Alexandra B Moussa-Tooks, Adam Beermann, Karlos Manzanarez Felix, Michael Coleman, Sylvain Bouix, Daphne Holt, Kathryn E Lewandowski, Dost Öngür, Alan Breier, Martha E Shenton, Stephan Heckers, Sebastian Walther, Roscoe O Brady, Heather Burrell Ward
BACKGROUND: Psychomotor disturbances are observed across psychiatric disorders and often present as psychomotor slowing, agitation, disorganized behavior, or catatonia. Psychomotor function includes both cognitive and motor components, but the neural circuits driving these subprocesses and how they relate to symptoms have remained elusive for centuries. METHODS: We analyzed data from the Human Connectome Project for Early Psychosis, a multi-site study of 125 people with early psychosis and 58 healthy participants with resting-state fMRI and clinical characterization...
March 5, 2024: Biological Psychiatry