens
PURPOSE: To describe the presence and integrity of the internal limiting membrane (ILM) after removal of the macular epiretinal membrane (ERM) and to investigate the accuracy of tissue identification using surgical dyes when compared to histopathology results. METHODS: Patients with idiopathic ERM were enrolled in a prospective study and randomized to one of two surgical techniques. In one (Group M), only the ERM was deliberately removed and in the other (Group L) the ILM was also removed...
January 16, 2017: Retina
https://www.readbyqxmd.com/read/28096551/the-natural-evolution-of-idiophatic-epimacular-membrane
#5
Libor Hejsek, Alexandr Stepanov, Alena Dohnalova, Tereza Rehakova, Nada Jiraskova
BACKGROUND AND AIMS: Epiretinal membrane (ERM) refers to a semi-translucent tissue layer found on the inner surface of the retina especially in older people. Surgical treatment remains controversial, optimal timing for such treatment is difficult to determine and data on the natural evolution of this disorder are limited. In this study we evaluated the natural course of idiopathic epimacular membrane in 49 patients (53 eyes). MATERIALS AND METHODS: Retrospective evaluation of a group of 49 patients (53 eyes) with idiopathic epimacular membrane confirmed by biomicroscopy, photography and optical coherence tomography (OCT)...
January 13, 2017: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/28089219/prognostic-factors-of-epiretinal-membranes-a-systematic-review
#6
REVIEW
A I M Miguel, A Legris
INTRODUCTION: Epiretinal membranes (ERM) have been increasingly characterized with the advent of new optical coherence tomographies (OCTs). We intended to perform a systematic review regarding prognostic factors (PF) of ERM after surgery. MATERIALS AND METHODS: Systematic review of electronic databases was performed (last date of search was 10 August 2015): Medline, Scopus, Google Scholar, clinicaltrials.gov and current controlled trials. Search queries included: "membrane", "pucker", "prognosis", "prognostic", "epiretinal", "épirétinienne"...
January 11, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28076563/influence-of-the-epiretinal-membrane-on-ranibizumab-therapy-outcomes-in-patients-with-diabetic-macular-edema
#7
Nimet Yesim Ercalik, Serhat Imamoglu, Esra Turkseven Kumral, Nursal Melda Yenerel, Handan Bardak, Yavuz Bardak
Purpose: To investigate the influence of the epiretinal membrane (ERM) on intravitreal ranibizumab (IVR) therapy for diabetic macular edema (DME). Methods: This retrospective study included 56 eyes of 48 patients with DME divided into two groups: the DME with ERM (study) and only DME (control) groups. Changes in the central macular thickness (CMT) and best-corrected visual acuity (BCVA) were evaluated. Results: In the study group, although the CMT was significantly reduced following the first injection (p<0...
November 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28045788/staining-assisted-removal-of-silicone-oil-for-the-identification-of-subclinical-proliferative-vitreoretinopathy
#8
Stanislao Rizzo, Francesco Barca, Francesco Faraldi, Tomasso Caporossi, Gianni Virgili
PURPOSE: Retinal detachment is a frequent complication after removal of silicone oil (ROSO). A retrospective study was conducted to determine whether staining-assisted removal of silicone oil (st-ROSO) allowed better identification and removal of proliferative vitreoretinopathy (PVR) processes compared with a conventional removal of silicone oil technique. METHODS: All individuals underwent pars plana vitrectomy (PPV) and silicone oil fill-in for complicated retinal detachments...
December 30, 2016: Retina
https://www.readbyqxmd.com/read/28045374/the-role-of-internal-limiting-membrane-peeling-in-epiretinal-membrane-surgery-a-randomised-controlled-trial
#9
Paris Tranos, Stavrenia Koukoula, Davic G Charteris, Georgia Perganda, Athanasios Vakalis, Solon Asteriadis, Ilias Georgalas, Petros Petrou
PURPOSE: To compare the anatomical and functional outcomes after primary idiopathic epiretinal membrane (ERM) peeling with or without internal limiting membrane (ILM) peeling. DESIGN: A two-centre randomised, controlled clinical trial with 12 months of follow-up. METHODS: One hundred and two eyes of 102 patients were included in the analysis and were randomised into two groups (ILM peeling (P) and non-ILM peeling (NP) group). Inclusion criteria were: Idiopathic ERM confirmed on optical coherence tomography, age ≥18 years, binocular distortion, best-corrected visual acuity (BCVA) ≤90 ETDRS letters, intraocular pressure ≤23 mm Hg and informed consent...
October 7, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28043309/visual-and-anatomical-outcomes-following-idiopathic-macular-epiretinal-membrane-surgery
#10
Bashiran Shahzadi, Syed Fawad Rizvi, Kanwal Latif, Faisal Murtaza, Saliha Naz
OBJECTIVE: To assess the visual and anatomical outcomes following idiopathic macular epiretinal membrane (IERM) surgery. STUDY DESIGN: Case series. PLACE AND DURATION OF STUDY: Layton Rehmatulla Benevolent Trust (L.R.B.T), Free Base Eye Hospital, Karachi, from January 2015 to June 2016. METHODOLOGY: Thirty eyes of thirty patients affected with idiopathic macular epiretinal membrane stage 2 were enrolled in this study...
December 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28009345/the-role-of-membrane-inner-retina-adherence-in-predicting-simultaneous-internal-limiting-membrane-peeling-during-idiopathic-epiretinal-membrane-surgery
#11
P Tranos, L Wickham, N Dervenis, A Vakalis, S Asteriades, P Stavrakas
PurposeTo correlate the frequency and extent of simultaneous inadvertent internal limiting membrane (ILM) peeling during idiopathic epiretinal membrane (ERM) removal with characteristics of ERM adherence demonstrated on pre-operative spectral domain optical coherence tomography (SD-OCT).Patients and methodsThis is a prospective, observational, case series of patients undergoing pars plana vitrectomy for idiopathic ERM. Inner retina-ERM adhesion was categorized as focal, broad or complete in five anatomic locations at macular area based on preoperative SD-OCT findings...
December 23, 2016: Eye
https://www.readbyqxmd.com/read/28005718/proportion-of-patients-with-macular-hole-surgery-who-would-have-been-favorable-ocriplasmin-candidates-a-retrospective-analysis
#12
Khurram Chaudhary, Michael Y K Mak, Robert Gizicki, Rajeev H Muni, David T Wong, Filiberto Altomare, Alan R Berger
PURPOSE: To identify favorable ocriplasmin candidates from a cohort of idiopathic full thickness macular hole surgery patients. METHODS: The records of patients with full thickness macular hole who underwent pars plana vitrectomy surgery between 2011 and 2015 were reviewed. Clinical data collected included patient demographics, pre- and post-operative Snellen visual acuity, optical coherence tomography findings, and lens status. The authors defined "favorable" ocriplasmin candidates as patients with focal vitreomacular traction, no epiretinal membrane, and hole size ≤400 μm...
January 2017: Retina
https://www.readbyqxmd.com/read/28002284/outcomes-of-anti-vegf-therapy-in-choroidal-neovascularization-after-macular-surgery
#13
Duc Anh Hua, Antonio M Casella, Maria H Berrocal, Dennis Han, Rayan A Alshareef, Hugo Quiroz-Mercado, J Fernando Arevalo, Jay Chhablani
PURPOSE: To report treatment outcomes of anti-vascular endothelial growth factor (VEGF) therapy in choroidal neovascularization (CNV) presenting after macular surgery. METHODS: Retrospective analysis of 7 eyes of 7 patients, who were diagnosed to have CNV after macular surgery and were treated with anti-vascular endothelial growth factor therapy. Collected data included demographic details; history of present illness; surgical procedure; and clinical examination including visual acuity at presentation and follow-up with imaging and management...
December 20, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27993592/insights-into-epiretinal-membranes-presence-of-ectopic-inner-foveal-layers-and-a-new-optical-coherence-tomography-staging-scheme
#14
Andrea Govetto, Robert A Lalane, David Sarraf, Marta S Figueroa, Jean Pierre Hubschman
PURPOSE: To describe the presence of continuous ectopic inner foveal layers associated with epiretinal membranes (ERMs) and to present a new optical coherence tomography (OCT) staging system of ERMs. DESIGN: Retrospective multicenter observational case series. METHODS: Clinical charts and Spectral-Domain OCT images of 194 eyes of 172 consecutive patients diagnosed with ERMs were reviewed and analyzed. RESULTS: The presence of continuous ectopic inner foveal layers was identified in 63 out of 194 eyes (32...
December 16, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27992872/long-term-anatomical-and-functional-outcomes-after-combined-cataract-and-idiopathic-epiretinal-membrane-surgery
#15
Yann Kauffmann, Jean-Christophe Ramel, Rodica Isaico, Aurélie De Lazzer, Alain M Bron, Catherine Creuzot-Garcher
PURPOSE: To describe the 2-year functional and anatomical outcomes in patients operated on for combined cataract and idiopathic epiretinal membrane (ERM) and to study the relationship between best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT) throughout the follow-up. METHODS: This retrospective observational case series included 72 eyes operated on for combined cataract and idiopathic ERM. They were followed with clinical and SD-OCT examinations preoperatively and 1, 6, 12, and 24 months after surgery...
December 20, 2016: Ophthalmic Research
https://www.readbyqxmd.com/read/27992520/surgical-outcome-of-idiopathic-epiretinal-membranes-with-intraretinal-cystic-spaces
#16
Yusuke Shiode, Yuki Morizane, Shinji Toshima, Shuhei Kimura, Fumiaki Kumase, Mio Hosokawa, Masayuki Hirano, Shinichiro Doi, Kosuke Takahashi, Mika Hosogi, Atsushi Fujiwara, Fumio Shiraga
OBJECTIVE: To investigate the occurrence ratio, localization, and surgical outcomes of intraretinal cystic spaces in idiopathic epiretinal membranes (ERMs). METHODS: We retrospectively reviewed the charts of 432 eyes of 398 consecutive patients with idiopathic ERM who underwent vitrectomy and ERM peeling from January 2012 to September 2015. We selected cases with intraretinal cystic space prior to surgery, detected by spectral-domain optical coherence tomography...
2016: PloS One
https://www.readbyqxmd.com/read/27982212/evaluation-of-inner-segment-outer-segment-junctions-in-different-types-of-epiretinal-membranes
#17
Rukiye Aydın, Eyyup Karahan, Mahmut Kaya, Taylan Ozturk, Kubra Serefoglu Cabuk, Nilufer Kocak, Suleyman Kaynak
Purpose: This study was conducted to evaluate the relationships of inner/outer segment (IS/OS) junction disruption, macular thickness, and epiretinal membrane (ERM) grade with best-corrected visual acuity (BCVA), as well as the relationship between IS/OS junction disruption and ERM grade. Methods: Fifty-four eyes of 54 patients with different grades of ERM were retrospectively reviewed. Patients were classified into three groups by ERM grade according to retinal striae and vessel distortion: grade/group 1, visible membranes without retinal striae or vessel distortion; grade/group 2, mild to moderate macular striae or vessel straightening; and grade/group 3, moderate to severe striae and vascular straightening...
September 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/27980358/epiretinal-proliferation-associated-with-macular-hole-and-intraoperative-perifoveal-crown-phenomenon
#18
Gisung Son, Ji Shin Lee, Suchan Lee, Joonhong Sohn
PURPOSE: To discuss the unique morphology and origin of epiretinal proliferation associated with macular hole (EPMH) occasionally observed in full-thickness macular hole (FT-MH) or lamellar hole (LH) and to introduce the perifoveal crown phenomenon encountered when removing this unusual proliferative tissue. METHODS: Sixteen patients showing EPMH in spectral domain-optical coherence tomography were selected from 212 patients diagnosed with MH, LH, FT-MH, impending MH, macular pseudohole, or epiretinal membrane between January 2013 and December 2014...
December 2016: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/27977831/spectral-domain-optical-coherence-tomography-in-older-patients-with-history-of-retinopathy-of-prematurity
#19
Aristomenis Thanos, Yoshihiro Yonekawa, Bozho Todorich, Natalie Huang, Kimberly A Drenser, George A Williams, Michael T Trese, Antonio Capone
BACKGROUND AND OBJECTIVE: To characterize the in vivo microstructural features of patients with history of retinopathy of prematurity (ROP). PATIENTS AND METHODS: A single-center, retrospective imaging case series during which a chart review was performed of consecutive patients with history of ROP who underwent spectral-domain optical coherence tomography (SD-OCT) with or without enhanced depth imaging. Eyes with time-domain OCT, no light perception, or uninterpretable SD-OCT images were excluded...
December 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/27957600/vitreoretinal-interface-abnormalities-in-patients-treatedwith-ranibizumab-for-diabetic-macular-oedema
#20
Yun Wong, David H W Steel, Maged S Habib, Alex Stubbing-Moore, Dalvir Bajwa, Peter J Avery
PURPOSE: Intravitreal anti-vascular endothelial growth factor (VEGF) agents are effective in the treatment of central involving diabetic macular oedema (DMO). Vitreoretinal interface abnormalities (VRIA) are common in patients with DMO, and the effect of these on the response to anti-VEGF treatment is unclear. Furthermore the effect of anti-VEGF agents on the VRIA itself is uncertain. METHOD: Prospective study of consecutive patients treated with ranibizumab (RZB) for DMO as part of routine clinical care in one eye unit over a 1-year period...
December 12, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
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