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https://www.readbyqxmd.com/read/27933408/twelve-weeks-progressive-resistance-training-combined-with-protein-supplementation-beyond-habitual-intakes-increases-upper-leg-lean-tissue-mass-muscle-strength-and-extended-gait-speed-in-healthy-older-women
#1
Peter Francis, William Mc Cormack, Clodagh Toomey, Catherine Norton, Jean Saunders, Emmet Kerin, Mark Lyons, Philip Jakeman
The age-related decline in functional capability is preceded by a reduction in muscle quality. The purpose of this study was to assess the combined effects of progressive resistance training (PRT) and protein supplementation beyond habitual intakes on upper leg lean tissue mass (LTM), muscle quality and functional capability in healthy 50-70 years women. In a single-blinded, randomized, controlled design, 57 healthy older women (age 61.1 ± 5.1 years, 1.61 ± 0.65 m, 65.3 ± 15.3 kg) consumed 0.33 g/kg body mass of a milk-based protein matrix (PRO) for 12 weeks...
December 8, 2016: Biogerontology
https://www.readbyqxmd.com/read/27933140/mitigating-pharmaceutical-waste-exposures-policy-and-program-considerations
#2
EDITORIAL
Eric D Amster
Pharmaceutical disposal and the environmental fate of medication metabolites directly impacts the public's health in two significant ways: accidental medication ingestion of pharmaceuticals that were not disposed of properly results in inadvertent toxicity; and environmental health consequences of pharmaceuticals that were inappropriately disposed and which contaminate municipal water supply. In reviewing the effectiveness of medication disposal policy globally, it is crucial to not only determine which policies are effective but also to assess why they are effective...
2016: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/27932937/effect-of-electrolyzed-high-ph-alkaline-water-on-blood-viscosity-in-healthy-adults
#3
Joseph Weidman, Ralph E Holsworth, Bradley Brossman, Daniel J Cho, John St Cyr, Gregory Fridman
BACKGROUND: Previous research has shown fluid replacement beverages ingested after exercise can affect hydration biomarkers. No specific hydration marker is universally accepted as an ideal rehydration parameter following strenuous exercise. Currently, changes in body mass are used as a parameter during post-exercise hydration. Additional parameters are needed to fully appreciate and better understand rehydration following strenuous exercise. This randomized, double-blind, parallel-arm trial assessed the effect of high-pH water on four biomarkers after exercise-induced dehydration...
2016: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/27932041/source-apportionment-and-health-risk-assessment-of-heavy-metals-in-soil-for-a-township-in-jiangsu-province-china
#4
Yanxue Jiang, Sihong Chao, Jianwei Liu, Yue Yang, Yanjiao Chen, Aichen Zhang, Hongbin Cao
Human activities contribute greatly to heavy metal pollution in soils. Concentrations of 15 metal elements were detected in 105 soil samples collected from a typical rural-industrial town in southern Jiangsu, China. Among them, 7 heavy metals-lead, copper, zinc, arsenic, chromium, cadmium, and nickel-were considered in the health risk assessment for residents via soil inhalation, dermal contact, and/or direct/indirect ingestion. Their potential sources were quantitatively apportioned by positive matrix factorization using the data set of all metal elements, in combination with geostatistical analysis, land use investigation, and industrial composition analysis...
December 5, 2016: Chemosphere
https://www.readbyqxmd.com/read/27931246/increased-alternate-splicing-of-htr2c-in-a-mouse-model-for-prader-willi-syndrome-leads-disruption-of-5ht2c-receptor-mediated-appetite
#5
Alastair S Garfield, Jennifer R Davies, Luke K Burke, Hannah V Furby, Lawrence S Wilkinson, Lora K Heisler, Anthony R Isles
Alternate splicing of serotonin (5-hydroxytryptamine; 5-HT) 2C receptor (5-HT2CR) pre-RNA is negatively regulated by the small nucleolar RNA, Snord115, loss of which is observed in nearly all individuals with Prader-Willi Syndrome (PWS), a multigenic disorder characterised by hyperphagia and obesity. Given the role of the 5-HT2CR in the regulation of ingestive behaviour we investigated the pathophysiological implications of Snord115 deficiency on 5-HT2CR regulated appetite in a genotypically relevant PWS mouse model (PWS-IC)...
December 8, 2016: Molecular Brain
https://www.readbyqxmd.com/read/27931130/exposures-to-traditional-automatic-dishwashing-tablets-and-a-comparison-with-exposures-to-soluble-film-tablets-reported-to-the-united-kingdom-national-poisons-information-service-2008-2015
#6
Rachael Day, Michael Eddleston, Simon H L Thomas, John P Thompson, J Allister Vale
INTRODUCTION: Traditional automatic dishwashing tablets are contained within an external wrapper that requires removal prior to use. OBJECTIVE: To determine the toxicity of traditional tablets and to compare this with our previously reported experience of soluble film dishwashing tablets. METHODS: Telephone enquiries regarding traditional tablets were analysed retrospectively for the period January 2008 to December 2015. RESULTS: Traditional tablets: There were 503 enquiries relating to 492 patients who had been exposed to a traditional tablet...
December 8, 2016: Clinical Toxicology
https://www.readbyqxmd.com/read/27931108/caustic-esophageal-injury-by-impaction-of-cell-batteries
#7
Francisco José García Fernández, Rafael León Montañés, Juan Manuel Bozada Garcia
The ingestion of cell batteries can cause serious complications (fistula, perforation or stenosis) at the esophageal level. The damage starts soon after ingestion (approximately 2 hours) and is directly related to the amount of time the battery is lodged in said location, the amount of electrical charge remaining in the battery, and the size of the battery itself. Injury is produced by the combination of electrochemical and chemical mechanisms and pressure necrosis. The ingestion of multiple cells and a size > = 20 mm are related with more severe and clinically significant outcomes...
December 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27930996/stabilization-of-mercury-in-sediment-by-using-biochars-under-reducing-conditions
#8
Peng Liu, Carol J Ptacek, David W Blowes, Y Zou Finfrock, Robert A Gordon
Mercury (Hg) is widely distributed in different localities around the world and poses a serious health threat to humans, especially when ingested in the form of methylmercury (MeHg). Efforts have been directed toward decreasing the production of MeHg by converting Hg to stable forms. Activated carbon and biochar have been evaluated as stabilization agents for Hg in contaminated sediments. However, the long-term fate of Hg stabilized by these materials remains unclear. Here, we compare the effectiveness of Hg stabilization using two biochars prepared from switchgrass at 300°C (lowT) and 600°C (highT)...
November 10, 2016: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/27930968/transformation-and-bioaccessibility-of-lead-induced-by-steamed-bread-feed-in-the-gastrointestinal-tract
#9
Junhong Kan, Jingke Sima, Xinde Cao
Accidental ingestion of contaminated soil has been recognized as an important pathway of human exposure to lead (Pb), especially for children through hand-to-mouth activities. Intake of food following the soil ingestion may affect the bioaccessibility of Pb in the gastrointestinal tract. In this study, the effect of steamed bread on the transformation and subsequent bioaccessibility of Pb in two soils was determined by the physiologically based extraction test (PBET). Two compounds, Pb(NO3)2 and PbCO3, were included in the evaluation for comparison...
December 5, 2016: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/27930651/maternal-and-fetal-pharmacokinetics-of-oral-radiolabeled-and-authentic-bisphenol-a-in-the-rhesus-monkey
#10
Catherine A VandeVoort, Roy R Gerona, Frederick S Vom Saal, Alice F Tarantal, Patricia A Hunt, Anne Hillenweck, Daniel Zalko
The present study was conducted in pregnant rhesus monkeys to determine the rapidity and extent to which BPA reaches the fetal compartment following oral ingestion, and the 24-hr fate of BPA. To assess metabolism changes during the course of pregnancy, we compared BPA biotransformation during the second and third trimesters in the same animals, measuring the levels of sulfated, gluronidated, and free BPA in maternal serum, amniotic fluid, and fetal serum. All animals showed measurable unconjugated and conjugated BPA in the fetal compartment and slow clearance compared to maternal serum...
2016: PloS One
https://www.readbyqxmd.com/read/27930507/thoracic-spinal-epidural-abscess-caused-by-fishbone-perforation-a-case-report-and-review-of-literature
#11
Jian-Min Chen, Zhi-Yong Wang, Guo-Xin Ni
RATIONALE: Ingestion of a fishbone is a common cause of esophageal injury, but spinal epidural abscess (SEA) is a rare condition due to the esophageal penetration by a swallowed fishbone. Prompt diagnosis can be seldom made owing to incomplete patient history taking and difficulties in imaging evidence identification. PATIENT CONCERNS: We describe the case of a 62-year-old woman who was stuck in her throat by a fishbone, and complained of back pain, paresis of the lower limbs and fever, successively...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27930452/shorter-duration-time-trial-performance-and-recovery-is-not-improved-by-inclusion-of-protein-in-a-multiple-carbohydrate-supplement
#12
Anthony S Wolfe, Sallee A Brandt, Isaac Krause, Rachel Mavison, Josh Aponte, Lisa M Ferguson-Stegall
Ingesting multiple carbohydrate (CHO) types during exercise can improve endurance performance compared to single CHO only. Adding protein to a multiple CHO beverage has been shown to increase cycling time to exhaustion (TTE) compared to a single CHO beverage. However, it is unclear if improvements were due to multiple CHOs or protein, and TTE protocols are not representative of typical race events. This study investigated whether adding protein to a multiple CHO beverage improved performance and recovery in 2 same-day cycling time trials compared to isocaloric multiple CHO-only...
November 19, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27930447/carbohydrate-and-caffeine-improves-high-intensity-running-of-elite-rugby-league-interchange-players-during-simulated-match-play
#13
Jon S Clarke, Jamie Highton, Graeme L Close, Craig Twist
The study examined the effects of carbohydrate and caffeine ingestion on simulated rugby league interchange performance. Eight male elite rugby league forwards completed two trials of a rugby league simulation protocol for interchange players seven days apart in a randomized crossover design, ingesting either carbohydrate (CHO; 40 g·h-1) or carbohydrate and caffeine (CHO-C) (40 g·h-1 + 3 mg·kg-1) drink. Movement characteristics, heart rate, ratings of perceived exertion (RPE), and countermovement jump height (CMJ) were measured during the protocol...
November 19, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27930368/metal-contamination-in-environmental-media-in-residential-areas-around-romanian-mining-sites
#14
Iulia A Neamtiu, Souhail R Al-Abed, John L McKernan, Calin L Baciu, Eugen S Gurzau, Anca O Pogacean, Scott M Bessler
Hard-rock mining for metals, such as gold, silver, copper, zinc, iron and others, is recognized to have a significant impact on the environmental media, soil and water, in particular. Toxic contaminants released from mine waste to surface water and groundwater is the primary concern, but human exposure to soil contaminants either directly, via inhalation of airborne dust particles, or indirectly, via food chain (ingestion of animal products and/or vegetables grown in contaminated areas), is also, significant...
December 8, 2016: Reviews on Environmental Health
https://www.readbyqxmd.com/read/27929204/evidence-of-viscerally-mediated-cold-defence-thermoeffector-responses-in-man
#15
Nathan B Morris, Davide Filingeri, Mark Halaki, Ollie Jay
Sudomotor activity is modified by both warm and cold fluid ingestion during heat stress, independently of differences in core and skin temperatures, suggesting independent viscerally-mediated modification of thermoeffectors. The purpose of the present study was to determine whether visceral thermoreceptors modify shivering responses to cold stress. Ten males (27 ± 5y, 1.73 ± 0.06 m, 78.4 ± 10.7 kg) underwent whole-body cooling via 5 °C water perfusion-suit, on four occasions, to induce a steady-state shivering response, at which point two aliquots of 1...
November 7, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27929185/melatonin-and-hydroxytyrosol-protect-against-oxidative-stress-related-to-the-central-nervous-system-after-the-ingestion-of-three-types-of-wine-by-healthy-volunteers
#16
Javier Marhuenda, Sonia Medina, Pedro Martínez-Hernández, Simón Arina, Pilar Zafrilla, Juana Mulero, Camille Oger, Jean-Marie Galano, Thierry Durand, Federico Ferreres, Angel Gil-Izquierdo
Adrenic acid (AdA) and docosahexaenoic acid (DHA) peroxidation produces F2-dihomo-IsoPs and neuroprostanes, which have been related to oxidative damage in the central nervous system. Besides polyphenols, melatonin (MEL) and hydroxytyrosol (OHTyr) could be partly responsible for the antioxidant benefits of red wine (excluding colon derivatives). In order to elucidate whether these compounds are responsible for the protective antioxidant effects of red wine, a double-blind, crossover, placebo-controlled in vivo study - involving the intake of red wines and their native musts by healthy volunteers - was performed...
December 8, 2016: Food & Function
https://www.readbyqxmd.com/read/27929123/rnai-mediated-mortality-of-the-whitefly-through-transgenic-expression-of-double-stranded-rna-homologous-to-acetylcholinesterase-and-ecdysone-receptor-in-tobacco-plants
#17
Hassan Jamil Malik, Amir Raza, Imran Amin, Jodi A Scheffler, Brian E Scheffler, Judith K Brown, Shahid Mansoor
The whitefly Bemisia tabaci (Genn.) is a pest and vector of plant viruses to crop and ornamental plants worldwide. Using RNA interference (RNAi) to down regulate whitefly genes by expressing their homologous double stranded RNAs in plants has great potential for management of whiteflies to reduce plant virus disease spread. Using a Tobacco rattle virus-derived plasmid for in planta transient expression of double stranded RNA (dsRNA) homologous to the acetylcholinesterase (AChE) and ecdysone receptor (EcR) genes of B...
December 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27929093/plant-based-foods-containing-cell-wall-polysaccharides-rich-in-specific-active-monosaccharides-protect-against-myocardial-injury-in-rat-myocardial-infarction-models
#18
Sun Ha Lim, Yaesil Kim, Ki Na Yun, Jin Young Kim, Jung-Hee Jang, Mee-Jung Han, Jongwon Lee
Many cohort studies have shown that consumption of diets containing a higher composition of foods derived from plants reduces mortality from coronary heart disease (CHD). Here, we examined the active components of a plant-based diet and the underlying mechanisms that reduce the risk of CHD using three rat models and a quantitative proteomics approach. In a short-term myocardial infarction (MI) model, intake of wheat extract (WE), the representative cardioprotectant identified by screening approximately 4,000 samples, reduced myocardial injury by inhibiting apoptosis, enhancing ATP production, and maintaining protein homeostasis...
December 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27928597/effects-of-bacillus-cereus-endospores-on-free-living-protist-growth
#19
Susana S Santos, Niels Bohse Hendriksen, Hans Henrik Jakobsen, Anne Winding
We studied the predator-prey interactions between heterotrophic protists and endospores of Bacillus cereus group bacteria, in order to gain insight on survival and dispersal of B. cereus endospores in the environment. It has been hypothesised that the spore stage protects against digestion by predating protists. Therefore, experiments were carried out to investigate the impact of B. cereus endospores and vegetative cells, as the only food source, on individual amoeboid, flagellated and ciliated protists. The presence of fluorescent-labelled intracellular bacteria confirmed that B...
December 7, 2016: Microbial Ecology
https://www.readbyqxmd.com/read/27928177/reduction-of-serum-25-hydroxyvitamin-d-concentrations-with-intravenous-lipid-emulsion-in-a-dog
#20
Brittany Heggem Perry, Maureen McMichael, Markus Rick, Emily Jewell
The recommended daily allowance of vitamin D has been increased. Toxicosis in pets may increase as a result. A dog ingested ~ 200 000 IU of vitamin D, serum concentrations were above the reference range (RR) and decreased to the RR after lipid treatment. This is the first known report of lipid treatment for hypervitaminosis D.
December 2016: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
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