keyword
https://read.qxmd.com/read/38575920/association-between-symptoms-of-depression-and-inflammatory-parameters-in-people-aged-over-90-years
#21
JOURNAL ARTICLE
Paulina Zabielska, Małgorzata Szkup, Artur Kotwas, Karolina Skonieczna-Żydecka, Beata Karakiewicz
BACKGROUND: Old age is a period of life that presents many health and social challenges, resulting in a greater vulnerability to the development of mental disorders, including depression. There has been a growing interest in the relationship between depression and inflammatory factors, because of its potential clinical and therapeutic implications. Inflammatory processes, which were originally understood as a response to infection and trauma, appear to play an important role in the pathogenesis of depression in the elderly...
April 4, 2024: BMC Geriatrics
https://read.qxmd.com/read/38563282/early-vital-sign-thresholds-associated-with-24-hour-mortality-among-trauma-patients-a-trauma-quality-improvement-program-tqip-study
#22
JOURNAL ARTICLE
Michael D April, Andrew D Fisher, Julie A Rizzo, Franklin L Wright, Julie M Winkle, Steven G Schauer
BACKGROUND: Identifying patients at imminent risk of death is critical in the management of trauma patients. This study measures the vital sign thresholds associated with death among trauma patients. METHODS: This study included data from patients ≥15 years of age in the American College of Surgeons Trauma Quality Improvement Program (TQIP) database. Patients with vital signs of zero were excluded. Documented prehospital and emergency department (ED) vital signs included systolic pressure, heart rate, respiratory rate, and calculated shock index (SI)...
April 2, 2024: Prehospital and Disaster Medicine
https://read.qxmd.com/read/38561883/challenges-in-diagnosis-and-treatment-of-male-hypogonadism
#23
JOURNAL ARTICLE
Dyah Purnamasari
Hypogonadism is a condition characterized by diminished or absent production of sex hormones by the testicles in men and the ovaries in women. Hypogonadism is classified into primary and secondary hypogonadism. Each type of hypogonadism can be caused by congenital and acquired factors. There are many factors that contribute to the occurrence of hypogonadism, including genetic and developmental disorders, infection, kidney disease, liver disease, autoimmune disorders, chemotherapy, radiation, surgery, and trauma...
January 2024: Acta Medica Indonesiana
https://read.qxmd.com/read/38555895/factors-associated-with-different-types-of-hip-fractures-among-elderly-patients-a-tertiary-hospital-in-pahang-a-retrospective-cross-sectional-study
#24
JOURNAL ARTICLE
R Mohd Yusoff, Z A Mulud, M Mohammadnezhad
INTRODUCTION: Hip fractures, predominantly due to decreased bone density and falls, significantly impact elderly health, disproportionately affecting women and placing a strain on healthcare resources. This study aims to conduct an indepth epidemiological analysis of hip fracture incidence among the elderly in Pahang, Malaysia, to inform better healthcare strategies. MATERIALS AND METHODS: In this retrospective study, medical records of patients admitted with hip fractures between 2019 and 2021 at Hospital Sultan Haji Ahmad Shah (HoSHAS) in Pahang were analyzed...
March 2024: Medical Journal of Malaysia
https://read.qxmd.com/read/38552637/the-extension-of-traumatic-subdural-hematoma-into-the-interhemispheric-fissure-is-associated-with-coagulation-disorders-a-retrospective-study
#25
JOURNAL ARTICLE
Lennart W Sannwald, Dag Moskopp, Mats L Moskopp
BACKGROUND:  This study investigates the correlation of the radiologic sign of interhemispheric subdural hematoma (iSDH) in different injury patterns with clinical coagulation disorders. It is hypothesized that the presence of iSDHs is correlated with clinical coagulation disorders in patients with traumatic brain injuries and subdural hematoma (SDH). METHODS:  Between January 1, 2020 and June 30, 2022, 154 patients with SDH were identified. Coagulation disorders were assessed using chart review and patients were divided into four groups: SDH without iSDH without further injuries (SDH), SDH with iSDH without further injuries (SDH + iSDH), SDH without iSDH with further brain injuries (Combi), SDH with iSDH with further injuries (Combi + iSDH)...
March 29, 2024: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://read.qxmd.com/read/38544993/comparison-of-intertan-and-pfna-internal-fixation-for-elderly-patients-with-intertrochanteric-fracture-a-retrospective-cohort-study
#26
JOURNAL ARTICLE
Li Li, Xing Fang, Jie Gao, Weizhen Han, Xiangan Kong
OBJECTIVE: To compare the clinical outcomes of InterTAN nail and proximal femoral nail antirotation (PFNA) internal fixation for the treatment of intertrochanteric fractures in the elderly. METHODS: We retrospectively reviewed the clinical records of 151 elderly patients with intertrochanteric fractures treated in The Second People's Hospital of Hefei from October 2019 to December 2021. Among them, 73 patients had undergone InterTAN (InterTAN group) and 78 patients had undergone PFNA (PFNA group) internal fixation...
2024: Pakistan Journal of Medical Sciences Quarterly
https://read.qxmd.com/read/38544542/does-early-and-late-weight-bearing-have-an-effect-on-the-results-of-elderly-tibial-plateau-fractures-with-internal-fixation-a-multicenter-tron-group-study
#27
JOURNAL ARTICLE
Yoshito Sudo, Yasuhiko Takegami, Katsuhiro Tokutake, Keita Shimizu, Keita Naruse, Tetsuro Takatsu, Shiro Imagama
INTRODUCTION: There is still no consensus on the length of the non-bearing period required for tibial plateau fractures (TPFs) treated surgically. Several studies showed that full weight bearing immediately postoperatively does not affect fixation or cause joint collapse in patients with TPF. While there are concerns about weight bearing in the elderly due to fragile bone quality, their physical disability often makes it difficult to carry out activities of daily life when weight bearing is not allowed...
April 2024: Indian Journal of Orthopaedics
https://read.qxmd.com/read/38544502/etiology-and-characteristics-of-patients-presenting-with-eyelid-lacerations-at-a-level-1-trauma-center
#28
JOURNAL ARTICLE
Abdelhalim A Awidi, Jiawei Zhao, Ximin Li, Fatemeh Rajaii, Meleha Ahmad, Adrianna Jensen, Fasika A Woreta
PURPOSE: To investigate the etiology and demographic associations of patients presenting with eyelid lacerations to a US level 1 trauma center emergency department (ED). PATIENT AND METHODS: A retrospective chart review of all patients with eyelid lacerations presenting to the ED at a single level 1 trauma center was performed. Eyelid lacerations were categorized as simple eyelid lacerations, eyelid lacerations with eyelid margin involvement, and eyelid lacerations with nasolacrimal system involvement...
2024: Clinical Ophthalmology
https://read.qxmd.com/read/38538583/the-effect-of-frailty-in-predicting-outcomes-of-rib-fractures-among-elderly-patients
#29
JOURNAL ARTICLE
Emily H Johnson, Valerie Brockman, Nathan Schmoekel, Thomas J Schroeppel
INTRODUCTION: Rib fractures are consequential injuries for geriatric trauma patients. Frailty has been associated with adverse outcomes in this population. The Rib Fracture Frailty Index (RFF) and 5-factor modified Frailty Index (mFI) are 2 validated frailty metrics. Research assessing inclusion of frailty metrics in geriatric rib fractures triage protocols is limited. METHODS: A retrospective cohort study was performed for trauma patients ≥50 years old with rib fractures admitted to a Level I trauma center, which currently uses percent predicted forced vital capacity (FVC%) to triage rib fractures patients...
March 27, 2024: American Surgeon
https://read.qxmd.com/read/38532264/the-effect-of-a-hip-fragility-pathway-on-outcomes-of-ground-level-falls-in-the-elderly
#30
JOURNAL ARTICLE
Jack Nadaud, Eric Heidel, Brian Daley, Catherine McKnight
Fragility hip fractures result from low energy mechanisms and are associated with morbidity and mortality, especially in the elderly. We examined outcomes 2 years before and after implementation of a fragility fracture program. The pathway involves emergency department clearance and admission by a medical service with orthopedic consultation. Demographics include age, gender, fracture location, injury severity score (ISS), and ASA. Outcomes include DVT/PE, mortality, disposition, non-operative rate, ICU admission, time to surgery (TTS), length of stay (LOS), and admission service...
March 26, 2024: American Surgeon
https://read.qxmd.com/read/38528491/association-between-admission-albumin-levels-and-30-day-readmission-after-hip-fracture-surgery-in-geriatric-patients-a-propensity-score-matched-study
#31
JOURNAL ARTICLE
Wanyun Tang, Wei Yao, Wei Wang, Wenbo Ding, Xiaomin Ni, RenJian He
PURPOSE: This study aimed to evaluate the correlation admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients. METHODS: In this retrospective cohort study, 1270 geriatric patients admitted for hip fractures to a level I trauma center were included. Patients were stratified by clinical thresholds and albumin level quartiles. The association between admission albumin levels and 30-day readmission risk was assessed using multivariate logistic regression and propensity score-matched analyses...
March 25, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38527944/major-low-energy-trauma-results-in-non-specific-immunoglobulin-generation-without-evidence-for-specific-autoantibody-production-a-prospective-cohort-study
#32
JOURNAL ARTICLE
Henrik Eckardt, Nicolas Bless, Ingmar Heijnen, Mario Morgenstern, Josephine Nehring, Andrea Kieninger-Gräfitsch, Martine Bouchenaki, Vanessa Durandin, Silke Purschke, Ina Schmidt, Loraine Pascale Kouba, Marten Trendelenburg, Eliska Potlukova
Cellular debris resulting from large trauma might overwhelm the scavenger mechanisms and lead to autoimmune reactions. We analysed whether a major well-defined trauma in humans induces laboratory signs of transient autoimmunity in the months after the insult. We included 50 patients with pertrochanteric femur fracture undergoing intramedullary nail osteosynthesis in a prospective cohort study and followed them at 3-4 days, 6 weeks, 12 weeks and 12 months postoperatively. By standard techniques, we assessed levels of total immunoglobulins, anti-nuclear antibodies (ANA), anti-cardiolipin antibodies, anti-dsDNA antibodies and anti-C1q antibodies, as well as antibodies against cytomegalovirus (CMV) as a control...
March 25, 2024: Scandinavian Journal of Immunology
https://read.qxmd.com/read/38516934/consensus-on-managing-open-ankle-fractures-in-the-frail-patient
#33
JOURNAL ARTICLE
Enis Guryel, Jo McEwan, Amir A Qureshi, Alastair Robertson, Raju Ahluwalia, Mark Baxter, Lyndon Mason, Will Eardley, Iain McFadyen, Alex Trompeter, Anna V Giblin, Bob Handley, Om Lahoti
AIMS: Ankle fractures are common injuries and the third most common fragility fracture. In all, 40% of ankle fractures in the frail are open and represent a complex clinical scenario, with morbidity and mortality rates similar to hip fracture patients. They have a higher risk of complications, such as wound infections, malunion, hospital-acquired infections, pressure sores, veno-thromboembolic events, and significant sarcopaenia from prolonged bed rest. METHODS: A modified Delphi method was used and a group of experts with a vested interest in best practice were invited from the British Foot and Ankle Society (BOFAS), British Orthopaedic Association (BOA), Orthopaedic Trauma Society (OTS), British Association of Plastic & Reconstructive Surgeons (BAPRAS), British Geriatric Society (BGS), and the British Limb Reconstruction Society (BLRS)...
March 22, 2024: Bone & joint open
https://read.qxmd.com/read/38512076/surgical-versus-non-surgical-management-of-lateral-compression-type-1-pelvic-fracture-in-adults-60-years-and-older-the-l1fe-rct
#34
JOURNAL ARTICLE
Elizabeth Cook, Joanne Laycock, Dhanupriya Sivapathasuntharam, Camila Maturana, Catherine Hilton, Laura Doherty, Catherine Hewitt, Catriona McDaid, David Torgerson, Peter Bates
BACKGROUND: Lateral compression type-1 pelvic fractures are a common fragility fracture in older adults. Patients who do not mobilise due to ongoing pain are at greater risk of immobility-related complications. Standard treatment in the United Kingdom is provision of pain relief and early mobilisation, unlike fragility hip fractures, which are usually treated surgically based on evidence that early surgery is associated with better outcomes. Currently there is no evidence on whether patients with lateral compression type-1 fragility fractures would have a better recovery with surgery than non-surgical management...
March 2024: Health Technology Assessment: HTA
https://read.qxmd.com/read/38510641/evaluation-of-perioperative-care-and-drivers-of-cost-in-geriatric-thoracolumbar-trauma
#35
JOURNAL ARTICLE
Omar H Tarawneh, Rajkishen Narayanan, Michael McCurdy, Tariq Z Issa, Yunsoo Lee, Olivia Opara, Nicholas B Pohl, Alexa Tomlak, Matthew Sherman, Jose A Canseco, Alan S Hilibrand, Alexander R Vaccaro, Gregory D Schroeder, Christopher K Kepler
INTRODUCTION: As the population of elderly patients continues to rise, the number of these individuals presenting with thoracolumbar trauma is expected to increase. RESEARCH QUESTION: To investigate thoracolumbar fusion outcomes for patients with vertebral fractures as stratified by decade. Secondarily, we examined the variability of cost across age groups by identifying drivers of cost of care. MATERIALS AND METHODS: We queried the United States Nationwide Inpatient Sample(NIS) for adult patients undergoing spinal fusion for thoracolumbar fractures between 2012 and 2017...
2024: Brain Spine
https://read.qxmd.com/read/38510601/outcome-of-traumatic-thoracolumbar-spine-fractures-in-elderly-a-systematic-review
#36
REVIEW
J van Tiel, T Tan, J Tee, T E Marion, F C Öner, J P H J Rutges
INTRODUCTION: Adequate guidelines for treatment of people over 65 years, suffering traumatic thoracolumbar spine fractures without neurologic deficit, are currently lacking. RESEARCH QUESTION: The aim of this study was to systematically review the available literature regarding the outcome of conservative and surgical treatment of thoracolumbar spinal trauma in elderly patients. MATERIAL AND METHODS: A systematic review according the PRISMA guidelines was performed...
2024: Brain Spine
https://read.qxmd.com/read/38505372/investigating-length-of-stay-patterns-and-its-predictors-in-the-south-wales-trauma-network
#37
JOURNAL ARTICLE
Zihao Wang, Bahman Rostami-Tabar, Jane Haider, Mohamed Naim, Javvad Haider
BACKGROUND: Length of stay (LOS) is frequently employed as a performance metric for trauma care. Following the establishment of the trauma network worldwide, the assessment and prediction of LOS in different levels of trauma centres have been extensively studied. However, assessing the total patient length of stay from a whole trauma network perspective is unclear. The objective of this study was to systematically analyse the overall Length of Stay (LOS) pattern within the SWTN before its establishment and in the immediate time after its foundation and, secondly, to assess the association between relevant impact factors and LOS...
2024: Adv Rehabil Sci Pract
https://read.qxmd.com/read/38500429/-clinical-diagnosis-and-treatment-of-14-cases-of-scar-cancer-ulcer-wound-on-head-and-face
#38
JOURNAL ARTICLE
Xinchong Chen, Guangtao Huang
OBJECTIVE: To analyze the clinical characteristics of scar cancer ulcer wound of head and face, and to investigate its diagnosis and treatment. METHODS: The clinical data of 14 patients with head and facial scar cancer ulcer wounds who met the selection criteria and admitted between January 2021 and March 2022 were retrospectively analyzed. There were 8 males and 6 females. The age of onset ranged from 21 to 81 years with an average age of 61.6 years. The incubation period ranged from 1 month to 70 years, with a median of 4 years...
March 15, 2024: Chinese Journal of Reparative and Reconstructive Surgery
https://read.qxmd.com/read/38496400/an-immune-signature-of-postoperative-cognitive-decline-in-elderly-patients
#39
Franck Verdonk, Amélie Cambriel, Julien Hedou, Ed Ganio, Grégoire Bellan, Dyani Gaudilliere, Jakob Einhaus, Maximilian Sabayev, Ina A Stelzer, Dorien Feyaerts, Adam T Bonham, Kazuo Ando, Benjamin Choisy, David Drover, Boris Heifets, Fabrice Chretien, Nima Aghaeepour, Martin S Angst, Serge Molliex, Tarek Sharshar, Raphael Gaillard, Brice Gaudilliere
UNLABELLED: Postoperative cognitive decline (POCD) is the predominant complication affecting elderly patients following major surgery, yet its prediction and prevention remain challenging. Understanding biological processes underlying the pathogenesis of POCD is essential for identifying mechanistic biomarkers to advance diagnostics and therapeutics. This longitudinal study involving 26 elderly patients undergoing orthopedic surgery aimed to characterize the impact of peripheral immune cell responses to surgical trauma on POCD...
March 5, 2024: bioRxiv
https://read.qxmd.com/read/38496181/arriving-at-skinted-surgery-of-the-knee-injury-to-the-infrapatellar-branch-of-the-saphenous-nerve-traumatic-eczematous-dermatitis-a-case-report
#40
KavyaDeepu R M, Mohnish Sekar
Surgery of the knee, injury to the infrapatellar branch of the saphenous nerve, traumatic eczematous dermatitis (SKINTED) is a postsurgical localized dermatitis specifically linked to total knee arthroplasty (TKA). It is due to autonomic denervation following surgically inflicted nerve injury. It develops several months to years following a surgical trauma. It is being referred to by various names in the literature. Locoregional immune dysfunction due to lymphatic injury after surgery is the currently accepted theory...
February 2024: Curēus
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