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epiretinal membrane

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https://www.readbyqxmd.com/read/28632410/correlation-between-interleukin-6-and-thrombin-antithrombin-iii-complex-levels-in-retinal-diseases
#1
Rita Ehrlich, Alon Zahavi, Ruth Axer-Siegel, Ivan Budnik, Ayelet Dreznik, Mor Dahbash, Yael Nisgav, Elinor Megiddo, Gili Kenet, Dov Weinberger, Tami Livnat
PURPOSE: This study aims to evaluate and correlate the levels of interleukin-6 (IL-6) and thrombin-antithrombin III complex (TAT) in the vitreous of patients with different vitreoretinal pathologies. METHODS: Vitreous samples were collected from 78 patients scheduled for pars plana vitrectomy at a tertiary medical center. Patients were divided by the underlying vitreoretinal pathophysiology, as follows: macular hole (MH)/epiretinal membrane (ERM) (n = 26); rhegmatogenous retinal detachment (RRD) (n = 32); and proliferative diabetic retinopathy (PDR) (n = 20)...
June 20, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28631180/microvascular-changes-after-vitrectomy-with-internal-limiting-membrane-peeling-an-optical-coherence-tomography-angiography-study
#2
Leonardo Mastropasqua, Enrico Borrelli, Paolo Carpineto, Lisa Toto, Luca Di Antonio, Peter A Mattei, Rodolfo Mastropasqua
PURPOSE: To evaluate superficial capillary plexus (SCP) changes occurring after internal limiting membrane (ILM) peeling for the treatment of idiopathic epiretinal membrane (ERM). METHODS: A total of 15 eyes of 15 patients affected by idiopathic ERM (eight males and seven females; mean age 59.8 ± 9.6 years) were enrolled in the study. Patients were treated with pars plana vitrectomy followed by ERM and ILM peeling. Subjects were evaluated at baseline and at the week-1 and month-1 follow-up visits...
June 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28629400/characteristics-of-syphilitic-uveitis-in-northern-china
#3
Xiaomin Zhang, Qian Du, Feifei Ma, Yinglong Lu, Meiyan Wang, Xiaorong Li
BACKGROUND: To describe the characteristics of patients with syphilitic uveitis in northern China. METHODS: A case series of 21 patients (33 eyes) diagnosed with syphilitic uveitis from 2011 to 2016 at a tertiary center in northern China was retrospectively analyzed. RESULTS: Twenty-one patients (33 eyes) were diagnosed as syphilitic uveitis. Posterior segment involvement was found in 32 eyes (97.0%). Vitreous haze, neuroretinitis, and posterior placoid chorioretinitis were mainly found in patients with a relatively short duration of the disease, while diffuse chorioretinitis, pseudoretinitis pigmentosa, cystoid macular edema, and epiretinal membrane were found in patients with relatively long duration of ocular involvement...
June 19, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28624313/eplerenone-a-new-treatment-for-an-old-problem-retinitis-pigmentosa-with-recalcitrant-macular-edema
#4
R Campos Polo, C Rubio Sánchez, D M García Guisado, M J Díaz Luque
CASE REPORT: The case involves a 35-year-old man, with a history of retinitis pigmentosa, who presented with a bilateral cystoid macular oedema associated with bilateral epiretinal membrane, which was resistant to treatment with oral acetazolamide and intravitreal bevacizumab. The treatment with oral eplerenone was able to improve the visual acuity and macular thickness of this patient. DISCUSSION: A variety of treatments have been proposed for the management of cystoid macular oedema, associated with retinitis pigmentosa, with variable results...
June 14, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28622372/vitrectomy-with-or-without-internal-limiting-membrane-peeling-for-idiopathic-epiretinal-membrane-a-meta-analysis
#5
Wei-Cheng Chang, Chin Lin, Cho-Hao Lee, Tzu-Ling Sung, Tao-Hsin Tung, Jorn-Hon Liu
BACKGROUND: Studies on vitrectomy with and without internal limiting membrane (ILM) peeling for idiopathic epiretinal membrane (ERM) have yielded uncertain results regarding clinical outcomes and recurrence rates. OBJECTIVE: To compare the clinical outcomes of vitrectomy with and without ILM peeling for idiopathic ERM. METHODS: Databases, including PubMed, Embase, Cochrane, Web of Science, Google Scholar, CNKI databases, FDA.gov, and ClinicalTrials...
2017: PloS One
https://www.readbyqxmd.com/read/28608032/the-significance-of-neutrophil-to-lymphocyte-ratio-in-idiopathic-epiretinal-membrane
#6
Funda Dikkaya, Sevil Karaman Erdur, Mustafa Ozsutcu, Rukiye Aydin, Mehmet Selim Kocabora, Cengiz Aras
PURPOSE: To assess the levels of neutrophil-to-lymphocyte ratio (NLR) in patients with idiopathic epiretinal membrane (iERM) and to compare the NLR results of patients with iERM and healthy controls. METHODS: This retrospective study enrolled 43 patients with iERM and 40 healthy subjects. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within 2 h of blood collection. RESULTS: There was a significant difference in NLR between iERM and control groups (p < 0...
June 12, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28604979/femtosecond-laser-assisted-cataract-in-vitreoretinal-surgery
#7
Stanislao Rizzo, Daniela Bacherini, Francesco Faraldi, Marco Pellegrini, Cesare Mariotti
PURPOSE: To assess the safety and surgical results of femtosecond laser-assisted phacovitrectomy. METHODS: Fifteen patients over 50 years of age with coexisting vitreoretinal pathologies and cataract underwent combined femtosecond laser-assisted cataract extraction and sutureless 25-G and 27-G vitreoretinal surgery. RESULTS: The indication for surgery was macular hole in 6 patients, epiretinal membrane in 6, vitreous hemorrhage in 2, and retinal detachment in 1...
June 2, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28602014/correlation-between-morphological-changes-and-functional-outcomes-of-recent-onset-macula-off-rhegmatogenous-retinal-detachment-prognostic-factors-in-rhegmatogenous-retinal-detachment
#8
Murat Karacorlu, Isil Sayman Muslubas, Mumin Hocaoglu, Serra Arf, Mehmet Giray Ersoz
PURPOSE: To assess correlation between preoperative and postoperative findings and surgical factors, and postoperative functional outcomes after successful repair of acute macula-off rhegmatogenous retinal detachment (RRD). METHODS: Forty-four eyes of 44 patients with recent-onset macula-off RRD who had primary pars plana vitrectomy were included in this retrospective study. Best-corrected visual acuity (BCVA) and retinal and choroidal changes on spectral-domain optical coherence tomography (SD-OCT) were evaluated before and after surgery...
June 10, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28601586/evaluating-structural-progression-of-retinitis-pigmentosa-after-cataract-surgery
#9
Joaquin O De Rojas, Kaspar Schuerch, Priya M Mathews, Thiago Cabral, Albert Hazan, Janet Sparrow, Stephen H Tsang, Leejee H Suh
PURPOSE: To determine whether cataract surgery accelerates disease progression in retinitis pigmentosa (RP). DESIGN: Retrospective cohort study. METHODS: Seventy eyes of 40 patients with RP were categorized as having had phacoemulsification with intraocular lens implantation versus no cataract surgery at a single tertiary-level institution. Spectral domain optical coherence tomography (SD-OCT) was used to measure the ellipsoid zone (EZ) width, which has been demonstrated to be a reliable marker of RP severity, at baseline and throughout follow-up (median 768 days)...
June 7, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28594752/residual-vitreous-cortex-at-the-fovea-during-vitrectomy-for-primary-rhegmatogenous-retinal-detachment-repair
#10
Eun Hyung Cho, Hee Chan Ku, Won Il, Eun Koo Lee
PURPOSE: To investigate the frequency of residual cortex and the effectiveness of removal of residual cortex in the fovea during vitrectomy for primary rhegmatogenous retinal detachment repair. METHODS: We retrospectively reviewed the charts and the operative videos of the 80 patients (80 eyes) who underwent vitrectomy for repair and who were observed for more than 6 months. After triamcinolone acetonide injection, we observed residual cortex on the surface of the retina...
June 7, 2017: Retina
https://www.readbyqxmd.com/read/28590966/characteristics-of-epiretinal-membrane-remnant-edge-by-optical-coherence-tomography-after-pars-plana-vitrectomy
#11
Raouf Gaber, Qi Sheng You, Ilkay Kilic Muftuoglu, Mostafa Alam, Frank F Tsai, Nadia Mendoza, William R Freeman
PURPOSE: To evaluate the incidence, characteristics, and the progression of epiretinal membrane (ERM) remnant edge seen by optical coherence tomography after ERM peeling. METHODS: A retrospective chart review was conducted for 86 eyes of 85 consecutive patients who were diagnosed with ERM and underwent pars plana vitrectomy for epiretinal membrane peeling between 2013 and 2014. Data collected and analyzed included age, gender, preoperative and postoperative visual acuity, use of indocyanine green dye to stain internal limiting membrane, tamponade used after vitrectomy, ERM edge boundaries, presence of cystoid macular edema, and central foveal thickness...
January 11, 2017: Retina
https://www.readbyqxmd.com/read/28590320/sticky-silicone-oil
#12
Hamouda Hamdi Ghoraba, Adel Galal Zaky, Haithem Mamoun Abd Al Fatah, Emad El Din Mohamed El Gemai, Mohamed Amin Heikal
OBJECTIVE: To report and analyze the phenomenon of sticky silicone oil on the retina at the time of its removal. BACKGROUND: Silicone oil has been used for more than 25 years as a long-term retinal tamponade in the surgical management of patients with complex retinal detachments. When a decision to remove silicone oil was made at the end of the tamponade period, the system involved a number of different materials: silicone oil, aqueous solution with or without remnants of perfluorocarbon liquid plus the material of the cannula used to aspirate Silicone oil...
October 31, 2016: Retina
https://www.readbyqxmd.com/read/28590319/surgical-outcomes-of-27-gauge-vitrectomy-for-a-consecutive-series-of-163-eyes-with-various-vitreous-diseases
#13
Kazuhito Yoneda, Keisuke Morikawa, Yusuke Oshima, Shigeru Kinoshita, Chie Sotozono
PURPOSE: To evaluate the safety and efficacy of 27-gauge vitrectomy for various vitreoretinal disorders. METHODS: In this retrospective comparative study, 163 consecutive eyes with various diseases that underwent 27-gauge pars plana vitrectomy with or without ultraspeed transformer by a single surgeon from June 2012 through December 2014 were analyzed in regard to best-corrected visual acuity, intraocular pressure, intraoperative and postoperative complications, and surgery time...
January 4, 2017: Retina
https://www.readbyqxmd.com/read/28579750/refractive-predictability-in-eyes-with-intraocular-gas-tamponade-results-of-a-prospective-controlled-clinical-trial
#14
Lars Wagenfeld, Kristin Hermsdorf, Birthe Stemplewitz, Vasyl Druchkiv, Andreas Frings
PURPOSE: To determine the postoperative refractive error in eyes with intraocular gas tamponade in combined phacovitrectomy using a Z-haptic intraocular lens (IOL). METHODS: This prospective non-randomized case-control study compared patients with combined phacovitrectomy with or without intraocular gas tamponade to cataract surgery-only. The main outcome measure was the IOL power prediction error (PE). Secondary outcome measures were spherical equivalent, anterior chamber depth (ACD), and axial length...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28576849/proteome-wide-identification-of-glycosylation-dependent-interactors-of-galectin-1-and-galectin-3-on-mesenchymal-retinal-pigment-epithelial-cells
#15
Jara Obermann, Claudia S Priglinger, Juliane Merl-Pham, Arie Geerlof, Sigfried Priglinger, Magdalena Götz, Stefanie M Hauck
Identification of interactors is a major goal in cell biology. Not only protein-protein but also protein-carbohydrate interactions are of high relevance for signal transduction in biological systems. Here we aim to identify novel interacting binding partners for the β-galactoside-binding proteins Galectin-1 (Gal-1) and Galectin-3 (Gal-3) relevant in the context of the eye disease proliferative vitreoretinopathy (PVR). PVR is one of the most common failures after retinal detachment surgeries and is characterized by the migration, adhesion and epithelial-to-mesenchymal transition (EMT) of retinal pigment epithelial cells (RPE) and the subsequent formation of sub- and epiretinal fibrocellular membranes...
June 2, 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/28576207/effect-of-air-and-sulfur-hexafluoride-sf6-tamponade-on-visual-acuity-after-epiretinal-membrane-surgery-a-pilot-study
#16
Guillaume Chabot, Serge Bourgault, Benoit Cinq-Mars, Éric Tourville, Mathieu Caissie
OBJECTIVE: The aim of this study was to compare visual acuity improvement after epiretinal membrane (ERM) surgery using air and sulfur hexafluoride (SF6) tamponade. Secondary objectives were to evaluate Visual Function Questionnaire (VFQ) scores and central retinal thickness (CRT) changes. DESIGN: This was a prospective, randomized study. PARTICIPANTS: Thirty-two patients were prospectively randomized, 19 to the air group and 13 to the SF6 group...
June 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28546935/prognostic-factors-of-short-term-outcomes-of-intravitreal-ranibizumab-in-diabetic-macular-edema
#17
I-An Lai, Wei-Cherng Hsu, Chung-May Yang, Yi-Ting Hsieh
AIM: To evaluate the prognostic factors for short-term visual and anatomical improvement of intravitreal ranibizumab (IVR) for diabetic macular edema (DME). METHODS: Fifty-one eyes from 35 patients that received three consecutive monthly IVR for DME with moderate visual loss were retrospectively recruited; all cases had their baseline best-corrected visual acuity (BCVA) between 20/400 and 20/40. BCVA and central subfield thickness (CST) at baseline and month 3 were collected...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28546149/progression-of-lamellar-hole-associated-epiretinal-proliferation-and-retinal-changes-during-long-term-follow-up
#18
Denise Compera, Ricarda G Schumann, Matteo G Cereda, Alessandra Acquistapace, Viviane Lita, Siegfried G Priglinger, Giovanni Staurenghi, Ferdinando Bottoni
PURPOSE: To report on progression of lamellar hole-associated epiretinal proliferation (LHEP) in eyes with lamellar macular holes (LMH) using spectral-domain optical coherence tomography (SD-OCT), and to correlate with intraretinal changes and visual function. METHODS: From a retrospectively reviewed series of 167 eyes with non-full-thickness macular holes, we exclusively included a subgroup of 34 eyes with LMH and LHEP by SD-OCT evaluation. In these eyes, area of LHEP, intraretinal changes of defect diameter, central retinal thickness, defects of the ellipsoid zone and occurrence of a contractive epiretinal membrane were analysed...
May 25, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28542230/visual-field-changes-after-vitrectomy-with-internal-limiting-membrane-peeling-for-epiretinal-membrane-or-macular-hole-in-glaucomatous-eyes
#19
Shunsuke Tsuchiya, Tomomi Higashide, Kazuhisa Sugiyama
PURPOSE: To investigate visual field changes after vitrectomy for macular diseases in glaucomatous eyes. METHODS: A retrospective review of 54 eyes from 54 patients with glaucoma, who underwent vitrectomy for epiretinal membrane (ERM; 42 eyes) or macular hole (MH; 12 eyes). Standard automated perimetry (Humphrey visual field 24-2 program) was performed and analyzed preoperatively and twice postoperatively (1st and 2nd sessions; 4.7 ± 2.5, 10.3 ± 3.7 months after surgery, respectively)...
2017: PloS One
https://www.readbyqxmd.com/read/28525683/multilayer-microstructure-of-idiopathic-epiretinal-macular-membranes
#20
Claudio Azzolini, Terenzio Congiu, Simone Donati, Alberto Passi, Petra Basso, Eliana Piantanida, Cesare Mariotti, Francesco Testa, Simona M Caprani, Jennifer Cattaneo, Riccardo Vinciguerra
PURPOSE: To identify the ultramicroscopic structure of idiopathic epiretinal macular membranes (iEMMs) by scanning electron microscopy (SEM). METHODS: We examined 28 iEMMs surgically removed from 28 eyes of 28 patients. All specimens, previously observed at stereomicroscope, were treated with an osmium maceration technique. Fine resolution of iEMMs' 3D architecture and their interaction with the retina were studied using a Philips SEM-FEG XL-30 microscope. RESULTS: The specimens appeared as laminar connective structures partially or completely adherent to the inner limiting membrane (ILM)...
May 19, 2017: European Journal of Ophthalmology
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