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Convergence insufficiency

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https://www.readbyqxmd.com/read/29667435/clinical-and-surgical-risk-factors-for-consecutive-exotropia
#1
Sophie Bryselbout, Veronique Promelle, Florent Pracca, Solange Milazzo
INTRODUCTION: Consecutive exotropia is one of the complications of esotropia surgery. Its prevalence is estimated at 4%-27%. The aim of this study was to identify the risk factors for consecutive exotropia in the aftermath of surgical treatment of esotropia. METHODS: Seventy-four patients examined in our strabismus consultation for a consecutive exotropia from January 2010 to June 2016 were retrospectively included. The age of onset of esotropia, the presence of amblyopia, the age of esotropia surgery and chosen procedure, the refractive errors, the anomalies of ocular motility, the age of onset of the consecutive exotropia and its angle of deviation were reported...
April 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29600186/symptomatic-accommodative-and-binocular-dysfunctions-from-the-use-of-flat-panel-displays
#2
Esteban Porcar, Juan Carlos Montalt, Álvaro M Pons, Enrique España-Gregori
AIM: To determine the presence of symptomatic accommodative and non-strabismic binocular dysfunctions (ANS BD) in a non-presbyopic population of video display unit (VDU) users with flat-panel displays. METHODS: One hundred and one VDU users, aged between 20 to 34y, initially participated in the study. This study excluded contact-lens wearers and subjects who had undergone refractive surgery or had any systemic or ocular disease. First, subjects were asked about the type and nature of eye symptoms they experienced during VDU use...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29577409/effect-of-treatment-of-symptomatic-convergence-insufficiency-on-reading-in-children-a-pilot-study
#3
Mitchell Scheiman, Christopher Chase, Eric Borsting, Gladys Lynn Mitchell, Marjean T Kulp, Susan A Cotter
BACKGROUND: To evaluate the impact of treatment of symptomatic convergence insufficiency using office-based vergence/accommodative therapy on reading skills in children. METHODS: Children (n = 44) ages nine to 17 years with symptomatic convergence insufficiency were administered the following four reading tests: Wechsler Individual Achievement Test II; Test of Word Reading Efficiency; Test of Silent Word Reading Fluency; and the Gray Oral Reading Test, at baseline and eight weeks after completion of a 16-week program of office-based vergence/accommodative therapy...
March 25, 2018: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29563889/mood-dimensions-show-distinct-within-subject-associations-with-non-exercise-activity-in-adolescents-an-ambulatory-assessment-study
#4
Elena D Koch, Heike Tost, Urs Braun, Gabriela Gan, Marco Giurgiu, Iris Reinhard, Alexander Zipf, Andreas Meyer-Lindenberg, Ulrich W Ebner-Priemer, Markus Reichert
Physical activity is known to preserve both physical and mental health. However, the physical activity levels of a large proportion of adolescents are insufficient. This is critical, since physical activity levels in youth have been shown to translate into adulthood. Whereas in adult populations, mood has been supposed to be one important psychological factor that drives physical activity in everyday life, this issue has been poorly studied in adolescent populations. Ambulatory Assessment is the state-of-the-art approach to investigate how mood and non-exercise activity fluctuate within persons in everyday life...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29558878/measuring-critical-care-providers-attitudes-about-controlled-donation-after-circulatory-death
#5
James R Rodrigue, Richard Luskin, Helen Nelson, Alexandra Glazier, Galen V Henderson, Francis L Delmonico
INTRODUCTION: Unfavorable attitudes and insufficient knowledge about donation after cardiac death among critical care providers can have important consequences for the appropriate identification of potential donors, consistent implementation of donation after cardiac death policies, and relative strength of support for this type of donation. The lack of reliable and valid assessment measures has hampered research to capture providers' attitudes. Design and Research Aims: Using stakeholder engagement and an iterative process, we developed a questionnaire to measure attitudes of donation after cardiac death in critical care providers (n = 112) and examined its psychometric properties...
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29549815/a-systematic-review-and-meta-analysis-of-the-reliability-and-validity-of-sensorimotor-measurement-instruments-in-people-with-chronic-low-back-pain
#6
REVIEW
Katja Ehrenbrusthoff, Cormac G Ryan, Christian Grüneberg, Denis J Martin
BACKGROUND: Deficits in the sensorimotor system and its peripheral and central processing of the affected body part might be a contributing factor to chronic low back pain (CLBP). Hence, sensorimotor assessment is important. Valid and reliable sensorimotor measurement instruments are needed. OBJECTIVE: To investigate the reliability and validity of sensorimotor measurement instruments for people with chronic low back pain (CLBP). DESIGN: Systematic review and meta-analysis...
March 2, 2018: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/29541278/combined-office-based-vergence-therapy-and-home-therapy-system-for-convergence-insufficiency-in-egyptian-children
#7
Tarek Nehad, Tamer Salem, Mohamed Nagy Elmohamady
Background: Convergence Insufficiency (CI) is a common binocular vision disorder characterized by exophoria more at near than at far, a receded Near Point of Convergence (NPC), and decreased Positive Fusional Vergence (PFV) at near. This disorder is often associated with several symptoms that may disturb the person's quality of life. Therefore, diagnosis and treatment of CI is a vital issue. Objectives: To compare therapeutic yield of Office Based Vision Therapy (OBVT) and combined OBVT with Home Therapy System (HTS) in patients with CI...
2018: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/29534348/screening-for-convergence-insufficiency-in-school-age-children
#8
Anne M Menjivar, Marjean T Kulp, G Lynn Mitchell, Andrew J Toole, Kathleen Reuter
BACKGROUND: Convergence insufficiency (CI) is a common binocular vision disorder which often causes symptoms when doing near work. However, the best screening test for CI is unknown. The purpose of this study was to evaluate the ability of common tests of binocular and accommodative function to identify children with CI in a school screening setting. METHODS: Children aged nine to 14 were invited to participate. Positive fusional vergences, near point of convergence (NPC), accommodative amplitude, accommodative facility, Modified Thorington, and the Convergence Insufficiency Symptom Survey were evaluated...
March 13, 2018: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29533238/macromolecular-refinement-by-model-morphing-using-non-atomic-parameterizations
#9
Kevin Cowtan, Jon Agirre
Refinement is a critical step in the determination of a model which explains the crystallographic observations and thus best accounts for the missing phase components. The scattering density is usually described in terms of atomic parameters; however, in macromolecular crystallography the resolution of the data is generally insufficient to determine the values of these parameters for individual atoms. Stereochemical and geometric restraints are used to provide additional information, but produce interrelationships between parameters which slow convergence, resulting in longer refinement times...
February 1, 2018: Acta Crystallographica. Section D, Structural Biology
https://www.readbyqxmd.com/read/29532496/fast-and-flexible-gpu-accelerated-binding-free-energy-calculations-within-the-amber-molecular-dynamics-package
#10
Daniel J Mermelstein, Charles Lin, Gard Nelson, Rachael Kretsch, J Andrew McCammon, Ross C Walker
Alchemical free energy (AFE) calculations based on molecular dynamics (MD) simulations are key tools in both improving our understanding of a wide variety of biological processes and accelerating the design and optimization of therapeutics for numerous diseases. Computing power and theory have, however, long been insufficient to enable AFE calculations to be routinely applied in early stage drug discovery. One of the major difficulties in performing AFE calculations is the length of time required for calculations to converge to an ensemble average...
March 12, 2018: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/29527588/numerical-algorithms-for-scatter-to-attenuation-reconstruction-in-pet-empirical-comparison-of-convergence-acceleration-and-the-effect-of-subsets
#11
Yannick Berker, Joel S Karp, Volkmar Schulz
The use of scattered coincidences for attenuation correction of positron emission tomography (PET) data has recently been proposed. For practical applications, convergence speeds require further improvement, yet there exists a trade-off between convergence speed and the risk of non-convergence. In this respect, a maximum-likelihood gradient-ascent (MLGA) algorithm and a two-branch back-projection (2BP), which was previously proposed, were evaluated. Methods: MLGA was combined with the Armijo step size rule; and accelerated using conjugate gradients, Nesterov's momentum method, and data subsets of different sizes...
September 2017: IEEE Transactions on Radiation and Plasma Medical Sciences
https://www.readbyqxmd.com/read/29473912/application-of-improved-5th-cubature-kalman-filter-in-initial-strapdown-inertial-navigation-system-alignment-for-large-misalignment-angles
#12
Wei Wang, Xiyuan Chen
In view of the fact the accuracy of the third-degree Cubature Kalman Filter (CKF) used for initial alignment under large misalignment angle conditions is insufficient, an improved fifth-degree CKF algorithm is proposed in this paper. In order to make full use of the innovation on filtering, the innovation covariance matrix is calculated recursively by an innovative sequence with an exponent fading factor. Then a new adaptive error covariance matrix scaling algorithm is proposed. The Singular Value Decomposition (SVD) method is used for improving the numerical stability of the fifth-degree CKF in this paper...
February 23, 2018: Sensors
https://www.readbyqxmd.com/read/29431132/longitudinal-changes-in-oculomotor-function-in-young-adults-with-mild-traumatic-brain-injury-in-sweden-an-exploratory-prospective-observational-study
#13
Giedre Matuseviciene, Jan Johansson, Marika Möller, Alison K Godbolt, Tony Pansell, Catharina Nygren Deboussard
OBJECTIVES: To assess (1) whether visual disturbances can be demonstrated with objective measures more often in patients with mild traumatic brain injury (mTBI) than in orthopaedic controls and non-injured controls, (2) whether such objectively demonstrated disturbances change over time and (3) whether self-reported visual symptoms after mTBI correlate with objectively measurable changes in visuomotor performance. DESIGN: A prospective, controlled, observational study, with assessments planned 7-10 and 75-100 days after injury...
February 3, 2018: BMJ Open
https://www.readbyqxmd.com/read/29422214/evidence-based-national-guidelines-for-the-management-of-suspected-fetal-growth-restriction-comparison-consensus-and-controversy
#14
REVIEW
Lesley M McCowan, Francesc Figueras, Ngaire H Anderson
Small for gestational age is usually defined as an infant with a birthweight <10th centile for a population or customized standard. Fetal growth restriction refers to a fetus that has failed to reach its biological growth potential because of placental dysfunction. Small-for-gestational-age babies make up 28-45% of nonanomalous stillbirths, and have a higher chance of neurodevelopmental delay, childhood and adult obesity, and metabolic disease. The majority of small-for-gestational-age babies are not recognized before birth...
February 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29394043/ligand-binding-pathways-and-conformational-transitions-of-the-hiv-protease
#15
Yinglong Miao, Yu-Ming Huang, Ross C Walker, J Andrew McCammon, Chia-En A Chang
It is important to determine the binding pathways and mechanisms of ligand molecules to target proteins in order to effectively design therapeutic drugs. Molecular dynamics (MD) is a promising computational tool that allows us to simulate protein-drug binding at an atomistic level. However, the gap between timescales of current simulations and those of many drug binding processes has limited the usage of conventional MD, which has been reflected in studies of the HIV protease. Here, we have applied a robust enhanced simulation method, Gaussian accelerated molecular dynamics (GaMD), to sample binding pathways of the XK263 ligand and associated protein conformational changes in the HIV protease...
February 2, 2018: Biochemistry
https://www.readbyqxmd.com/read/29393127/uric-acid-renal-lithiasis-new-concepts
#16
Fabiola Pazos Pérez
BACKGROUND: Uric acid (UA) stones are responsible for 5-10% of the formation of all kidney stones. Recently, an association between UA stones and insulin resistance, diabetes mellitus, and obesity has been demonstrated and so the incidence has increased. The development of UA stones is dependent on several risk factors, including genetic predisposition, geographical location, dietary indiscretion, and various metabolic characteristics. SUMMARY: UA nephrolithiasis can arise from diverse etiologies, all with distinct underlying defects converging to one or more of 3 defects of hyperuricosuria, acidic urine pH, and low urinary volume...
2018: Contributions to Nephrology
https://www.readbyqxmd.com/read/29371010/the-discrepancy-between-subjective-and-objective-measures-of-convergence-insufficiency-in-whiplash-associated-disorder-versus-control-participants
#17
Hadas Stiebel-Kalish, Amir Amitai, Michael Mimouni, Michael Bach, Tal Saban, Michelle Cahn, Liat Gantz
PURPOSE: Motor vehicle accidents (MVAs) are a pandemic associated with human suffering and a burden to national economies. Whiplash-associated disorders (WADs) after MVAs are associated commonly with disability claims, many of which are related to vision. Convergence insufficiency (CI) leads to visual disability associated with symptoms of ocular discomfort. We examined the incidence of symptoms and findings consistent with CI in a cohort of patients after MVA-related WAD compared with age-matched control participants...
January 19, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29364897/slower-saccadic-reading-in-parkinson-s-disease
#18
Naz Jehangir, Caroline Yizhu Yu, Jeehey Song, Mohammad Ali Shariati, Steven Binder, Jill Beyer, Veronica Santini, Kathleen Poston, Yaping Joyce Liao
Idiopathic Parkinson's Disease (PD) is characterized by degeneration of dopaminergic and other neurons, leading to motor and non-motor deficits. Abnormal eye movements in PD, including fixations, saccades, and convergence, are well described. However, saccadic reading, which requires serial and alternating saccades and fixations, is not well studied, despite its obvious impact on the quality of life. In this study, we assessed saccadic reading using variations of the King-Devick (KD) test, a rapid single digit number naming test, as a way to assess the ability to make serial left-to-right ocular motor movements necessary for reading...
2018: PloS One
https://www.readbyqxmd.com/read/29308964/the-reliability-and-validity-of-the-standardized-mensendieck-test-in-relation-to-disability-in-patients-with-chronic-pain
#19
Paul Keessen, Jolanda Maaskant, Bart Visser
The standardized Mensendieck test (SMT) was developed to quantify posture, movement, gait, and respiration. In the hands of an experienced therapist, the SMT is proven to be a reliable tool. It is unclear whether posture, movement, gait, and respiration are related to the degree of functional disability in patients with chronic pain. The objective of this study was to assess the reliability and convergent validity of the SMT in a heterogeneous sample of 50 patients with chronic pain. METHODS: Internal consistency was determined by Cronbach's α and interrater reliability by the intraclass correlation coefficient (ICC)...
January 8, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29288676/transcriptomic-profiles-of-post-smolt-atlantic-salmon-challenged-with-piscirickettsia-salmonis-reveal-a-strategy-to-evade-the-adaptive-immune-response-and-modify-cell-autonomous-immunity
#20
Marco Rozas-Serri, Andrea Peña, Lucerina Maldonado
Piscirickettsiosis is the main bacterial disease affecting the Chilean salmon farming industry and is responsible for high economic losses. The development of effective strategies to control piscirickettsiosis has been limited in part by insufficient knowledge of the host response. The aim of this study was to use RNA sequencing to describe the transcriptional profiles of the responses of post-smolt Atlantic salmon infected with LF-89-like or EM-90-like Piscirickettsia salmonis. Enrichment and pathway analyses of the differentially expressed genes revealed several central signatures following infection, including positive regulation of DC-SIGN and TLR5 signalling, which converged at the NF-κB level to modulate the pro-inflammatory cytokine response, particularly in the PS-EM-90-infected fish...
April 2018: Developmental and Comparative Immunology
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