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https://www.readbyqxmd.com/read/29149745/household-air-pollution-and-chronic-hypoxia-in-the-placenta-of-pregnant-nigerian-women-a-randomized-controlled-ethanol-cookstove-intervention
#1
Anindita Dutta, Galina Khramstova, Katherine Brito, Donee Alexander, Ariel Mueller, Sireesha Chinthala, Damilola Adu, Tope Ibigbami, John Olamijulo, Abayomi Odetunde, Kehinde Adigun, Liese Pruitt, Ian Hurley, Olufunmilayo Olopade, Oladosu Ojengbede, Sarosh Rana, Christopher O Olopade
BACKGROUND: Household air pollution (HAP) is associated with adverse pregnancy outcomes. OBJECTIVES: Investigate impact of in-utero HAP exposure on placental development and chronic hypoxia. METHODS: Markers of chronic placental hypoxia [Hofbauer cells (HBC), syncytial knots (SK), chorionic vascular density (cVD) and hypoxia-inducible factor (HIF)] were stained by hematoxylin-eosin and/or immunohistochemically in placenta samples collected from firewood-/kerosene-users (A,n=16), and ethanol-users (B,n=20) that participated in a randomized controlled intervention trial in Ibadan, Nigeria...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29146255/haemophilus-parasuis-cpxra-two-component-system-confers-bacterial-tolerance-to-environmental-stresses-and-macrolide-resistance
#2
Qi Cao, Fenfen Feng, Huan Wang, Xiaojuan Xu, Huanchun Chen, Xuwang Cai, Xiangru Wang
Haemophilus parasuis is an opportunistic pathogen localized in the upper respiratory tracts of pigs, its infection begins from bacterial survival under complex conditions, like hyperosmosis, oxidative stress, phagocytosis, and sometimes antibiotics as well. The two-component signal transduction (TCST) system serves as a common stimulus-response mechanism that allows microbes to sense and respond to diverse environmental conditions via a series of phosphorylation reactions. In this study, we investigated the role of TCST system CpxRA in H...
January 2018: Microbiological Research
https://www.readbyqxmd.com/read/29143139/effect-of-protein-adsorption-layers-and-solution-treatments-on-hydroxyapatite-deposition-on-polystyrene-plate-surfaces-in-simulated-body-fluids
#3
Kazutoshi Iijima, Ayako Iizuka, Ryo Suzuki, Hitomi Ueno-Yokohata, Nobutaka Kiyokawa, Mineo Hashizume
We have developed a method to functionalize polystyrene (PS) cell culture plates with hydroxyapatite (HAp) via protein adsorption layers such as human serum albumin (HSA) in simulated body fluids (SBFs). In order to investigate the versatility the method, in this study the effect of protein adsorption layers on HAp deposition on PS plate surfaces in SBF was evaluated. Pretreatments with alternate soaking process (ASP) using solutions containing calcium ions and phosphate ions followed by incubation with SBF for 24 h resulted in HAp deposition on PS plates with adsorption layers of HSA, type I collagen, hen egg white lysozyme, and poly L-glutamic acid, an acidic protein analogue: the deposition behaviors were correlated with adsorption ability and charge state of proteins...
November 15, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/29141157/the-devastating-effect-of-exposure-to-high-irradiation-dose-on-liver-and-the-performance-of-synthesized-nano-hap-in-relieve-the-associated-symptoms-in-rats
#4
Eman Ismail Gheriany, Sameh A Awwad
Ionizing radiation is one of the environmental factors that may contribute to liver dysfunction by a mechanism involving oxidative stress. The present investigation was undertaken to study the possible therapeutic effect of nano-HAp on whole body gamma irradiation induced hepatotoxicity in rats. The study consisted of three groups of 10 rats each. Group 1 (control), whereas group 2 received a single dose of γ-radiation (10Gy). The animals in groups 3 was treated with nano-HAp (100 mg/kg b.w.) once / week for three weeks starting in the next day of γ radiation...
November 15, 2017: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/29140181/rational-design-of-a-high-strength-bone-scaffold-platform-based-on-in-situ-hybridization-of-bacterial-cellulose-nano-hydroxyapatite-framework-and-silk-fibroin-reinforcing-phase
#5
Pei Jiang, Jiabing Ran, Pan Yan, Lingyue Zheng, Xinyu Shen, Hua Tong
Bacterial cellulose/hydroxyapatite (BC/HAp) composite had favourable bioaffinity but its poor mechanical strength limited its widespread applications in bone tissue engineering (BTE). Silk fibroin, which possesses special crystalline structure, has been widely used as organic reinforcing material, and different SFs have different amino acid sequences, which exhibit different bioaffinity and mechanical properties. In this regard, bacterial cellulose-Antheraea yamamai silk fibroin/hydroxyapatite(BC-AYSF/HAp), bacterial cellulose-Bombyx mori silk fibroin/hydroxyapatite(BC-BMSF/HAp), and BC/HAp nano-composites were synthesized via a novel in situ hybridization method...
November 15, 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/29138638/tissue-source-and-cell-expansion-condition-influence-phenotypic-changes-of-adipose-derived-stem-cells
#6
Lauren H Mangum, Shanmugasundaram Natesan, Randolph Stone, Nicole L Wrice, David A Larson, Kyle F Florell, Barbara A Christy, Maryanne C Herzig, Andrew P Cap, Robert J Christy
Stem cells derived from the subcutaneous adipose tissue of debrided burned skin represent an appealing source of adipose-derived stem cells (ASCs) for regenerative medicine. Traditional tissue culture uses fetal bovine serum (FBS), which complicates utilization of ASCs in human medicine. Human platelet lysate (hPL) is one potential xeno-free, alternative supplement for use in ASC culture. In this study, adipogenic and osteogenic differentiation in media supplemented with 10% FBS or 10% hPL was compared in human ASCs derived from abdominoplasty (HAP) or from adipose associated with debrided burned skin (BH)...
2017: Stem Cells International
https://www.readbyqxmd.com/read/29138583/efficacy-of-intravenous-tigecycline-in-patients-with-acinetobacter-complex-infections-results-from-14-phase-iii-and-phase-iv-clinical-trials
#7
Hal Tucker, Michele Wible, Ashesh Gandhi, Alvaro Quintana
Background: Acinetobacter infections, especially multidrug-resistant (MDR) Acinetobacter infections, are a global health problem. This study aimed to describe clinical outcomes in patients with confirmed Acinetobacter spp. isolates who were treated with tigecycline in randomized clinical trials. Materials and methods: Data from 14 multinational, randomized (open-label or double-blind), and active-controlled (except one) Phase III and IV studies were analyzed using descriptive statistics...
2017: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29134339/feline-immudeficiency-virus-subtypes-b-and-a-in-cats-from-s%C3%A3-o-luis-maranh%C3%A3-o-brazil
#8
Nathálya Dos S Martins, Ana Paula de S Rodrigues, Luciana A da Luz, Luana da L Dos Reis, Renata M de Oliveira, Rudson A de Oliveira, Ana Lucia Abreu-Silva, Jenner Karlisson P Dos Reis, Ferdinan A Melo
Feline immunodeficiency virus (FIV) is a retrovirus of the genus Lentivirus that is distributed worldwide, with prevalence rates varying between 2.5% and 44%. FIV causes immunosuppression, with depletion of TCD4(+) lymphocytes, with the majority of clinical signs caused by secondary and opportunistic infections. Blood samples were collected from nine domestic cats (Felis catus domesticus) from the city of São Luís, Maranhão State, Brazil. All samples were positive in a rapid immunochromatographic test (SNAP® Combo FeLV Ag/FIV Antibody Test) and in a polymerase chain reaction (PCR) assay...
November 14, 2017: Archives of Virology
https://www.readbyqxmd.com/read/29132437/hap2-a-novel-gene-in-babesia-bigemina-is-expressed-in-tick-stages-and-specific-antibodies-block-zygote-formation
#9
Minerva Camacho-Nuez, Diego Josimar Hernández-Silva, Elizabeth Jacqueline Castañeda-Ortiz, María Elena Paredes-Martínez, Marisol Karina Rocha-Martínez, María Elizbeth Alvarez-Sánchez, Ricardo Francisco Mercado-Curiel, Gabriela Aguilar-Tipacamu, Juan Mosqueda
BACKGROUND: Bovine babesiosis is a tick-borne disease caused by the protozoan parasites of the genus Babesia. In their host vector, Babesia spp. undergo sexual reproduction. Therefore, the development of sexual stages and the subsequent formation of the zygote are essential for the parasite to invade the intestinal cells of the vector tick and continue its life-cycle. HAP2/GCS1 is a protein identified in plants, protozoan parasites and other organisms that has an important role during membrane fusion in fertilization processes...
November 13, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29132418/indoor-air-pollution-from-secondhand-tobacco-smoke-solid-fuels-and-kerosene-in-homes-with-active-tuberculosis-disease-in-south-africa
#10
Jessica L Elf, Onyinyechi Eke, Modiehi Rakgokong, Ebrahim Variava, Yudesh Baliram, Katlego Motlhaoleng, Limakatso Lebina, Adrienne E Shapiro, Patrick N Breysse, Jonathan E Golub, Neil Martinson
OBJECTIVES: Secondhand tobacco smoke (SHS), use of solid fuels, and kerosene may play an important role in perpetuating the tuberculosis (TB) epidemic. The purpose of this study was to explore the prevalence of household air pollution (HAP) from these sources in homes of someone with TB in a high HIV-prevalence setting. A convenience sample of homes and household members participating in an ongoing active case-finding study in Matlosana district townships surrounding Klerksdorp, South Africa were included...
November 13, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29132238/nanomicelle-drug-with-acid-triggered-doxorubicin-release-and-enhanced-cellular-uptake-ability-based-on-mpeg-graft-poly-n-2-aminoethyl-l-aspartamide-hexahydrophthalic-acid-copolymers
#11
Li Cao, Yi Xiao, Wei Lu, Shiyuan Liu, Lin Gan, Jiahui Yu, Jin Huang
In order to achieve the passive tumor targeting and acid-triggered drugs release in lysosomes, optimized delivery system for doxorubicin based on pH-sensitive complex nanomicelles with suitable particle size was developed in this research. Particularly, poly(L-succinimide) was thoroughly ring-opened by ethylenediamine to give the poly(N-(2-aminoethyl)-L-aspartamide). Then, graft copolymer mPEG-graft-poly(N-(2-aminoethyl)-L-aspartamide)-hexahydrophthalic acid (mPEG-g-P(ae-Asp)-Hap) was synthesized by grafting mPEG-2000 and hexahydrophthalic anhydride onto poly(N-(2-aminoethyl)-L-aspartamide)...
January 1, 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/29126531/cap-hcap-hap-%C3%A2-vap-the-diachronic-linguistics-of%C3%A2-pneumonia
#12
EDITORIAL
Jason P Burnham, Marin H Kollef
No abstract text is available yet for this article.
November 2017: Chest
https://www.readbyqxmd.com/read/29109809/automated-axis-alignment-for-a-nanomanipulator-inside-sem-and-its-error-optimization
#13
Chao Zhou, Lu Deng, Long Cheng, Zhiqiang Cao, Shuo Wang, Min Tan
In the motion of probing nanostructures, repeating position and movement is frequently happing and tolerance for position error is stringent. The consistency between the axis of manipulators and image is very significant since the visual servo is the most important tool in the automated manipulation. This paper proposed an automated axis alignment method for a nanomanipulator inside the SEM by recognizing the position of a closed-loop controlling the end-effector, which can characterize the relationship of these two axes, and then the rotation matrix can be calculated accordingly...
2017: Scanning
https://www.readbyqxmd.com/read/29109556/management-of-mechanical-ventilation-in-patients-with-hospital-acquired-pneumonia-a-retrospective-observational-study
#14
Radovan Uvizl, Tomas Herkel, Katerina Langova, Petr Jakubec
BACKGROUND: Hospital-acquired pneumonia (HAP) in intensive care patients is a frequent reason for mechanical ventilation (MV). The management of MV and ventilator weaning vary, depending on the type of lung inflammation. This retrospective, observational study screened the data from all patients admitted to the intensive care unit (ICU) of the Department of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc between 2011 and 2016...
November 2, 2017: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/29109310/in-situ-effect-of-nanohydroxyapatite-paste-in-enamel-teeth-bleaching
#15
Yasmin Sb de Lima Gomes, Larissa D Alexandrino, Cristiane de M Alencar, Eliane B Alves, Kelson Cf Faial, Cecy M Silva
AIM: Evaluate in situ the effect of nanohydroxyapatite paste (nano-HAP) before bleaching with hydrogen peroxide 35% (HP35%) by ion chromatography (IC) Knoop hardness number (KHN) and tristimulus colorimetry (TC). MATERIALS AND METHODS: A total of 60 fragments were obtained from third molars included (3 mm × 3 mm × 3 mm) and the specimens were divided into three groups (n = 20): Gas chromatography (CG) (negative control group) = no bleaching; HP35% (positive control group) = HP35% whitening (whiteness HP35%); nano-HAP = application for 10 minutes before bleaching treatment + HP35%...
November 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29107891/elevated-blood-pressure-and-household-solid-fuel-use-in-premenopausal-women-analysis-of-12-demographic-and-health-surveys-dhs-from-10-countries
#16
Raphael E Arku, Majid Ezzati, Jill Baumgartner, Günther Fink, Bin Zhou, Perry Hystad, Michael Brauer
BACKGROUND: Approximately three billion people are exposed to household air pollution (HAP) from solid fuel cookstoves. Studies from single settings have linked HAP with elevated blood pressure (BP), but no evidence exists from multi-country analyses. OBJECTIVES: Using nationally representative and internationally comparable data, we examined the association between solid fuel use and BP in 77,605 largely premenopausal women (aged 15-49) from ten resource-poor countries...
November 5, 2017: Environmental Research
https://www.readbyqxmd.com/read/29106671/palivizumab-for-infants-%C3%A2-29-weeks-in-hong-kong-without-a-clear-cut-season-for-respiratory-syncytial-virus-infection-a-cost-effectiveness-analysis
#17
Shing-Yan Robert Lee, Ka Li Kwok, Daniel Kwok Keung Ng, Kam Lun Hon
Aim: To evaluate the cost-effectiveness of palivizumab prophylaxis for premature infants born <29 weeks in Hong Kong. Method: We evaluated the hospitalization rate for respiratory syncytial virus (RSV) infection within the first 12 months of discharge of a cohort of preterm infants born between 2010 and 2014 at two local hospitals. Results: In total, 40 of 135 infants were given palivizumab. The hospitalization rate for premature infants <29 weeks was reduced from 15...
November 2, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29103979/comparison-of-microvascular-perfusion-evaluation-among-ivim-dwi-ct-perfusion-imaging-and-histological-microvessel-density-in-rabbit-liver-vx2-tumors
#18
Jing-Lei Li, Wei-Tao Ye, Zai-Yi Liu, Li-Fen Yan, Wei Luo, Xi-Ming Cao, Changhong Liang
OBJECT: To explore microcirculation features with intravoxel incoherent motion (IVIM) and to compare IVIM with CT perfusion imaging (CTPI) and microvessel density (MVD). MATERIALS AND METHODS: Hepatic CTPI and IVIM were performed in 16 rabbit liver VX2 tumor models. Hepatic arterial perfusion (HAP), hepatic arterial perfusion index (HPI), Blood flow (BF), and blood volume (BV) from CTPI were measured. Apparent diffusion coefficient (ADC), true diffusion coefficient (D), perfusion fraction (f), and pseudo-diffusion coefficient (D*) from IVIM were measured...
November 9, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29101870/enhanced-biological-properties-of-biomimetic-apatite-fabricated-polycaprolactone-chitosan-nanofibrous-bio-composite-for-tendon-and-ligament-regeneration
#19
Geng Wu, Xuefeng Deng, Jinqi Song, Feiqiang Chen
The development of tailored nanofibrous scaffolds for tendon and ligament tissue engineering has been a goal of clinical research for current researchers. Here, we establish a formation of novel nanofibrous matrix with significant mechanical and biological properties by electro-spinning process. The fine fibrous morphology of the nanostructured hydroxyapatite (HAp) dispersed in the polycaprolactone/chitosan (HAp-PCL/CS) nanofibrous matrix was exhibited by microscopic (SEM and TEM) techniques. The favorable mechanical properties (load and modulus) were achieved...
October 7, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29098204/sexual-orientation-gender-and-environmental-injustice-unequal-carcinogenic-air-pollution-risks-in-greater-houston
#20
Timothy W Collins, Sara E Grineski, Danielle X Morales
Disparate residential hazard exposures based on disadvantaged gender status (e.g., among female-headed households) have been documented in the distributive environmental justice literature, yet no published studies have examined whether disproportionate environmental risks exist based on minority sexual orientation. To address this gap, we use data from the US Census, American Community Survey and the Environmental Protection Agency at the 2010 census tract level to examine the spatial relationships between same-sex partner households and cumulative cancer risk from exposure to hazardous air pollutants (HAPs) emitted by all ambient emission sources in Greater Houston (Texas)...
2017: Annals of the American Association of Geographers
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