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https://www.readbyqxmd.com/read/28540206/acute-kidney-injury-from-different-poisonous-substances
#1
Rubina Naqvi
AIM: To report our experience of acute kidney injury (AKI) developed after exposure to poisonous substance. METHODS: Retrospective study where data was collected from case records of patients coming to this institute during January 1990 to May 2016. This institution is a tertiary care center for renal care in the metropolitan city of Karachi, Pakistan. History of ingested substance, symptoms on presentation, basic laboratory tests on arrival, mode of treatment and outcome were recorded from all patients and are presented here...
May 6, 2017: World Journal of Nephrology
https://www.readbyqxmd.com/read/28522363/a-bloodstream-infection-by-ruminococcus-gnavus-in-a-patient-with-a-gall-bladder-perforation
#2
Young Jin Kim, Hee Yoon Kang, Yujin Han, Mi Suk Lee, Hee Joo Lee
Ruminococcus gnavus is frequently found among human gut microbiome. However, human bloodstream infections by R. gnavus have been reported only three times. Clinical details were lacking for one case; the other two cases with concurrent bacteremia in patients with diverticulitis. We report a case of R. gnavus bloodstream infection in a patient with a gall bladder perforation suggesting its association with damage to the gastrointestinal tract. R. gnavus was misidentified using biochemical test but 16S rRNA sequencing and Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry were useful for correct identification...
May 15, 2017: Anaerobe
https://www.readbyqxmd.com/read/28511430/study-on-the-relation-between-colorectal-cancer-and-gall-bladder-disease
#3
Siddharth Gosavi, R Rama Mishra, Vsm Praveen Kumar
INTRODUCTION: Colorectal cancer is cancer of the large intestine, the lower part of digestive system which includes the sigmoid colon and rectum. AIM: To study the relation of incidence of colorectal cancer with previous gall bladder disease or post-cholecystectomy status, a relation between gall bladder disease and smoking in particular and the most common region of colon involved in colorectal cancer in gall bladder disease and non-gall bladder disease patients...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28500262/recurrent-syncope-in-systemic-lupus-erythematosus-a-hidden-cause-in-abdomen
#4
Tanvi Dev, Neetu Bhari, Priyanka Naranje, Gomathy Sethuraman
Systemic inflammatory rheumatic diseases have shown an increase in frequency of internal malignancies, predominantly lymphoproliferative disorders. Occurrence of solid organ tumours is exceedingly rare. It is even rarer for it to manifest as recurrent syncope. We report a 55-year-old woman with systemic lupus erythematosus, who later developed episodes of syncope and dizziness along with diaphoresis and palpitations. She also had associated abdominal pain and vomiting. Imaging revealed a gall bladder (GB) mass with hepatic extension, which was histologically consistent with adenocarcinoma of the GB...
May 12, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28499878/possible-role-of-organic-cation-transporters-in-the-distribution-of-11-c-sulpiride-a-dopamine-d2-receptor-antagonist
#5
Harumasa Takano, Sumito Ito, Xuan Zhang, Hiroshi Ito, Ming-Rong Zhang, Hiroshi Suzuki, Kazuya Maeda, Hiroyuki Kusuhara, Tetsuya Suhara, Yuichi Sugiyama
We synthesized [(11)C]sulpiride as a positron emission tomography (PET) probe for investigating the drug distribution in the human body. [(11)C]Sulpiride was injected to healthy male subjects in either tracer dose of [(11)C]sulpiride (ca 222 MBq) or with therapeutic dose of sulpiride (500 mg, po) 3 hours prior to the injection in a crossover fashion. Whole body PET imaging demonstrated that [(11)C]sulpiride accumulated exceedingly in the bladder, followed by liver, gall bladder and kidney respectively; at 30 minutes after the injection, whereas scarcely in the brain...
May 9, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28492356/high-frequency-irreversible-electroporation-safety-and-efficacy-of-next-generation-irreversible-electroporation-adjacent-to-critical-hepatic-structures
#6
Imran A Siddiqui, Russell C Kirks, Eduardo L Latouche, Matthew R DeWitt, Jacob H Swet, Erin H Baker, Dionisios Vrochides, David A Iannitti, Rafael V Davalos, Iain H McKillop
Irreversible electroporation (IRE) is a nonthermal ablation modality employed to induce in situ tissue-cell death. This study sought to evaluate the efficacy of a novel high-frequency IRE (H-FIRE) system to perform hepatic ablations across, or adjacent to, critical vascular and biliary structures. Using ultrasound guidance H-FIRE electrodes were placed across, or adjacent to, portal pedicels, hepatic veins, or the gall bladder in a porcine model. H-FIRE pulses were delivered (2250 V, 2-5-2 pulse configuration) in the absence of cardiac synchronization or intraoperative paralytics...
June 2017: Surgical Innovation
https://www.readbyqxmd.com/read/28480076/treatment-of-advanced-gall-bladder-cancer-in-the-real-world-can-continuation-chemotherapy-improve-outcomes
#7
Vikas Ostwal, Rakesh Pinninti, Anant Ramaswamy, Nitin Shetty, Mahesh Goel, Shraddha Patkar, Jimmy Mirani, Chaitali Nashikkar, Shripad Banavali
BACKGROUND: Gemcitabine-Platinum doublet chemotherapy is the standard of care in patients with locally advanced inoperable and metastatic (LA/M) Gall bladder cancers (GBC). METHODS: Consecutive patients with LA/M GBC treated with Gemcitabine-Cisplatin (GC) or Gemcitabine-Oxaliplatin (GO) as first line palliative chemotherapy from January 2013 to June 2015 were retrospectively analysed. Patients who were able to continue chemotherapy beyond 6-8 cycles were separately compared to those who were potential candidates for this approach, but chose not to continue chemotherapy...
April 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28480069/adjuvant-therapy-in-biliary-tract-and-gall-bladder-carcinomas-a-review
#8
REVIEW
Roshan S Prabhu, Jimmy Hwang
Biliary tract carcinomas are relatively rare, but are increasingly diagnosed. They comprise several anatomically contiguous sites, so are often grouped together, but they do appear to represent distinct diseases, in part because of anatomical and surgical considerations. Complete upfront surgical resection is generally difficult because these cancers are often diagnosed at relatively advanced stages of disease. Thus, adjuvant therapy is often considered. This paper will review the evidence underpinning current recommendations for adjuvant therapy in biliary carcinomas...
April 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28469884/peritoneo-cutaneous-fistula-from-spilled-gall-bladder-calculus-following-laparoscopic-cholecystectomy
#9
Suneed Kumar
Inadvertent spillage of gall stones is a rare yet important cause of delayed postcholecystectomy complications. Varied presentations and difficulty in diagnosis are the hallmarks, making it crucial to have a high index of suspicion to detect and intervene appropriately. Peritoneo-cutaneous fistulae from the retained stone can be completely excised in toto.
May 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28458872/isolated-dilatation-of-the-cystic-duct-type-vi-choledochal-cyst-a-rare-case-presentation-and-review-of-the-literature
#10
Samrat Ray, Bharath Kumar Bhat, Amitabh Yadav, Samiran Nundy
An isolated cystic dilatation of the cystic duct is extremely rare and very few cases have been reported in the world literature. The existing Todani's classification does not include this as a separate entity and thereby, it has been vaguely termed as a Type VI choledochal cyst by some authors in the past. We describe a case of a young male with a Type VI choledochal cyst suspected preoperatively on imaging studies and confirmed intraoperatively by laparoscopy. The cyst was localized to the cystic duct with no involvement of the common bile duct...
April 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28455439/cancer-incidence-attributable-to-excess-body-weight-in-alberta-in-2012
#11
Darren R Brenner, Abbey E Poirier, Anne Grundy, Farah Khandwala, Alison McFadden, Christine M Friedenreich
BACKGROUND: Excess body weight has been consistently associated with colorectal, breast, endometrial, esophageal, gall bladder, pancreatic and kidney cancers. The objective of this analysis was to estimate the proportion of total and site-specific cancers attributable to excess body weight in adults in Alberta in 2012. METHODS: We estimated the proportions of attributable cancers using population attributable risk. Risk estimates were obtained from recent meta-analyses, and exposure prevalence estimates were obtained from the Canadian Community Health Survey...
April 28, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28453774/effect-of-dietary-bacteriophage-supplementation-on-internal-organs-fecal-excretion-and-ileal-immune-response-in-laying-hens-challenged-by-salmonella-enteritidis
#12
P A Adhikari, D E Cosby, N A Cox, J H Lee, W K Kim
With the current researches on replacing antibiotics with different dietary interventions, bacteriophages (BP) are potential antimicrobial intervention because of their ability to affect specific bacteria. A study was conducted to evaluate the role of BP against Salmonella enterica serovar Enteritidis (SE) on SE internal organs colonization and ileum immune response in laying hens. Hens were challenged both orally and intracloacally with 108 cfu/mL cells of nalidixic acid resistant Salmonella Enteritidis (SENAR)...
April 26, 2017: Poultry Science
https://www.readbyqxmd.com/read/28450209/a-new-myxidium-species-myxozoa-myxosporea-infecting-the-gallbladder-of-the-turtle-podocnemis-unifilis-testudines-podocnemididae-from-peruvian-amazon
#13
Luis L Espinoza, Omar Mertins, Gabriella S Gama, Ana C M Fernandes Patta, Patrick D Mathews
A new myxosporean species, Myxidium peruviensis n. sp., is described parasitizing the gall bladder of the yellow-spotted river turtle Podocnemis unifilis kept in captivity in an Amazonian Peruvian turtle rescue unit in the city of Iquitos, State of Loreto, Peru. The parasite was found in four of ten (40%) P. unifilis examined. The new species was characterized based on morphological and molecular phylogeny analyses. SSU rDNA sequence of the spores of M. peruviensis n. sp. resulted in 1876 nucleotides and this sequence did no match any of the Myxozoa available in the GenBank...
April 25, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28446484/cystic-artery-pseudoaneurysm-following-acute-necrotising-pancreatitis
#14
Manoj Thillai, Pulkit Sethi, Ramachandran Narayana Menon, Nazar Puthukudiyil Kader
Cystic artery pseudoaneurysm is a rare pathology. Of the 20 cases reported so far, chronic cholecystitis and iatrogenic biliary injury form the majority of causes. Currently, there is no published report of such pseudoaneurysms caused secondary to pancreatitis, hence the management in such a scenario is unclear. We hereby present the first such report of cystic artery pseudoaneurysm occurring as a sequel of acute necrotising pancreatitis. A 33-year-old man who recovered from a recent attack of acute pancreatitis was readmitted for melena and fever...
April 26, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28425036/lobocapillaria-austropacifica-n-g-n-sp-nematoda-capillariidae-from-the-obtuse-barracuda-sphyraena-obtusata-cuvier-sphyraenidae-perciformes-off-eastern-australia
#15
František Moravec, Ian Beveridge
Based on light and scanning electron microscopical studies, a new nematode parasite, Lobocapillaria austropacifica n. sp. (Capillariidae), is described from the gall-bladder of the marine fish (obtuse barracuda) Sphyraena obtusata Cuvier (Perciformes: Sphyraenidae) from off the eastern Pacific coast of Australia, for which a new genus Lobocapillaria n. g. is established. This new genus is mainly characterised by a single row of stichocytes, the presence of two large, conspicuously elongated lateral caudal lobes and a pair of subventral papillae at their base in males, a flat spicule distended laterally towards its proximal end and provided with superficial rough transverse grooves, a spicular canal and a very long, aspinose spicular sheath with a conspicuous expansion near its proximal end when evaginated...
April 19, 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28404483/anaconda-paramyxovirus-infection-in-an-adult-green-anaconda-after-prolonged-incubation-pathological-characterization-and-whole-genome-sequence-analysis
#16
Patrick C Y Woo, Paolo Martelli, Suk-Wai Hui, Candy C Y Lau, Joseph M Groff, Rachel Y Y Fan, Susanna K P Lau, Kwok-Yung Yuen
From July 2011 to June 2012, 31 out of 33 green anaconda juveniles from an oceanarium in Hong Kong died over a 12-month period. These anacondas were progeny of a female anaconda purchased from Japan and added to the collection in May 2011. The juvenile anacondas were born in July 2011. A novel paramyxovirus, named anaconda paramyxovirus (AnaPV), was isolated from these affected juvenile anacondas. In July 2015, one of the remaining two anacondas, that survived the cluster of fatal infections, died at the age of four...
April 9, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28396555/heterotopic-pancreatic-tissue-associated-with-type-1-choledochal-cyst-cystolithiasis-and-gall-bladder-stones-a-rare-entity-with-review-of-literature
#17
Aditi Arora, Pradyumn Singh, Nidhi Anand, Nuzhat Husain
Choledochal cyst is a rare congenital malformation, particularly when associated with stones in cyst (cystolithiasis), gallstones and heterotopic pancreatic tissue within the cyst wall. The current case represents a 5-year-old boy with abdominal pain, pale colored stools, and jaundice. Magnetic resonance cholangiopancreatography showed a cystic lesion, arising from common bile duct with cystolithiasis and cholelithiasis. He underwent excision of choledochal cyst and gallbladder with Roux-en-Y hepaticojejunostomy...
April 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28365715/gall-bladder-agenesis-a-rare-embryonic-cause-of-recurrent-biliary-colic
#18
Aarthi Rajkumar, Albina Piya
BACKGROUND Gallbladder agenesis (GA) is an extremely rare anatomic anomaly with a reported incidence of less than 0.5%. It is usually asymptomatic, but can present with features of biliary colic and cholecystitis. We present here a case of GA in a patient with recurrent biliary colic.  CASE REPORT A 24-year-old African American woman presented with recurrent episodes of right upper-quadrant abdominal pain. During her first episode, she was found to have elevated transaminases and clinical features of cholecystitis, but ultrasound did not visualize a gallbladder and she was discharged with a diagnosis of biliary colic...
April 2, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28356078/calcium-oxalate-crystal-related-kidney-injury-in-a-patient-receiving-roux-en-y-hepaticojejunostomy-due-to-gall-bladder-cancer
#19
Jun-Li Tsai, Shang-Feng Tsai
BACKGROUND: Calcium oxalate nephropathy is rare in current practice. It was a common complication during jejunoileal bypass, but much less seen in modern gastric bypass surgery for morbid obesity. The major cause of it is enteric hyperoxaluria. CASE PRESENTATION: We report on a patient here with acute kidney disease due to calcium oxalate nephropathy, rather than the conditions mentioned above. The male patient received a Roux-en Y hepaticojejunostomy and common bile duct drainage...
March 29, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28355731/-the-455th-case-swollen-leg-jaundice-and-mental-disturbance
#20
R Dong, L Weng, T Guo, T N Zhu, J L Zhao, Q J Wu, X F Zeng
A 17-year-old young man with a history of swollen leg and intermittent jaundice was presented to Peking Union Medical College Hospital with acute fever and mental disturbance. He developed deep venous thrombosis, acute myocardial infarction and plantar skin necrosis during the past four years, and was presented with an acute episode of fever, thrombocytopenia, acute kidney injury, acute myocardial infarction, mental disturbance, and obstructive jaundice. Laboratory tests showed schistocytes on peripheral blood smear...
April 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
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