keyword
https://read.qxmd.com/read/38496873/deep-learning-based-coronary-artery-calcium-score-to-predict-coronary-artery-disease-in-type-2-diabetes-mellitus
#1
JOURNAL ARTICLE
Jingcheng Hu, Guangyu Hao, Jialiang Xu, Ximing Wang, Meng Chen
BACKGROUND: Coronary artery disease (CAD) in type 2 diabetes mellitus (T2DM) patients often presents diffuse lesions, with extensive calcification, and it is time-consuming to measure coronary artery calcium score (CACS). OBJECTIVES: To explore the predictive ability of deep learning (DL)-based CACS for obstructive CAD and hemodynamically significant CAD in T2DM. METHODS: 469 T2DM patients suspected of CAD who accepted CACS scan and coronary CT angiography between January 2013 and December 2020 were enrolled...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38494549/the-yield-of-routine-laboratory-examination-in-osteoporosis-evaluation-in-primary-care
#2
JOURNAL ARTICLE
Thomas Merlijn, Karin M A Swart, Christy Niemeijer, Henriëtte E van der Horst, Coen J Netelenbos, Petra J M Elders
UNLABELLED: This study evaluated the yield of routine laboratory examination in a large population of older women in primary care. The prevalence of laboratory abnormalities was low and the clinical consequences in follow-up were limited. There was a weak association of laboratory abnormalities with osteoporosis but no association with vertebral fractures and recent fractures. PURPOSE: Most osteoporosis guidelines advice routine laboratory examination. We have investigated the yield of laboratory examinations in facture risk evaluation of elderly women in primary care...
March 18, 2024: Osteoporosis International
https://read.qxmd.com/read/38485619/lipid-association-of-india-2023-update-on-cardiovascular-risk-assessment-and-lipid-management-in-indian-patients-consensus-statement-iv
#3
JOURNAL ARTICLE
Raman Puri, Manish Bansal, Vimal Mehta, P Barton Duell, Nathan D Wong, S S Iyengar, Dinesh Kalra, Devaki R Nair, Navin C Nanda, Jagat Narula, P Deedwania, Jamal Yusuf, Jamshed J Dalal, Sadanand Shetty, Vinod M Vijan, Rajeev Agarwala, Soumitra Kumar, Kris Vijay, Aziz Khan, Gurpreet Singh Wander, P C Manoria, S K Wangnoo, Viswanathan Mohan, Shashank R Joshi, Balbir Singh, Prafulla Kerkar, Rajesh Rajput, D Prabhakar, Abdul Hamid Zargar, Banshi Saboo, Ravi R Kasliwal, Saumitra Ray, Sandeep Bansal, M U Rabbani, Shibba Takkar Chhabra, Sarat Chandra, Neil Bardoloi, Narasaraju Kavalipati, Immaneni Sathyamurthy, Kunal Mahajan, Akshya Pradhan, N N Khanna, Rajesh Khadgawat, Preeti Gupta, Milan C Chag, Ashu Gupta, A Murugnathan, S N Narasingan, Sundeep Upadhyaya, Vinod Mittal, Rashida Patanwala Melinkeri, Madhur Yadav, M Raseed Mubarak, K K Pareek, Pradeep Kumar Dabla, Rashmi Nanda, J C Mohan
OBJECTIVE: In 2016, the Lipid Association of India (LAI) developed a cardiovascular risk assessment algorithm and defined low-density lipoprotein cholesterol (LDL-C) goals for prevention of atherosclerotic cardiovascular disease (ASCVD) in Indians. The recent refinements in the role of various risk factors and subclinical atherosclerosis in prediction of ASCVD risk necessitated updating the risk algorithm and treatment goals. METHODS: The LAI core committee held twenty-one meetings and webinars from June 2022 to July 2023 with experts across India and critically reviewed the latest evidence regarding the strategies for ASCVD risk prediction and the benefits and modalities for intensive lipid lowering...
February 8, 2024: Journal of Clinical Lipidology
https://read.qxmd.com/read/38480863/deep-learning-analysis-of-epicardial-adipose-tissue-to-predict-cardiovascular-risk-in-heavy-smokers
#4
JOURNAL ARTICLE
Borek Foldyna, Ibrahim Hadzic, Roman Zeleznik, Marcel C Langenbach, Vineet K Raghu, Thomas Mayrhofer, Michael T Lu, Hugo J W L Aerts
BACKGROUND: Heavy smokers are at increased risk for cardiovascular disease and may benefit from individualized risk quantification using routine lung cancer screening chest computed tomography. We investigated the prognostic value of deep learning-based automated epicardial adipose tissue quantification and compared it to established cardiovascular risk factors and coronary artery calcium. METHODS: We investigated the prognostic value of automated epicardial adipose tissue quantification in heavy smokers enrolled in the National Lung Screening Trial and followed for 12...
March 13, 2024: Commun Med (Lond)
https://read.qxmd.com/read/38479930/correlation-research-demonstrates-that-an-inflammatory-diet-is-a-risk-factor-for-calcium-oxalate-renal-stone-formation
#5
JOURNAL ARTICLE
Allen L Rodgers, Montserrat Arzoz-Fabregas, Josep Roca-Antonio, Maria Dolade-Botias, Nitin Shivappa, James R Hébert
BACKGROUND AND AIMS: Previous studies have demonstrated associations between the Dietary Inflammatory Index (DII®), an analytical tool which evaluates the inflammatory potential of the diet according to the pro- and anti-inflammatory properties of its components, and renal stone formation. However, these have not comprehensively addressed important parameters such as stone type, gender, DII scores in stone formers (SFs) and healthy controls (Cs) and associations of DII with urine and blood chemistries...
April 2024: Clinical Nutrition ESPEN
https://read.qxmd.com/read/38477812/osteoporosis-presenting-during-pregnancy-and-lactation-wait-and-reassess
#6
JOURNAL ARTICLE
Christopher S Kovacs
Two months after her first pregnancy, a 35-year-old exclusively breastfeeding woman bent to move her baby in the car seat and experienced sudden, severe pain from five spontaneous vertebral compression fractures. Genomic screen was negative but she had mild ankylosing spondylitis previously well controlled on Etanercept. She was vegetarian with a high phytate intake. A lactation consultant had advised her to pump and discard milk between feeds, such that she believed she produced twice as much milk as her baby ingested...
March 4, 2024: Journal of Bone and Mineral Research
https://read.qxmd.com/read/38477757/frailty-increases-the-long-term-risk-for-fall-and-fracture-related-hospitalizations-and-all-cause-mortality-in-community-dwelling-older-women
#7
JOURNAL ARTICLE
Elsa Dent, Jack Dalla Via, Trent Bozanich, Emiel O Hoogendijk, Abadi K Gebre, Cassandra Smith, Kun Zhu, Richard L Prince, Joshua R Lewis, Marc Sim
Frailty is associated with declines in physiological capacity across sensory, neurological, and musculoskeletal systems. An underlying assumption is that the frailer an individual, the more likely they are to experience falls and fractures. We examined whether grades of frailty can assess the long-term risk of hospitalized falls, fractures, and all-cause mortality in 1261 community-dwelling older women (mean age [SD] of 75.1 [2.7] yr) over 14.5 yr. Frailty was operationalized using a frailty index (FI) of cumulative deficits from 33 variables across multiple health domains (physical, mental, comorbidities) at baseline...
January 4, 2024: Journal of Bone and Mineral Research
https://read.qxmd.com/read/38477347/predictive-improvement-of-adding-coronary-calcium-score-and-a-genetic-risk-score-to-a-traditional-risk-model-for-cardiovascular-events-prediction
#8
EDITORIAL
Ian M Graham
No abstract text is available yet for this article.
March 13, 2024: European Journal of Preventive Cardiology
https://read.qxmd.com/read/38477251/biocompatibility-and-osseointegration-of-the-biomimetically-coated-and-water-soluble-eggshell-membrane-protein-cross-linked-ti-alloy-screws
#9
JOURNAL ARTICLE
Mehmet Bahadır İlik, Ercan Durmuş, İlhami Çelik
BACKGROUND: The surface properties of dental and orthopedic implants are directly related to their osseointegration rate. Coating and/or modifying the implant surface might reduce the time of healing. In this study, we aimed to examine the effects of a hybrid surface consisting of a brushite surface coating and cross-linked water-soluble eggshell membrane protein on the osseointegration of Ti screws under in vivo conditions. METHODS: Twenty Ti alloy screws were implanted monocortically in anteromedial regions of New Zealand rabbit tibiae...
October 24, 2023: Iranian Biomedical Journal
https://read.qxmd.com/read/38476649/utility-of-multimodal-longitudinal-imaging-data-for-dynamic-prediction-of-cardiovascular-and-renal-disease-the-cardia-study
#10
JOURNAL ARTICLE
Hieu Nguyen, Henrique D Vasconcellos, Kimberley Keck, Jeffrey Carr, Lenore J Launer, Eliseo Guallar, João A C Lima, Bharath Ambale-Venkatesh
BACKGROUND: Medical examinations contain repeatedly measured data from multiple visits, including imaging variables collected from different modalities. However, the utility of such data for the prediction of time-to-event is unknown, and only a fraction of the data is typically used for risk prediction. We hypothesized that multimodal longitudinal imaging data could improve dynamic disease prognosis of cardiovascular and renal disease (CVRD). METHODS: In a multi-centered cohort of 5,114 CARDIA participants, we included 166 longitudinal imaging variables from five imaging modalities: Echocardiography (Echo), Cardiac and Abdominal Computed Tomography (CT), Dual-Energy x-ray Absorptiometry (DEXA), Brain Magnetic Resonance Imaging (MRI) collected from young adulthood to mid-life over 30 years (1985-2016) to perform dynamic survival analysis of CVRD events using machine learning dynamic survival analysis (Dynamic-DeepHit, LTRCforest, and Extended Cox for Time-varying Covariates)...
2024: Front Radiol
https://read.qxmd.com/read/38474271/prefrontal-cortex-cytosolic-proteome-and-machine-learning-based-predictors-of-resilience-toward-chronic-social-isolation-in-rats
#11
JOURNAL ARTICLE
Dragana Filipović, Božidar Novak, Jinqiu Xiao, Predrag Tadić, Christoph W Turck
Chronic social isolation (CSIS) generates two stress-related phenotypes: resilience and susceptibility. However, the molecular mechanisms underlying CSIS resilience remain unclear. We identified altered proteome components and biochemical pathways and processes in the prefrontal cortex cytosolic fraction in CSIS-resilient rats compared to CSIS-susceptible and control rats using liquid chromatography coupled with tandem mass spectrometry followed by label-free quantification and STRING bioinformatics. A sucrose preference test was performed to distinguish rat phenotypes...
March 6, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38473200/the-most-important-metabolic-diseases-in-dairy-cattle-during-the-transition-period
#12
REVIEW
Vincenzo Tufarelli, Nikola Puvača, Dragan Glamočić, Gianluca Pugliese, Maria Antonietta Colonna
This review paper provides an in-depth analysis of three critical metabolic diseases affecting dairy cattle such as subacute ruminal acidosis (SARA), ketosis, and hypocalcemia. SARA represents a disorder of ruminal fermentation that is characterized by extended periods of depressed ruminal pH below 5.5-5.6. In the long term, dairy herds experiencing SARA usually exhibit secondary signs of the disease, such as episodes of laminitis, weight loss and poor body condition despite adequate energy intake, and unexplained abscesses usually 3-6 months after an episode of SARA...
March 6, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38472336/determination-of-the-combined-effects-of-asian-herbal-medicine-with-calcium-and-or-vitamin-d-supplements-on-bone-mineral-density-in-primary-osteoporosis-a-systematic-review-and-meta-analysis
#13
REVIEW
Hee-Joo Park, Min-Gyeong Kim, Young-Seo Yoo, Bo-Ram Lee, Yu-Jin Choi, Chang-Gue Son, Eun-Jung Lee
UNLABELLED: Our review of 52 RCTs from 5 databases suggests a tendency for notable improvement in BMD when combining herbal medicine with supplements (calcium and vitamin D variants) compared to supplement monotherapy in primary osteoporosis. However, caution is needed in interpreting results due to substantial heterogeneity among included studies. PURPOSE: To conduct a systematic review and meta-analysis to determine whether herbal medicine (HM) plus supplements such as calcium (Ca) or vitamin D (Vit...
March 13, 2024: Osteoporosis International
https://read.qxmd.com/read/38472025/coronary-intravascular-lithotripsy-for-severe-coronary-artery-calcification-the-disrupt-cad-i-iv-trials
#14
REVIEW
Zachary M Visinoni, Daniel L Jurewitz, Dean J Kereiakes, Richard Shlofmitz, Evan Shlofmitz, Ziad Ali, Jonathan Hill, Michael S Lee
Coronary artery calcification (CAC) severity is associated with increased vessel inflammation, atherosclerosis, stent failure, and risk of percutaneous coronary intervention-related complications. Current modalities for CAC modification include atherectomy techniques (rotational, orbital, and laser) and balloon modification (cutting and scoring). However, these methods are limited by their risk of slow flow/no reflow, coronary dissection, perforation, and myocardial infarction. Intravascular lithotripsy (IVL) emits high-energy sonic waves that induce calcium fractures within a target lesion to improve vessel compliance for stent placement...
March 3, 2024: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/38468156/association-between-red-blood-cell-distribution-width-and-coronary-calcification-in-patients-referred-for-invasive-coronary-angiography
#15
JOURNAL ARTICLE
Wen Jian, Xueqian Shen, Ze Zheng, Zheng Wu, Yuchen Shi, Jinghua Liu
This study aimed to determine whether red cell distribution width (RDW) is associated with coronary calcification. A total of 4796 patients who underwent coronary computed tomography angiography and subsequent invasive coronary angiography were consecutively enrolled. Coronary artery calcium score (CACS), demographic, clinical, and laboratory data were collected from electronic medical records. RDW were expressed in two forms, as a coefficient of variation (CV) or as a standard deviation (SD). Multivariable ordinal logistic regression was used to investigate the association of RDW with CACS grades (CACS 0-99, 100-399, 400-999, and >1000)...
March 11, 2024: Angiology
https://read.qxmd.com/read/38465913/coronary-artery-calcium-scoring-in-the-assessment-of-ascvd-risk
#16
JOURNAL ARTICLE
Edward Yang, Charles A German
No abstract text is available yet for this article.
March 11, 2024: Journal of Cardiopulmonary Rehabilitation and Prevention
https://read.qxmd.com/read/38464800/the-zero-calcium-score-paradox
#17
JOURNAL ARTICLE
Rachad Ghazal, Danish Bawa, Adnan Ahmed, Dhanunjaya Lakkireddy, Vasvi Singh
Our study presents a case of angina with a zero calcium score yet severe coronary stenosis from noncalcified plaque. We highlight the limitation of otherwise prognostically powerful coronary calcium score as a singular predictive tool especially when used in symptomatic patients.
March 6, 2024: JACC. Case reports
https://read.qxmd.com/read/38463915/mediatory-role-of-the-serum-mineral-level-and-discharge-disability-of-stroke-survivors
#18
JOURNAL ARTICLE
Soraya Khafri, Alijan Ahmadi Ahangar, Payam Saadat, Shayan Alijanpour, Mansor Babaei, Mohammadali Bayani, Alireza Firouzjahi, Farshad Fadaee Jouybari, Sepideh Hosseini Shirvani, Zahra Frajzadeh, Nafisseh Ezamie
BACKGROUND: Possible association between minerals contributing and mortality related to stroke were seen, but prospective data on the relation of vitamin D, magnesium and calcium serum levels with stroke were inconsistent. Consideration about the potential health effects of minerals and nutrients, the current study was conducted. METHODS: This analytical cross-sectional study was conducted on 216 stroke survivors who were referred to the Ayatollah Rouhani Hospital of Babol, Iran...
2024: Caspian Journal of Internal Medicine
https://read.qxmd.com/read/38463776/multivariate-analysis-and-gis-approaches-for-modeling-and-mapping-soil-quality-and-land-suitability-in-arid-zones
#19
JOURNAL ARTICLE
Mohamed E M Jalhoum, Mostafa A Abdellatif, Elsayed Said Mohamed, Dmitry E Kucher, Mohamed Shokr
Assessing soil quality marks the initial step in precision farming and agricultural management. Developing countries like Egypt face numerous hurdles in ensuring food security due to increasing populations and limited agricultural resources. A geographic information system (GIS) and multivariate analysis were utilized in the current work to evaluate and map a soil quality index (SQI). Moreover, the land suitability of the land for two plantations of the tree's oak ( Quercus robur ), and pine ( Pinus silvestris ), respectively was assessed using a parametric approach...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38463108/cardiovascular-risk-assessment-in-inflammatory-bowel-disease-with-coronary-calcium-score
#20
REVIEW
Waqar Arif Rasool Chaudhry, Muhammad Ashfaq, Parvinder Kaur, Mahendra Kumar, Maria Faraz, Jahanzeb Malik, Amin Mehmoodi
The interplay between inflammatory bowel disease (IBD) and atherosclerotic cardiovascular disease (ASCVD) underscores the intricate connections between chronic inflammation and cardiovascular health. This review explores the multifaceted relationship between these conditions, highlighting the emerging significance of the coronary calcium score as a pivotal tool in risk assessment and management. Chronic inflammation, a hallmark of IBD, has far-reaching systemic effects that extend to the cardiovascular system...
March 2024: Annals of Medicine and Surgery
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