keyword
MENU ▼
Read by QxMD icon Read
search

synephrine

keyword
https://www.readbyqxmd.com/read/28150474/combined-effects-of-phytochemicals-and-exercise-on-fatty-acid-oxidation
#1
REVIEW
Jong-Hee Kim, Yoonjung Park
Purpose: The purpose of this review is to discuss current views regarding the acute effects of phytochemicals, exercise, and exercise plus phytochemicals on fatty acid oxidation. Methods: Data acquired from human and animal studies were comprehensively assessed to determine the single and combined effects of phytochemicals and exercise on fatty acid oxidation. In addition, underlying mechanisms associated with those conditions that may contribute to the regulation of fat metabolism are discussed...
31, 2016: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/28131938/rapid-analysis-of-aurantii-fructus-immaturus-zhishi-using-paper-spray-ionization-mass-spectrometry
#2
Xuemei Liu, Zhixin Gu, Yuan Guo, Jingjing Liu, Ming Ma, Bo Chen, Liping Wang
Paper spray-mass spectrometry (PS-MS) is a rapid, solvent-efficient, and high-throughput analytical method for analyzing complex samples. In this study, a PS-MS method was developed to obtain MS profiles of Aurantii Fructus Immaturus (aka Zhishi in Chinese) in positive and negative ion modes. In combination with multivariate analyses, including principal component analysis and cluster analysis, the PS-MS profiles of 25 batches of Zhishi were discriminated in 25 batches of Citri Reticulatae Pericarpium Viride (aka Qingpi in Chinese; an adulterant of Zhishi)...
January 22, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28117581/tyramine-pathways-in-citrus-plant-defense-glycoconjugates-of-tyramine-and-its-n-methylated-derivatives
#3
Luigi Servillo, Domenico Castaldo, Alfonso Giovane, Rosario Casale, Nunzia D'Onofrio, Domenico Cautela, Maria Luisa Balestrieri
Glucosylated forms of tyramine and some of its N-methylated derivatives are here reported for the first time to occur in Citrus genus plants. The compounds tyramine-O-β-d-glucoside, N-methyltyramine-O-β-d-glucoside, and N,N-dimethyltyramine-O-β-d-glucoside were detected in juice and leaves of sweet orange, bitter orange, bergamot, citron, lemon, mandarin, and pomelo. The compounds were identified by mass spectrometric analysis, enzymatic synthesis, and comparison with extracts of Stapelia hirsuta L., a plant belonging to the Apocynaceae family in which N,N-dimethyltyramine-O-β-d-glucoside was identified by others...
February 1, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28096758/effects-of-acute-ingestion-of-a-pre-workout-dietary-supplement-with-and-without-p-synephrine-on-resting-energy-expenditure-cognitive-function-and-exercise-performance
#4
Y Peter Jung, Conrad P Earnest, Majid Koozehchian, Elfego Galvan, Ryan Dalton, Dillon Walker, Christopher Rasmussen, Peter S Murano, Mike Greenwood, Richard B Kreider
BACKGROUND: The purpose of this study was to examine the effects of acute ingestion of a pre-workout dietary supplement (PWS) with and without p-synephrine (S) on perceptions of readiness to perform, cognitive function, exercise performance, and markers of safety. METHODS: In a randomized, double-blind, and counterbalanced manner; 25 healthy and recreationally active male and female participants ingested a flavored maltodextrin placebo (PLA), a PWS containing beta-alanine (3 g), creatine nitrate as a salt (2 g), arginine alpha-ketoglutarate (2 g), N-Acetyl-L-Tyrosine (300 mg), caffeine (284 mg), Mucuna pruiriens extract standardized for 15% L-Dopa (15 mg), Vitamin C as Ascorbic Acid (500 mg), niacin (60 mg), folate as folic acid (50 mg), and Vitamin B12 as Methylcobalamin (70 mg) with 2 g of maltodextrin and flavoring; or, the PWS with Citrus aurantium (PWS + S) extract standardized for 30% p-synephrine (20 mg)...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28096757/effects-of-ingesting-a-pre-workout-dietary-supplement-with-and-without-synephrine-for-8%C3%A2-weeks-on-training-adaptations-in-resistance-trained-males
#5
Y Peter Jung, Conrad P Earnest, Majid Koozehchian, Minye Cho, Nick Barringer, Dillon Walker, Christopher Rasmussen, Mike Greenwood, Peter S Murano, Richard B Kreider
BACKGROUND: The purpose of this study was to examine whether ingesting a pre-workout dietary supplement (PWS) with and without synephrine (S) during training affects training responses in resistance-trained males. METHODS: Resistance-trained males (N = 80) were randomly assigned to supplement their diet in a double-blind manner with either a flavored placebo (PLA); a PWS containing beta-alanine (3 g), creatine nitrate as a salt (2 g), arginine alpha-ketoglutarate (2 g), N-Acetyl-L-Tyrosine (300 mg), caffeine (284 mg), Mucuna pruiriens extract standardized for 15% L-Dopa (15 mg), Vitamin C as Ascorbic Acid (500 mg), niacin (60 mg), folate as folic acid (50 mg), and Vitamin B12 as Methylcobalamin (70 mg); or, the PWS supplement with Citrus aurantium extract containing 20 mg of synephrine (PWS + S) once per day for 8-weeks during training...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28058460/-risk-assessment-of-synephrine-in-dietary-supplements
#6
Nadiya Bakhyia, Birgit Dusemund, Klaus Richter, Oliver Lindtner, Karen Ildico Hirsch-Ernst, Bernd Schäfer, Alfonso Lampen
Synephrine is a sympathomimetic phenylethylamine derivative that occurs naturally in citrus fruits. It is often added to dietary supplements intended for weight loss and enhancement of sports performance, typically in the form of Citrus aurantium extracts and in many cases in combination with caffeine. The health risks of synephrine were evaluated on the basis of the available toxicological data and in accordance to the EFSA guidance on the safety assessment of botanicals and botanical preparations intended for use in food supplements...
January 5, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28027941/analysis-of-pharmaceutical-adulterants-in-plant-food-supplements-by-uhplc-ms-ms
#7
Paula Paíga, Manuela J E Rodrigues, Manuela Correia, Joana S Amaral, M Beatriz P P Oliveira, Cristina Delerue-Matos
A method based on the Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) extraction and ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) was successfully developed and validated for the analysis of 26 pharmaceutical compounds belonging to different therapeutic classes (anorexics, stimulants, anxiolytics, antidepressants and laxatives), which are all prone to be illegally added into weight-loss plant food supplements (PFS) for their pharmacological activity...
March 1, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28018234/deciphering-the-function-of-octopaminergic-signaling-on-wing-polyphenism-of-the-pea-aphid-acyrthosiphon-pisum
#8
Xing-Xing Wang, Yi Zhang, Zhan-Feng Zhang, Hong-Gang Tian, Tong-Xian Liu
Aphids exhibit wing polyphenism (winged or wingless) for adaption to predictable or temporally heterogeneous environmental changes; however, the underlying mechanism is still unclear. This morphological change could be stimulated by high aphid density, which in turn could affect octopaminergic signaling in aphids. Octopamine is a neurotransmitter synthesized in insects that can modify their physiological metabolism, locomotion, and other behaviors. We designed experiments to determine whether octopamine functions in wing formation of the pea aphid, Acyrthosiphon pisum (Harris)...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27717489/comparison-of-aurantii-fructus-immaturus-and-aurantii-fructus-based-on-multiple-chromatographic-analysis-and-chemometrics-methods
#9
Pei Li, Su-Ling Zeng, Li Duan, Xiao-Dong Ma, Li-Li Dou, Lan-Jin Wang, Ping Li, Zhi-Ming Bi, E-Hu Liu
To get a better understanding of the bioactive constituents in Aurantii Fructus Immaturus (AFI) and Aurantii Fructus (AF), in the present study, a comprehensive strategy integrating multiple chromatographic analysis and chemometrics methods was firstly proposed. Based on segmental monitoring, a high-performance liquid chromatography (HPLC)-variable wavelength detection method was established for simultaneous quantification of ten major flavonoids, and the quantitative data were further analyzed by hierarchical cluster analysis (HCA) and principal component analysis (PCA)...
October 21, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27484437/the-effects-of-supplementation-with-p-synephrine-alone-and-in-combination-with-caffeine-on-metabolic-lipolytic-and-cardiovascular-responses-during-resistance-exercise
#10
Nicholas A Ratamess, Jill A Bush, Jie Kang, William J Kraemer, Sidney J Stohs, Vincenzo G Nocera, Megan D Leise, Keith B Diamond, Sara C Campbell, Howard B Miller, Avery D Faigenbaum
OBJECTIVE: The purpose of this study was to examine the metabolic, lipolytic, and cardiovascular responses to supplementation with p-synephrine alone and in combination with caffeine during resistance exercise (RE). METHODS: Twelve healthy men performed a control RE protocol (6 × 10 repetitions of squats) and were randomly assigned (using a double-blind crossover design with random protocol sequencing) to a supplement sequence: p-synephrine (S; 100 mg), p-synephrine + caffeine (SCF; 100 mg of p-synephrine plus 100 mg of caffeine), or a placebo (P)...
November 2016: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/27424325/the-emerging-roles-of-human-trace-amines-and-human-trace-amine-associated-receptors-htaars-in-central-nervous-system
#11
REVIEW
Muhammad Zahid Khan, Waqas Nawaz
Human trace amines (TAs) are endogenous compounds, previously almost ignored in human pathology for many reasons (difficulty of their measurement in biological fluids, unknown receptors for elusive amines), are now considered to play a significant role in synaptic transmission within the central nervous system (CNS) acting as neuromodulators. The recent discovery of a novel family of G-protein-coupled receptors (GPCRs) that includes individual members that are highly specific for TAs indicates a potential role for TAs as vertebrate neurotransmitters or neuromodulators, although the majority of these GPCRs so far have not been demonstrated to be activated by TAs...
October 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27280933/a-simple-and-rapid-hplc-pda-ms-method-for-the-profiling-of-citrus-peels-and-traditional-italian-liquors
#12
Clizia Guccione, Maria Camilla Bergonzi, Vieri Piazzini, Anna Rita Bilia
A chromatographic method for the qualitative and quantitative characterization of peels and preparations based on different species of Citrus was developed in order to obtain a complete profile of the constituents, including flavonoids and protoalkaloids. Commercial peels of sweet orange, lemon, mandarin, and grapefruit were analyzed. Seventeen constituents including flavanones, flavones, polymethoxyflavones, and protoalkaloids were identified by HPLC-PDA, HPLC-MS, and HPLC-MS/MS using a comparison of retention times and UV-Vis and MS spectra with reference standards and literature data...
July 2016: Planta Medica
https://www.readbyqxmd.com/read/27038225/acute-p-synephrine-ingestion-increases-fat-oxidation-rate-during-exercise
#13
Jorge Gutiérrez-Hellín, Juan Del Coso
AIMS: p-Synephrine is a protoalkaloid widely used in dietary supplements for weight management because of its purported thermogenic effects. However, there is a lack of scientific information about its effectiveness to increase fat metabolism during exercise. The purpose of this investigation was to determine the effects of an acute ingestion of p-synephrine on fat oxidation at rest and during exercise. METHODS: In a double-blind, randomized and counterbalanced experimental design, 18 healthy subjects performed two acute experimental trials after the ingestion of p-synephrine (3 mg kg(-1) ) or after the ingestion of a placebo (cellulose)...
August 2016: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27009563/abnormal-tyrosine-metabolism-in-chronic-cluster-headache
#14
Giovanni D'Andrea, Massimo Leone, Gennaro Bussone, Paola Di Fiore, Andrea Bolner, Marco Aguggia, Maria Gabriella Saracco, Francesco Perini, Giuseppe Giordano, Antonina Gucciardi, Alberta Leon
Objective Episodic cluster headache is characterized by abnormalities in tyrosine metabolism (i.e. elevated levels of dopamine, tyramine, octopamine and synephrine and low levels of noradrenalin in plasma and platelets.) It is unknown, however, if such biochemical anomalies are present and/or constitute a predisposing factor in chronic cluster headache. To test this hypothesis, we measured the levels of dopamine and noradrenaline together with those of elusive amines, such as tyramine, octopamine and synephrine, in plasma of chronic cluster patients and control individuals...
February 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/26948284/cardiovascular-safety-of-oral-p-synephrine-bitter-orange-in-healthy-subjects-a-randomized-placebo-controlled-cross-over-clinical-trial
#15
Mohd Shara, Sidney J Stohs, Tareq L Mukattash
Bitter orange (Citrus aurantium) extract and its primary protoalkaloid p-synephrine are widely consumed in combination with multiple herbal ingredients for weight management and sports performance. p-Synephrine is also present in juices and foods derived from a variety of Citrus species. Questions exist regarding the safety of p-synephrine because of structural similarities with other biogenic amines. This study assessed the cardiovascular (stimulatory) effects of bitter orange extract (49-mg p-synephrine) given to 18 healthy subjects (nine men and nine women) in a double-blinded, placebo-controlled cross-over study...
May 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/26883936/fast-hepatic-biotransformation-of-p-synephrine-and-p-octopamine-and-implications-for-their-oral-intake
#16
Juliany Fontoura da Silva-Pereira, Gisele Adriana Bubna, Geferson de Almeida Gonçalves, Fabrício Bracht, Rosane Marina Peralta, Adelar Bracht
Citrus aurantium (bitter orange) extracts have been used in products for weight management and sports performance. These extracts contain large amounts of p-synephrine and much smaller amounts of p-octopamine. Both protoalkaloids exert lipolytic and glycogenolytic activities at similar concentrations. The biotransformation of p-synephrine and p-octopamine is not as well-known as those of other adrenergic amines. For this reason transformation of these amines was investigated in the isolated perfused liver. Special attention was devoted to the single pass extraction of each compound as well as to the kinetics of uptake...
March 2016: Food & Function
https://www.readbyqxmd.com/read/26856274/a-review-of-natural-stimulant-and-non-stimulant-thermogenic-agents
#17
REVIEW
Sidney J Stohs, Vladimir Badmaev
Obesity and overweight are major health issues. Exercise and calorie intake control are recognized as the primary mechanisms for addressing excess body weight. Naturally occurring thermogenic plant constituents offer adjunct means for assisting in weight management. The controlling mechanisms for thermogenesis offer many intervention points. Thermogenic agents can act through stimulation of the central nervous system with associated adverse cardiovascular effects and through metabolic mechanisms that are non-stimulatory or a combination thereof...
May 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/26841433/variability-of-stimulant-levels-in-nine-sports-supplements-over-a-9-month-period
#18
Selasi Attipoe, Pieter A Cohen, Amy Eichner, Patricia A Deuster
Many studies have found that some dietary supplement product labels do not accurately reflect the actual ingredients. However, studies have not been performed to determine if ingredients in the same dietary supplement product vary over time. The objective of this study was to assess the consistency of stimulant ingredients in popular sports supplements sold in the United States over a 9-month period. Three samples of nine popular sports supplements were purchased over the 9-month period. The 27 samples were analyzed for caffeine and several other stimulants (including adulterants)...
October 2016: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/26673246/acute-consumption-of-p-synephrine-does-not-enhance-performance-in-sprint-athletes
#19
RANDOMIZED CONTROLLED TRIAL
Jorge Gutiérrez-Hellín, Juan José Salinero, Javier Abían-Vicen, Francisco Areces, Beatriz Lara, Cesar Gallo, Carlos Puente, Juan Del Coso
P-Synephrine is a protoalkaloid widely used as an ergogenic aid in sports. This substance has been included in the World Anti-Doping Agency monitoring program, although scientific information about its effects on performance and athletes' well-being is scarce. The purpose of this investigation was to determine the effectiveness of p-synephrine to increase performance in sprint athletes. In a randomized and counterbalanced order, 13 experienced sprinters performed 2 acute experimental trials after the ingestion of p-synephrine (3 mg·kg(-1)) or after the ingestion of a placebo (control trial)...
January 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/26560757/liquid-chromatographic-determination-of-caffeine-and-adrenergic-stimulants-in-food-supplements-sold-in-brazilian-e-commerce-for-weight-loss-and-physical-fitness
#20
Carine Viana, Gabriela M Zemolin, Larissa S Müller, Thaís R Dal Molin, Helena Seiffert, Leandro M de Carvalho
Methyl-xanthines and adrenergic stimulants, such as caffeine and synephrine, are commonly added to food supplements due to their stimulating and thermogenic effects. In addition, the abusive consumption of food supplements with ergogenic and aesthetic purposes has been observed worldwide. This work describes the study of caffeine, p-synephrine, hordenine, octopamine, tyramine, ephedrine and salicin as stimulants in dietary supplements marketed in Brazil for weight loss and physical fitness claims. A total of 94 different products were acquired from 30 Brazilian websites...
2016: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
keyword
keyword
34991
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"