Hoda Zakaria, Pascale Kleinfinger, Laurence Lohmann, Jean-Marc Costa, Vassilis Tsatsaris, Laurent J Salomon, Jean-Marie Jouannic, Jonathan Rosenblatt, Adèle Demain, Alexandra Benachi, Laïla El Khattabi, Alexandre J Vivanti
OBJECTIVE: In singleton pregnancies, the use of cell-free DNA (cfDNA) analysis as a screening test for common fetal trisomies has spread worldwide though we still lack sufficient data for its use in triplet pregnancies. The objective of this study is to assess the performance of cfDNA testing in detecting fetal aneuploidies in triplet pregnancies as a first-tier test. METHOD: We performed a retrospective cohort study including data from pregnant women with a triplet pregnancy who underwent cfDNA testing between May 1, 2017, and January 15, 2020...
March 6, 2024: Prenatal Diagnosis