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Ziqi Wang, Jingjing Hou, Huijuan Wang, Guowei Zhang, Zhiyong Ma
BACKGROUND: Multiple primary lung cancer (MPLC) represents a rare variety of pulmonary malignant tumor while mainly consist of double primary lung cancer (DPLC), but the development of diagnostic techniques promotes the rate diagnosis of it in recent years. Here we summarize and anylasis the data of 30 cases with DPLC in expectation of improving congnitive of MPLC. METHODS: We retrospectly studied 30 MPLC patients who diagnosed from January 2010 to December 2015 in Affiliated Cancer Hospital of Zhengzhou University...
October 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Y H Wang, F Y Huang, Y Zheng, G S Shi, L Wang, S S Liao
Objective: To examine the association between social isolation and cognitive function among the elderly living in the communities of Daqing city. Methods: A total of 981 community residents aged 60 years or over, were surveyed with a questionnaire. Both Lubben Social Network Scale-6 (LSNS-6) and Montreal Congnitive Assessment (MoCA) Changsha Versions were used to respectively screen the status of social isolation and cognitive function, on these elderly. Results: The average age was 71 years old for the 981 study participants...
April 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
Xiao Yan Zhou, Fang Zhang, Chang Jiang Ying, Jing Chen, Ling Chen, Jing Dong, Yue Shi, Mang Tang, Xiao Tong Hu, Zhi Hua Pan, Na Na Xu, Kui Yang Zheng, Ren Xian Tang, Yuan Jian Song
Diabetes mellitus often results in a number of complications involving impaired brain function, including cognitive deficits and depression. However, the potential mechanisms for diabetes-related cognitive deficits and depression are not fully understood. Neurons in the hippocampal, cortical and amygdala functional regions are more susceptible to damage during hyperglycemia. Neuroprotection in the brain can rescue cognitive deficits and depression induced by hyperglycemia. This study investigated the potential mechanisms underlying diabetes-related congnitive deficits and depression, determined whether the inflammatory factor inducible nitric oxide synthase (iNOS) and the nitric oxide (NO)/soluble guanylyl cyclases (sGC)/cyclic guanosine monophosphate (cGMP)/protein kinase G (PKG) pathway, play key roles in cognitive deficits and depression associated...
March 30, 2017: Behavioural Brain Research
Julien Caquot, Anaick Perrochon, Jean-Luc Bugeaud, Xavier Dumélié, François Duzou, Jean-Christophe Daviet
OBJECTIVE: Jumper's knee is extremely common among basketball players of high-level even in the youth categories, with adverse consequences for the continuation of the practice. To establish a preventive educational action, we have sought to examine the cognitive representations of the players concerning the patellar tendinopathy. OBJECTIVE: Raise an appraisal of presentations and ideas accepted from the basketball players participants in the championship of France hope concerning the prevention of the patellar tendinothy (PT)...
September 2016: Annals of Physical and Rehabilitation Medicine
J X Zhai, S L Tong
Polybrominated diphenyl ethers (PBDEs) was one of the most common brominated flame retardants, it has been widely used in products such as furnitures, polymer and plastical material, textiles, electronic products and building materials. PBDEs have potential effect such as neurodevelopmental toxicity, reproductive toxicity, thyroid toxicity, immunological toxicity, embryo toxicity, liver toxicity, teratogenicity and potential carcinogenicity. This paper was aimed to review the environmental exposure way, current level, neurotoxicity, neurodevelopmental toxicity and reproductive toxicity of PBDEs...
June 2016: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
Pamela L Tannenbaum, Spencer J Tye, Joanne Stevens, Anthony L Gotter, Steven V Fox, Alan T Savitz, Paul J Coleman, Jason M Uslaner, Scott D Kuduk, Richard Hargreaves, Christopher J Winrow, John J Renger
STUDY OBJECTIVES: In addition to enhancing sleep onset and maintenance, a desirable insomnia therapeutic agent would preserve healthy sleep's ability to wake and respond to salient situations while maintaining sleep during irrelevant noise. Dual orexin receptor antagonists (DORAs) promote sleep by selectively inhibiting wake-promoting neuropeptide signaling, unlike global inhibition of central nervous system excitation by gamma-aminobutyric acid (GABA)-A receptor (GABAaR) modulators. We evaluated the effect of DORA versus GABAaR modulators on underlying sleep architecture, ability to waken to emotionally relevant stimuli versus neutral auditory cues, and performance on a sleepiness-sensitive cognitive task upon awakening...
March 1, 2016: Sleep
Correne A DeCarlo, Stuart W S MacDonald, David Vergote, Jack Jhamandas, David Westaway, Roger A Dixon
OBJECTIVES: Mild cognitive impairment (MCI) is a high-risk condition for progression to Alzheimer's disease (AD). Vascular health is a key mechanism underlying age-related cognitive decline and neurodegeneration. AD-related genetic risk factors may be associated with preclinical cognitive status changes. We examine independent and cross-domain interactive effects of vascular and genetic markers for predicting MCI status and stability. METHOD: We used cross-sectional and 2-wave longitudinal data from the Victoria Longitudinal Study, including indicators of vascular health (e...
November 2016: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
Shi-ying Lv, Lan Zhang
OBJECTIVE: To examine the effect of comprehensive psychological training on the mental health of recruits and to provide basis for promoting mental health among recruits in Xinjiang. METHODS: From September to December, 2013, a convenience sampling was used to select 613 recruits from Xinjiang. These recruits were assigned to the training group (n=306) and the control group (n=307). The Simplified Coping Style Questionnaire,the Questionnaire of Armymen's Emotion Regulation Types and the Chinese Military Personnel Social Support Scale were used to evaluate the levels of mental health at the baseline and at the end of comprehensive psychological training...
April 2015: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
Yasushi Ohizumi
Alzheimer's disease (AD) has become a serious social problem in Japan. However, effective preventive and fundamental therapeutic methods for AD have not yet been developed. Using a new strategy in the course of our survey of numerous natural resouces having neurotrophic activity, we isolated a variety of active constituents and proved their pharmacological properties. As a result, we successfully found nobiletin, a compound with anti-dementia activity that comes from citrus peels. Also, we have demonstrated that nobiletin ameliorates cognitive impairment in several dementia model animals such as chronically amyloid β(Aβ) infused rats, amyloid precursor protein transgenic (APPTg) mice, olfactory-bulbectomized (OBX) mice, N-methyl-D-aspartate (NMDA) receptor antagonist (MK-801)-treated mice, senescence-accelated mice and bilaterial common carotid arteries occlusion mice...
2015: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
Qi Wang, Ming Zhang, Dian Huang, Yu Zhou, Tong Qiao
OBJECTIVE: To investigate the theraputic effects of carotid endarterectomy (CEA) on cognitive function in patients with carotid stenosis (CAS) and congnitive impairment. METHODS: CEA was performed on 38 patients with CAS from December 2011 to July 2013. There were 26 male and 12 female patients, with an average age of (70 ± 7) years. Patients was underwent neuropsychological examinations (NPEs) including Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) at 1 week before and 6 weeks after treatment...
August 2014: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
Dunja Degmecić, Tatjana Bacun, Vlatka Kovac, Josipa Mioc, Jasna Horvat, Aleksandar Vcev
Aim of the study was to determine the rate of depression and anxiety in the patients with diagnosed Type 2 Diabetes mellitus (DM), and also to determine the state of the congnitive functions in patients with Type 2 Diabetes mellitus compared with the control group. Study was designed as a epidemiological cross sectional study, sample consisted of 108 patients, 66 of the patients were diagnosed with Type 2 Diabetes mellitus, and 42 were control group. All of them were interviewed by psychiatrist and tested through clinical interview with Hamilton depression rating scale, Hamilton Anxiety rating scale, Mini mental state examination and questionnaire about sociodemografic data...
June 2014: Collegium Antropologicum
J A Michon
No abstract text is available yet for this article.
September 1992: Behavioral and Brain Sciences
Jitendra Jethani, Monika Jethani
BACKGROUND AND AIM: Children with periventricular leucomalacia (PVL) are known to have visual impairment of various forms starting from reduced vision, field defects, congnitive problems, and problems with hand eye coordination. There is very scant data/literature on the visual evoked potentials (VEPs) at an early age in children with PVL. We did a study to evaluate the flash visual evoked potentials (fVEPs) in children with PVL less than 1 year of age. MATERIALS AND METHODS: A total of nine children diagnosed as having PVL on magnetic resonance imaging were included in the study...
November 2013: Indian Journal of Ophthalmology
Mikael Sallinen
The relationship between sleep and memory and learning has proved multifilament. Besides supporting cognitive functions needed to encode, storage and retrieve materials while awake, sleep is a state during which some of the memory traces are reactivated and consolidated. Also, sleep disorders such as insomnia, obstructive sleep apnea and insufficient sleep in children and adolescents are accompanied with impairments of memory and learning as well as work and school performance. There are treatments for these disorders such as congnitive-behavioural therapy and continuous positive airway pressure, which, at least to some extent, mitigate cognitive impairments and consequently support memory and learning...
2013: Duodecim; Lääketieteellinen Aikakauskirja
Hanife Ozcelik, Cicek Fadiloglu, Bulent Karabulut, Meltem Uyar
PURPOSE: We aimed to investigate the improvement in symptoms, quality of life, patient and family satisfaction with care, and direct costs resulting from a palliative care program based case management model. METHODS: The research was implemented at the Medical Oncology Clinic hospital of a University between September 2009 and September 2011. The research sample consisted of a total of 44 patients (22 control and 22 intervention group). The research tools were the Edmonton Symptom Diagnosis System, the Karnofsky Performance Scale, the EORTCQLQ-C30 Quality of Life Scale, a patient and family satisfaction form, and a patient cost record form...
September 2014: American Journal of Hospice & Palliative Care
Chun-Xia Wang, Yuan-Zheng Sun
OBJECTIVE: To observe the effect of scalp cluster-needle intervention on cognitive ability and hippocampal vascular endothelial growth factor (VEGF) expression in cerebral ischemia (CI) rats. METHODS: Forty Wistar rats were randomized into sham operation (sham), model, scalp-acupuncture and medication groups. Chronic CI model was established by occlusion of the bilateral common carotid arteries. Acupuncture needles were inserted into "Baihui" (GV 20) and its left and right points (2 mm beside GV 20) and manipulated leftward and rightward for 3 min at a frequency of about 200 times/min, retained for 30 min...
October 2012: Zhen Ci Yan Jiu, Acupuncture Research
Suganthy Natarajan, Karutha Pandian Shunmugiah, Pandima Devi Kasi
CONTEXT: Epidemiological studies have shown that despite mortality due to communicable diseases, poverty and human conflicts, the incidence of dementia increases in the developing world in tandem with the ageing population. Although some FDA approved drugs are available for the treatment of dementia, the outcomes are often unsatisfactory. In traditional practices of medicine, numerous plants have been used to treat cognitive disorders, including neurodegenerative diseases such as Alzheimer's disease (AD) and other memory-related disorders...
April 2013: Pharmaceutical Biology
Jyoti Batra, Archana Sood
Iron deficiency evolves slowly through several stages. Early iron deficiency caused a depletion in iron stores as shown by a reduction in the levels of hepatic non-heme iron in the new born of iron deficient mothers. Of particular importance is the effect on central nervous system, which leads to the defects in the cognition and learning processes in humans. Evidence is strong that in many under developed countries iron deficiency is the main cause of anaemia and supplementation under trial conditions may prevent some defects of iron deficiency but not all...
July 2005: Indian Journal of Clinical Biochemistry: IJCB
Wei-Peng Liu, Su-Qing Qu, Zuo Luan, Xiao-Jun Gong, Zhao-Yan Wang
OBJECTIVE: To study the clinical efficacy of transplantation of human neural progenitor cells (hNPCs) in the treatment of severe cerebral palsy (CP) in children. METHODS: Forty-five children with CP were voluntarily accepted transplantation of hNPCs. The cells obtained from the forebrain of 10 to 12-week-fetus were cultured and amplified into hNPCs. Then the hNPCs were injected into the cerebral ventricle of the patients with the supersonic guidance. RESULTS: Dyssomnia, irritability and muscular tension were improved in one patient 3 days after transplantation...
October 2012: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Shu-min Yuan, Kai Gao, Dong-mei Wang, Xiong-zhi Quan, Jiang-ning Liu, Chun-mei Ma, Chuan Qin, Lian-feng Zhang
AIM: To investigate the effect of evodiamine (a quinolone alkaloid from the fruit of Evodia rutaecarpa) on the progression of Alzheimer's disease in SAMP8 and APP(swe)/PS1(ΔE9) transgenic mouse models. METHODS: The mice at age of 5 months were randomized into the model group, two evodiamine (50 mg·kg(-1)·d(-1) and 100 mg·kg(-1)·d(-1)) groups and an Aricept (2 mg·kg(-1)·d(-1)) group. The littermates of no-transgenic mice and senescence accelerated mouse/resistance 1 mice (SAMR1) were used as controls...
March 2011: Acta Pharmacologica Sinica
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