keyword
MENU ▼
Read by QxMD icon Read
search

Diversity

keyword
https://www.readbyqxmd.com/read/29793170/effective-size-selection-of-mos-2-nanosheets-by-a-novel-liquid-cascade-centrifugation-influences-of-the-flakes-dimensions-on-electrochemical-and-photoelectrochemical-applications
#1
Marzieh Kajbafvala, Mansoor Farbod
Although liquid phase exfoliation is a powerful method to produce MoS2 nanosheets in large scale, but its effectiveness is limited by the diversity of produced nanosheets sizes. Here a novel approach for separation of MoS2 flakes having various lateral sizes and thicknesses based on the cascaded centrifugation has been introduced. This method involves a pre-separation step which is performed through low-speed centrifugation to avoid the deposition of large area single and few-layers by the heavier particles...
May 14, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29793140/effectiveness-of-a-voluntary-family-befriending-service-a-mixed-methods-evaluation-using-the-donabedian-model
#2
S V Gentry, E F J Powers, N Azim, M Maidrag
OBJECTIVES: Voluntary befriending schemes operate in many countries, promoting public health by supporting vulnerable individuals and families. Use of third sector and voluntary services to complement health and social care provision is increasingly important globally in the context of economic and demographic challenges, but the evidence base around such collaborations is limited. This article reports the results of operational evaluation research seeking to use robust routine work to generate transferable findings for use by those commissioning and providing services...
May 21, 2018: Public Health
https://www.readbyqxmd.com/read/29792990/identification-of-group-a-rotaviruses-from-zambian-fruit-bats-provides-evidence-for-long-distance-dispersal-events-in-africa
#3
Michihito Sasaki, Masahiro Kajihara, Katendi Changula, Akina Mori-Kajihara, Hirohito Ogawa, Bernard M Hang'ombe, Aaron S Mweene, Martin Simuunza, Reiko Yoshida, Michael Carr, Yasuko Orba, Ayato Takada, Hirofumi Sawa
Group A rotavirus (RVA) is a major cause of diarrhea in children worldwide. Although RVA infects many animals, little is known about RVA in bats. The present study investigated the genetic diversity of RVA in Zambian bats. We identified RVA from two straw-colored fruit bats (Eidolon helvum) and an Egyptian fruit bat (Rousettus aegyptiacus), and analyzed the genome sequences of these strains. Genome segments of the RVA strains from Zambian E. helvum showed 97%-99% nucleotide sequence identity with those of other RVA strains from E...
May 21, 2018: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29792942/optimisation-of-decontamination-method-and-influence-of-culture-media-on-the-recovery-of-mycobacterium-avium-subspecies-paratuberculosis-from-spiked-water-sediments
#4
G Aboagye, M T Rowe
The recovery of Mycobacterium avium subspecies paratuberculosis (Map) from the environment can be a laborious process - owing to Map being fastidious, its low number, and also high numbers of other microbial populations in such settings. Protocols i.e. filtration, decontamination and modified elution were devised to recover Map from spiked water sediments. Three culture media: Herrold's Egg Yolk Media (HEYM), Middlebrook 7H10 (M-7H10) and Bactec 12B were then employed to grow the organism following its elution...
May 21, 2018: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/29792909/dermatofibrosarcoma-protuberans-a-retrospective-study-of-clinicopathological-features-and-related-akt-mtor-stat3-erk-cyclin-d1-and-pd-l1-expression
#5
Sunyoung Park, Soyun Cho, Minji Kim, Ji Ung Park, Eui Cheol Jeong, Euno Choi, Jeong Hwan Park, Cheol Lee, Mee Soo Chang
BACKGROUND: Little is known regarding oncoproteins other than PDGFβ in dermatofibrosarcoma protuberance (DFSP). Moreover, the risk factors for worse prognosis are controversial. OBJECTIVE: We sought to determine the clinicopathological features and key factors for adverse outcome in DFSP including the implication of Akt/mTOR, STAT3, ERK, cyclinD1, and PD-L1 expression. METHODS: Clinicopathological and immunohistochemical analyses were performed for 44 DFSPs having wide local excision along with 92 dermatofibromas as controls...
May 21, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29792855/the-versatile-hippo-pathway-in-oral-maxillofacial-development-and-bone-remodeling
#6
REVIEW
Lin Xiang, Hui Yu, Xinyuan Zhang, Bin Wang, Ying Yuan, Qin Zhang, Rui Ye, Ping Gong, Yingying Wu
The Hipposignaling pathway is implicated in key aspects of cell proliferation, control of organ size, stem cell functions and tumor suppression. Its functions are primarily mediated either through direct effects on transcription factors to influence target gene expression or through crosstalk with other signaling pathways that regulate multiple physiological activities. Studies are revealing Hippo pathway involvement in diverse functions including renewal of intestinal epithelium, promotion of myocardial cell proliferation, cancer suppression, etc...
May 21, 2018: Developmental Biology
https://www.readbyqxmd.com/read/29792822/genetic-identity-in-genebanks-application-of-the-solcap-12k-snp-array-in-fingerprinting-and-diversity-analysis-in-the-global-in-trust-potato-collection
#7
David Ellis, Oswaldo Chavez, Joseph J Coombs, Julian V Soto, Rene Gomez, David S Douches, Ana Panta, Rocio Silvestre, Noelle Lynette Anglin
Breeders rely on genetic integrity of material from genebanks, however, mislabeling and errors in original data can occur. Paired samples of original material and their in vitro counterparts from 250 diverse potato landrace accessions from the International Potato Center (CIP), were fingerprinted using the Infinium 12K V2 Potato Array to confirm genetic identity and evaluate genetic diversity. Diploid, triploid, and tetraploid accessions were included representing seven cultivated potato taxa (Hawkes, 1990)...
May 24, 2018: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/29792805/a-cheminformatic-insight-into-the-differences-between-terrestrial-and-marine-originated-natural-products
#8
Jun Shang, Ben Hu, Junmei Wang, Feng Zhu, Yu Kang, Dan Li, Huiyong Sun, De-Xin Kong, Tingjun Hou
This is a new golden age for the drug discovery based on natural products derived from both marine and terrestrial sources. Herein, a straightforward but important question is what are the major structural differences between marine natural products (MNPs) and terrestrial natural products (TNPs). To answer this question, we analyzed the important physicochemical properties, structural features and drug-likeness of the two types of natural products and discussed their differences from the perceptive of evolution...
May 24, 2018: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/29792801/developing-a-novel-sulfoxide-containing-ms-cleavable-homobifunctional-cysteine-reactive-cross-linker-for-studying-protein-protein-interactions
#9
Craig B Gutierrez, Sarah A Block, Clinton Yu, Stephanie M Soohoo, Alexander S Huszagh, Scott D Rychnovsky, Lan Huang
Cross-linking mass spectrometry (XL-MS) has become an emerging technology for defining protein-protein interactions (PPIs) and elucidating architectures of large protein complexes. Up to now, the mostly widely used cross-linking reagents are targeting lysines. While such reagents have been successfully applied to map PPIs at the proteome-wide scale, comprehensive PPI profiling would require additional cross-linking chemistries. Cysteine is one of the most reactive amino acids and an attractive target for cross-linking owing to its unique role in protein structures...
May 24, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29792712/targeted-discovery-and-combinatorial-biosynthesis-of-polycyclic-tetramate-macrolactam-combamides-a-e
#10
Yan Liu, Haoxin Wang, Rentai Song, Jining Chen, Tianhong Li, Yaoyao Li, Liangcheng Du, Yuemao Shen
Polycyclic tetramate macrolactams (PoTeMs) are a growing class of natural products with distinct structure and diverse biological activities. By promoter engineering and heterologous expression of the cryptic cbm gene cluster, four new PoTeMs, combamides A-E (1-4), were identified. Additionally, two new derivatives, combamides E (5) and F (6), were generated via combinatorial biosynthesis. Together, our findings provide a sound base for expanding the structure diversities of PoTeMs through genome mining and combinatorial biosynthesis...
May 24, 2018: Organic Letters
https://www.readbyqxmd.com/read/29792672/biosynthesis-of-lincosamide-antibiotics-reactions-associated-with-degradation-and-detoxification-pathways-play-a-constructive-role
#11
Daozhong Zhang, Zhijun Tang, Wen Liu
Natural products typically are small molecules produced by living organisms. These products possess a wide variety of biological activities and thus have historically played a critical role in medicinal chemistry and chemical biology either as chemotherapeutic agents or as useful tools. Natural products are not synthesized for use by human beings; rather, living organisms produce them in response to various biochemical processes and environmental concerns, both internal and external. These processes/concerns are often dynamic and thus motivate the diversification, optimization, and selection of small molecules in line with changes in biological function...
May 24, 2018: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29792597/increasing-plant-diversity-with-border-crops-reduces-insecticide-use-and-increases-crop-yield-in-urban-agriculture
#12
Nian-Feng Wan, You-Ming Cai, Yan-Jun Shen, Xiang-Yun Ji, Xiang-Wen Wu, Xiang-Rong Zheng, Wei Cheng, Jun Li, Yao-Pei Jiang, Xin Chen, Jacob Weiner, Jie-Xian Jiang, Ming Nie, Rui-Ting Ju, Tao Yuan, Jian-Jun Tang, Wei-Dong Tian, Hao Zhang, Bo Li
Urban agriculture is making an increasing contribution to food security in large cities around the world. The potential contribution of biodiversity to ecological intensification in urban agricultural systems has not been investigated. We present monitoring data collected from rice fields in 34 community farms in mega-urban Shanghai, China, from 2001 to 2015, and show that the presence of a border crop of soybeans and neighboring crops (maize, eggplant and Chinese cabbage), both without weed control, increased invertebrate predator abundance, decreased the abundance of pests and dependence on insecticides, and increased grain yield and economic profits...
May 24, 2018: ELife
https://www.readbyqxmd.com/read/29792591/comprehensive-evolutionary-and-phylogenetic-analysis-of-hepacivirus-n-hnv
#13
M S da Silva, D M Junqueira, L F Baumbach, S P Cibulski, A C S Mósena, M N Weber, S Silveira, G M de Moraes, R D Maia, V C S Coimbra, C W Canal
Hepaciviruses (HVs) have been detected in several domestic and wild animals and present high genetic diversity. The actual classification divides the genus Hepacivirus into 14 species (A-N), according to their phylogenetic relationships, including the bovine hepacivirus [Hepacivirus N (HNV)]. In this study, we confirmed HNV circulation in Brazil and sequenced the whole genome of two strains. Based on the current classification of HCV, which is divided into genotypes and subtypes, we analysed all available bovine hepacivirus sequences in the GenBank database and proposed an HNV classification...
May 24, 2018: Journal of General Virology
https://www.readbyqxmd.com/read/29792562/combined-effects-and-cross-interactions-of-different-antibiotics-and-polypeptides-in-salmonella-bredeney
#14
Xiangyu Ju, Mengjiao Zhu, Jinzhi Han, Zhaoxin Lu, Haizhen Zhao, Xiaomei Bie
Salmonella spp. are health-threatening foodborne pathogens. The increasingly common spread of antibiotic-resistant Salmonella spp. is a major public healthcare issue worldwide. In this study, we wished to explore (1) antibiotic or polypeptide combinations to inhibit multidrug-resistant Salmonella bredeney and (2) the regulation of cross-resistance and collateral sensitivity of antibiotics and polypeptides. We undertook a study to select antibiotic combinations. Then, we promoted drug-resistant strains of S...
May 24, 2018: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/29792514/a-flow-procedure-for-linearization-of-genome-sequence-graphs
#15
David Haussler, Maciej Smuga-Otto, Jordan M Eizenga, Benedict Paten, Adam M Novak, Sergei Nikitin, Maria Zueva, Dmitrii Miagkov
Efforts to incorporate human genetic variation into the reference human genome have converged on the idea of a graph representation of genetic variation within a species, a genome sequence graph. A sequence graph represents a set of individual haploid reference genomes as paths in a single graph. When that set of reference genomes is sufficiently diverse, the sequence graph implicitly contains all frequent human genetic variations, including translocations, inversions, deletions, and insertions. In representing a set of genomes as a sequence graph, one encounters certain challenges...
May 24, 2018: Journal of Computational Biology: a Journal of Computational Molecular Cell Biology
https://www.readbyqxmd.com/read/29792494/fostering-youth-self-efficacy-to-address-transgender-and-racial-diversity-issues-the-role-of-gay-straight-alliances
#16
Eddie S K Chong, V Paul Poteat, Hirokazu Yoshikawa, Jerel P Calzo
Gay-Straight Alliances (GSAs) aspire to empower youth to address multiple systems of oppression, including those affecting transgender and racial/ethnic minority youth, yet there is little indication of factors contributing to youths' self-efficacy to do so. We examined individual and group factors predicting self-efficacy to address transgender and racial issues among 295 youth in 33 high school GSAs. Multilevel results indicated that level of GSA engagement, individual and collective involvement in transgender- and race-specific discussions, and in some cases intergroup friendships were associated with each form of self-efficacy...
May 24, 2018: School Psychology Quarterly
https://www.readbyqxmd.com/read/29792489/what-it-means-to-be-a-national-a-study-among-adolescents-in-multicultural-mauritius
#17
Femke van der Werf, Maykel Verkuyten, Borja Martinovic, Caroline Ng Tseung-Wong
OBJECTIVES: We investigated adolescents' understandings of national group membership in multicultural Mauritius. We hypothesized that tolerance toward different cultures would be an important criterion for being Mauritian. In addition, national identity was expected to be defined in terms of "being," "feeling," and "doing." The type of definition, and whether stopping being Mauritian is perceived as possible, was expected to depend on age and national identification...
May 24, 2018: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/29792481/risk-and-protective-factors-of-intimate-partner-violence-among-south-asian-immigrant-women-and-perceived-need-for-services
#18
Bushra Sabri, Michelle Simonet, Jacquelyn C Campbell
OBJECTIVES: Limited research exists on multilevel influences of intimate partner violence (IPV) among immigrant groups in the United States, particularly South Asians. Using a socioecological framework, this study examined risk and protective factors of IPV among a diverse group of South Asian immigrant survivors of IPV and identified their perceived need for services. METHOD: Sixteen South Asian immigrant survivors were recruited from New York; Maryland; Virginia; and Washington, DC, using a snowball sampling method...
May 24, 2018: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/29792475/the-alliance-in-adult-psychotherapy-a-meta-analytic-synthesis
#19
Christoph Flückiger, A C Del Re, Bruce E Wampold, Adam O Horvath
The alliance continues to be one of the most investigated variables related to success in psychotherapy irrespective of theoretical orientation. We define and illustrate the alliance (also conceptualized as therapeutic alliance, helping alliance, or working alliance) and then present a meta-analysis of 295 independent studies that covered more than 30,000 patients (published between 1978 and 2017) for face-to-face and Internet-based psychotherapy. The relation of the alliance and treatment outcome was investigated using a three-level meta-analysis with random-effects restricted maximum-likelihood estimators...
May 24, 2018: Psychotherapy
https://www.readbyqxmd.com/read/29792460/the-complexity-diversity-and-science-of-primary-care-teams
#20
Kevin Fiscella, Susan H McDaniel
This article examines the past, present and future of primary care and teamwork. It begins with a definition and description of primary care-its uniqueness, diversity and complexity, including the historical role of teams within primary care. The article then reviews the emergence of innovative primary care teams, including those grounded in new processes such as the Patient-Centered Medical Home and interprofessional teams that include new types of health professionals, particularly psychologists and other integrated behavioral health clinicians...
May 2018: American Psychologist
keyword
keyword
35178
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"