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Sensorineural hearing loss

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https://www.readbyqxmd.com/read/29227458/unilateral-sensorineural-hearing-loss-associated-with-vertebrobasilar-dolichoectasia
#1
Reed C Gilbow, Douglas S Ruhl, George T Hashisaki
No abstract text is available yet for this article.
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29227450/hearing-loss-in-pediatric-patients-with-cerebral-palsy
#2
Forest W Weir, Jonathan L Hatch, Theodore R McRackan, Sarah A Wallace, Ted A Meyer
OBJECTIVE: This study evaluates the prevalence, type, and severity of hearing impairment in children with cerebral palsy (CP) and to analyze audiologic and otologic outcomes in these patients. STUDY DESIGN: Retrospective analysis of the AudGen Database. SETTING: Tertiary academic referral center. PATIENTS: Pediatric patients in AudGen Database with a diagnosis of cerebral palsy. Appropriate audiologic, otologic, and demographic data were recorded...
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29227445/mobile-hearing-testing-applications-and-the-diagnosis-of-sudden-sensorineural-hearing-loss-a-cautionary-tale
#3
Rosh K V Sethi, Iman Ghanad, Vivek Kanumuri, Barbara Herrmann, Elliott D Kozin, Aaron K Remenschneider
OBJECTIVE: Mobile hearing applications (apps) are available for hearing testing, personal sound amplification, as well as hearing aid modulation. Hearing testing apps are gaining popularity, especially in resource-limited settings. The reliability of mobile hearing testing apps, however, is not well characterized. PATIENTS/INTERVENTIONS: A case study of a single patient with a complaint of sudden hearing loss presenting to a tertiary-care hospital. MAIN OUTCOME MEASURE: Comparison of a mobile hearing testing app results with standard audiogram...
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29224848/anti-mumps-igm-antibody-positive-rate-with-sudden-sensorineural-hearing-loss-using-second-generation-enzyme-immunoassay-a-retrospective-multi-institutional-investigation-in-hokkaido-japan
#4
Atsushi Fukuda, Shinya Morita, Yuji Nakamaru, Kimiko Hoshino, Keishi Fujiwara, Shigeru Akazawa, Tomohiro Sakashita, Nobuyuki Obara, Akihiro Homma
OBJECTIVE: Although elevated anti-mumps IgM antibody levels were reported in 5.7%-7.2% of Japanese patients with sudden sensorineural hearing loss (SSNHL), there were several reports of false-positive cases, such as the continually IgM positive case and the IgM positive case in normal adults. To improve specificity, the new enzyme immuno assay (EIA) anti-mumps IgM antibody measurement kit was introduced in December 2009. This study re-examined the frequency of anti-mumps IgM antibody test positivity with SSNHL using the new measurement kit and compared the results with those from a previous report that used old kit...
December 7, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29224766/reversible-profound-sensorineural-hearing-loss-due-to-propranolol-sensitive-hemangioma-in-an-infant-with-phace-syndrome
#5
John N Bangiyev, Richard Gurgel, Sheryll L Vanderhooft, J Fredrik Grimmer
PHACE syndrome is the association of large or segmental infantile hemangiomas of the face or scalp with abnormalities within the posterior fossa, arteries, cardiovascular system, and eyes. We present a case of reversible profound sensorineural hearing loss due to a cerebellopontine angle infantile hemangioma that was successfully treated with propranolol.
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29224747/next-generation-sequencing-identifies-three-novel-missense-variants-in-ildr1-and-myo6-genes-in-an-iranian-family-with-hearing-loss-with-review-of-the-literature
#6
Farah Talebi, Farideh Ghanbari Mardasi, Javad Mohammadi Asl, Masoomeh Sayahi
OBJECTIVES: Hearing impairment is the most common sensorineural disorder and is genetically heterogeneous. Identification of the pathogenic mutations underlying hearing impairment is difficult, since causative mutations in 127 different genes have so far been reported. METHODS: In this study, we performed Next-generation sequencing (NGS) in 2 individuals from a consanguineous family with hearing loss. RESULTS: Three novel mutations in known deafness genes were identified in the family; MYO6-p...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29222679/-objective-audiometry-and-clinical-application
#7
M Cebulla, D Ehrmann-Müller, W Shehata-Dieler
Subjective and objective hearing tests are used for evaluation of hearing impairments. Objective methods include impedance measurement with tympanometry and stapedius reflex measurement, otoacoustic emissions (OAE), and auditory evoked potentials (AEP). Combined with statistical analysis, the introduction of auditory steady state responses (ASSR) has enabled objective hearing tests in newborn hearing screening and automated hearing threshold assessment. The type and degree of hearing loss can be determined using the abovementioned methods...
December 8, 2017: HNO
https://www.readbyqxmd.com/read/29222566/motivation-to-address-self-reported-hearing-problems-in-adults-with-normal-hearing-thresholds
#8
Carly C M Alicea, Karen A Doherty
Purpose: The purpose of this study was to compare the motivation to change in relation to hearing problems in adults with normal hearing thresholds but who report hearing problems and that of adults with a mild-to-moderate sensorineural hearing loss. Factors related to their motivation were also assessed. Method: The motivation to change in relation to self-reported hearing problems was measured using the University of Rhode Island Change Assessment (McConnaughy, Prochaska, & Velicer, 1983)...
December 8, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29218724/genetic-disruption-of-fractalkine-signaling-leads-to-enhanced-loss-of-cochlear-afferents-following-ototoxic-or-acoustic-injury
#9
Tejbeer Kaur, Kevin K Ohlemiller, Mark E Warchol
Cochlear hair cells are vulnerable to a variety of insults like acoustic trauma and ototoxic drugs. Such injury can also lead to degeneration of spiral ganglion neurons (SGNs), but this occurs over a period of months to years. Neuronal survival is necessary for the proper function of cochlear prosthetics, therefore it is of great interest to understand the mechanisms that regulate neuronal survival in deaf ears. We have recently demonstrated that selective hair cell ablation is sufficient to attract leukocytes into the spiral ganglion (SG), and that fractalkine signaling plays a role in macrophage recruitment and in the survival of auditory neurons...
December 8, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29214174/feasibility-of-round-window-stimulation-by-a-novel-electromagnetic-microactuator
#10
Wouter Johannes van Drunen, Mathias Mueller, Anatoly Glukhovskoy, Rolf Salcher, Marc Christopher Wurz, Thomas Lenarz, Hannes Maier
Introduction: Most implantable hearing aids currently available were developed to compensate the sensorineural hearing loss by driving middle ear structures (e.g., the ossicles). These devices are successfully used in round window (RW) stimulation clinically, although this was initially not the intended use. Here, a novel microactuator, specifically designed for RW stimulation, was tested in human temporal bones to determine actuator performance and applicability. Methods: Stapes footplate response to RW stimulation was determined experimentally in human temporal bones and the obtained sound pressure output level was estimated...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29212424/surgical-complications-of-cochlear-implantation-in-a-tertiary-university-hospital
#11
Al Hussein Awad, Usama M Rashad, Nihal Gamal, Mostafa A Youssif
INTRODUCTION: Cochlear implantation remains a popular and effective therapy for patients with sensorineural hearing loss that not get benefit from conventional hearing aids Objective: To analyze the surgical complications obtained in patients that underwent cochlear implantation in a tertiary university hospital. MATERIALS AND METHODS: Retrospective analysis of the medical files of cochlear implant patients who underwent surgery at our institution between October 2014 and July 2016...
December 7, 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/29212121/erythrocyte-membrane-fluidity-alterations-in-sudden-sensorineural-hearing-loss-patients-the-role-of-oxidative-stress
#12
Matteo Becatti, Rossella Marcucci, Amanda Mannucci, Anna Maria Gori, Betti Giusti, Francesco Sofi, Lucia Mannini, Anna Paola Cellai, Agatina Alessandrello Liotta, Marco Mugnaini, Giacomo Emmi, Domenico Prisco, Niccolò Taddei, Claudia Fiorillo
No abstract text is available yet for this article.
December 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29210948/cochlear-implantation-in-a-patient-with-sickle-cell-disease-with-early-cochlear-sclerosis
#13
Seon Jeong Kim, Muhammad Reza Taheri, Marquitta Merkison, Ashkan Monfared
OBJECTIVE: We report a case of bilateral sudden sensorineural hearing loss (SNHL) and early cochlear sclerosis in a patient with sickle cell disease. METHODS: A 19-year-old female presented with sequential bilateral sudden SNHL and early cochlear sclerosis. Cochlear implantation was performed. RESULTS: Early cochlear fibrosis in the hook region and basal turn was encountered within a few months of deafness. Implantation required serial dilation using various insertion guides...
November 28, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29210944/stapes-release-in-tympanosclerosis
#14
Es-Hak Bedri, Nebiat Teferi, Miriam Redleaf
: Tympanosclerosis in the middle ear space is common in Ethiopia and often involves the ossicles and particularly the stapes. Ear operations in Ethiopia are relatively expensive in this country of limited medical resources and a low average living wage. In this setting, 2-stage operations using prostheses become prohibitively expensive. Therefore, the recommended 2-stage approach for tympanic membrane perforation with tympanosclerosis and stapes fixation is impractical for Ethiopia.We present a series of 67 patients who had a single stage tympanoplasty, removal of tympanosclerosis from the stapes suprastructure, and ossicular chain reconstruction using ossicular interposition...
November 28, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29209852/clinical-predictors-for-satisfaction-with-incus-vibroplasty-a-preliminary-study
#15
Jae Joon Han, Jihye Rhee, Jae-Jin Song, Ja-Won Koo, Byung Yoon Choi
OBJECTIVE: We aimed to evaluate the subjective satisfaction after incus vibroplasty and to determine predictive factors affecting patient satisfaction in sensorineural hearing loss. DESIGN: A retrospective review of audiological data and an additional survey about subjective satisfaction after surgery were performed in 14 patients who underwent incus vibroplasty surgery. A numeric rating scale reflecting the degree of satisfaction after incus vibroplasty, compared with experiences using a conventional hearing aid, was used...
December 5, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29207275/clinical-features-of-otolith-organ-specific-vestibular-dysfunction
#16
Chisato Fujimoto, Sayaka Suzuki, Makoto Kinoshita, Naoya Egami, Keiko Sugasawa, Shinichi Iwasaki
OBJECTIVE: To elucidate the clinical features and vestibular symptoms of patients with otolith organ dysfunction in the presence of normal function of the semicircular canals. METHODS: We reviewed the clinical records of 277 consecutive new patients with balance disorders who underwent testing of cervical and ocular vestibular evoked myogenic potentials (cVEMPs and oVEMPs) as well as caloric testing and video head impulse testing (vHIT). RESULTS: We identified 76 patients who showed normal caloric responses and normal vHIT findings in each SCC plane, but abnormal responses in cVEMP and/or oVEMP testing...
November 21, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29205794/biallelic-mutations-in-lars2-can-cause-perrault-syndrome-type-2-with-neurologic-symptoms
#17
Rika Kosaki, Reiko Horikawa, Eriko Fujii, Kenjiro Kosaki
Perrault syndrome represents a genetically heterogeneous disorder characterized by sensorineural hearing loss in males and females and ovarian dysfunction in females. Causative genes include HARS2, HSD17B4, CLPP, C10orf2, and LARS2. Some patients with Perrault syndrome exhibit neurologic features including learning disability, cerebellar ataxia, and peripheral neuropathy and are classified as type 2 and are clinically separate from those without neurological symptoms other than a hearing loss (type 1). To date, all reported patients with LARS2 mutations (15 patients in 8 families) have been classified as type 1...
December 3, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29201313/hearing-loss-in-iranian-thalassemia-major-patients-treated-with-deferoxamine-a-systematic-review-and-meta-analysis
#18
REVIEW
Gholamreza Badfar, Akram Mansouri, Masoumeh Shohani, Hamid Karimi, Zahra Khalighi, Shoboo Rahmati, Ali Delpisheh, Yousef Veisani, Ali Soleymani, Milad Azami
Background: Hearing disorders are reported in thalassemia patients treated with deferoxamine. This study aimed to assess hearing loss in Iranian thalassemia major patients treated with deferoxamine. Methods: This review article was designed based on PRISMA guidelines. To review the literature, two researchers studied national and international databases including Iranmedex, Magiran, Medlib, SID, Scopus, PubMed, Science Direct, Web of Science and Google Scholar without time limit until May 2017...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/29200406/sensorineural-hearing-loss-in-a-patient-with-swyer-syndrome
#19
Po-Jun Chen, Hsin-Chien Chen
No abstract text is available yet for this article.
January 2018: Clinical Dysmorphology
https://www.readbyqxmd.com/read/29200148/macrothrombocytopenia-with-congenital-bilateral-cataracts-a-phenotype-of-myh9-disorder-with-exon-24-indel-mutations
#20
Takahiro Aoki, Shinji Kunishima, Yoshiharu Yamashita, Kanshi Minamitani, Setsuo Ota
MYH9 disorder is characterized by large platelets and granulocyte inclusion bodies, and can be complicated with young-adult onsets of nephropathy, sensorineural hearing loss, and cataracts. Congenital cataracts in patients with MYH9 disorder is rare, and their etiology has not been elucidated. We report a 3-year-old patient with MYH9 disorder who had a p.E1066_A1072del mutation and developed cataracts congenitally. A review of the literature reveals that patients with an MYH9 exon 24 indel mutation, including p...
December 1, 2017: Journal of Pediatric Hematology/oncology
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