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https://www.readbyqxmd.com/read/28098957/the-risk-factors-for-postpartum-depression-a-population-based-study
#1
Michael E Silverman, Abraham Reichenberg, David A Savitz, Sven Cnattingius, Paul Lichtenstein, Christina M Hultman, Henrik Larsson, Sven Sandin
BACKGROUND: Postpartum depression (PPD) can result in negative personal and child developmental outcomes. Only a few large population-based studies of PPD have used clinical diagnoses of depression and no study has examined how a maternal depression history interacts with known risk factors. The objective of this study was to examine the impact of a depression history on PPD and pre- and perinatal risk factors. METHODS: A nationwide prospective cohort study of all women with live singleton births in Sweden from 1997 through 2008 was conducted...
January 18, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28098883/developmental-expression-of-toll%C3%A2-like-receptors-in-the-guinea-pig-lung
#2
Lingjie Ma, Jiali Yang, Li Yang, Juan Shi, Jing Xue, Yong Li, Xiaoming Liu
The guinea pig is a useful model for investigating infectious and non‑infectious lung diseases due to the sensitivity of its respiratory system and susceptibility to infectious agents. Toll‑like receptors (TLRs) are important components of the innate immune response and are critical for lung immune function. In the present study, the differentiation of epithelial cells in the guinea pig lung was examined during gestation by studying anatomic morphology and the major epithelial cell types using cell type‑specific markers...
January 17, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28098735/optical-coherence-tomography-angiography-of-the-fovea-in-children-born-preterm
#3
Khalil Ghasemi Falavarjani, Nicholas A Iafe, Federico G Velez, Steven D Schwartz, Srinivas R Sadda, David Sarraf, Irena Tsui
PURPOSE: To compare the foveal avascular zone (FAZ) area measured by optical coherence tomography angiography in children who had been born preterm with age-matched controls. METHODS: In this cross-sectional observational comparative case series, 43 eyes of 26 children (28 eyes of 15 former preterm infants and 15 eyes of 11 former term infants) between the ages of 4 and 12 years old were included. Optical coherence tomography angiography with a scan size of 3 × 3 was performed for all eyes...
January 16, 2017: Retina
https://www.readbyqxmd.com/read/28098724/central-macular-thickness-in-6-5-year-old-children-born-extremely-preterm-is-strongly-associated-with-gestational-age-even-when-adjusted-for-risk-factors
#4
Anna E C Molnar, Rebecka M Rosén, Maria Nilsson, Eva K B Larsson, Gerd E Holmström, Kerstin M Hellgren
PURPOSE: To assess the macular thickness in 6.5-year-old children born extremely preterm (EPT) in comparison with children born at term and to investigate risk factors associated with the macular thickness in the preterm group. METHODS: A population-based study of 6.5-year-old children born before the gestational age of 27 weeks and age-matched control subjects. Macular assessments with optical coherence tomography were performed, and the results were compared with neonatal risk factors and sex...
January 16, 2017: Retina
https://www.readbyqxmd.com/read/28098245/natural-cytotoxicity-receptor-1-in-mouse-unk-cell-maturation-and-function
#5
A M Felker, B A Croy
Early and midgestational decidua of mice genetically ablated for expression of the natural killer (NK) cell natural cytotoxicity receptor (NCR; Ncr1(Gfp/Gfp) mice) shows restricted angiogenesis and atypically small uterine (u)NK cells . We hypothesized that NCR1 inactivation disturbs maturation and angiokine production by uterine natural killer (uNK) cells. Using histological and morphometric approaches, we observed that Ncr1(Gfp/Gfp) but not control C57BL/6 (B6) implantation sites sustain immature, non-granulated uNK cells into midpregnancy...
January 18, 2017: Mucosal Immunology
https://www.readbyqxmd.com/read/28098215/epigenetic-modifications-at-dmrs-of-placental-genes-are-subjected-to-variations-in-normal-gestation-pathological-conditions-and-folate-supplementation
#6
Beenish Rahat, Aatish Mahajan, Rashmi Bagga, Abid Hamid, Jyotdeep Kaur
Invasive placentation and cancer development shares many similar molecular and epigenetic pathways. Paternally expressed, growth promoting genes (SNRPN, PEG10 and MEST) which are known to play crucial role in tumorogenesis, are not well studied during placentation. This study reports for the first time of the impact of gestational-age, pathological conditions and folic acid supplementation on dynamic nature of DNA and histone methylation present at their differentially methylated regions (DMRs). Here, we reported the association between low DNA methylation/H3K27me3 and higher expression of SNRPN, PEG10 and MEST in highly proliferating normal early gestational placenta...
January 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28097995/gestational-diabetes-your-survival-guide-to-diabetes-in-pregnancy-grant-paul-gestational-diabetes-your-survival-guide-to-diabetes-in-pregnancy-128pp-%C3%A2-9-99-sheldon-press-9781847094414-1847094414-formula-see-text
#7
(no author information available yet)
Gestational diabetes is one of the most common pregnancy complications, and this book is aimed at women who have developed the condition.
January 18, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28097848/-congenital-pulmonary-capillary-hemangiomatosis-in-a-newborn
#8
Sandra L Sposito Cavallo, Luciano A Macias Sobrino, Luifer J Marenco Altamar, Andrés F Mejía Alquichire
Pulmonary capillary hemangiomatosis is a rare entity characterized by the proliferation of capillaries into alveolar walls, interlobular septa, pleura and pulmonary interstitium, without malignant characteristics, with almost constant association with pulmonary hypertension. Until now two cases of congenital presentation have been reported in the literature. This is the third case in a newborn; he has not followed the usual pattern associated with pulmonary hypertension as occurs in most patients with this pathology; the highest incidence is among 20-40 years old...
February 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28097780/a-man-made-disease-fetal-neonatal-alloimmune-thrombocytopenia-due-to-incompatibility-between-oocyte-donor-and-gestational-mother
#9
Assaf Arie Barg, Aviya Dvir Ifrah, Tzipi Strauss, Michal J Simchen, Raoul Orvieto, Nurit Rosenberg, Gili Kenet
The incompatibility causing fetal and neonatal alloimmune thrombocytopenia (FNAIT) results from a fetus inheriting a paternal human platelet antigen (HPA), which is different from the maternal HPA. We present a unique case of FNAIT in a pregnancy involving an oocyte recipient mother with Turner syndrome. This is the first report of FNAIT in which the suggested mechanism involves antibodies produced by a gestational mother against the incompatible HPA of the oocyte donor.
January 18, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28097517/in-utero-exposure-of-hyperlipidemic-mice-to-diesel-exhaust-lack-of-effects-on-atherosclerosis-in-adult-offspring-fed-a-regular-chow-diet
#10
Jenna Harrigan, Divya Ravi, Jerry Ricks, Michael E Rosenfeld
Uterine stress is associated with an increased risk of later life metabolic diseases. In this study, we investigated the effect of diesel exhaust (DE) exposure in utero on adult susceptibility to atherosclerosis in genetically hyperlipidemic mice. Pregnant apolipoprotein E-deficient mice received either DE exposure (~250-300 μg/m(3) PM2.5 for 6 h/day, 5 days/week) or filtered air (FA) throughout gestation. Treatment effects on litter size and gender distribution were recorded. Plasma cholesterol and triglycerides were measured at 8, 12 and 16 weeks of age...
January 17, 2017: Cardiovascular Toxicology
https://www.readbyqxmd.com/read/28097444/obstetric-outcome-of-vanishing-twins-syndrome-a-systematic-review-and-meta-analysis
#11
REVIEW
Ling Sun, Ling X Jiang, Heng Z Chen
PURPOSE: Due to the high number of multiple embryo transfers into the uterus performed in assisted reproductive technology treatment (ART), the incidences of twin pregnancy and of vanishing twin syndrome (VTS) are correspondingly high. A number of studies have described the obstetric outcomes of the remaining fetus produced after the other twin had vanished compared with a singleton at the start following ART, but the results are mixed and contradictory. We performed a systematic review of the existing studies to explore the actual obstetric outcome of VTS to allow physicians to adequately advise their patients...
January 17, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28097431/placental-dapk1-and-autophagy-marker-lc3b-ii-are-dysregulated-by-tnf-%C3%AE-in-a-gestational-age-dependent-manner
#12
Andreas Prokesch, Astrid Blaschitz, Tamara Bauer, Gerit Moser, Ursula Hiden, Julianna Zadora, Ralf Dechend, Florian Herse, Martin Gauster
Autophagy, a cell-survival process responsible for degradation of protein aggregates and damaged organelles, is increasingly recognized as another mechanism essential for human placentation. A substantial body of experiments suggests inflammation and oxidative stress as the underlying stimuli for altered placental autophagy, giving rise to placenta dysfunction and pregnancy pathologies. Here, the hypothesis is tested whether or not pro-inflammatory cytokines interleukin (IL)-6 and tumor necrosis factor (TNF)-α are able to influence the expression profile of autophagy genes in human first-trimester villous placenta...
January 17, 2017: Histochemistry and Cell Biology
https://www.readbyqxmd.com/read/28096962/extra-virgin-olive-oil-in-maternal-diet-increases-osteogenic-genes-expression-but-high-amounts-have-deleterious-effects-on-bones-in-mice-offspring-at-adolescence
#13
Seyedeh Neda Mousavi, Fariba Koohdani, Mohamadreza Baghaban Eslaminejad, Pantea Izadi, Mohamadreza Eshraghian, Forough Azam Sayahpour, Leila Shafiei Neek, Farzad Shidfar
OBJECTIVES: Maternal high-fat diet has been shown to have deleterious effects on the offspring bones. However, there is no study to assess the effects of type and amount of maternal dietary oil in an isocaloric diet, with focus on extra virgin olive oil (EVOO). The objective of the current study was to test the hypothesis that type of maternal dietary oil has more effects than its amount in an isocaloric diet during gestation and lactation on bone genes expression in offspring in adolescence...
December 2016: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28096239/skin-to-skin-care-in-preterm-infants-receiving-respiratory-support-does-not-lead-to-physiological-instability
#14
Laila Lorenz, Jennifer A Dawson, Hannah Jones, Susan E Jacobs, Jeanie L Cheong, Susan M Donath, Peter G Davis, C Omar F Kamlin
OBJECTIVE: Providing skin-to-skin care (SSC) to preterm infants is standard practice in many neonatal intensive care units. There are conflicting reports on the stability of oxygen saturation (SpO2) during SSC, which may create a barrier to a wider implementation of SSC to infants receiving respiratory support. Regional cerebral oxygenation (rcO2) measured using near-infrared spectroscopy can serve as a surrogate parameter for cerebral oxygen delivery and consumption. We hypothesised that rcO2 during SSC would be similar to standard care in preterm infants receiving respiratory support...
January 17, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28095937/maternal-gestational-vitamin-d-supplementation-and-child-health-looking-to-the-future
#15
Marcos Pereira-Santos, Ana Marlúcia Oliveira
No abstract text is available yet for this article.
January 18, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28095889/evolution-of-gut-microbiota-composition-from-birth-to-24-weeks-in-the-infantmet-cohort
#16
Cian J Hill, Denise B Lynch, Kiera Murphy, Marynka Ulaszewska, Ian B Jeffery, Carol Anne O'Shea, Claire Watkins, Eugene Dempsey, Fulvio Mattivi, Kieran Touhy, R Paul Ross, C Anthony Ryan, Paul W O' Toole, Catherine Stanton
BACKGROUND: The gut is the most extensively studied niche of the human microbiome. The aim of this study was to characterise the initial gut microbiota development of a cohort of breastfed infants (n = 192) from 1 to 24 weeks of age. METHODS: V4-V5 region 16S rRNA amplicon Illumina sequencing and, in parallel, bacteriological culture. The metabolomic profile of infant urine at 4 weeks of age was also examined by LC-MS. RESULTS: Full-term (FT), spontaneous vaginally delivered (SVD) infants' microbiota remained stable at both phylum and genus levels during the 24-week period examined...
January 17, 2017: Microbiome
https://www.readbyqxmd.com/read/28095821/weighing-as-a-stand-alone-intervention-does-not-reduce-excessive-gestational-weight-gain-compared-to-routine-antenatal-care-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#17
Shanna M Fealy, Rachael M Taylor, Maralyn Foureur, John Attia, Lyn Ebert, Alessandra Bisquera, Alexis J Hure
BACKGROUND: Excessive gestational weight gain is associated with short and long-term adverse maternal and infant health outcomes, independent of pre-pregnancy body mass index. Weighing pregnant women as a stand-alone intervention during antenatal visits is suggested to reduce pregnancy weight gain. In the absence of effective interventions to reduce excessive gestational gain within the real world setting, this study aims to test if routine weighing as a stand-alone intervention can reduce total pregnancy weight gain and, in particular, excessive gestational weight gain...
January 17, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28095801/providing-lipid-based-nutrient-supplement-during-pregnancy-does-not-reduce-the-risk-of-maternal-p-falciparum-parasitaemia-and-reproductive-tract-infections-a-randomised-controlled-trial
#18
Minyanga Nkhoma, Per Ashorn, Ulla Ashorn, Kathryn G Dewey, Austrida Gondwe, John Mbotwa, Stephen Rogerson, Steve M Taylor, Kenneth Maleta
BACKGROUND: Maternal infections are associated with maternal and foetal adverse outcomes. Nutrient supplementation during pregnancy may reduce the occurrence of infections by improving maternal immunity. We aimed to investigate the impact of small-quantity lipid-based nutrient supplement (SQ-LNS) on the occurrence of Plasmodium falciparum parasitaemia during pregnancy and trichomoniasis, vaginal candidiasis and urinary tract infection (UTI) after delivery. METHODS: Pregnant Malawian women enrolled in the iLiNS-DYAD trial receiving daily supplementation with SQ-LNS, multiple micronutrients (MMN) or iron & folic acid (IFA) from <20 gestation weeks (gw) were assessed for P...
January 17, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28095461/the-impact-of-antenatal-depression-on-perinatal-outcomes-in-australian-women
#19
John Eastwood, Felix A Ogbo, Alexandra Hendry, Justine Noble, Andrew Page
BACKGROUND: In Australia, there is limited evidence on the impact of antenatal depression on perinatal outcomes. This study investigates the association between maternal depressive symptoms during pregnancy and key perinatal outcomes, including birth weight, gestational age at birth, breastfeeding indicators and postnatal depressive symptoms. METHOD: A retrospective cohort of mothers (N = 17,564) of all infants born in public health facilities within South Western Sydney Local Health District and Sydney Local Health District in 2014, in the state of New South Wales (NSW), Australia, was enumerated from routinely collected antenatal data to investigate the risk of adverse perinatal outcomes associated with maternal depressive symptoms during pregnancy...
2017: PloS One
https://www.readbyqxmd.com/read/28095379/diffusion-tensor-imaging-detects-occult-cerebellar-injury-in-severe-neonatal-hypoxic-ischemic-encephalopathy
#20
Monica E Lemmon, Matthias W Wagner, Thangamadhan Bosemani, Kathryn A Carson, Frances J Northington, Thierry A G M Huisman, Andrea Poretti
BACKGROUND: Despite the benefits of whole-body hypothermia therapy, many infants with hypoxic-ischemic encephalopathy (HIE) die or have significant long-term neurodevelopmental impairment. Prospectively identifying neonates at risk of poor outcome is essential but not straightforward. The cerebellum is not classically considered to be a brain region vulnerable to hypoxic-ischemic insults; recent literature suggests, however, that the cerebellum may be involved in neonatal HIE. In this study, we aimed to assess the microstructural integrity of cerebellar and linked supratentorial structures in neonates with HIE compared to neurologically healthy neonatal controls...
January 18, 2017: Developmental Neuroscience
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