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https://www.readbyqxmd.com/read/28928983/influences-of-27-gauge-vitrectomy-on-corneal-topographic-conditions
#1
Takafumi Hirashima, Takao Utsumi, Miou Hirose, Hideyasu Oh
PURPOSE: To evaluate the influences of 27-gauge vitrectomy on corneal topographic conditions. METHOD: Fifty-six eyes of 56 patients undergoing 27-gauge vitrectomy were retrospectively studied. Twenty-three eyes with epiretinal membrane (ERM), 23 eyes with macular hole (MH), and 10 eyes with proliferative diabetic retinopathy (PDR) were included. Forty-five of the 56 eyes underwent 27-gauge phacovitrectomy (group 1), and the remaining 11 eyes underwent 27-gauge vitrectomy alone (group 2)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28926197/epiretinal-membrane-surgery-an-analysis-of-2-step-sequential-or-combined-phacovitrectomy-surgery-on-refraction-and-macular-anatomy-in-a-prospective-trial
#2
Hassan Hamoudi, Ulrik Correll Christensen, Morten La Cour
PURPOSE: To assess the impact of combined phacoemulsification-vitrectomy and sequential surgery for idiopathic epiretinal membrane (ERM) on refractive error (RE) and macular morphology. METHODS: In this prospective clinical trial, we allocated phakic eyes with ERM to (1) cataract surgery and subsequent pars plana vitrectomy (PPV) (CAT group), (2) PPV and subsequent cataract surgery (VIT group) or (3) phaco-vitrectomy (COMBI group). Examinations were at baseline, one month after each surgery, and at 3 months and 12 months of follow-up...
September 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28922693/spontaneous-separation-of-epiretinal-membrane-a-report-of-three-cases
#3
Yun Chong Lim, Denise Tm Au Eong, Ajeet M Wagle, Kah Guan Au Eong
No abstract text is available yet for this article.
September 18, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28917408/refractive-outcome-comparison-between-vitreomacular-interface-disorders-after-phacovitrectomy
#4
Zeynep Eylül Ercan, İmren Akkoyun, Eylem Yaman Pınarcı, Gürsel Yılmaz, Hülya Topçu
PURPOSE: To compare the refractive accuracy of intraocular lens (IOL) power calculations between patients with vitreomacular interface disorders who had phacovitrectomy for vitreomacular traction (VMT), epiretinal membranes (ERM), and macular holes. SETTING: Baskent University Department of Ophthalmology, Ankara, Turkey. DESIGN: Retrospective case series. METHODS: Refraction results 8 weeks postoperatively were compared between phacovitrectomy (3 study groups comprising eyes with VMT with intrafoveal pseudocysts, ERM, or medium-to-large macular holes) and phacoemulsification (control group comprising eyes having phacoemulsification only)...
August 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28914687/prevention-of-macular-edema-after-cataract-surgery
#5
Laura H P Wielders, Jan S A G Schouten, Rudy M M A Nuijts
PURPOSE OF REVIEW: Although cataract surgery can effectively restore visual function in many patients with cataract, pseudophakic cystoid macular edema (PCME) remains an important cause of suboptimal visual acuity. The present review provides an overview of the current literature on the prevention and treatment of PCME. RECENT FINDINGS: Optimal prevention of PCME starts preoperatively with a personalized risk assessment. Diabetes mellitus, retinal vein occlusion, epiretinal membrane, macular hole, and uveitis are the most important risk factors for developing cystoid macular edema after cataract surgery...
September 12, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28914577/unbalanced-vitreous-levels-of-osteoprotegerin-rankl-rank-and-trail-in-proliferative-diabetic-retinopathy
#6
Ahmed M Abu El-Asrar, Ajmal Ahmad, Kaiser Alam, Emilie Bittoun, Mohammad Mairaj Siddiquei, Ghulam Mohammad, Ahmed Mousa, Gert De Hertogh, Ghislain Opdenakker
PURPOSE: We investigated the expression of the proinflammatory and proangiogenic factor osteoprotegerin (OPG) and its ligands, receptor activator of nuclear factor-κB ligand (RANKL), tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), and the receptor RANK in proliferative diabetic retinopathy (PDR). MATERIALS AND METHODS: Vitreous samples from PDR and nondiabetic control patients and epiretinal membranes from PDR patients were studied by enzyme-linked immunosorbent assay, immunohistochemistry, and Western blot analysis...
September 15, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28914000/trends-of-pars-plana-vitrectomy-rates-in-south-korea-a-nationwide-cohort-study
#7
Joo Yeon Kim, Tyler Hyungtaek Rim, Sung Soo Kim
PURPOSE: To assess the trends in pars plana vitrectomy surgery rates and factors affecting rate change between 2002 and 2013 in South Korea. METHODS: Data from National Health Insurance Service-National Sample Cohort 2002-2013, which represents 1,025,340 samples with a sampling rate of 2.2% from the total eligible Korean population, was analyzed. RESULTS: A total of 3,816 vitrectomy procedures were performed (male, 2,010; female, 1,806) from 2002 to 2013...
August 18, 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28913997/additive-effect-of-oral-steroid-with-topical-nonsteroidal-anti-inflammatory-drug-for-preventing-cystoid-macular-edema-after-cataract-surgery-in-patients-with-epiretinal-membrane
#8
Seonghwan Kim, Mee Kum Kim, Won Ryang Wee
PURPOSE: To investigate the additive effect of oral steroid with topical nonsteroidal anti-inflammatory drug (NSAID) on cystoid macular edema (CME) in patients with epiretinal membrane (ERM) after cataract surgery. METHODS: Medical records of subjects who underwent uneventful cataract surgery (n = 1,349) were retrospectively reviewed; among these patients, those with pre-existing ERM (n = 81) were included. Patients were divided into two groups: one group had postoperative administration of oral steroid for 1 week (n = 45) and the other group did not have oral steroid administration (n = 36)...
August 18, 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28910435/repeatability-and-reproducibility-of-superficial-macular-retinal-vessel-density-measurements-using-optical-coherence-tomography-angiography-en-face-images
#9
Jianqin Lei, Mary K Durbin, Yue Shi, Akihito Uji, Siva Balasubramanian, Elmira Baghdasaryan, Mayss Al-Sheikh, Srinivas R Sadda
Importance: The repeatability and reproducibility of quantitative metrics from optical coherence tomographic angiography (OCTA) must be assessed before these data can be confidently interpreted in clinical research and practice. Objective: To evaluate the repeatability and reproducibility of OCTA-derived retinal vascular quantitative metrics. Design, Setting and Participants: In this cross-sectional study, 21 healthy volunteers (42 eyes) and 22 patients with retinal disease (22 eyes), including 14 with age-related macular degeneration, 3 with epiretinal membrane, 2 with diabetic retinopathy, 2 with myopic macular degeneration, and 1 with retinal vein occlusion, were enrolled...
September 14, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28904217/two-orthoptic-treatments-in-dragged-fovea-diplopia-syndrome
#10
Silvia Maddii, Ilaria Biagini, Alessia Aragno, Mario Scrivanti, Barbara Giambene, Stanislao Rizzo, Gianni Virgili
BACKGROUND: "Dragged-fovea diplopia syndrome" is a type of central binocular diplopia that is secondary to a foveal displacement, caused by epiretinal membranes (ERMs) or other macular diseases. Its management is difficult, because prisms are not effective. CASE REPORTS: Two cases of dragged-fovea diplopia syndrome were presented. Both patients were affected with a unilateral epiretinal membrane. Therefore, the pathophysiology underlying their diplopia was the conflict between central and peripheral fusion mechanisms...
January 2017: American Orthoptic Journal
https://www.readbyqxmd.com/read/28892948/microperimetry-a-new-tool-for-assessing-retinal-sensitivity-in-macular-diseases
#11
Memota Laishram, Krishnagopal Srikanth, A R Rajalakshmi, Swathi Nagarajan, G Ezhumalai
INTRODUCTION: Macular disease is the leading cause of low vision in the Western world. Drusen and pigmentary irregularities are common among the rural Northern Indian population. The disease process leads to loss of central vision, metamorphopsia, macropsia or micropsia and colour vision defect. AIM: To study the retinal sensitivity changes in macular diseases using microperimetry. MATERIALS AND METHODS: It was an observational study, conducted in the Department of Ophthalmology at a rural tertiary care hospital...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28882646/protective-effect-of-mir-200b-c-by-inhibiting-vasohibin-2-in-human-retinal-microvascular-endothelial-cells
#12
Yuzhi Ding, Zizhong Hu, Jie Luan, Xuehua Lv, Dongqing Yuan, Ping Xie, Songtao Yuan, Qinghuai Liu
AIMS: Proliferative diabetic retinopathy (PDR), characterized by angiogenesis, can cause serve vision loss and even blindness. Recent studies have suggested a pivotal role of vasohibin-2 (VASH2) in the promotion of angiogenesis in tumor tissues. Here we further investigated the role of VASH2 in the proliferation and migration of retinal endothelial cells. MAIN METHODS: The expression of VASH2 in vascular endothelial cells of epiretinal fibrovascular membranes (FVMs) from PDR patients were detected by immunofluorescence...
September 4, 2017: Life Sciences
https://www.readbyqxmd.com/read/28878218/lack-of-evidence-for-vasoactive-and-inflammatory-mediators-in-the-promotion-of-macular-edema-associated-with-epiretinal-membranes
#13
Brooks P Applewhite, Savalan Babapoor-Farrokhran, David Poon, Syed Junaid Hassan, Elizabeth Wellmann, Howard S Ying, Gregg L Semenza, Silvia Montaner, Akrit Sodhi
The development of symptoms in patients with epiretinal membranes (ERMs) often corresponds with the accumulation of interstitial fluid in the retina [i.e., the development of macular edema, (ME)]. To explore the potential value of pharmacologic therapeutic options to treat ME in patients with ERMs, we examine here the expression of vasoactive and inflammatory mediators in the vitreous of patients with idiopathic ERMs. We observed that vitreous concentrations of classic vasoactive factors (e.g., vascular endothelial growth factor) were similar in ERM patients with ME compared to controls...
September 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28877445/anti-fibrosis-effect-of-nanoparticle-mediated-delivery-of-plasminogen-kringle-5
#14
Yi Lu, Weizhong Gu, Yanhong Ren, Jia Feng, Lili Yang, Ji Jin
Retinal fibrosis, including epiretinal membrane (ERM) and proliferative vitreoretinopathy (PVR), is an ocular disease that can lead to blindness. An efficacious therapy remains an unmet medical challenge. In this study, we intended to explore the inhibitory effects of the nanoparticle-mediated delivery of plasminogen kringle 5 (K5-NPs) on laser-induced ERM and to identify the potential anti-fibrosis targets of K5-NPs. A rat model of laser-induced ERM was used. Control-NPs or K5-NPs were intravitreally injected...
June 2017: Discovery Medicine
https://www.readbyqxmd.com/read/28860703/refractive-changes-after-lens-sparing-vitrectomy-for-macular-hole-and-epiretinal-membrane
#15
Tetsuya Muto, Tomoharu Nishimura, Takefumi Yamaguchi, Makoto Chikuda, Shigeki Machida
PURPOSE: Cataract progression after lens-sparing vitrectomy might differ according to original posterior segment diseases. Our objective was to analyze the refractive values after lens-sparing vitrectomy for macular hole (MH) and epiretinal membrane (ERM). MATERIALS AND METHODS: We reviewed the medical records of 25 MH patients (25 eyes) and 23 ERM patients (23 eyes) who underwent lens-sparing vitrectomy. Refractive changes in both groups were compared. All patients underwent 20-gauge three-port pars plana vitrectomy...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28858193/utility-of-intraoperative-optical-coherence-tomography-in-acute-endophthalmitis
#16
Shigeharu Yaginuma, Makoto Inoue, Yuji Itoh, Hiroyuki Takahashi, Akito Hirakata
PURPOSE: To evaluate the efficacy of intraoperative optical coherence tomography (OCT) during vitrectomy for acute endophthalmitis. METHODS: The intraoperative and postoperative images of an 87-year-old woman with acute endophthalmitis after uncomplicated cataract surgery were analyzed. RESULTS: At presentation, the vision of the patient was 20/2000, and the preoperative OCT was unable to obtain clear images because of vitreous opacities. Intraoperative OCT showed that the inner retinal layer was hyperreflective because of diffuse retinal edema...
August 28, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28858064/postoperative-changes-and-prognostic-factors-of-visual-acuity-metamorphopsia-and-aniseikonia-after-vitrectomy-for-epiretinal-membrane
#17
Moe Takabatake, Tomomi Higashide, Sachiko Udagawa, Kazuhisa Sugiyama
PURPOSE: To investigate postoperative changes and prognostic factors of visual impairment after vitrectomy for unilateral epiretinal membrane. METHODS: A prospective observational study on 45 eyes from 45 patients with unilateral idiopathic epiretinal membrane who underwent vitrectomy. Visual parameters (best-corrected visual acuity, metamorphopsia using M-CHARTS, and aniseikonia using the New Aniseikonia Test) and spectral domain optical coherence tomography parameters (macular retinal layer thickness and microstructure of the outer retina) were measured preoperatively and 6 and 12 months postoperatively...
August 28, 2017: Retina
https://www.readbyqxmd.com/read/28845304/double-internal-limiting-membrane-insertion-for-macular-hole-associated-retinal-detachment
#18
San-Ni Chen, Chung-May Yang
PURPOSE: To describe a modified technique of internal limiting membrane (ILM) insertion for macular hole- (MH-) associated retinal detachment (RD) in highly myopic eyes. METHODS: Nine eyes underwent pars plana vitrectomy, cortical vitreous removal, and fovea-sparing ILM peeling. Double ILM insertion into the hole was performed with inverted perifoveal ILM and a free ILM flap followed by air-fluid exchange. RESULTS: Two of the 9 eyes had perifoveal ILM partially torn after cortical vitreous or epiretinal removal...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28834949/benefit-of-intraoperative-optical-coherence-tomography-for-vitreomacular-surgery-in-highly-myopic-eyes
#19
Elsa Bruyère, Elise Philippakis, Bénédicte Dupas, Pauline Nguyen-Kim, Ramin Tadayoni, Aude Couturier
PURPOSE: To report the feasibility and information provided by intraoperative optical coherence tomography (iOCT) during vitreomacular surgery in highly myopic eyes. METHODS: Retrospective observational case series on consecutive highly myopic eyes that underwent vitreomacular surgery with iOCT for epiretinal membrane (ERM), macular hole, and myopic foveoschisis. The main outcome was the qualitative and quantitative assessment of retinal changes: detection of persistent epiretinal structures, new openings, central macular thickness, and macular hole diameters after each step of the surgical procedure...
August 22, 2017: Retina
https://www.readbyqxmd.com/read/28834919/a-case-of-neurofibromatosis-type-2-with-unusual-clinical-features
#20
Mohamma Zarei, Parisa Hamzeloui, Ramak Rooipoor, Masoud Aghsaei Fard
PURPOSE: To report a case of a neurofibromatosis Type 2 with unusual clinical features. METHODS: Observational clinical case report. RESULTS: A 22-year-old woman was referred with bilateral blurred vision and macular "scars." Ocular examination revealed bilateral posterior subcapsular and cortical cataract, optic disk swelling, hyperpigmented macular lesions, epiretinal membrane, and macular temporal dragging. Spectral-domain optical coherence tomographic imaging showed bilateral epiretinal membranes, peripapillary nerve fiber layer thickening, and vitreoretinal tractional bands...
August 21, 2017: Retinal Cases & Brief Reports
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