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https://www.readbyqxmd.com/read/27752210/a-comparative-study-of-trigger-point-therapy-with-local-anaesthetic-0-5%C3%A2-bupivacaine-versus-combined-trigger-point-injection-therapy-and-levosulpiride-in-the-management-of-myofascial-pain-syndrome-in-the-orofacial-region
#1
Pranav Gupta, Virendra Singh, Sujata Sethi, Arun Kumar
AIM: To compare the efficacy of combined local anesthetic injection with 0.5 % bupivacaine and levosulpiride versus local anesthetic injection alone on outcome measures including levels of pain intensity and depression in the management of myofascial pain syndrome in orofacial region. PATIENTS AND METHODS: This was a prospective, randomized, controlled and open-label comparative clinical study. Seventy-four patients diagnosed to have myofascial pain syndrome and fulfilling the inclusion criteria were enrolled for the study...
September 2016: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/27612466/a-randomised-placebo-controlled-trial-assessing-the-efficacy-of-an-oral-b-group-vitamin-in-preventing-the-development-of-chemotherapy-induced-peripheral-neuropathy-cipn
#2
Janet M Schloss, Maree Colosimo, Caroline Airey, Paul Masci, Anthony W Linnane, Luis Vitetta
INTRODUCTION: Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating side effect resulting from neurotoxic chemotherapeutic agents. This study aimed to assess the efficacy and safety of an oral B group vitamin compared to placebo, in preventing the incidence of CIPN in cancer patients undergoing neurotoxic chemotherapy. METHODS: A pilot, randomised, placebo-controlled trial was conducted. Newly diagnosed cancer patients prescribed with taxanes, oxaliplatin or vincristine were invited to participate...
January 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/27505989/potential-of-desensitizing-toothpastes-to-reduce-the-hydrogen-peroxide-diffusion-in-teeth-with-cervical-lesions
#3
Andrés Dávila-Sánchez, Andrés Fernando Montenegro, Arana-Gordillo Alfonso, Paulo Vitor Farago, Alessandro D Loguercio, Alessandra Reis
PURPOSE: To evaluate the occlusive potential of four toothpastes by atomic force microscopy (AFM) before and after bleaching and quantify the hydrogen peroxide (HP) diffusion into the pulp chamber after application of desensitizing toothpastes in teeth with cervical lesions. METHODS: In 52 human extracted premolars, 2-mm deep artificial cervical lesions (ACL) were prepared and rinsed with EDTA for 10 seconds. Then teeth were adapted in a brushing machine and brushed with one of the following toothpastes [Regular toothpaste with no occlusive compounds Colgate Cavity Protection (CP), Oral-B Pro Health (OB), Colgate ProRelief (PR) and Sensodyne Rapid Relief (RR)] under constant loading (250 g; 4...
June 2016: American Journal of Dentistry
https://www.readbyqxmd.com/read/27384682/laparoscopic-band-separated-one-anastomosis-gastric-bypass
#4
Oral B Ospanov
BACKGROUND: This video demonstrates laparoscopic band-separated one anastomosis gastric bypass-combining the advantages of banding and gastric bypass without stapler and cutter use. This is basically a gastrojejunal loop bypass above an obstructive band in the upper stomach. MATERIALS AND SURGICAL TECHNIQUE: An adjustable low pressure "Medsil" gastric band was introduced in the abdomen and retracted through the retrogastric tunnel. The front wall of the stomach below the band was displaced in the upward direction through the ring band, increasing the size of the anterior portion of the stomach pouch so that a gastroenteroanastomosis could be created at this point...
September 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27367193/-analysis-of-the-efficacy-and-safety-of-electric-toothbrushes-oral-b-with-oscillating-rotating-technology-in-%C3%A2-healthy-smile%C3%A2-program
#5
A I Nikolaev, N V Ginali, L M Tsepov, V R Shashmurina
The aim of study was to investigate the efficacy and safety of individual oral hygiene in adult patients by regular use of electric toothbrushes with the oscillating-rotating technology basing on data obtained during the implementation of «Healthy Smile» program. Questionnaires of 7022 dentists in Russia and Ukraine were used to assess personal experience of using Oral-B PC 5000 toothbrush. The dental status dynamics after regular use of Oral-B PC 500 tooth brush was evaluatedin 21 088 patients within 12 weeks...
2016: Stomatologii︠a︡
https://www.readbyqxmd.com/read/27122894/catecholaminergic-polymorphic-ventricular-tachycardia-a-rare-cause-of-cardiac-arrest-following-blunt-chest-trauma
#6
Isa Ozyilmaz, Sinem Ozyilmaz, Yakup Ergul, Celal Akdeniz, Volkan Tuzcu
UNLABELLED: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an electrophysiological disorder of a physically normal heart that occurs in children when the body is subjected to intense emotional or physical stress that causes adrenergic discharge. This troubling disease can be sporadic (spontaneous) or familial (genetic/inherited). Unfortunately, its associated ventricular tachycardia may cause sudden death, so early diagnosis of CPVT is very important. Treatment modalities include medical treatment, implantation of a cardioverter defibrillator, or surgical sympatectomy; but the implantable cardioverter defibrillator (ICD) should be the first choice in patients with a history of cardiac arrest...
July 2015: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/27110254/antifungal-effects-of-common-mouthwashes-on-candida-strains-colonized-in-the-oral-cavities-of-liver-transplant-recipients-in-south-iran-in-2014
#7
Ali Dehghani Nazhvani, Pardis Haddadi, Parisa Badiee, Seyed Ali Malekhoseini, Hadis Jafarian
BACKGROUND: Among the opportunistic microorganisms, fungi, particularly Candida, play an important role in the mortality of transplant recipients. Thus, controlling and preventing fungal colonizations in various parts of the body, including the oral cavity, can reduce the possibility of post-transplant invasive fungal infections. This can be done simply by using mouthwashes. OBJECTIVES: The current study aimed to determine the prevalence of fungal species of Candida within the oral cavities of liver transplant recipients, and to evaluate the effects on Candida colonization of different exposure times to common mouthwashes...
January 2016: Hepatitis Monthly
https://www.readbyqxmd.com/read/27097693/intralesional-versus-oral-chloroquine-in-cutaneous-leishmaniasis-comparison-of-outcome-duration-of-treatment-and-total-dose-of-drug
#8
Malik Muhammad Hanif, Khizra Akram, Ghulam Mustafa
OBJECTIVE: To compare intralesional versus oral chloroquine in cutaneous leishmaniasis and determine the cure rate, duration of treatment, and total dose of drug. STUDY DESIGN: Randomized controlled study. PLACE AND DURATION OF STUDY: Department of Dermatology, Sheikh Zayed Medical College/Hospital, Rahim Yar Khan, from November 2013 to June 2014. METHODOLOGY: Consecutive 86 patients of cutaneous leishmaniasis, with single to multiple lesions of various sizes were enrolled and divided randomly into group Aand B for the purpose of intralesional and oral chloroquine administration, respectively to compare the effect of the two routes on duration of treatment and total dose of the drug...
April 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27093772/stain-removal-efficacy-of-two-manual-toothbrushes
#9
RANDOMIZED CONTROLLED TRIAL
Lynn Roosa Friesen, Svetlana Farrell, Julie M Grender, Jill Underwood, Pam Cunningham, Renzo A Ccahuana-Vásquez
PURPOSE: To evaluate the dental stain removal efficacy of two commercially-available manual toothbrushes. METHODS: This was a randomized, examiner-blind, parallel-group, two treatment clinical trial of 2 weeks duration. Subjects qualifying for the study had a mean Modified Lobene Stain Index of ≥ 1.5 on at least two anterior teeth. Subjects were randomly allocated to one of two groups, receiving a test manual toothbrush (Oral-B 3D White Radiant) or a positive control (PC) manual brush to be used for 1 minute, twice daily for 2 weeks with a standard, anti-cavity fluoride dentifrice...
February 2016: American Journal of Dentistry
https://www.readbyqxmd.com/read/26846042/randomized-controlled-trial-comparing-a-powered-toothbrush-with-distinct-multi-directional-cleaning-action-to-a-manual-flat-trim-toothbrush
#10
RANDOMIZED CONTROLLED TRIAL
John Gallob, Luis R Mateo, Patricia Chaknis, Boyce M Morrison, Fotinos Panagakos
PURPOSE: To compare the plaque and gingivitis efficacy of a power toothbrush with distinct multi-directional cleaning action (Colgate® ProClinical® A1500 Power Toothbrush) against a manual flat-trim toothbrush (Oral-B Indicator). METHODS: This randomized control trial was a single-center, examiner-blind, parallel-group, design and assessed plaque removal after a single brushing, as well as plaque removal and gingivitis reduction after 4 weeks and 12 weeks of brushing...
December 2015: American Journal of Dentistry
https://www.readbyqxmd.com/read/26576865/eliminating-minimal-residual-disease-as-a-therapeutic-end-point-working-toward-cure-for-patients-with-cll
#11
REVIEW
Philip A Thompson, William G Wierda
Deep remission and prolonged disease-free survival can be achieved with first-line chemoimmunotherapy (CIT), such as combined fludarabine, cyclophosphamide, and rituximab, in the majority of patients with chronic lymphocytic leukemia (CLL). More modest results are reported with less intense regimens like obinutuzumab plus chlorambucil. Clinical assessment has limited sensitivity in detecting residual disease responsible for subsequent relapse, even including morphologic bone marrow (BM) evaluation. Multicolor flow cytometry and polymerase chain reaction (PCR)-based methods can detect minimal residual disease (MRD) to a sensitivity of ≥1:10,000 (10(-4))...
January 21, 2016: Blood
https://www.readbyqxmd.com/read/26437503/influence-of-colorant-solutions-in-properties-of-indirect-resin-composites
#12
Daniela Micheline Dos Santos, Adrielle Mendes De Paula, Liliane da Rocha Bonatto, Emily Vivianne Freitas Da Silva, Aljomar José Vechiato Filho, Amália Moreno, Marcelo Coelho Goiato
PURPOSE: To evaluate the influence of colorant solutions on color stability and surface roughness of indirect resin composites submitted to prior immersion in mouthwashes. METHODS: Five brands of indirect resin composites were assessed: Adoro, Resilab, Cristobal, Sinfony and Epricord. The specimens were immersed in five different solutions (n = 10): four mouthwashes (Listerine, Oral-B, Plax, Periogard) and artificial saliva (control). 60 hours after immersion in mouthwashes, the specimens were exposed to coffee solution...
August 2015: American Journal of Dentistry
https://www.readbyqxmd.com/read/26393163/an-observational-study-to-evaluate-the-prevalence-of-erectile-dysfunction-ed-and-prescribing-pattern-of-drugs-in-patients-with-ed-visiting-an-andrology-specialty-clinic-mumbai-2012-14
#13
Amit S Mutha, Vijay R Kulkarni, Sagar B Bhagat, Amit S Beldar, Sadiq B Patel
INTRODUCTION: Erectile dysfunction (ED) is a common occurrence and its incidence is expected to increase significantly along with the increase in various lifestyle diseases. The drug utilization for ED is very low. Also, studies describing the prescription pattern in ED are lacking. MATERIALS AND METHODS: We conducted a retrospective cross-sectional observational study, including a drug utilization analysis, of 606 prescriptions as per the standard guidelines (WHO and STROBE)...
July 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26392897/training-veterinarians-and-agricultural-advisers-on-a-novel-tool-for-tail-biting-prevention
#14
A L Vom Brocke, D P Madey, M Gauly, L Schrader, S Dippel
INTRODUCTION: Many health and welfare problems in modern livestock production are multifactorial problems which require innovative solutions, such as novel risk assessment and management tools. However, the best way to distribute such novel - and usually complex - tools to the key applicants still has to be discussed. MATERIALS AND METHODS: This paper shares experiences from distributing a novel tail biting prevention tool ('SchwIP') to 115 farm advisers and 19 veterinarians in 23 one-day workshops...
2015: Veterinary Record Open
https://www.readbyqxmd.com/read/26392664/primary-bilateral-plasmablastic-lymphoma-of-the-testis-in-a-human-immunodeficiency-virus-positive-man
#15
Rama Kumari Badyal, Amarjit S Kataria
Human immunodeficiency virus (HIV)-related lymphomas are predominantly aggressive B-cells lymphomas. The most prevalent of the HIV-related lymphomas are diffuse large B-cell non-Hodgkin's lymphoma (NHL), which includes primary central nervous system lymphoma, and Burkitt lymphoma, whereas primary effusion lymphoma, plasmablastic lymphoma (PBL), and classic Hodgkin lymphoma are far less frequent. Of these, PBL is relatively uncommon and displays a distinct predilection for presentation in the oral cavity. In this manuscript, we report a primary testicular form of PBL in 44 year-old Border Security HIV positive patient who presented with bilateral testicular swelling of 1-year duration...
January 2015: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/26390730/-bacterial-infections-in-the-early-period-after-allogeneic-bone-marrow-transplantation
#16
V N Vavilov, M Iu Aver'ianova, S N Bondarenko, N V Stancheva, L S Zubarovskaia, B V Afanas'ev
AIM: To study the incidence and risk factors of bacterial infections and the efficiency of empirical antibacterial therapy in patients in the early period after allogeneic hematopoietic stem cell transplantation (allo-HSCT). SUBJECTS AND METHODS: The study included 155 patients who had undergone allo-HSCT. Myeloablative conditioning was used in 39% of the patients. All the patients with neutropenia (NP) received antibiotic prophylaxis with fluoroquinolones until recovery of white blood cell counts or before systemic antibiotic therapy...
2015: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/26390114/a-simple-lc-ms-method-for-determination-of-cyasterone-in-rat-plasma-application-to-a-pilot-pharmacokinetic-study
#17
Fuqiang Li, Guangyu Li, Jinsong Zhao, Jun Xiao, Zaoxia Liu, Guanfang Su
A simple, specific, and sensitive liquid chromatography-mass spectrometry (LC-MS) method for determination of cyasterone in rat plasma was developed in our laboratory. Cucurbitacin B was used as an internal standard (IS). After protein precipitation with twofold volume of acetonitrile, the analyte and IS were separated on a Luna C18 column (100 × 4.6 mm, i.d., 3.0 µm; Phenomenex) by isocratic elution with acetonitrile-water (80:20, v/v) as the mobile phase at a flow rate of 0.4 mL/min. An electrospray ionization source was applied and operated in the positive ion mode; selected ion monitoring scan mode was used for quantification, and the target ions m/z 543...
June 2016: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/26389948/consumption-of-polyphenol-rich-zingiber-zerumbet-rhizome-extracts-protects-against-the-breakdown-of-the-blood-retinal-barrier-and-retinal-inflammation-induced-by-diabetes
#18
Thing-Fong Tzeng, Tang-Yao Hong, Yu-Cheng Tzeng, Shorong-Shii Liou, I-Min Liu
The present study investigates the amelioration of diabetic retinopathy (DR) by Zingiber zerumbet rhizome ethanol extracts (ZZRext) in streptozotocin-induced diabetic rats (STZ-diabetic rats). ZZRext contains high phenolic and flavonoid contents. STZ-diabetic rats were treated orally with ZZRext (200, 300 mg/kg per day) for three months. Blood-retinal barrier (BRB) breakdown and increased vascular permeability were found in diabetic rats, with downregulation of occludin, and claudin-5. ZZRext treatment effectively preserved the expression of occludin, and claudin-5, leading to less BRB breakdown and less vascular permeability...
September 2015: Nutrients
https://www.readbyqxmd.com/read/26388830/cathepsin-b-is-a-new-drug-target-for-traumatic-brain-injury-therapeutics-evidence-for-e64d-as-a-promising-lead-drug-candidate
#19
REVIEW
Gregory Hook, J Steven Jacobsen, Kenneth Grabstein, Mark Kindy, Vivian Hook
There is currently no therapeutic drug treatment for traumatic brain injury (TBI) despite decades of experimental clinical trials. This may be because the mechanistic pathways for improving TBI outcomes have yet to be identified and exploited. As such, there remains a need to seek out new molecular targets and their drug candidates to find new treatments for TBI. This review presents supporting evidence for cathepsin B, a cysteine protease, as a potentially important drug target for TBI. Cathepsin B expression is greatly up-regulated in TBI animal models, as well as in trauma patients...
2015: Frontiers in Neurology
https://www.readbyqxmd.com/read/26388784/the-protective-effects-of-oral-low-dose-quercetin-on-diabetic-nephropathy-in-hypercholesterolemic-mice
#20
Isabele B S Gomes, Marcella L Porto, Maria C L F S Santos, Bianca P Campagnaro, Agata L Gava, Silvana S Meyrelles, Thiago M C Pereira, Elisardo C Vasquez
AIMS: Diabetic nephropathy (DN) is one of the most important causes of chronic renal disease, and the incidence of DN is increasing worldwide. Considering our previous report (Gomes et al., 2014) indicating that chronic treatment with oral low-dose quercetin (10 mg/Kg) demonstrated anti-oxidative, anti-apoptotic and renoprotective effects in the C57BL/6J model of DN, we investigated whether this flavonoid could also have beneficial effects in concurrent DN and spontaneous atherosclerosis using the apolipoprotein E-deficient mouse (apoE(-/-))...
2015: Frontiers in Physiology
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