Jan Heil, Mark Augath, Vartan Kurtcuoglu, Joachim Hohmann, Wolf O Bechstein, Pim Olthof, Andreas A Schnitzbauer, Petra Seebeck, Marc Schiesser, Martin Schläpfer, Beatrice Beck-Schimmer, Erik Schadde
BACKGROUND: This animal study investigates the hypothesis of an immature liver growth following ALPPS (associating liver partition and portal vein ligation for staged hepatectomy) by measuring liver volume and function using gadoxetic acid avidity in magnetic resonance imaging (MRI) in models of ALPPS, major liver resection (LR) and portal vein ligation (PVL). METHODS: Wistar rats were randomly allocated to ALPPS, LR or PVL. In contrast-enhanced MRI scans with gadoxetic acid (Primovist®), liver volume and function of the right median lobe (=future liver remnant, FLR) and the deportalized lobes (DPL) were assessed until post-operative day (POD) 5...
December 21, 2023: HPB: the Official Journal of the International Hepato Pancreato Biliary Association