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Ali Firat Sarp, Yeliz Pekcevik
Lipomatosis of the nerve, also known as fibrolipomatous hamartoma, is characterized by the infiltration of the nerve by fibro-fatty tissue. The affected nerve becomes thicker, and it simulates a mass lesion. Lipomatosis usually affects the median nerve and lipomatosis of the sciatic nerve is extremely rare. Magnetic resonance imaging (MRI) is the key to diagnosis, and it is usually pathognomonic. In this report, MRI and diffusion-weighted MRI findings of a case of a giant sciatic nerve lipomatosis without macrodactyly are presented...
April 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
Q H Liao, K H Zhu
No abstract text is available yet for this article.
September 8, 2016: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
B Salazard, C Philandrianos, A Gaudeuille
Malformations and deformations of the forefoot are a frequent reason for consultation. The most frequent malformations viewed at birth are syndactylies (second web space), clinodactylies (quintus varus, halllux), polydactylies (hallux, fifth toe). The macrodactylies, hypoplasia, amniotic bands are rare. The management of these defects requires knowledge of surgery adult foot, plastic surgery and especially collaboration with physiotherapists, podiatrists and orthotists. The fast growth of the foot the first year and the development of walking at one year require to start early the treatment of deformations and to anticipate the evolution of malformations...
October 2016: Annales de Chirurgie Plastique et Esthétique
Rohan K Henry, Monika Chaudhari, Sasigarn A Bowden
No abstract text is available yet for this article.
October 2016: Clinical Pediatrics
H-J Lee, P-T Kim, S-J Lee, H-J Kim, I-H Jeon, I Seo
: We report the long-term results of a single-stage reduction procedure for the treatment of macrodactyly. Six patients (eight cases) were included. These patients underwent a single-stage operation that included debulking with resection of the hypertrophied digital nerve and distal interphalangeal joint fusion or corrective osteotomy. Plain radiographs and functional parameters were assessed. Aesthetic improvement was achieved in all patients. The mean ratios of the lengths and circumference differences between the affected digit and the corresponding normal digit on the other hand were 1:1 and 1:1, respectively...
August 11, 2016: Journal of Hand Surgery, European Volume
Walid Moudrous, Jasper van der Ree, Fiek van Tilborg, Leo H Visser
No abstract text is available yet for this article.
October 2016: Practical Neurology
Peter M Waters, Bryce T Gillespie
Macrodactyly of the hand is a rare condition. Although the underlying mechanism is being more fully elucidated, surgical intervention is typically required to improve the size and function of the affected digits. However, when an involved digit(s) is rapidly progressive in size, ray resection amputation may be the most appropriate treatment. Clinical cases are presented to illustrate single-digit and 2-digit ray resection amputations for progressive macrodactyly.
August 2016: Journal of Hand Surgery
Jawad Fares, Nizar Natout, Youssef Fares
We report a rare case of neural fibrolipoma (lipofibromatous hamartoma) of the median nerve of the hand. An 18-year-old male complaining of progressive and chronic macrodactyly of his thumb of the left hand, with neurological complains, was admitted to the hospital. Magnetic resonance (MR) evaluation revealed fibro-fatty infiltration of the median nerve at the level of the carpal tunnel, and the terminal branches of the median nerve in the thumb and index. The pathological examination of excised tissue confirmed the diagnosis of neural fibrolipoma of the terminal branch of the median nerve in his thumb...
January 2016: Le Journal Médical Libanais. the Lebanese Medical Journal
Mariana Soeiro E Sá, Oana Moldovan, Ana Berta Sousa
Macrodactyly in the context of tuberous sclerosis complex (TSC) is a known but rare manifestation. We report the case of a boy diagnosed with TSC at 2 years and 4 months of age, presenting with bilateral macrodactyly of the first three fingers of both hands, with underlying radiographic changes, in whom molecular analysis identified a frameshift mutation on the TSC1 gene (encoding hamartin), leading to a premature stop codon. We reviewed the literature for reported cases of TSC patients with the same manifestation...
July 2016: American Journal of Medical Genetics. Part A
Ranjan Agrawal, Cheena Garg, Arjun Agarwal, Parbodh Kumar
Lipofibromatous hamartoma (LFH) is a rare, benign fibrofatty tumor composed of a proliferation of mature adipocytes within peripheral nerves, which form a palpable neurogenic mass. It affects the median nerve in 66-80% of cases, causing pain and sensory and motor deficits in the affected nerve distribution. Patients typically present with gradually enlarging nontender lesions in the distribution of the affected nerve. The lesion is also seen to be associated with macrodactyly. The pathophysiology of LFH is unknown...
January 2016: Indian Journal of Pathology & Microbiology
Kornélia Tripolszki, Rachel Knox, Victoria Parker, Robert Semple, Katalin Farkas, Adrien Sulák, Emese Horváth, Márta Széll, Nikoletta Nagy
Isolated macrodactyly (OMIM 155500) belongs to a heterogeneous group of overgrowth syndromes. It is a congenital anomaly resulting in enlargement of all tissues localized to the terminal portions of a limb and caused by somatic mutations in the phosphatidylinositol 3-kinase catalytic alpha (PIK3CA, OMIM 171834) gene. Here we report a Hungarian girl with macrodactyly and syndactyly. Genetic screening at hotspots in the PIK3CA gene identified a mosaic mutation (c.1624G > A, p.Glu542Lys) in the affected tissue, but not in the peripheral blood...
April 2016: European Journal of Medical Genetics
Xianying Zhang, Yi Liu, Bin Xiao, Yuhuan Li
Congenital enlargement of one or several digits of the foot, known as macrodactyly, is a rare malformation. Macrodactyly impedes foot development and affects function and gait. Here, we describe a surgical technique used to correct macrodactyly in two pediatric patients. We performed amputation of the enlarged phalanx and debulking of the soft tissues to construct a normal-sized digit. This precise technique involves a simple surgical plan that preserves the metatarsus and cuneiform and does not result in a wide plantapedis...
March 2016: Journal of Pediatric Orthopedics. Part B
Kenichi Mishima, Hiroshi Kitoh, Izumi Kadono, Masaki Matsushita, Hiroshi Sugiura, Sachi Hasegawa, Akiko Kitamura, Yoshihiro Nishida, Naoki Ishiguro
Leg-length discrepancy greater than 2 to 2.5 cm can potentially have an adverse effect on our walking and standing mechanisms and requires proper correction involving surgical treatment. However, for minor leg-length discrepancy in childhood, decision making for the indications for and timing of epiphysiodesis is difficult because of unpredictable final discrepancy. The purpose of this study was to analyze longitudinal changes of minor leg-length discrepancy in congenital disorders and to determine earlier predictive values for the clinically significant discrepancy...
October 2015: Orthopedics
João Nunes da Costa, Júlio Matias
No abstract text is available yet for this article.
September 2015: Archives of Plastic Surgery
J Kim, J W Park, S W Hong, J Y Jeong, H S Gong, G H Baek
Macrodactyly of the foot is a rare but disabling condition. We present the results of surgery on 18 feet of 16 patients, who underwent ray amputation and were followed-up for more than two years at a mean of 80 months (25 to 198). We radiologically measured the intermetatarsal width and forefoot area pre-operatively and at six weeks and two years after surgery. We also evaluated the clinical results using the Oxford Ankle Foot Questionnaire for children (OxAFQ-C) and the Questionnaire for Foot Macrodactyly...
October 2015: Bone & Joint Journal
Sudip Kumar Ghosh, Anusree Gangopadhyay
No abstract text is available yet for this article.
November 2015: Journal of Pediatrics
Julia Muellner, Alain Kaelin-Lang, Oliver Pfeiffer, Marwan Mohamed El-Koussy
BACKGROUND: Neurogenic thoracic outlet syndrome is an underestimated cause of brachial weakness and pain. The subclavius posticus muscle (SPM) is an aberrant muscle originating from the medial aspect of the first rib reaching to superior border of the scapula, which may cause, depending on its activation, dynamic compression of the brachial plexus. CASE PRESENTATION: In the present study, we report about a 32-year-old male caucasian patient with weakness in radial deviation of his left hand...
2015: BMC Research Notes
Francisco Javier Downey-Carmona, Araceli Lagares, David Farrington-Rueda, José Lirola-Criado
PURPOSE: We evaluated the result of a combined single-stage surgery in the treatment of first ray macrodactyly in children. INTRODUCTION: Macrodactyly is a rare congenital abnormality that involves thickening of both the soft tissue and bone of the affected digits. It is more frequent in fingers than toes, where there is less neural involvement. Increased growth is also seen in neurofibromatosis, hemangiomatosis, arteriovenous malformations, congenital lymphedema, and syndromes such as Klippel-Trenaunay-Weber syndrome and Proteus syndrome...
August 2015: Journal of Children's Orthopaedics
M Azfar Siddiqui, M Ahmad, N Redhu, I Ahmad, E Ullah
Macrodystrophia lipomatosa is a rare, non-hereditary congenital anomaly characterized by localised gigantism in the form of macrodactyly affecting a part of limb and rarely entire limb due to overgrowth of all mesenchymal elements. Radiological and pathological hallmark is the disproportionate fibroadipose tissue proliferation in subcutaneous tissue, nerve sheaths, and periosteum that lead to soft tissue and bony enlargement. We present the case of a twenty years old female who presented with history of gradual enlargement of the medial aspect of right hand along ulnar nerve distribution since birth...
January 2015: JBR-BTR: Organe de la Société Royale Belge de Radiologie (SRBR)
Yong Chen, Jie Liu, Zekun Zhang, Jianping Ding
OBJECTIVE: To discussion of hand malformations imaging features and clinical classification, tentatively proposed radiological classification. METHODS: A retrospective analysis of the clinical data and image of 101 cases of hands developmental deformity and admitted to hospital affiliated to 1971-2014 years in The Affiliated Hospital of Hangzhou Normal University and the Third Hospital of Hebei Medical University. It is divided into five types base on imaging features: no formation, hypoplasy, over formation, segmental abnormal or joint, bend or abnormal and comparing with classification of Swanson...
May 19, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
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