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https://www.readbyqxmd.com/read/28442203/patterns-of-health-care-use-of-injured-adults-a-population-based-matched-cohort-study
#1
Rebecca J Mitchell, Cate M Cameron, Rod McClure
BACKGROUND: Healthcare use by traumatically injured individuals prior to and subsequent to their injury are not often explored for different types of injuries. This study aims to describe health care use 12 months preceding and 12 months following a traumatic injury by injury type and injury severity. METHOD: Hospital and mortality data from three Australian states were linked in a population-based matched cohort study. Individuals ≥18 years who had an injury-related hospital admission in 2009 were identified as the injured cohort...
April 14, 2017: Injury
https://www.readbyqxmd.com/read/28441941/effect-of-previous-utilization-and-out-of-pocket-expenditure-on-subsequent-utilization-of-a-state-led-public-private-partnership-scheme-chiranjeevi-yojana-to-promote-facility-births-in-gujarat-india
#2
Sandul Yasobant, Hemant Deepak Shewade, Kranti Suresh Vora, Kristi Sidney Annerstedt, Petros Isaakidis, Nishith B Dholakia, Dileep V Mavalankar
BACKGROUND: In Gujarat, India, a state led public private partnership scheme to promote facility birth named Chiranjeevi Yojana (CY) was implemented in 2005. Institutional birth is provided free of cost at accredited private health facilities to women from socially disadvantaged groups (eligible women). CY has contributed in increasing facility birth and providing substantially subsidized (but not totally free) birth care; however, the retention of mothers in this scheme in subsequent child birth is unknown...
April 25, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28439769/perceived-neighborhood-safety-is-associated-with-poor-sleep-health-among-gay-bisexual-and-other-men-who-have-sex-with-men-in-paris-france
#3
Dustin T Duncan, Su Hyun Park, William C Goedel, Noah T Kreski, Jace G Morganstein, H Rhodes Hambrick, Girardin Jean-Louis, Basile Chaix
Recent studies have examined sleep health among men who have sex with men (MSM), but no studies have examined associations of neighborhood characteristics and sleep health among this population. The purpose of this study was to examine associations between perceived neighborhood safety and sleep health among a sample of MSM in Paris, France. We placed broadcast advertisements on a popular smartphone application for MSM in October 2016 to recruit users in the Paris (France) metropolitan area (n = 580). Users were directed to complete a web-based survey, including previously used items measuring perceptions of neighborhood safety, validated measures of sleep health, and socio-demographics...
April 24, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28430692/lack-of-association-between-the-use-of-nerve-blockade-and-the-risk-of-postoperative-chronic-opioid-use-among-patients-undergoing-total-knee-arthroplasty-evidence-from-the-marketscan-database
#4
Eric C Sun, Brian T Bateman, Stavros G Memtsoudis, Mark D Neuman, Edward R Mariano, Laurence C Baker
BACKGROUND: Total knee arthroplasty (TKA) is associated with high rates of prolonged opioid use after surgery (10%-34%). By decreasing opioid use in the immediate postoperative period, perioperative nerve blockade has been hypothesized to decrease the risk of persistent opioid use. METHODS: Using health care utilization data, we constructed a sample of 120,080 patients undergoing TKA between 2002 and 2012 and used billing data to identify the utilization of peripheral or neuraxial blockade...
April 19, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28429137/women-s-alcohol-consumption-and-cumulative-incidence-of-live-birth-following-in-vitro-fertilization
#5
L E Dodge, S A Missmer, K L Thornton, M R Hacker
OBJECTIVE: The objective of this study was to determine the effect of alcohol consumption on outcomes among women undergoing in vitro fertilization (IVF). DESIGN: This study is a retrospective cohort study. SETTING: This study was performed in a private academically affiliated IVF center. PATIENTS: Patients included women presenting for their first IVF cycle from July 2004 through October 2012. INTERVENTION: Women completed self-administered questionnaires before their first IVF cycle, which included report of usual alcohol consumption...
April 20, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28428183/risk-and-burden-of-adverse-intrapartum-related-outcomes-associated-with-non-cephalic-and-multiple-birth-in-rural-nepal-a-prospective-cohort-study
#6
Naoko Kozuki, Joanne Katz, Subarna K Khatry, James M Tielsch, Steven C LeClerq, Luke C Mullany
OBJECTIVES: Intrapartum-related complications are the second leading cause of neonatal death worldwide. We estimate the community-level risk and burden of intrapartum-related fetal/neonatal mortality and morbidity associated with non-cephalic and multiple birth in rural Sarlahi District, Nepal. DESIGN: Community-based prospective cohort study. SETTING: Rural Sarlahi District, Nepal. PARTICIPANTS: Pregnant women residing in the study area...
April 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28427767/%C3%AE-arrestins-negatively-control-human-adrenomedullin-type-1-receptor-internalization
#7
Kenji Kuwasako, Kazuo Kitamura, Sayaka Nagata, Toshio Sekiguchi, Jiang Danfeng, Manabu Murakami, Yuichi Hattori, Johji Kato
Adrenomedullin (AM) is a potent hypotensive peptide that exerts a powerful variety of protective effects against multiorgan damage through the AM type 1 receptor (AM1 receptor), which consists of the calcitonin receptor-like receptor (CLR) and receptor activity-modifying protein 2 (RAMP2). Two β-arrestin (β-arr) isoforms, β-arr-1 and β-arr-2, play a central role in the agonist-induced internalization of many receptors for receptor resensitization. Notably, β-arr-biased agonists are now being tested in phase II clinical trials, targeting acute pain and acute heart failure...
April 17, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28420516/prenatal-diagnosis-and-molecular-cytogenetic-characterization-of%C3%A2-low-level-mosaic-trisomy-12-at-amniocentesis-associated-with%C3%A2-a%C3%A2-favorable-pregnancy-outcome
#8
Chih-Ping Chen, Chen-Ju Lin, Schu-Rern Chern, Peih-Shan Wu, Yen-Ni Chen, Shin-Wen Chen, Chen-Wen Pan, Chien-Wen Yang, Wayseen Wang
OBJECTIVE: We present prenatal diagnosis of low-level mosaic trisomy 12. CASE REPORT: A 40-year-old woman underwent amniocentesis at 18 weeks of gestation because of advanced maternal age, which revealed a karyotype of 47,XX,+12[5]/46,XX[24] consistent with 17.2% (5/29) mosaicism for trisomy 12. Repeat amniocentesis performed at 21 weeks of gestation revealed a karyotype of 47,XX,+12[4]/46,XX[6] consistent with 40% (4/10) mosaicism for trisomy 12. Interphase fluorescence in situ hybridization (FISH) on 112 uncultured amniocytes detected 23 cells with trisomy 12 consistent with 20...
April 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28418622/newborn-length-of-stay-and-risk-of-readmission
#9
Katie Harron, Ruth Gilbert, David Cromwell, Sam Oddie, Jan van der Meulen
BACKGROUND: Evidence on the association between newborn length of hospital stay (LOS) and risk of readmission is conflicting. We compared methods for modelling this relationship, by gestational age, using population-level hospital data on births in England between 2005-14. METHODS: The association between LOS and unplanned readmission within 30 days of postnatal discharge was explored using four approaches: (i) modelling hospital-level LOS and readmission rates; (ii) comparing trends over time in LOS and readmission; (iii) modelling individual LOS and adjusted risk of readmission; and (iv) instrumental variable analyses (hospital-level mean LOS and number of births on the same day)...
April 18, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28413917/is-the-families-first-home-visiting-program-effective-in-reducing-child-maltreatment-and-improving-child-development
#10
Mariette J Chartier, Marni D Brownell, Michael R Isaac, Dan Chateau, Nathan C Nickel, Alan Katz, Joykrishna Sarkar, Milton Hu, Carole Taylor
While home visiting programs are among the most widespread interventions to support at-risk families, there is a paucity of research investigating these programs under real-world conditions. The effectiveness of Families First home visiting (FFHV) was examined for decreasing rates of being in care of child welfare, decreasing hospitalizations for maltreatment-related injuries, and improving child development at school entry. Data for 4,562 children from home visiting and 5,184 comparison children were linked to deidentified administrative health, social services, and education data...
May 2017: Child Maltreatment
https://www.readbyqxmd.com/read/28412897/rates-of-cervical-cancer-screening-among-women-with-severe-mental-illness-in-the-public-health-system
#11
Monique James, Melanie Thomas, Latoya Frolov, Nicholas S Riano, Eric Vittinghoff, Dean Schillinger, John W Newcomer, Christina Mangurian
OBJECTIVE: This study aimed to determine cervical cancer screening rates among women with severe mental illness. METHODS: California Medicaid administrative records (2010-2011) for 31,308 women with severe mental illness were examined. Participants received specialty mental health services and were not dually eligible for Medicare. Poisson models assessed association between selected predictors and cervical cancer screening. RESULTS: Overall, 20...
April 17, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28406271/the-relationship-between-higher-social-trust-and-lower-late-hiv-diagnosis-and-mortality-differs-by-race-ethnicity-results-from-a-state-level-analysis
#12
Yusuf Ransome, Ashley Batson, Sandro Galea, Ichiro Kawachi, Denis Nash, Kenneth H Mayer
INTRODUCTION: Black men who have sex with men (MSM) continue to suffer a disproportionate burden of new HIV diagnoses and mortality. To better understand some of the reasons for these profound disparities, we examined whether the association between social trust and late HIV diagnosis and mortality differed by race/ethnicity, and investigated potential indirect effects of any observed differences. METHODS: We performed generalized structural equation modelling to assess main and interaction associations between trust among one's neighbours in 2009 (i...
April 6, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28406132/role-of-tolterodine-in-the-management-of-postoperative-catheter-related-bladder-discomfort-findings-in-a-nigerian-teaching-hospital
#13
K H Tijani, N O Akanmu, J O Olatosi, R W Ojewola
BACKGROUND: Patient discomfort secondary to an indwelling urethral catheter in the post operative period can be very distressing. These symptoms resemble the overactive bladder (OAB) syndrome. Muscarinic receptor blockers have been successful in the management of OAB. However, information on the use of these drugs in the management of the postoperative catheter-related bladder discomfort (CRBD) in sub-Saharan Africa is still relatively sparse. OBJECTIVE: To assess the efficacy of preoperative oral tolterodine in the management of CRBD in surgical patients in the immediate postoperative period...
April 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28400953/maternal-mortality-as-a-millennium-development-goal-of-the-united-nations-a-systematic-assessment-and-analysis-of-available-data-in-threshold-countries-using-indonesia-as-example
#14
Evelyn Reinke, Supriyatiningsih, Jörg Haier
BACKGROUND: In 2015 the proposed period ended for achieving the Millennium Development Goals (MDG) of the United Nations targeting to lower maternal mortality worldwide by ~ 75%. 99% of these cases appear in developing and threshold countries; but reports mostly rely on incomplete or unrepresentative data. Using Indonesia as example, currently available data sets for maternal mortality were systematically reviewed. METHODS: Besides analysis of international and national data resources, a systematic review was carried out according to Cochrane methodology to identify all data and assessments regarding maternal mortality...
June 2017: Journal of Global Health
https://www.readbyqxmd.com/read/28400629/biostatistics-series-module-8-assessing-risk
#15
Avijit Hazra, Nithya Gogtay
In observational studies, as well as in interventional ones, it is frequently necessary to estimate risk that is the association between an observed outcome or event and exposure to one or more factors that may be contributing to the event. Understanding incidence and prevalence are the starting point in any discussion of risk assessment. Incidence rate uses person-time as the denominator rather than a simple count. Ideally, rates and ratios estimated from samples should be presented with their corresponding 95% confidence intervals (CIs)...
March 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28400311/pregnancy-birth-and-infant-outcomes-by-maternal-fertility-status-the-massachusetts-outcomes-study-of-assisted-reproductive-technology
#16
Barbara Luke, Daksha Gopal, Howard Cabral, Judy E Stern, Hafsatou Diop
BACKGROUND: Births to subfertile women, with and without infertility treatment, have been reported to have lower birthweights and shorter gestations, even when limited to singletons. It is unknown whether these decrements are due to parental characteristics or aspects of infertility treatment. OBJECTIVE: The objective of the study was to evaluate the effect of maternal fertility status on the risk of pregnancy, birth, and infant complications. STUDY DESIGN: All singleton live births of ≥22 weeks' gestation and ≥350 g birthweight to Massachusetts resident women in 2004-2010 were linked to hospital discharge and vital records...
April 8, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28399567/mode-of-delivery-and-asthma-at-school-age-in-9-european-birth-cohorts
#17
Franca Rusconi, Daniela Zugna, Isabella Annesi-Maesano, Nour Baïz, Henrique Barros, Sofia Correia, Liesbeth Duijts, Francesco Forastiere, Hazel Inskip, Cecily C Kelleher, Pernille S Larsen, Monique Mommers, Anne-Marie Nybo Andersen, John Penders, Katharine Pike, Daniela Porta, Agnes Sonnenschein-van der Voort, Jordi Sunyer, Maties Torrent, Karien Viljoen, Martine Vrijheid, Lorenzo Richiardi, Claudia Galassi
Evidence on the association between mode of delivery and asthma at school age is inconclusive. We assessed the associations between specific modes of delivery and asthma in children from 9 European birth cohorts that enrolled participants between 1996 and 2006. Cohort-specific crude and adjusted risk ratios for asthma at ages 5-9 years were calculated using Poisson regression models and pooled. A sensitivity analysis was carried out in children born at term to reduce confounding due to perinatal factors. The study included 67,613 participants...
March 15, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28396111/mental-health-services-claims-and-adult-onset-asthma-in-ontario-canada
#18
Teresa To, Kandace Ryckman, Jingqin Zhu, Devon Williams, Laura Y Feldman, Kristian Larsen, Andrea Gershon
BACKGROUND: Living with asthma is associated with a decrease in quality of life due to reductions in activities of daily living and increased psychological stress, both of which are associated with poor mental health outcomes. OBJECTIVE: The objective of this study was to quantify the burden of mental disorders on the adult asthma population and compare the risk of mental health services claims (MHSCs) in the 1 year before and 1 year after asthma diagnosis. METHODS: Ontario residents aged 25 to 65 years with incident physician-diagnosed asthma between April 1, 2005, and March 31, 2012, were included...
April 7, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28389940/circulating-regulatory-b-cell-subsets-in-patients-with-neuromyelitis-optica-spectrum-disorders
#19
Jinming Han, Li Sun, Zhongkun Wang, Xueli Fan, Lifang Wang, Yang-Yang Song, Jie Zhu, Tao Jin
This study analyzed the populations of three different subsets of regulatory B cells (Bregs) in the peripheral blood mononuclear cells (PBMCs) of patients with neuromyelitis optica spectrum disorders (NMOSDs) and explored the relationship between the changes in these subsets of Bregs and the severity of NMOSD. A total of 22 patients with relapsed NMOSDs before treatment were recruited in our study, along with 20 age and gender-matched healthy controls, from May 2015 to March 2016. The percentages and numbers for three different subsets of Bregs including the CD19(+)CD24(hi)CD38(hi), CD19(+)CD24(hi)CD27(+), and CD19(+)CD5(+)CD1d(hi) populations were evaluated in parallel by flow cytometry...
April 7, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28389585/a-two-step-model-for-de-novo-activation-of-wuschel-during-plant-shoot-regeneration
#20
Tian-Qi Zhang, Heng Lian, Chuan-Miao Zhou, Lin Xu, Yuling Jiao, Jia-Wei Wang
Plant cells are totipotent and competent to regenerate from differentiated organs. It has been known for six decades that cytokinin-rich medium induces shoot regeneration from callus cells. However, the underlying molecular mechanism remains elusive. The homeodomain transcription factor WUSCHEL (WUS) is essential for de novo establishment of the shoot stem cell niche in Arabidopsis thaliana. We found that WUS-positive cells (WUS+) mark the shoot progenitor region during regeneration. A cytokinin-rich environment initially promotes the removal of the repressive histone mark H3K27me3 at the WUS locus in a cell-cycle-dependent manner...
April 7, 2017: Plant Cell
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