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Convergence insufficiency

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https://www.readbyqxmd.com/read/28820926/treatment-of-convergence-insufficiency
#1
Marlet G Bazemore, Norman B Medow, Nils Mungan, Leonard B Nelson
No abstract text is available yet for this article.
July 1, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28812602/prenatal-development-supports-a-single-origin-of-laryngeal-echolocation-in-bats
#2
Zhe Wang, Tengteng Zhu, Huiling Xue, Na Fang, Junpeng Zhang, Libiao Zhang, Jian Pang, Emma C Teeling, Shuyi Zhang
Bat laryngeal echolocation is considered as one of the most complex and diverse modes of auditory sensory perception in animals and its evolutionary history has been the cause of many scientific controversies in the past two decades. To date, the majority of scientific evidence supports that bats (Chiroptera) are divided into two subordinal groups: Yinpterochiroptera, containing the laryngeal echolocating superfamily Rhinolophidae as sister taxa to the non-laryngeal echolocating family Pteropodidae; and Yangochiroptera, containing all other laryngeal echolocating lineages...
January 9, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28780589/development-of-brain-ventricular-system
#3
REVIEW
Vladimir Korzh
The brain ventricular system (BVS) consists of brain ventricles and channels connecting ventricles filled with cerebrospinal fluid (CSF). The disturbance of CSF flow has been linked to neurodegenerative disease including hydrocephalus, which manifests itself as an abnormal expansion of BVS. This relatively common developmental disorder has been observed in human and domesticated animals and linked to functional deficiency of various cells lineages facing BVS, including the choroid plexus or ependymal cells that generate CSF or the ciliated cells that cilia beating generates CSF flow...
August 5, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28746323/ocular-morbidity-among-children-of-government-schools-of-kathmandu-valley-a-follow-up-study
#4
R K Shrestha, G S Shrestha
INTRODUCTION: Ocular and vision defects are common among school going children. Vision disorders, especially refractive errors are the main disabilities of children and the leading cause of handicapping conditions of childhood. The present study was conducted to find out ocular morbidity among students of government schools of Kathmandu valley. METHODS: In the descriptive and cross-sectional study, 2412 students, comprising of 1114 (46.2%) males and 1298 (53.8%) females were enrolled in to the study from the five government schools of Kathmandu valley from 2012 to 2013...
April 2017: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/28713269/the-emerging-role-for-zinc-in-depression-and-psychosis
#5
REVIEW
Matthew A Petrilli, Thorsten M Kranz, Karine Kleinhaus, Peter Joe, Mara Getz, Porsha Johnson, Moses V Chao, Dolores Malaspina
Zinc participation is essential for all physiological systems, including neural functioning, where it participates in a myriad of cellular processes. Converging clinical, molecular, and genetic discoveries illuminate key roles for zinc homeostasis in association with clinical depression and psychosis which are not yet well appreciated at the clinical interface. Intracellular deficiency may arise from low circulating zinc levels due to dietary insufficiency, or impaired absorption from aging or medical conditions, including alcoholism...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28661673/scalable-electron-correlation-methods-3-efficient-and-accurate-parallel-local-coupled-cluster-with-pair-natural-orbitals-pno-lccsd
#6
Max Schwilk, Qianli Ma, Christoph Köppl, Hans-Joachim Werner
A well-parallelized local singles and doubles coupled-cluster (LCCSD) method using pair natural virtual orbitals (PNOs) is presented. The PNOs are constructed using large domains of projected atomic orbitals (PAOs) and orbital specific virtual orbitals (OSVs). We introduce a hierarchy of close, weak, and distant pairs, based on pair energies evaluated by local Møller-Plesset perturbation theory (LMP2). In contrast to most previous implementations of LCCSD methods, the close and weak pairs are not approximated by LMP2 but treated by higher-order methods...
July 19, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28643716/prevalence-of-ocular-morbidity-in-school-going-children-in-west-uttar-pradesh
#7
Veer Singh, K P S Malik, V K Malik, Kirti Jain
AIM OF THE STUDY: This study aims to evaluate the prevalence and to make a comparison between the ocular morbidity pattern in school going children of urban and rural areas of West Uttar Pradesh. MATERIALS AND METHODS: A school-based cross-sectional study design was adopted to examine children aged 5-15 years in randomly selected urban and rural schools of West Uttar Pradesh from June 2012 to August 2014. An optometrist did the vision and refraction, and a detailed ophthalmic examination was done by an ophthalmologist...
June 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28630229/observing-clonal-dynamics-across-spatiotemporal-axes-a-prelude-to-quantitative-fitness-models-for-cancer
#8
Andrew W McPherson, Fong Chun Chan, Sohrab P Shah
The ability to accurately model evolutionary dynamics in cancer would allow for prediction of progression and response to therapy. As a prelude to quantitative understanding of evolutionary dynamics, researchers must gather observations of in vivo tumor evolution. High-throughput genome sequencing now provides the means to profile the mutational content of evolving tumor clones from patient biopsies. Together with the development of models of tumor evolution, reconstructing evolutionary histories of individual tumors generates hypotheses about the dynamics of evolution that produced the observed clones...
June 19, 2017: Cold Spring Harbor Perspectives in Medicine
https://www.readbyqxmd.com/read/28609417/visually-evoked-potential-markers-of-concussion-history-in-patients-with-convergence-insufficiency
#9
Dmitri Poltavski, Paul Lederer, Laurie Kopko Cox
PURPOSE: We investigated whether differences in the pattern visual evoked potentials exist between patients with convergence insufficiency and those with convergence insufficiency and a history of concussion using stimuli designed to differentiate between magnocellular (transient) and parvocellular (sustained) neural pathways. METHODS: Sustained stimuli included 2-rev/s, 85% contrast checkerboard patterns of 1- and 2-degree check sizes, whereas transient stimuli comprised 4-rev/s, 10% contrast vertical sinusoidal gratings with column width of 0...
July 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28599912/efficacy-of-vision-therapy-in-children-with-learning-disability-and-associated-binocular-vision-anomalies
#10
Jameel Rizwana Hussaindeen, Prerana Shah, Krishna Kumar Ramani, Lalitha Ramanujan
PURPOSE: To report the frequency of binocular vision (BV) anomalies in children with specific learning disorders (SLD) and to assess the efficacy of vision therapy (VT) in children with a non-strabismic binocular vision anomaly (NSBVA). METHODS: The study was carried out at a centre for learning disability (LD). Comprehensive eye examination and binocular vision assessment was carried out for 94 children (mean (SD) age: 15 (2.2) years) diagnosed with specific learning disorder...
June 6, 2017: Journal of Optometry
https://www.readbyqxmd.com/read/28599074/beyond-epithelial-to-mesenchymal-transition-common-suppression-of-differentiation-programs-underlies-epithelial-barrier-dysfunction-in-mild-moderate-and-severe-asthma
#11
Lucas F Loffredo, Hiam Abdala-Valencia, Kishore R Anekalla, Lyda Cuervo-Pardo, Cara J Gottardi, Sergejs Berdnikovs
BACKGROUND: Epithelial barrier dysfunction is a central feature in the pathogenesis of allergic disease. Epithelial-to-mesenchymal transition (EMT) has been proposed as one mechanism afflicting barrier in asthma. However, genes and pathways involved in aberrant epithelial-mesenchymal signaling, and their relationship to asthma severity, are poorly understood. METHODS: We used unbiased gene network analysis to evaluate functional convergence in epithelial gene expression signatures across multiple public access transcriptomics datasets of human asthma, followed by text mining to evaluate functional marker relevance of discovered genes...
June 9, 2017: Allergy
https://www.readbyqxmd.com/read/28540011/effectiveness-of-vision-therapy-in-school-children-with-symptomatic-convergence-insufficiency
#12
Jung Un Jang, Jung Yun Jang, Kim Tai-Hyung, Hwang Woon Moon
PURPOSE: To determine the effectiveness of vision therapy among Korean elementary school children with convergence insufficiency. METHODS: A total of 235 elementary schoolchildren, 10.13 ± 2.45 years of age, were subjected to thorough eye examination including binocular vision testing. Of them, 32 individuals with symptomatic convergence insufficiency without strabismus, amblyopia, and ocular disease were chosen to receive vision therapy via brock string, barrel card, mirror stereoscope, prism goggles, and aperture rule for a duration of 8 weeks...
April 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28537542/malonate-degradation-in-acinetobacter-baylyi-adp1-operon-organization-and-regulation-by-mdcr
#13
Julie L Stoudenmire, Alicia L Schmidt, Melissa P Tumen-Velasquez, Kathryn T Elliott, Nicole S Laniohan, S Walker Whitley, Nickolaus R Galloway, Melesse Nune, Michael West, Cory Momany, Ellen L Neidle, Anna C Karls
Transcriptional regulators in the LysR or GntR families are typically encoded in the genomic neighbourhood of bacterial genes for malonate degradation. While these arrangements have been evaluated using bioinformatics methods, experimental studies demonstrating co-transcription of predicted operons were lacking. Here, transcriptional regulation was characterized for a cluster of mdc genes that enable a soil bacterium, Acinetobacter baylyi ADP1, to use malonate as a carbon source. Despite previous assumptions that the mdc-gene set forms one operon, our studies revealed distinct promoters in two different regions of a nine-gene cluster...
May 25, 2017: Microbiology
https://www.readbyqxmd.com/read/28537091/convergence-between-observations-and-interviews-in-clinical-diagnosis-of-reactive-attachment-disorder-and-disinhibited-social-engagement-disorder
#14
Hans Peter Giltaij, Paula Sophia Sterkenburg, Carlo Schuengel
OBJECTIVE: A comprehensive approach is needed for diagnosing disordered attachment behavior due to the multifaceted nature of attachment. Differences between various indicators can pose a challenge for deciding on the proper diagnosis. This study assessed the convergence between clinical interview assessment and observation-based clinical diagnosis, and their linkages with inadequate care. METHOD: Participating children ( N = 55) had intelligence quotients (IQs) between 50 and 85 and were referred for psychiatric consultation...
May 1, 2017: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/28511593/convergence-insufficiency-identifies-athletes-at-risk-of-prolonged-recovery-from-sport-related-concussion
#15
Kevin M DuPrey, David Webner, Adam Lyons, Crystal H Kucuk, Jeffrey T Ellis, Peter F Cronholm
BACKGROUND: Sensitive and specific screening methods are needed to identify athletes at risk of prolonged recovery after sport-related concussion (SRC). Convergence insufficiency (CI) is a common finding in concussed athletes. PURPOSE: To assess the relationship between CI and recovery after SRC at the initial office visit. STUDY DESIGN: Case-control study; Level of evidence, 3. METHODS: In this retrospective cohort study, 270 athletes (147 male, 123 female), mean ± SD age 14...
August 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28491916/orthoptic-treatment-of-convergence-insufficiency-in-parkinson-s-disease-a-case-series
#16
Hélène Kergoat, Caroline Law, Estefania Chriqui, Marie-Jeanne Kergoat, Bernard-Simon Leclerc, Michel Panisset, Ronald Postuma, Elizabeth L Irving
Introduction: This study reports a case series of orthoptic treatment (OT) for convergence insufficiency (CI) in individuals with Parkinson's disease (PD). Method: We are reporting two cases of individuals with PD who completed OT for CI. Both had a confirmed diagnosis of CI, accompanied by CI-type symptomatology. They each underwent an OT program consisting of three office-based visits and 8 weeks of home-based exercises. Treatment outcome was based on the changes measured pre- versus post-OT on the near point of convergence, positive fusional vergences, and symptomatology score...
January 2017: Gerontology & Geriatric Medicine
https://www.readbyqxmd.com/read/28475322/exploring-the-dynamics-of-propeller-loops-in-human-telomeric-dna-quadruplexes-using-atomistic-simulations
#17
Barira Islam, Petr Stadlbauer, Alejandro Gil-Ley, Guillermo Pérez-Hernández, Shozeb Haider, Stephen Neidle, Giovanni Bussi, Pavel Banas, Michal Otyepka, Jiri Sponer
We have carried out a series of extended unbiased molecular dynamics (MD) simulations (up to 10 μs long, ∼162 μs in total) complemented by replica-exchange with the collective variable tempering (RECT) approach for several human telomeric DNA G-quadruplex (GQ) topologies with TTA propeller loops. We used different AMBER DNA force-field variants and also processed simulations by Markov State Model (MSM) analysis. The slow conformational transitions in the propeller loops took place on a scale of a few μs, emphasizing the need for long simulations in studies of GQ dynamics...
June 13, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28415190/density-functional-calculations-of-transport-properties-in-the-nondegenerate-limit-and-the-role-of-electron-electron-scattering
#18
Michael P Desjarlais, Christian R Scullard, Lorin X Benedict, Heather D Whitley, Ronald Redmer
We compute electrical and thermal conductivities of hydrogen plasmas in the nondegenerate regime using Kohn-Sham density functional theory (DFT) and an application of the Kubo-Greenwood response formula, and demonstrate that for thermal conductivity, the mean-field treatment of the electron-electron (e-e) interaction therein is insufficient to reproduce the weak-coupling limit obtained by plasma kinetic theories. An explicit e-e scattering correction to the DFT is posited by appealing to Matthiessen's Rule and the results of our computations of conductivities with the quantum Lenard-Balescu (QLB) equation...
March 2017: Physical Review. E
https://www.readbyqxmd.com/read/28395878/cerebral-aneurysm-blood-flow-simulations-are-sensitive-to-basic-solver-settings
#19
Kendall D Dennis, David F Kallmes, Dan Dragomir-Daescu
Computational modeling of peri-aneurysmal hemodynamics is typically carried out with commercial software without knowledge of the sensitivity of the model to variation in input values. For three aneurysm models, we carried out a formal sensitivity analysis and optimization strategy focused on variation in timestep duration and model residual error values and their impact on hemodynamic outputs. We examined the solution sensitivity to timestep sizes of 10(-3)s, 10(-4)s, and 10(-5)s while using model residual error values of 10(-4), 10(-5), and 10(-6) using ANSYS Fluent to observe compounding errors and to optimize solver settings for computational efficiency while preserving solution accuracy...
April 3, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28368082/-comparison-of-the-wechsler-memory-scale-iii-and-the-spain-complutense-verbal-learning-test-in-acquired-brain-injury-construct-validity-and-ecological-validity
#20
P Luna-Lario, J Pena, N Ojeda
AIMS: To perform an in-depth examination of the construct validity and the ecological validity of the Wechsler Memory Scale-III (WMS-III) and the Spain-Complutense Verbal Learning Test (TAVEC). PATIENTS AND METHODS: The sample consists of 106 adults with acquired brain injury who were treated in the Area of Neuropsychology and Neuropsychiatry of the Complejo Hospitalario de Navarra and displayed memory deficit as the main sequela, measured by means of specific memory tests...
April 16, 2017: Revista de Neurologia
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