keyword
MENU ▼
Read by QxMD icon Read
search

gadobutrol

keyword
https://www.readbyqxmd.com/read/29780855/magnetic-resonance-imaging-and-histopathological-visualization-of-human-dural-lymphatic-vessels
#1
Seung-Kwon Ha, Govind Nair, Martina Absinta, Nicholas J Luciano, Daniel S Reich
In this protocol, we describe a method to visualize and map dural lymphatic vessels in-vivo using magnetic resonance imaging (MRI) and ex-vivo using histopathological techniques. While MRI protocols for routine imaging of meningeal lymphatics include contrast-enhanced T2-FLAIR and T1- weighted black-blood imaging, a more specific 3D mapping of the lymphatic system can be obtained by administering two distinct gadolinium-based MRI contrast agents on different days (gadofosveset and gadobutrol) and subsequently processing images acquired before and after administration of each type of contrast...
April 20, 2018: Bio-protocol
https://www.readbyqxmd.com/read/29744642/gadolinium-deposition-within-the-paediatric-brain-no-increased-intrinsic-t1-weighted-signal-intensity-within-the-dentate-nucleus-following-the-administration-of-a-minimum-of-four-doses-of-the-macrocyclic-agent-gadobutrol
#2
Jonathan R Young, Joe Qiao, Iren Orosz, Noriko Salamon, Mark A Franke, Hyun J Kim, Whitney B Pope
OBJECTIVES: To determine whether repeated administration of the macrocyclic gadolinium-based contrast agent (GBCA) gadobutrol in children is associated with T1-weighted hyperintensity within the dentate nucleus, an imaging surrogate for gadolinium deposition. METHODS: With institutional review board approval, we identified a cohort of eight patients aged 18 years or younger who underwent at least four gadobutrol-enhanced magnetic resonance imaging (MRI) examinations of the brain from 2013 to 2017...
May 9, 2018: European Radiology
https://www.readbyqxmd.com/read/29737947/accumulation-of-gadolinium-in-human-cerebrospinal-fluid-after-gadobutrol-enhanced-mr-imaging-a-prospective-observational-cohort-study
#3
Avinash K Nehra, Robert J McDonald, Amy M Bluhm, Tina M Gunderson, David L Murray, Paul J Jannetto, David F Kallmes, Laurence J Eckel, Jennifer S McDonald
Purpose To determine whether gadolinium accumulates within cerebrospinal fluid (CSF) in patients recently exposed to the macrocyclic agent gadobutrol and identify factors that may affect this accumulation. Materials and Methods In this prospective observational cohort study, gadolinium was quantified by using inductively coupled plasma mass spectrometry of CSF samples from patients who underwent gadobutrol-enhanced magnetic resonance (MR) imaging followed by lumbar puncture within 30 days (gadobutrol group) or patients who underwent lumbar puncture without history of gadolinium-enhanced MR imaging (control group)...
May 8, 2018: Radiology
https://www.readbyqxmd.com/read/29685551/the-effects-of-flip-angle-optimization-on-the-precision-and-reproducibility-of-feature-tracking-derived-strain-assessment-in-contrast-enhanced-bssfp-cine-images
#4
Daniel L R Kuetting, Andreas Feisst, Darius Dabir, Julian Luetkens, Rami Homsi, Daniel Thomas, Hans H Schild, Alois M Sprinkart
OBJECTIVES: The aim of this study was to investigate whether a flip angle adaptation, which is known to improve SNR and CNR in post contrast SSFP imaging, improves the precision and reproducibility of Feature Tracking (FT) derived strain assessments in post contrast bSSFP imaging. METHODS AND RESULTS: At 1.5T balanced SSFP midventricular short axis cine images were acquired with various flip angles (FA) before (FA = 50°) and 5 min after (FAs = 50°, 80°, 90°, 100°) injection of double dose Gadobutrol...
May 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29681604/-comparison-of-time-intensity-curve-with-gadobenatedimeglumine-and-gadobutrol-on-multiphase-contrast-enhanced-breast-mri
#5
Yu Komura, Takuma Mogi, Fuminori Shimizu, Katsuhiro Yatabe, Junkou Nedate, Hidenori Kanazawa, Akira Kawai
The purpose of this study was to compare the time-intensity curve (TIC) on multiphase contrast-enhanced breast magnetic resonance imaging (MRI) between Gadobenatedimeglumine (Gd-DTPA) and Gadobutrol. We assessed the images of 53 cases obtained from MRI that had malignant findings by pathology from October 2015 to October 2016 in our institute. Gd-DTPA and Gadobutrol were administrated in 16 and 37 cases, respectively. The TIC of the lesion was classified according to the Kuhl's method (type I: persistent pattern, type II: plateau pattern and type III: washout pattern)...
2018: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/29552267/fatal-anaphylactic-reaction-to-intravenous-gadobutrol-a-gadolinium-based-mri-contrast-agent
#6
Sabine Franckenberg, Florian Berger, Sarah Schaerli, Garyfalia Ampanozi, Michael Thali
We present the rare case of a fatal anaphylactic reaction to gadobutrol, a magnetic resonance imaging contrast agent, in a 42-year-old man. The patient underwent elective magnetic resonance imaging for diagnostic clarification of a suspicious finding in the abdomen. The patient had undergone contrast-enhanced computed tomography previously without the occurrence of any adverse effects. Adverse drug reactions in gadobutrol have a very low prevalence of 0.32%-3.5%, with serious adverse drug reactions in <0...
February 2018: Radiology case reports
https://www.readbyqxmd.com/read/29533723/dentate-nucleus-signal-intensity-decrease-on-t1-weighted-mr-images-after-switching-from-gadopentetate-dimeglumine-to-gadobutrol
#7
Ashkan Heshmatzadeh Behzadi, Zerwa Farooq, Yize Zhao, George Shih, Martin R Prince
Purpose To determine if the increased dentate nucleus signal intensity following six or more doses of a linear gadolinium-based contrast agent (GBCA) (gadopentetate dimeglumine) changes at follow-up examinations performed with a macrocyclic GBCA (gadobutrol). Materials and Methods This retrospective study included 13 patients with increased dentate nucleus signal intensity following at least six (range, 6-18) gadopentetate dimeglumine administrations who then underwent at least 12 months of follow-up imaging with multiple (range, 3-29) gadobutrol-enhanced magnetic resonance (MR) examinations...
June 2018: Radiology
https://www.readbyqxmd.com/read/29531871/development-of-a-three-dimensional-surgical-navigation-system-with-magnetic-resonance-angiography-and-a-three-dimensional-printer-for-robot-assisted-radical-prostatectomy
#8
Wataru Jomoto, Masao Tanooka, Hiroshi Doi, Keisuke Kikuchi, Chiemi Mitsuie, Yusuke Yamada, Toru Suzuki, Toshiko Yamano, Reiichi Ishikura, Noriko Kotoura, Shingo Yamamoto
We sought to develop a surgical navigation system using magnetic resonance angiography (MRA) and a three-dimensional (3D) printer for robot-assisted radical prostatectomy (RARP). Six patients with pathologically proven localized prostate cancer were prospectively enrolled in this study. Prostate magnetic resonance imaging (MRI), consisting of T2-weighted sampling perfection with application-optimized contrasts using different flip-angle evolutions (SPACE) and true fast imaging with steady-state precession (true FISP), reconstructed by volume rendering, was followed by dynamic contrast-enhanced MRA performed with a volumetric interpolated breath-hold examination (VIBE) during intravenous bolus injection of gadobutrol...
January 2, 2018: Curēus
https://www.readbyqxmd.com/read/29485341/delayed-clearance-of-cerebrospinal-fluid-tracer-from-entorhinal-cortex-in-idiopathic-normal-pressure-hydrocephalus-a-glymphatic-magnetic-resonance-imaging-study
#9
Per K Eide, Geir Ringstad
The glymphatic system plays a key role for clearance of waste solutes from the rodent brain. We recently found evidence of glymphatic circulation in the human brain when using magnetic resonance imaging (MRI) contrast agent as cerebrospinal fluid (CSF) tracer in conjunction with multiple MRI acquisitions (gMRI). The present study explored the hypothesis that reduced glymphatic clearance in entorhinal cortex (ERC) may be instrumental in idiopathic normal pressure hydrocephalus (iNPH) dementia. gMRI acquisitions were obtained over a 24-48 h time span in cognitively affected iNPH patients and non-cognitively affected patients with suspected CSF leaks...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29476216/late-gadolinium-enhancement-of-colorectal-liver-metastases-post-chemotherapy-is-associated-with-tumour-fibrosis-and-overall-survival-post-hepatectomy
#10
Helen M C Cheung, Paul J Karanicolas, Eugene Hsieh, Natalie Coburn, Tishan Maraj, Jin K Kim, Howaida Elhakim, Masoom A Haider, Calvin Law, Laurent Milot
PURPOSE: To determine whether late gadolinium MRI enhancement of colorectal liver metastases (CRCLM) post-chemotherapy is associated with tumour fibrosis and survival post-hepatectomy. MATERIALS AND METHODS: The institutional review board approved this retrospective cohort study and waived the requirement for informed consent. A cohort of 121 surgical patients who received preoperative MRI after chemotherapy between 2006-2012 was included in this study. Target tumour enhancement (TTE), defined as the mean contrast-to-noise ratio of up to two target lesions on late-phase gadobutrol-enhanced MRI, was determined by two independent raters...
February 23, 2018: European Radiology
https://www.readbyqxmd.com/read/29444157/does-radiation-therapy-increase-gadolinium-accumulation-in-the-brain-quantitative-analysis-of-t1-shortening-using-r1-relaxometry-in-glioblastoma-multiforme-patients
#11
Woo Hyeon Lim, Seung Hong Choi, Roh-Eul Yoo, Koung Mi Kang, Tae Jin Yun, Ji-Hoon Kim, Chul-Ho Sohn
OBJECTIVE: This study evaluated the possibility of accelerated gadolinium accumulation in irradiated brain parenchyma where the blood-brain barrier was weakened. METHODS: From January 2010 to June 2015, 44 patients with supratentorial glioblastoma were retrospectively identified who underwent pre- and post-radiation brain MR imaging, including R1 mapping. The mean dose of administered gadobutrol (Gadovist, Bayer, Germany) was 5.1 vials. Regions of interest (ROIs) were drawn around tumors that were located within 50-100% iso-dose lines of maximum radiation dose...
2018: PloS One
https://www.readbyqxmd.com/read/29419400/high-signal-intensity-in-the-dentate-nucleus-and-globus-pallidus-on-unenhanced-t1-weighted-mr-images-comparison-between-gadobutrol-and-linear-gadolinium-based-contrast-agents
#12
F G Moser, C T Watterson, S Weiss, M Austin, J Mirocha, R Prasad, J Wang
BACKGROUND AND PURPOSE: In view of the recent observations that gadolinium deposits in brain tissue after intravenous injection, our aim of this study was to compare signal changes in the globus pallidus and dentate nucleus on unenhanced T1-weighted MR images in patients receiving serial doses of gadobutrol, a macrocyclic gadolinium-based contrast agent, with those seen in patients receiving linear gadolinium-based contrast agents. MATERIALS AND METHODS: This was a retrospective analysis of on-site patients with brain tumors...
February 1, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29398574/comparison-of-enhancement-of-the-vestibular-perilymph-between-gadoterate-meglumine-and-gadobutrol-at-3-tesla-in-meniere-s-disease
#13
M Eliezer, G Poillon, A Gillibert, J Horion, Y Cruypeninck, E Gerardin, N Magne, A Attyé
PURPOSE: To compare the degree of enhancement of the perilymph between two macrocyclic gadolinium-based contrast agents (gadobutrol and gadoterate meglumine) in patients with Meniere's disease at 3-T magnetic resonance imaging (MRI). MATERIALS AND METHODS: The MRI examinations of 20 patients with Meniere's disease obtained 4hours after a single intravenous dose of macrocyclic gadolinium-based contrast agents were retrospectively compared. Ten patients (median age: 58...
February 1, 2018: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/29392837/highly-loaded-semipermeable-nanocapsules-for-magnetic-resonance-imaging
#14
Isabel Schlegel, Patricia Renz, Johanna Simon, Ingo Lieberwirth, Stefanie Pektor, Nicole Bausbacher, Matthias Miederer, Volker Mailänder, Rafael Muñoz-Espí, Daniel Crespy, Katharina Landfester
Magnetic resonance imaging has become an essential tool in medicine for the investigation of physiological processes. The key issues related to contrast agents, i.e., substances that are injected in the body for imaging, are the efficient enhancement of contrast, their low toxicity, and their defined biodistribution. Polyurea nanocapsules containing the gadolinium complex Gadobutrol as a contrast agent in high local concentration and high relaxivity up to 40 s-1 mmol-1 L are described. A high concentration of the contrast agent inside the nanocapsules can be ensured by increasing the crystallinity in the shell of the nanocapsules...
April 2018: Macromolecular Bioscience
https://www.readbyqxmd.com/read/29392488/novel-contrast-mixture-achieves-contrast-resolution-of-human-bladder-wall-suitable-for-t1-mapping-applications-in-interstitial-cystitis-and-beyond
#15
Pradeep Tyagi, Joseph Janicki, Chan-Hong Moon, Jonathan Kaufman, Christopher Chermansky
PURPOSE: Instillation of novel contrast mixture (NCM) was recently shown to improve the contrast resolution of rat bladder wall with high contrast-to-noise ratio (CNR). Here, the clinical safety and the feasibility of NCM-enhanced MRI to achieve artifact-free visualization of human bladder wall suitable for quantitative measurement of the magnetic resonance (MR) longitudinal relaxation time (T1) was assessed. METHODS: Six female subjects [two controls and two with Hunner-type interstitial cystitis IC and two with non-Hunner-type IC] consented for MRI at 3 T before and after instillation of NCM [4 mM gadobutrol and 5 mM ferumoxytol in 50 mL of sterile water for injection]...
March 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29319556/gadolinium-accumulation-in-the-deep-cerebellar-nuclei-and-globus-pallidus-after-exposure-to-linear-but-not-macrocyclic-gadolinium-based-contrast-agents-in-a-retrospective-pig-study-with-high-similarity-to-clinical-conditions
#16
Janina Boyken, Thomas Frenzel, Jessica Lohrke, Gregor Jost, Hubertus Pietsch
OBJECTIVE: The aim of this retrospective study was to determine the gadolinium (Gd) concentration in different brain areas in a pig cohort that received repeated administration of Gd-based contrast agents (GBCAs) at standard doses over several years, comparable with a clinical setting. MATERIAL AND METHODS: Brain tissue was collected from 13 Göttingen mini pigs that had received repeated intravenous injections of gadopentetate dimeglumine (Gd-DTPA; Magnevist) and/or gadobutrol (Gadovist)...
May 2018: Investigative Radiology
https://www.readbyqxmd.com/read/29306049/evaluation-of-lymphedema-in-upper-extremities-by-mr-lymphangiography-comparison-with-lymphoscintigraphy
#17
Jae Seok Bae, Roh-Eul Yoo, Seung Hong Choi, Seong Oh Park, Hak Chang, Minseok Suh, Gi Jeong Cheon
PURPOSE: To validate usefulness of magnetic resonance (MR) lymphangiography for evaluation of peripheral lymphedema in upper extremities by comparison with lymphoscintigraphy. MATERIALS AND METHODS: This prospective study had institutional review board approval and written informed consent was obtained from all patients. Initially, protocol of MR lymphangiography for upper extremity was established in seven healthy volunteers with 3.0T fat-saturated three-dimensional gradient-echo MR after gadobutrol injection...
January 3, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29275054/gadobutrol-and-the-end-of-the-tap-test
#18
Leonardo C Welling, Mariana S Welling, Eberval G Figueiredo
No abstract text is available yet for this article.
February 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29247585/simultaneous-acquisition-of-mr-angiography-and-diagnostic-images-of-abdomen-at-view-sharing-multiarterial-phases-and-comparing-the-effect-of-two-different-contrast-agents
#19
Yoshifumi Noda, Satoshi Goshima, Tomohiro Namimoto, Norihiro Shinkawa, Masataka Nakagawa, Kimihiro Kajita, Hiroshi Kawada, Nobuyuki Kawai, Yukichi Tanahashi, Masayuki Matsuo, Kyongtae T Bae, Toshinori Hirai, Yasuyuki Yamashita
BACKGROUND: Simultaneous acquisition of magnetic resonance angiography (MRA) and diagnostic images is challenging in contrast-enhanced upper abdominal MRI. PURPOSE: To evaluate the image quality of MRA of the abdomen acquired simultaneously with diagnostic MR images, and to compare the contrast effect, conspicuity of aortic branches, and pancreatic lesions in MRA between gadobutrol and gadoterate meglumine. STUDY TYPE: Prospective. POPULATION: Eighty-eight patients with known and suspected upper abdominal disease...
December 16, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29218620/the-impact-of-injector-based-contrast-agent-administration-in-time-resolved-mra
#20
Johannes Budjan, Ulrike I Attenberger, Stefan O Schoenberg, Hubertus Pietsch, Gregor Jost
OBJECTIVES: Time-resolved contrast-enhanced MR angiography (4D-MRA), which allows the simultaneous visualization of the vasculature and blood-flow dynamics, is widely used in clinical routine. In this study, the impact of two different contrast agent injection methods on 4D-MRA was examined in a controlled, standardized setting in an animal model. METHODS: Six anesthetized Goettingen minipigs underwent two identical 4D-MRA examinations at 1.5 T in a single session...
December 7, 2017: European Radiology
keyword
keyword
35135
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"