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https://www.readbyqxmd.com/read/28231678/-application-of-disease-risk-score-in-pharmacoepidemiologic-studies
#1
H Y Zhao, S Y Zhan
Disease risk score (DRS) can be used to adjust the confounding effects on data with high dimensions and can reduce related bias through balancing the risk or probability, regarding the development of some specific diseases, between the two compared groups. The DRS approach thus can be applied to studies of pharmacoepidemiology when administrative medical database is used for data analysis. Although DRS functions are similarly to the propensity scores (PS) under many situations, even with some advantages over PS or conventional analytical methods in some special exposure settings, the usage of DRS is far limited than the PS method...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231668/-prevalence-of-metabolic-syndrome-in-chinese-adults-in-2010-2012
#2
Y N He, W H Zhao, L Y Zhao, D M Yu, J Zhang, X G Yang, G G Ding
Objective: To estimate the prevalence and distribution of metabolic syndrome (MS) in Chinese adults. Methods: Cross-sectional data on 104 098 men and women aged 18 years or above was gathered from 150 monitoring sites from 31 provinces, autonomous regions, and municipalities from the China National Health and Nutrition Surveillance (2010-2012) Project. Data was randomly selected by multi-stage stratified and Probability Proportionate to Size (PPS) cluster random sampling method. Prevalence of MS was defined under the diagnostic criteria of China Diabetes Society (CDS)...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231662/-a-cohort-study-on-the-epidemiological-characteristics-of-hbeag-sero-clearance-in-hbeag-positive-chronic-hepatitis-b-patients-in-jiangsu-province-from-2012-to-2014
#3
L G Zhu, J Jiang, C Song, Y Zou, J F Xu, H J Liu, H Peng, Z B Hu, F C Zhu, H B Shen, X J Zhai
Objective: To understand the epidemiological characteristics and influencing factors related to HBeAg sero-clearance in chronic hepatitis B patients so as to provide evidence for regular management on chronic HBV patients. Methods: From 2012 to 2014, a cohort study was conducted among HBeAg positive chronic HBV patients in Jiangsu province. Association between the characteristics and incidence of HBeAg sero-clearance was analyzed by Cox regression method. The changing trend on HBV DNA between patients with HBeAg sero-clearance and those with persistent HBeAg positive status was compared by repeated measure data variance analysis method...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231492/family-history-density-of-substance-use-problems-among-undergraduate-college-students-associations-with-heavy-alcohol-use-and-alcohol-use-disorder
#4
Gregory Powers, Lisa Berger, Daniel Fuhrmann, Michael Fendrich
PURPOSE: A family history of alcoholism has been found associated with problematic alcohol use among college students, but less research has examined the effects of family history density of substance use problems in this population. This study examined the prevalence of family history density of substance use problems and its associations with heavy alcohol use, negative alcohol consequences, and alcohol use disorder in a college sample. METHODS: Based on a secondary analysis of a probability sample, data were analyzed from 606 undergraduate students...
February 9, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28231441/risk-behaviours-for-organism-transmission-in-health-care-delivery-a-two-month-unstructured-observational-study
#5
Maria Lindberg, Magnus Lindberg, Bernice Skytt
BACKGROUND: Errors in infection control practices risk patient safety. The probability for errors can increase when care practices become more multifaceted. It is therefore fundamental to track risk behaviours and potential errors in various care situations. OBJECTIVE: The aim of this study was to describe care situations involving risk behaviours for organism transmission that could lead to subsequent healthcare-associated infections. DESIGN & SETTING: Unstructured nonparticipant observations were performed at three medical wards...
February 16, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28231421/varying-demographic-impacts-of-different-fisheries-on-three-mediterranean-seabird-species
#6
M Genovart, D Doak, J M Igual, S Sponza, J Kralj, D Oro
Fisheries have an enormous economic importance but reconciling their socio-economic features with the conservation and sustainability of marine ecosystems presents major challenges. Bycatch mortality from fisheries is clearly among the most serious global threats for marine ecosystems, affecting a wide range of top predators. Recent estimates report ca. 200,000 seabirds killed annually by bycatch in European waters. However there is an urgent need to rigorously estimate actual mortality rates and quantify effects of bycatch on populations...
February 23, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28231348/association-between-bone-graft-volume-and-maxillary-sinus-membrane-elevation-height
#7
Tetsuya Sonoda, Takehiro Harada, Nobuyuki Yamamichi, Alberto Monje, Hom-Lay Wang
PURPOSE: Maxillary sinus augmentation via crestal approach has been advocated as an alternative approach for sinus membrane elevation. Presently, no study has examined the relationship between the amount of bone grafting material placed and the final sinus membrane elevation height. Therefore, the present study was aimed at investigating the extent of sinus membrane elevation height depending on the amount of bone grafting material inserted as well as three-dimensionally assessing the likelihood of membrane perforation during membrane elevation...
February 23, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28231324/a-framework-for-analyzing-contagion-in-assortative-banking-networks
#8
Thomas R Hurd, James P Gleeson, Sergey Melnik
We introduce a probabilistic framework that represents stylized banking networks with the aim of predicting the size of contagion events. Most previous work on random financial networks assumes independent connections between banks, whereas our framework explicitly allows for (dis)assortative edge probabilities (i.e., a tendency for small banks to link to large banks). We analyze default cascades triggered by shocking the network and find that the cascade can be understood as an explicit iterated mapping on a set of edge probabilities that converges to a fixed point...
2017: PloS One
https://www.readbyqxmd.com/read/28231316/a-balanced-solution-to-the-cumulative-threat-of-industrialized-wind-farm-development-on-cinereous-vultures-aegypius-monachus-in-south-eastern-europe
#9
Dimitris P Vasilakis, D Philip Whitfield, Vassiliki Kati
Wind farm development can combat climate change but may also threaten bird populations' persistence through collision with wind turbine blades if such development is improperly planned strategically and cumulatively. Such improper planning may often occur. Numerous wind farms are planned in a region hosting the only cinereous vulture population in south-eastern Europe. We combined range use modelling and a Collision Risk Model (CRM) to predict the cumulative collision mortality for cinereous vulture under all operating and proposed wind farms...
2017: PloS One
https://www.readbyqxmd.com/read/28231242/predicting-ebola-infection-a-malaria-sensitive-triage-score-for-ebola-virus-disease
#10
Mary-Anne Hartley, Alyssa Young, Anh-Minh Tran, Harry Henry Okoni-Williams, Mohamed Suma, Brooke Mancuso, Ahmed Al-Dikhari, Mohamed Faouzi
BACKGROUND: The non-specific symptoms of Ebola Virus Disease (EVD) pose a major problem to triage and isolation efforts at Ebola Treatment Centres (ETCs). Under the current triage protocol, half the patients allocated to high-risk "probable" wards were EVD(-): a misclassification speculated to predispose nosocomial EVD infection. A better understanding of the statistical relevance of individual triage symptoms is essential in resource-poor settings where rapid, laboratory-confirmed diagnostics are often unavailable...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28231161/food-leftover-practices-among-consumers-in-selected-countries-in-europe-south-and-north-america
#11
Kadri Koppel, Federica Higa, Sandria Godwin, Nelson Gutierrez, Roman Shalimov, Paula Cardinal, Brizio Di Donfrancesco, Miriam Sosa, Angel A Carbonell-Barrachina, Loreida Timberg, Edgar Chambers
Foodborne illnesses may be related to many food production factors with home practices of consumers playing an important role in food safety. Consumer behavior for handling food leftovers has been studied, however little work on comparisons among countries has been published. The objective of this study was to investigate home food leftover practices of people from North American, South American, and European countries. Surveys were conducted with approximately 100 or more consumers in Argentina, Colombia, the United States, Estonia, Italy, Russia, and Spain...
September 21, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28231140/food-safety-recommendations-for-determining-doneness-in-consumer-egg-dish-recipes-and-measurement-of-endpoint-temperatures-when-recipes-are-followed
#12
Sandria Godwin, Curtis Maughan, Edgar Chambers
Many consumers do not follow recommended food safety practices for cooking egg dishes, such as pies, quiches, and casseroles, potentially leading to foodborne illnesses such as Salmonellosis. The United States Department of Agriculture (USDA) recommends cooking egg mixtures until the center reaches 71 °C (160 °F). The objectives of this study were to determine what endpoint temperature information consumers receive from egg dish recipes, and if recipes would lead to safe temperatures when followed. Egg dish recipes (n = 226) from 65 websites, 50 cookbooks, and nine magazine titles (multiple issues of each) were analyzed...
June 23, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28231029/unintended-insulin-pump-delivery-in-hyperbaric-conditions
#13
Federico Bertuzzi, Basilio Pintaudi, Matteo Bonomo, Fabio Garuti
AIMS/HYPOTHESIS: Unintended pump insulin delivery was reported to occur as a consequence of decreased atmospheric pressure, probably mediated by air bubble formation and the expansion of existing bubbles. This observation has been used to explain some hypoglycemic episodes occurring in patients on insulin pump treatment in between 1 and 1 h 45 min after the flight takeoff. New models of insulin pumps have been introduced in the market, most of them are waterproof certified. It is not clear if in these new pumps the influence of atmospheric pressure changes on the insulin delivery is still present...
February 23, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28231010/generation-of-anisotropic-massless-dirac-fermions-and-asymmetric-klein-tunneling-in-few-layer-black-phosphorus-superlattices
#14
Zhenglu Li, Ting Cao, Meng Wu, Steven G Louie
Artificial lattices have been employed in a broad range of two-dimensional systems, including those with electrons, atoms and photons, in the quest for massless Dirac fermions with high flexibility and controllability. Establishing triangular or hexagonal symmetry, from periodically patterned molecule assembly or electrostatic gating as well as from moiré pattern induced by substrate, has produced electronic states with linear dispersions from two-dimensional electron gas (2DEG) residing in semiconductors, metals and graphene...
February 23, 2017: Nano Letters
https://www.readbyqxmd.com/read/28230908/probiotics-for-people-with-hepatic-encephalopathy
#15
REVIEW
Rohan Dalal, Richard G McGee, Stephen M Riordan, Angela C Webster
BACKGROUND: Hepatic encephalopathy is a disorder of brain function as a result of liver failure or portosystemic shunt or both. Both hepatic encephalopathy (clinically overt) and minimal hepatic encephalopathy (not clinically overt) significantly impair patient's quality of life and daily functioning, and represent a significant burden on healthcare resources. Probiotics are live micro-organisms, which when administered in adequate amounts, may confer a health benefit on the host. OBJECTIVES: To determine the beneficial and harmful effects of probiotics in any dosage, compared with placebo or no intervention, or with any other treatment for people with any grade of acute or chronic hepatic encephalopathy...
February 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28230899/shared-care-across-the-interface-between-primary-and-specialty-care-in-management-of-long-term-conditions
#16
REVIEW
Susan M Smith, Gráinne Cousins, Barbara Clyne, Shane Allwright, Tom O'Dowd
BACKGROUND: Shared care has been used in the management of many chronic conditions with the assumption that it delivers better care than primary or specialty care alone; however, little is known about the effectiveness of shared care. OBJECTIVES: To determine the effectiveness of shared care health service interventions designed to improve the management of chronic disease across the primary/specialty care interface. This is an update of a previously published review...
February 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28230898/manifestations-and-medicolegal-significance-of-loeys-dietz-syndrome
#17
Roger W Byard
Loeys-Dietz syndrome is a recently described autosomal dominant disorder with underlying vasculopathy characterized by aortic and other vascular aneurysmal dissection/rupture. A 61-year-old man is reported who died suddenly and unexpectedly and at autopsy was found to have a ruptured abdominal aortic aneurysm. Additional findings included dolichostenomelia, high-arched palate, and pectus excavatum. There was a strong family history of Loeys-Dietz syndrome, although the decedent had never been tested. Death was, therefore, due to a ruptured abdominal aortic aneurysm in a case of probable Loeys-Dietz syndrome...
February 23, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28230773/programmed-death-ligand-1-pd-l1-tumor-expression-is-associated-with-a-better-prognosis-and-diabetic-disease-in-triple-negative-breast-cancer-patients
#18
Gerardo Botti, Francesca Collina, Giosuè Scognamiglio, Federica Rao, Valentina Peluso, Rossella De Cecio, Michela Piezzo, Gabriella Landi, Michelino De Laurentiis, Monica Cantile, Maurizio Di Bonito
Triple Negative Breast Cancers (TNBC) subtype is an aggressive disease with poor clinical outcome. The only treatment available is surgery followed by chemotherapy or radiotherapy. Programmed death-ligand 1 (PD-L1) is a trans-membrane protein expressed on a wide variety of cells including immune cells, epithelial and vascular endothelial cells. Recently, PD-1/PD-L1 pathway signaling was described as an adaptive immune resistance mechanism enacted by the tumor cells to evade the immune response. Its presence on tumor cell membranes, acquired for this reason, through time, is an important prognostic value...
February 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28230712/updating-evidence-for-using-hypothermia-in-pediatric-severe-traumatic-brain-injury-conventional-and-bayesian-meta-analytic-perspectives
#19
Robert C Tasker, Frederick W Vonberg, Elizabeth D Ulano, Alireza Akhondi-Asl
OBJECTIVE: To evaluate clinical trials of hypothermia management on outcome in pediatric patients with severe traumatic brain injury using conventional and Bayesian meta-analyses. DATA SOURCES: Screening of PubMed and other databases to identify randomized controlled trials of hypothermia for pediatric severe traumatic brain injury published before September 2016. STUDY SELECTION: Four investigators assessed and reviewed randomized controlled trial data...
February 20, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28230644/expanding-the-donor-pool-through-intensive-care-to-facilitate-organ-donation-results-of-a-spanish-multicenter-study
#20
Beatriz Domínguez-Gil, Elisabeth Coll, José Elizalde, Jaime E Herrero, Teresa Pont, Brígida Quindós, Bella Marcelo, María A Bodí, Adolfo Martínez, Agustín Nebra, Francisco Guerrero, José M Manciño, Juan Galán, Miguel Lebrón, Eduardo Miñambres, Rafael Matesanz
BACKGROUND: Intensive Care to facilitate Organ Donation (ICOD) may help to increase the donor pool. We describe the Spanish experience with ICOD. METHODS: ACCORD-Spain consisted of an audit of the donation pathway from patients dead as a result of a devastating brain injury (possible donors) in 68 hospitals during 11/1/2014-4/30/2015. We focused on possible donors whose family was interviewed to discuss organ donation once intensive care with a therapeutic purpose was deemed futile and brain death (BD) was a likely outcome...
February 23, 2017: Transplantation
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