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https://www.readbyqxmd.com/read/29327033/disorganization-of-inner-retina-and-outer-retinal-morphology-in-diabetic-macular-edema
#1
Radha Das, Gareth Spence, Ruth E Hogg, Michael Stevenson, Usha Chakravarthy
Importance: In diabetic macular edema (DME), identification of baseline markers on spectral-domain optical coherence tomography (SD-OCT) and their association with severity of diabetic retinopathy (DR) might aid in disease management and the design of future trials. Objective: To examine associations between DR severity, retinal morphology on SD-OCT, and visual acuity in participants with DME. Design, Setting, and Participants: This cross-sectional observational case series was conducted at a single tertiary care referral center...
January 11, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29325389/-development-of-en-face-optical-coherence-tomography-and-its-application-in-ocular-fundus-diseases
#2
Y Zhou, M Wang
Optical coherence tomography (OCT) is able to obtain the cross-sectional image of the fundus noninvasively and quickly. The cross-sectional image in vivo almost matches the histological section of the retina. OCT has become the most important imaging tool in ophthalmology. Based on the latest OCT technology, en face OCT is a new imaging technique that reveals the structure of retinal and choroidal sections approximately paralleled to the retina surface. Compared to the conventional OCT, en face OCT provides more comprehensive information and makes more accurate diagnosis and assessment of the prognosis...
December 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29324594/intraoperative-and-postoperative-complications-in-phacovitrectomy-for-epiretinal-membrane-and-macular-hole-a-clinical-audit-of-1000-consecutive-eyes
#3
Mark A P Fajgenbaum, James E Neffendorf, Roger S Wong, David A H Laidlaw, Tom H Williamson
PURPOSE: The aim of this study was to report the intraoperative and postoperative complications of phacovitrectomy for epiretinal membrane (ERM) and macular hole (MH). METHODS: This was a retrospective audit of 1,052 phacovitrectomy operations (410 for ERM and 642 for MH) by the same surgical team between 1998 and 2017. Outcome measures included rates of intraoperative anterior segment and posterior segment complications such as posterior capsule rupture and retinal breaks...
January 10, 2018: Retina
https://www.readbyqxmd.com/read/29315126/recurrent-opening-and-closure-of-macular-hole-after-pars-plana-vitrectomy-for-rhegmatogenous-retinal-detachment
#4
Ece Ozdemir, Sengul Ozdek
PURPOSE: To report a case of full-thickness macular hole formation and closure twice after pars plana vitrectomy for macula-off rhegmatogenous retinal detachment. METHODS: Case report. RESULTS: A 45-year-old woman with a macula-off rhegmatogenous retinal detachment underwent uncomplicated pars plana vitrectomy with silicone oil tamponade, which was removed 3 months postoperatively. A full-thickness macular hole developed spontaneously 18 months after silicone oil removal, concurrently with the formation of epiretinal membrane and perifoveal cystoid changes...
January 5, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29299741/functional-and-structural-outcomes-of-ilm-peeling-in-uncomplicated-macula-off-rrd-using-microperimetry-en-face-oct
#5
Mohamed Gaber Ahmed Mohamed Eissa, Mohamad Amr Salah Eddin Abdelhakim, Tamer Ahmed Macky, Mohamed Mahmoud Khafagy, Hassan Aly Mortada
PURPOSE: To investigate functional and structural outcomes of internal limiting membrane (ILM) peeling during primary vitrectomy for uncomplicated macula-off rhegmatogenous retinal detachment (RRD). METHODS: In this prospective interventional randomized comparative study, 43 eyes (43 patients) were randomly divided into group A (20), and group B (23), with and without ILM peeling respectively. Patients were evaluated clinically, and by spectral-domain optical coherence tomography (SD-OCT) and microperimetry (MP) following silicone oil removal...
January 3, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29298439/tips-tricks-and-advantages-of-27-g-vitrectomy
#6
Konstantinos Anastasilakis, Anna Mourgela, Dhmos Kaniouras, Konstantinos Moschou
PURPOSE: We present the advantages and technique variations of 27-G vitrectomy in a variety of surgical retina cases. METHODS: Patients with epiretinal membrane, retinal detachment, and proliferative diabetic retinopathy with vitreous hemorrhage and tractional detachments underwent 27-G vitrectomy. We present technique tricks, solutions to various problems and pitfalls, and the advantages of 27-G vitrectomy. RESULTS: Postoperative visual acuity improved significantly in all patients...
January 3, 2018: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/29290462/-retinal-hemangioblastoma-treatment-strategy-and-long-term-follow-up-in-a-retrospective-cohort
#7
A Lefevre, T Mathis, P Denis, L Kodjikian
INTRODUCTION: Retinal hemangioblastoma (RH) is a benign vascular tumor frequently associated with Von Hippel-Lindau disease (VHL). Tumor growth of RH may lead to deterioration of visual acuity, which can be difficult to treat. Early diagnosis may reduce complication rate and side effects of treatment. The present retrospective study evaluates the long-term follow-up and complications of RH treatment as a function of the therapeutic strategy used. MATERIALS AND METHODS: The study included patients with RH, followed at Croix Rousse university hospital, Lyon between 2010 and 2017...
December 28, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29288413/anatomical-and-functional-outcomes-following-vitrectomy-for-dense-vitreous-hemorrhage-related-to-terson-syndrome-in-children
#8
Isil Sayman Muslubas, Murat Karacorlu, Mumin Hocaoglu, Mehmet Giray Ersoz, Serra Arf
PURPOSE: Our purpose was to assess anatomical and functional outcomes of vitrectomy in pediatric cases of Terson syndrome. METHODS: A total of 11 eyes of seven children diagnosed with Terson syndrome secondary to traumatic brain injury and 17 eyes of 12 children diagnosed with Terson syndrome secondary to nontraumatic brain hemorrhage who had 20-gauge or 23-gauge pars plana or pars plicata vitrectomy were included in this retrospective study. The primary outcome was the change in visual acuity from the preoperative examination to postoperative final follow-up...
December 29, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29286956/five-year-incidence-and-risk-factors-for-idiopathic-epiretinal-membranes
#9
Jeong Hun Bae, Su Jeong Song, Mi Yeon Lee
PURPOSE: The aim of this was to determine the 5-year incidence of idiopathic epiretinal membrane (ERM) and its risk factors in Korean adults. METHODS: A total of 2,152 participants aged 50 years or older enrolled in a health screening program. All participants underwent baseline ophthalmic and systemic examinations in 2006, and were reexamined after 5 years. Epiretinal membranes were diagnosed using fundus photographs taken at baseline and at the 5-year follow-up...
December 28, 2017: Retina
https://www.readbyqxmd.com/read/29285122/pathophysiological-correlations-between-fundus-fluorescein-angiography-and-optical-coherence-tomography-results-in-patients-with-idiopathic-epiretinal-membranes
#10
Ju Liu, Yong Qian, Shunnan Yang, Li Yan, Yi Wang, Meng Gao, Limei Liu, Yuanyuan Xiao, Bin Mo, Wu Liu
The aim of the current study was to determine the association between fundus fluorescein angiography (FFA) image results, optical coherence tomography (OCT) imaging results and visual functions in patients with idiopathic epiretinal membranes (ERMs). A total of 80 eyes from 40 patients diagnosed with ERM were analyzed. Best-corrected visual acuity (BCVA) and metamorphopsia were measured using the Early Treatment Diabetic Retinopathy Study eye chart and M-charts, respectively. Macular thickness and volume were determined using OCT...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29285067/morphologic-characteristics-and-clinical-significance-of-the-macular-sparing-area-in-patients-with-retinitis-pigmentosa-as-revealed-by-multicolor-imaging
#11
Guodong Liu, Qing Du, Khusbu Keyal, Fang Wang
Retinitis pigmentosa (RP) is an inherited retinal disease caused by the degeneration of photoreceptors and retinal pigment epithelium cells within the eye. The present study aimed to evaluate the effectiveness of multicolor imaging as a novel technique for the depiction of morphological features in the macular area of patients with RP. Additionally, the correlation between the size of the macular-sparing area and the best corrected visual acuity (BCVA), central visual field function and subfoveal choroidal thickness (SFCT) was analyzed...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29282403/epiretinal-membrane-in-dome-shaped-macula-complicated-with-serous-retinal-detachment-transient-efficacy-of-surgery
#12
Guillaume Soudier, Alain Gaudric, Vincent Gualino, Mathieu Nardin, Claude Speeg-Schatz, David Gaucher
Dome-shaped macula (DSM) is an entity recently described as a convex anterior protrusion of the macular area within a posterior myopic staphyloma. Specific complications were associated with DSM, like serous retinal detachment (SRD). We describe a woman presenting with a decreased vision at 20/50. SD-OCT scans were performed, showing a macular bulge. SRD was present and an epiretinal membrane could also be observed. Fluorescein angiography and indocyanin green angiography did not show any leakage nor choroidal neovascularization...
September 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29275341/qualitative-and-quantitative-assessment-of-posterior-segment-optical-coherence-tomography-images-using-standard-photos-the-liwan-eye-study
#13
Sean K Wang, Xinxing Guo, Ou Xiao, Yanxian Chen, Ran Liu, Wenyong Huang, Mingguang He
BACKGROUND/AIMS: To develop a standardised grading scheme, using standard photos, for spectral-domain ocular coherence tomography (SD-OCT) images of the posterior eye and evaluate the interobserver agreement among trained ophthalmologists in identifying pathological changes. METHODS: Subjects were recruited from Liwan District, Guangzhou, with SD-OCT data collection from June 2013 to November 2013 as part of 10-year follow-up visits from the Liwan Eye Study. All subjects underwent SD-OCT imaging of the macula with scanning lines analysed by two ophthalmologists to assess for the presence of 12 different posterior segment lesions...
December 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29259907/the-impact-of-macular-surgery-in-different-grades-of-epiretinal-membrane
#14
Cosar Batman, Mehmet Citirik
AIM: To assess the impact of macular surgery on the functional and anatomic outcomes of the patients in different grades of epiretinal membrane (ERM). METHODS: Seventy-one eyes of 71 patients who underwent 23-gauge transconjunctival sutureless pars plana vitrectomy for primary isolated ERM were evaluated in this study. RESULTS: There were 38 females (53.5%) and 33 males (46.5%). The average age of the patients was 68.1y (range 42-89y). Mean follow up period was 14mo (range 6-26mo)...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29259392/association-of-hmgb1-with-oxidative-stress-markers-and-regulators-in-pdr
#15
Ahmed M Abu El-Asrar, Kaiser Alam, Marta Garcia-Ramirez, Ajmal Ahmad, Mohammad Mairaj Siddiquei, Ghulam Mohammad, Ahmed Mousa, Gert De Hertogh, Ghislain Opdenakker, Rafael Simó
Purpose: We investigated the link among the proinflammatory cytokine high-mobility group box 1 (HMGB1) and 8-hydroxy-2'-deoxyguanosine (8-OHdG) as a marker of oxidative DNA damage, the endothelial adhesion molecule and oxidase enzyme vascular adhesion protein-1 (VAP-1), and the inducible cytoprotective molecule heme oxygenase-1 (HO-1) in proliferative diabetic retinopathy (PDR). We correlated the levels of these molecules with clinical disease activity and studied the proinflammatory activities of HMGB1 on rat retinas and human retinal microvascular endothelial cells (HRMECs)...
2017: Molecular Vision
https://www.readbyqxmd.com/read/29246578/personalized-proteomics-in-proliferative-vitreoretinopathy-implicate-hematopoietic-cell-recruitment-and-mtor-as-a-therapeutic-target
#16
C Nathaniel Roybal, Gabriel Velez, Marcus Toral, Stephen H Tsang, Alexander G Bassuk, Vinit B Mahajan
PURPOSE: To profile vitreous cytokine expression of proliferative vitreoretinopathy (PVR) patients DESIGN: Case-control study. METHODS: Liquid biopsies were collected from two groups: control subjects (n=3) undergoing pars plana vitrectomy to remove an epiretinal membrane (ERM), and test subjects (n=7) with varying degrees of PVR. A high-throughput cytokine screen measured expression of 200 cytokines. Cytokine expression patterns were prospectively validated in separate cohorts of control patients and those with PVR-A, PVR-B, and PVR-C (n=10 for each group)...
December 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29238614/recurrence-rate-and-need-for-reoperation-after-surgery-with-or-without-internal-limiting-membrane-removal-for-the-treatment-of-the-epiretinal-membrane
#17
Fernando José De Novelli, Mauro Goldbaum, Mario Luiz Ribeiro Monteiro, Fabio Bom Aggio, Mario Junqueira Nóbrega, Walter Yukihiko Takahashi
Purpose: To compare the recurrence rate and need for reoperation after epiretinal membrane surgery with and without removal of the internal limiting membrane. Methods: In this retrospective study, 125 patients operated for epiretinal membrane removal were evaluated, with a minimum 6-month follow-up. Removal of the epiretinal membrane (ERM) was performed in 78 patients, while 47 had removal of the epiretinal membrane associated with internal limiting membrane peeling (ERM + ILM)...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29237498/vitreous-hemorrhage-and-rhegmatogenous-retinal-detachment-that-developed-after-botulinum-toxin-injection-to-the-extraocular-muscle-case-report
#18
Dong Hyun Lee, Jinu Han, Sueng-Han Han, Sung Chul Lee, Min Kim
BACKGROUND: The authors report a case of a rare complication that occurred after botulinum toxin injection to the extraocular muscle, which was easily overlooked and successfully corrected by surgery. CASE PRESENTATION: A 34-year-old female patient visited our clinic for diplopia and ocular motility disorder after removal of an epidermoid tumor of the brain. At her initial visit, her best-corrected visual acuity (BCVA) was 20/20 for both eyes. An alternate cover test showed 45 prism-diopter esotropia and 3 prism-diopter hypertropia in the right eye...
December 13, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29232330/foveal-avascular-zone-area-analysis-using-optical-coherence-tomography-angiography-before-and-after-idiopathic-epiretinal-membrane-surgery
#19
Yorihisa Kitagawa, Hiroyuki Shimada, Ari Shinojima, Hiroyuki Nakashizuka
PURPOSE: To determine the size of the foveal avascular zone (FAZ) by optical coherence tomography angiography before and after idiopathic epiretinal membrane surgery. METHODS: Thirteen consecutive patients (13 eyes) with unilateral epiretinal membrane were studied retrospectively. Optical coherence tomography angiography was used to measure the FAZ area within 3 mm × 3 mm scans of the superficial (superficial FAZ) and deep plexus layers (deep FAZ) before and 6 months after vitrectomy...
December 11, 2017: Retina
https://www.readbyqxmd.com/read/29215533/surgical-removal-of-epiretinal-membrane-with-and-without-removal-of-internal-limiting-membrane-comparative-study-of-visual-acuity-features-of-optical-coherence-tomography-and-recurrence-rate
#20
Fernando J De Novelli, Mauro Goldbaum, Mario L R Monteiro, Fabio Bom Aggio, Walter Y Takahashi
PURPOSE: To study and compare visual acuity, foveal thickness, outer limiting layer, ellipsoid zone, and recurrence rate in patients undergoing removal of the epiretinal membrane with and without the removal of the internal limiting membrane (ILM). METHODS: Sixty-three patients who had the epiretinal membrane removed by a single surgeon were randomly assigned into 2 groups: Group 1 without additional removal of the ILM and Group 2 with removal of the ILM. Patients were followed up and evaluated at the first month, third month, and sixth month, postoperatively...
December 5, 2017: Retina
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