Marcele P Martins, Mariana A B Morais, Gabriela F Persinoti, Rafael H Galinari, Li Yu, Yoshihisa Yoshimi, Fernanda B Passos Nunes, Tatiani B Lima, Shayla F Barbieri, Joana L M Silveira, Vincent Lombard, Nicolas Terrapon, Paul Dupree, Bernard Henrissat, Mário T Murakami
Glycoside hydrolase family 5 (GH5) harbors diverse substrate specificities and modes of action, exhibiting notable molecular adaptations to cope with the stereochemical complexity imposed by glycosides and carbohydrates such as cellulose, xyloglucan, mixed-linkage β-glucan, laminarin, (hetero)xylan, (hetero)mannan, galactan, chitosan, N-glycan, rutin and hesperidin. GH5 has been divided into subfamilies, many with higher functional specificity, several of which have not been characterized to date and some that have yet to be discovered with the exploration of sequence/taxonomic diversity...
November 1, 2022: Acta Crystallographica. Section D, Structural Biology