Jing Xue, Xiaorong Li, Ping Liu, Ke Li, Liping Sha, Xiaoli Yang, Lili Zhu, Zhen Wang, Youping Dong, Li Zhang, Hong Lei, Xiaoxia Zhang, Xiaoying Dong, Hao Wang
Polycystic ovary syndrome (PCOS) represents an endocrine disorder, which is closely related with gut microbiota. Inulin, a kind of probiotics, has been proven to alleviate gut microbiota dysbiosis. Metformin, a biguanide agent, shows beneficial effects on chronic metabolic diseases. Our objective was to assess the effects and associated mechanisms of inulin and metforin on attenuation of PCOS in mice. Mice were divided into 4 groups: control group (CON), model group (MOD), inulin group (INU), metformin group (MET)...
October 28, 2019: Endocrine Journal