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Disorders of sexual development

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https://www.readbyqxmd.com/read/28210933/proposals-for-paraphilic-disorders-in-the-international-classification-of-diseases-and-related-health-problems-eleventh-revision-icd-11
#1
Richard B Krueger, Geoffrey M Reed, Michael B First, Adele Marais, Eszter Kismodi, Peer Briken
The World Health Organization is currently developing the 11th revision of the International Classifications of Diseases and Related Health Problems (ICD-11), with approval of the ICD-11 by the World Health Assembly anticipated in 2018. The Working Group on the Classification of Sexual Disorders and Sexual Health (WGSDSH) was created and charged with reviewing and making recommendations for categories related to sexuality that are contained in the chapter of Mental and Behavioural Disorders in ICD-10 (World Health Organization 1992a)...
February 16, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28208595/congenital-malformations-in-river-buffalo-bubalus-bubalis
#2
REVIEW
Sara Albarella, Francesca Ciotola, Emanuele D'Anza, Angelo Coletta, Luigi Zicarelli, Vincenzo Peretti
The world buffalo population is about 168 million, and it is still growing, in India, China, Brazil, and Italy. In these countries, buffalo genetic breeding programs have been performed for many decades. The occurrence of congenital malformations has caused a slowing of the genetic progress and economic loss for the breeders, due to the death of animals, or damage to their reproductive ability or failing of milk production. Moreover, they cause animal welfare reduction because they can imply foetal dystocia and because the affected animals have a reduced fitness with little chances of survival...
February 10, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28202904/genome-wide-dna-de-methylation-is-associated-with-noninfectious-bud-failure-exhibition-in-almond-prunus-dulcis-mill-d-a-webb
#3
Jonathan Fresnedo-Ramírez, Helen M Chan, Dan E Parfitt, Carlos H Crisosto, Thomas M Gradziel
Noninfectious bud-failure (BF) remains a major threat to almond production in California, particularly with the recent rapid expansion of acreage and as more intensive cultural practices and modern cultivars are adopted. BF has been shown to be inherited in both vegetative and sexual progeny, with exhibition related to the age and propagation history of scion clonal sources. These characteristics suggest an epigenetic influence, such as the loss of juvenility mediated by DNA-(de)methylation. Various degrees of BF have been reported among cultivars as well as within sources of clonal propagation of the same cultivar...
February 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28202323/cumulative-adverse-childhood-experiences-and-sexual-satisfaction-in-sex-therapy-patients-what-role-for-symptom-complexity
#4
Noémie Bigras, Natacha Godbout, Martine Hébert, Stéphane Sabourin
INTRODUCTION: Patients consulting for sexual difficulties frequently present additional personal or relational disorders and symptoms. This is especially the case when they have experienced cumulative adverse childhood experiences (CACEs), which are associated with symptom complexity. CACEs refer to the extent to which an individual has experienced an accumulation of different types of adverse childhood experiences including sexual, physical, and psychological abuse; neglect; exposure to inter-parental violence; and bullying...
February 12, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28195945/endurance-exercise-training-and-male-sexual-libido
#5
Anthony C Hackney, Amy R Lane, Johna Register-Mihalik, Colin B O'Leary
PURPOSE: To study the associations between aspects of endurance exercise training and the sexual libido in healthy men using a cross-sectional online survey study design. METHODS: A developed online survey questionnaire was utilized. The questionnaire was based upon pre-existing validated questionnaires and use to assess elements of physical characteristics, exercise training-habits and libido of participants (n=1077). Three evidence-based categories were created for the primary outcome of total libido score and low, normal, and high response categories set...
February 13, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28194504/variation-in-post-traumatic-response-the-role-of-trauma-type-in-predicting-icd-11-ptsd-and-cptsd-symptoms
#6
Philip Hyland, Jamie Murphy, Mark Shevlin, Frédérique Vallières, Eoin McElroy, Ask Elklit, Mogens Christoffersen, Marylène Cloitre
PURPOSE: The World Health Organization's 11th revision to the International Classification of Diseases manual (ICD-11) will differentiate between two stress-related disorders: PTSD and Complex PTSD (CPTSD). ICD-11 proposals suggest that trauma exposure which is prolonged and/or repeated, or consists of multiple forms, that also occurs under circumstances where escape from the trauma is difficult or impossible (e.g., childhood abuse) will confer greater risk for CPTSD as compared to PTSD...
February 14, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28187690/needs-of-a-silent-minority
#7
Mary Gowin, E Laurette Taylor, Jamie Dunnington, Ghadah Alshuwaiyer, Marshall K Cheney
Mexican male to female transgender asylum seekers in the United States suffer from serious health issues that can be attributed to stressors related to their transgender, ethnic minority, and socioeconomic status. This study explored these stressors, the resulting health issues, and the needs of this particularly vulnerable population. Asylum seekers' (n = 45) sworn declarations and psychological evaluations were examined by a multidisciplinary research team using a systematic document review process. The review identified stressors that occurred both in Mexico and the United States: verbal, physical, and sexual assaults; unstable environments; fear for safety/security; hiding undocumented status; and economic insecurity...
February 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28184201/long-term-high-fat-diet-treatment-an-appropriate-approach-to-study-the-sex-specificity-of-the-autonomic-and-cardiovascular-responses-to-obesity-in-mice
#8
Thiago Bruder-Nascimento, Obioma J Ekeledo, Ruchi Anderson, Huy B Le, Eric J Belin de Chantemèle
Obesity-related cardiovascular disease (CVD) involves increased sympathetic activity in men and male animals. Although women exhibit increased visceral fat, metabolic disorders, inflammation and CVD with obesity, whether body weight gain affects autonomic control of cardiovascular function in females remain unknown. Due to the lack of adequate model to mimic the human pathology, this study aimed to develop a murine model, which would allow studying the sex-specificity of the response of the autonomic nervous system to obesity and identifying the origin of potential sex-differences...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28179814/prenatal-stress-immune-programming-of-sex-differences-in-comorbidity-of-depression-and-obesity-metabolic-syndrome
#9
Jill M Goldstein, Laura Holsen, Grace Huang, Bradley D Hammond, Tamarra James-Todd, Sara Cherkerzian, Taben M Hale, Robert J Handa
Major depressive disorder (MDD) is the number one cause of disability worldwide and is comorbid with many chronic diseases, including obesity/metabolic syndrome (MetS). Women have twice as much risk for MDD and comorbidity with obesity/MetS as men, although pathways for understanding this association remain unclear. On the basis of clinical and preclinical studies, we argue that prenatal maternal stress (ie, excess glucocorticoid expression and associated immune responses) that occurs during the sexual differentiation of the fetal brain has sex-dependent effects on brain development within highly sexually dimorphic regions that regulate mood, stress, metabolic function, the autonomic nervous system, and the vasculature...
December 2016: Dialogues in Clinical Neuroscience
https://www.readbyqxmd.com/read/28179808/sex-differences-in-the-developing-brain-as-a-source-of-inherent-risk
#10
Margaret M McCarthy
Brain development diverges in males and females in response to androgen production by the fetal testis. This sexual differentiation of the brain occurs during a sensitive window and induces enduring neuroanatomical and physiological changes that profoundly impact behavior. What we know about the contribution of sex chromosomes is still emerging, highlighting the need to integrate multiple factors into understanding sex differences, including the importance of context. The cellular mechanisms are best modeled in rodents and have provided both unifying principles and surprising specifics...
December 2016: Dialogues in Clinical Neuroscience
https://www.readbyqxmd.com/read/28161615/what-do-spanish-adolescents-think-about-obsessive-compulsive-disorder-mental-health-literacy-and-stigma-associated-with-symmetry-order-and-aggression-related-symptoms
#11
Gemma García-Soriano, María Roncero
Obsessive-compulsive disorder (OCD) is a frequent and disabling disorder with a long delay in seeking help that could partly be due to poor mental health literacy and stigmatizing attitudes. This study analyzes the mental health literacy and stigma associated with symmetry/order and aggression-related OCD in a Spanish adolescent sample. This age group was chosen because adolescence is a vulnerable period for the development of OCD, and adolescents are often reluctant to seek professional help. One hundred and two non-clinical adolescents read two vignettes describing symmetry/order and aggression-related OCD...
January 31, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28152641/a-review-of-paediatric-and-adolescent-gynaecology-services-in-a-tertiary-outpatient-clinic
#12
Mugdha Kulkarni, Julie Glanville, Sally Phillot, Adam Balen
Adolescence is a distinctive stage in human development during which many simple and complex medical conditions can present for the first time. Paediatric and adolescent gynaecological conditions need careful multidisciplinary clinical management with a sensitive approach understanding the patients' psychological and physiological circumstances. The objective of this study is to review the tertiary paediatric and adolescent gynaecology service in Leeds, United Kingdom and to present an overview of the various conditions that present to such a clinic...
February 2, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28149309/deferring-surgical-treatment-of-ambiguous-genitalia-into-adolescence-in-girls-with-21-hydroxylase-deficiency-a-feasibility-study
#13
Pierre Bougnères, Claire Bouvattier, Maryse Cartigny, Lina Michala
BACKGROUND: Genital surgery in Disorders of Sex Development (DSD) has been an area of debate over the past 20 years. Emerging scientific evidence in the late 1990s defied the then routine practice to surgically align genitalia to the sex of rearing, as early as possible. However, despite multitude of data showing detrimental effects to genital sensation and sexuality, few patients born with ambiguous genitalia have remained unoperated into adolescence. METHODS: We followed up girls with 21 hydroxylase deficiency (21- OHD) in genital morphology during childhood and acceptability among patients and parents of such an approach...
2017: International Journal of Pediatric Endocrinology
https://www.readbyqxmd.com/read/28145794/the-effect-of-adverse-childhood-experience-on-clinical-diagnosis-of-a-substance-use-disorder-results-of-a-nationally-representative-study
#14
McKenzie Lynn LeTendre, Mark B Reed
BACKGROUND: Substance abuse is one of the most common health outcomes associated with adverse childhood experience, and poses a significant public health threat. OBJECTIVES: The purpose of this study is to demonstrate a relationship between adverse childhood experience and a substance use disorder using nationally representative data as well as to test whether religion moderates this relationship. METHODS: We conducted a secondary analysis using data from the National Longitudinal Study of Adolescent to Adult Health (n = 11,279)...
February 1, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28142338/toxicity-assessment-of-molindone-hydrochloride-a-dopamine-d2-d5-receptor-antagonist-in-juvenile-and-adult-rats
#15
Gopala Krishna, Gopa Gopalakrishnan, Saryu Goel
Neuroleptic drug molindone hydrochloride is a dopamine D2/D5 receptor antagonist and it is in late stage development for the treatment of impulsive aggression in children and adolescents who have attention deficient/hyperactivity disorder (ADHD). This new indication for this drug would expand the target population to include younger patients, and therefore, toxicity assessments in juvenile animals were undertaken in order to determine susceptibility differences, if any, between this age group and the adult rats...
January 31, 2017: Toxicology Mechanisms and Methods
https://www.readbyqxmd.com/read/28135599/impact-of-military-trauma-exposures-on-posttraumatic-stress-and-depression-in-female-veterans
#16
Lizabeth A Goldstein, Julie Dinh, Rosemary Donalson, Claire L Hebenstreit, Shira Maguen
Previous research has demonstrated the deleterious effects of traumatic military experiences on symptoms of posttraumatic stress disorder (PTSD) and depression in female veterans. However, more research is needed to identify the unique predictors of distressing psychological symptoms when both combat-related and sexual trauma are considered, particularly as women's combat exposure in the military increases. Female veterans who had attended at least one appointment at a large Veterans Health Administration medical center were invited to complete questionnaires about traumatic military exposures and psychiatric symptoms...
January 4, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28133513/effect-of-vitamin-d3-on-biosynthesis-of-estrogen-in-porcine-granulosa-cells-via-modulation-of-steroidogenic-enzymes
#17
So-Hye Hong, Jae-Eon Lee, Sung-Min An, Ye Young Shin, Dae Youn Hwang, Seung Yun Yang, Seong-Keun Cho, Beum-Soo An
Vitamin D3 is a fat-soluble secosteroid responsible for enhancing intestinal absorption of calcium, iron, and other materials. Vitamin D3 deficiency, therefore, can cause health problems such as metabolic diseases, and bone disorder. Female sex hormones including estrogen and progesterone are biosynthesized mainly in the granulosa cells of ovary. In this study, we isolated granulosa cells from porcine ovary and cultured for the experiments. In order to examine the effect of vitamin D3 on the ovarian granulosa cells, the mRNA and protein levels of genes were analyzed by real-time PCR and Western blot assay...
January 2017: Toxicological Research
https://www.readbyqxmd.com/read/28132705/the-juvenile-justice-behavioral-health-services-cascade-a-new-framework-for-measuring-unmet-substance-use-treatment-services-needs-among-adolescent-offenders
#18
Steven Belenko, Danica Knight, Gail A Wasserman, Michael L Dennis, Tisha Wiley, Faye S Taxman, Carrie Oser, Richard Dembo, Angela A Robertson, Jessica Sales
OVERVIEW: Substance use and substance use disorders are highly prevalent among youth under juvenile justice (JJ) supervision, and related to delinquency, psychopathology, social problems, risky sex and sexually transmitted infections, and health problems. However, numerous gaps exist in the identification of behavioral health (BH) problems and in the subsequent referral, initiation and retention in treatment for youth in community justice settings. This reflects both organizational and systems factors, including coordination between justice and BH agencies...
March 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28120258/psychopathology-subgroups-and-hiv-risk-among-women-in-psychiatric-treatment
#19
Robert C McMahon, John M Abbamonte, Jessy G Dévieux
Among individuals with mental illness, the HIV infection rate is generally found to be substantially higher than in the general population. Understanding dimensions or subtypes of psychopathology linked with HIV risk behavior may enable development of targeted interventions to reduce HIV transmission. This study identified subgroups of women (n = 243) receiving outpatient psychiatric treatment based upon cluster analysis of indices of personality disorder and clinical symptom syndromes. High, medium, and low psychiatric severity cluster subgroups were found to differ significantly on key HIV risk variables...
January 24, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28114775/risk-factors-for-ptsd-and-depression-in-female-survivors-of-rape
#20
Nolwandle Mbalo, Muyu Zhang, Sam Ntuli
Temporarily Unavailable (PsycINFO Database Record
January 23, 2017: Psychological Trauma: Theory, Research, Practice and Policy
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