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Ventricular tachycardia localization

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https://www.readbyqxmd.com/read/29782689/common-and-distinctive-electrocardiographic-characteristics-and-effective-catheter-ablation-of-idiopathic-ventricular-arrhythmias-originating-from-different-areas-of-ventricular-septum-adjacent-to-atrioventricular-annulus
#1
Su-Qin Zhang, Cheng Zheng, Yue-Chun Li, Kang-Ting Ji, Ri-Peng Yin, Jia-Feng Lin, Jia Li
OBJECTIVE: To investigate electrocardiographic (ECG) characteristics and radiofrequency catheter ablation (RFCA) efficacy for premature ventricular complexes (PVCs) and idiopathic ventricular tachycardias (IVTs) originating from ventricular septum areas adjacent to atrioventricular annulus (VS-AVA). METHODS: Among 1505 consecutive PVCs/IVTs cases, 106 (7.04%) were confirmed as origin of VS-AVA guided by both fluoroscopy and three-dimensional mapping system during RFCA...
May 21, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29759537/real-time-localization-of-ventricular-tachycardia-origin-from-the-12-lead-electrocardiogram
#2
John L Sapp, Meir Bar-Tal, Adam J Howes, Jonathan E Toma, Ahmed El-Damaty, James W Warren, Paul J MacInnis, Shijie Zhou, B Milan Horáček
OBJECTIVES: The aim of this study was to develop rapid computational methods for identifying the site of origin of ventricular activation from the 12-lead electrocardiogram. BACKGROUND: Catheter ablation of ventricular tachycardia in patients with structural heart disease frequently relies on a substrate-based approach, which may use pace mapping guided by body-surface electrocardiography to identify culprit exit sites. METHODS: Patients undergoing ablation of scar-related VT (n = 38) had 12-lead electrocardiograms recorded during pacing at left ventricular endocardial sites (n = 1,012) identified on 3-dimensional electroanatomic maps and registered to a generic left ventricular endocardial surface divided into 16 segments and tessellated into 238 triangles; electrocardiographic data were reduced for each lead to 1 variable, consisting of QRS time integral...
July 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759533/12-lead-electrocardiogram-to-localize-region-of-abnormal-electroanatomic-substrate-in-arrhythmogenic-right-ventricular-cardiomyopathy
#3
Cory M Tschabrunn, Haris M Haqqani, Pasquale Santangeli, Erica S Zado, Francis E Marchlinski
OBJECTIVES: The purpose of this study was to evaluate the relationship between electrocardiogram (ECG) QRS fragmentation (fQRS) and right ventricular (RV) endocardial (ENDO) and epicardial (EPI) electroanatomic substrate abnormalities in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). BACKGROUND: fQRS is frequently observed in patients with ARVC and reflects delayed conduction due to RV fibrosis. METHODS: A total of 30 consecutive patients met the task force criteria for ARVC (19 men, mean age 41...
July 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29743411/effects-of-verapamil-and-pinacidil-on-extracellular-k-ph-and-the-incidence-of-ventricular-fibrillation-during-60-minutes-of-ischemia
#4
Ichiro Watanabe, Leonard S Gettes
Ca++ -channel antagonist verapamil and ATP-sensitive K+ -channel opener pinacidil are known to decrease the rise in extracellular K+ ([K+ ]e ) level and pH (pHe ) that occurs during reversible acute myocardial ischemia and to lessen the accompanying activation delay. Verapamil is also known to decrease the incidence of ventricular tachycardia (VT)/fibrillation (VF) during acute myocardial ischemia; however, the effects of ATP-sensitive K+ -channel opener on the incidence of VT/VF are controversial. We studied, in an in vivo pig model, the effects of verapamil and pinacidil on the changes in [K+ ]e level and pHe , local activation, and the incidence of VT/VF during 60 minutes of ischemia...
May 9, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29702740/localization-of-ventricular-activation-origin-using-patient-specific-geometry-preliminary-results
#5
Shijie Zhou, John L Sapp, Amir AbdelWahab, Petr Šťovíček, B Milan Horáček
BACKGROUND AND OBJECTIVES: Catheter ablation of ventricular tachycardia (VT) may include induction of VT and localization of VT-exit site. Our aim was to assess localization performance of a novel statistical pace-mapping method and compare it with performance of an electrocardiographic inverse solution. METHODS: Seven patients undergoing ablation of VT (4 with epicardial, 3 with endocardial exit) aided by electroanatomic mapping underwent intraprocedural 120-lead body-surface potential mapping (BSPM)...
April 27, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29692482/post-procedural-complications-of-cardiac-implants-done-in-a-resource-limited-setting-under-c-arm-a-single-centre-experience
#6
A Jayachandra, Vivek Aggarwal, Sandeep Kumar, I V Nagesh
Background: Cardiology interventions in peripheral hospitals is a challenging task where cardiologist have to fight against time and limited resources. Most of the sudden cardiac deaths occur due to arrhythmia and heart blocks/sinus node dysfunction. Our study is a single peripheral center experience of cardiac devices implantation using a 'C' Arm. The aim of this study was to post procedural complications of cardiac implants done in aresource limited setting under 'C' arm. Methods: This study is done at a peripheral cardiology center with no cardiac catheterization laboratory (CCL) facilities...
April 2018: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/29684187/non-invasive-epicardial-and-endocardial-electrocardiographic-imaging-for-scar-related-ventricular-tachycardia
#7
Linwei Wang, Omar A Gharbia, Saman Nazarian, B Milan Horácek, John L Sapp
Aims: Contact mapping is currently used to guide catheter ablation of scar-related ventricular tachycardia (VT) but usually provides incomplete assessment of 3D re-entry circuits and their arrhythmogenic substrates. This study investigates the feasibility of non-invasive electrocardiographic imaging (ECGi) in mapping scar substrates and re-entry circuits throughout the epicardium and endocardium. Methods and results: Four patients undergoing endocardial and epicardial mapping and ablation of scar-related VT had computed tomography scans and a 120-lead electrocardiograms, which were used to compute patient-specific ventricular epicardial and endocardial unipolar electrograms (CEGMs)...
April 18, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29625195/idiopathic-premature-ventricular-complexes-originating-from-the-distal-great-cardiac-vein-clinical-cardiac-and-electrophysiological-characteristics-and-catheter-ablation-outcome
#8
Wenkui Lv, Xianhui Zhou, Gulinuer Yiming, Ling Zhang, Qina Zhou, Yaodong Li, Qiang Xing, Jianghua Zhang, Yanmei Lu, Hongli Wang, Guiqiu Cao, Baopeng Tang
AIMS: Although catheter ablation for idiopathic ventricular arrhythmia (VA) has been generally well-established, VA originating from the great cardiac vein (GCV) may be clinically challenging due to its epicardial origin, proximity to coronary arteries and limited accessibility. The purpose of this study was to explore its electrophysiological characteristics and identify effective mapping/ablation strategies for idiopathic premature ventricular complexes (PVCs) originating from the GCV...
April 3, 2018: Life Sciences
https://www.readbyqxmd.com/read/29600778/integrated-assessment-of-left-ventricular-electrical-activation-and-myocardial-strain-mapping-in-heart-failure-patients-a-holistic-diagnostic-approach-for-endocardial-cardiac-resynchronization-therapy-ablation-of-ventricular-tachycardia-and-biological-therapy
#9
Francesco Maffessanti, Frits W Prinzen, Giulio Conte, François Regoli, Maria Luce Caputo, Daniel Suerder, Tiziano Moccetti, Francesco Faletra, Rolf Krause, Angelo Auricchio
OBJECTIVES: This study sought to test the accuracy of strain measurements based on anatomo-electromechanical mapping (AEMM) measurements compared with magnetic resonance imaging (MRI) tagging, to evaluate the diagnostic value of AEMM-based strain measurements in the assessment of myocardial viability, and the additional value of AEMM over peak-to-peak local voltages. BACKGROUND: The in vivo identification of viable tissue, evaluation of mechanical contraction, and simultaneous left ventricular activation is currently achieved using multiple complementary techniques...
January 2018: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29582363/electrophysiological-characteristics-and-radiofrequency-ablation-of-sustained-monomorphic-ventricular-tachycardia-in-adult-patients-with-isolated-ventricular-noncompaction
#10
Yanhui Li, Yumei Xue, Jianhua Yu, Chenyang Jiang, Zulu Wang, Mackenzi Mbai, Venkatakrishna Tholakanahalli, David G Benditt, Jian-Ming Li
PURPOSE: This study examined electrophysiological characteristics and outcomes of patients with sustained ventricular tachycardia (VT) in the setting of isolated ventricular noncompaction (IVNC). BACKGROUND: In patients with IVNC, VT has been associated with sudden cardiac death. However, the electrophysiological characteristics and optimal management of these VTs are only incompletely understood. METHODS: This retrospective cohort study assessed arrhythmia characteristics and outcomes in IVNC patients with sustained monomorphic VTs...
March 26, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29581714/congenital-left-ventricular-aneurysms-and-diverticula-an-entity-in-search-of-an-identity
#11
REVIEW
Marc-Alexander Ohlow
Congenital left ventricular aneurysm or diverticulum are rare cardiac malformations described in 809 cases since the first description in 1816, being associated with other cardiac, vascular or thoraco-abdominal abnormalities in about 70%. It appears to be a developmental anomaly, starting in the 4th embryonic week. In an experimental study, targeted knockdown of cardiac troponin T in the chick was performed at day 3, after the heart tube has formed. Morpholino treatment of gene TNNT2 at this stage led to the development of left ventricular diverticula (LVD) in the primitive left ventricular wall...
December 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29572643/novel-mapping-strategies-for-ventricular-tachycardia-ablation
#12
REVIEW
Zaid Aziz, Roderick Tung
Despite advances in antiarrhythmic and device therapy, ventricular tachycardia (VT) continues to be a major cause of increased morbidity and mortality. During scar-mediated monomorphic ventricular tachycardia ablation, the search for critical isthmus sites continues to be the primary goal during successful ablative procedures. However, given the overwhelming hemodynamic instability of most ventricular arrhythmias (> 70%), VT ablation is increasingly performed during sinus rhythm. This technique requires either a greater reliance on isthmus surrogates, or more extensive ablation techniques and is a more probabilistic approach to substrate modification...
March 23, 2018: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29558840/symptoms-of-massive-cardiac-tamponade-during-support-of-biventricular-assist-device
#13
Mosab Al Shakaki, Angelo M Dell'Aquila, Andreas Rukosujew
Typical symptoms of cardiac tamponade are jugular venous distension, pulsus paradoxus, hypotension, and rest dyspnea. However, these clinical symptoms can be masked in patients with ventricular assist device and even more in patients supported with a biventricular-HeartWare ventricular assist device. Hereby, we report the case of a 30-year-old man supported with a biventricular-HeartWare ventricular assist device, who underwent a computed tomography scan due to suspect of ventricular assist device thrombosis...
May 2018: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/29545358/electrocardiographic-repolarization-abnormalities-and-electroanatomic-substrate-in-arrhythmogenic-right-ventricular-cardiomyopathy
#14
Maciej Kubala, Rajeev K Pathak, Shuanglun Xie, Ruben Casado Arroyo, Cory M Tschabrunn, Tatsuya Hayashi, Fermin C Garcia, Gregory E Supple, Pasquale Santangeli, David S Frankel, Erica S Zado, David J Callans, Francis E Marchlinski
BACKGROUND: Repolarization abnormalities in arrhythmogenic right ventricular (RV) cardiomyopathy and their relationship to ventricular tachycardia substrate are incompletely understood. METHODS AND RESULTS: In 40 patients (29 men, mean age 38 years) with arrhythmogenic RV cardiomyopathy, we compared the extent and location of abnormal T (NegT) waves ≥1 mm in depth (n=32) and downsloping elevated ST segment (n=13), in ≥2 adjacent leads, to area and location of endocardial bipolar (<1...
March 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29508083/ablation-approaches-for-ventricular-fibrillation
#15
REVIEW
Prabhpreet Singh, Amit Noheria
Invasive electrophysiology (EP) mapping and catheter ablation has increasingly become the standard of care for many cardiac arrhythmias like supraventricular tachycardias, atrial fibrillation, premature ventricular complexes (PVC), and monomorphic ventricular tachycardia. In this review, we discuss the recent progress made in the mapping and ablation of ventricular fibrillation (VF). Ventricular activation during VF is apparently disorganized, making mapping and interpretation difficult. Prolonged mapping during VF would require mechanical circulatory support as VF causes complete hemodynamic collapse...
March 6, 2018: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29477502/alternans-during-fascicular-ventricular-tachycardia-due-to-digitalis-toxicity
#16
S Serge Barold
This report describes a digitalis-induced regular fascicular ventricular tachycardia characterized by marked QRS alternans a manifestation not usually associated with this arrhythmia. The striking alternation of QRS configuration suggested alternating ventricular activation from either a single focus with two exits in distal branches of the left anterior fascicle or 2 different foci localized in the Purkinje-myocardial network of the left anterior fascicle.
February 8, 2018: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29440186/long-term-outcome-of-substrate-modification-in-ablation-of-post-myocardial-infarction-ventricular-tachycardia
#17
Michael Wolf, Frédéric Sacher, Hubert Cochet, Takeshi Kitamura, Masateru Takigawa, Seigo Yamashita, Konstantinos Vlachos, Ghassen Cheniti, Antonio Frontera, Ruairidh Martin, Nathaniel Thompson, Grégoire Massoullié, Anna Lam, Claire Martin, Florent Collot, Josselin Duchateau, Thomas Pambrun, Arnaud Denis, Nicolas Derval, Mélèze Hocini, Michel Haïssaguerre, Pierre Jaïs
BACKGROUND: Long-term results of substrate modification for ablation of ventricular tachycardia (VT) have not been reported. We report long-term outcomes of substrate elimination targeting local abnormal ventricular activities (LAVA) for post-myocardial infarction VT. METHODS AND RESULTS: One hundred fifty-nine consecutive patients undergoing first ablation were included (65±11 years, 92% implantable cardioverter defibrillators, 54% storms, and 73% appropriate shocks)...
February 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29431260/a-feasibility-study-of-noninvasive-ablation-of-ventricular-tachycardia-using-high-intensity-focused-ultrasound
#18
Fei Lü, Wei Huang, David G Benditt
BACKGROUND: Current transcatheter ablation of ventricular tachycardia (VT) techniques is limited in part by its invasive nature and superficial depth of ablation lesions. OBJECTIVES: This study was aimed at evaluating the feasibility of targeted ablation of cardiac tissues using high-intensity focused ultrasound (HIFU) as a potential means for noninvasive ablation of VT. METHODS: Ablation of ventricular myocardium was performed in anesthetized closed-chest dogs using a HIFU therapeutic system that is currently used clinically for ablation of human solid tumors...
February 12, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29380921/correlation-between-computer-tomography-derived-scar-topography-and-critical-ablation-sites-in-postinfarction-ventricular-tachycardia
#19
Michael Ghannam, Hubert Cochet, Pierre Jais, Maxime Sermesant, Smita Patel, Konstantinos C Siontis, Fred Morady, Frank Bogun
BACKGROUND: Myocardial wall thickness (WT) in patients with a prior myocardial infarction has been used to indicate scarring. However, the correlation of WT with sites critical to ventricular tachycardia (VT) has not been previously investigated. The purpose of this study was to correlate electroanatomic mapping data obtained during VT ablation with WT determined by cardiac computed tomography (CT). METHODS AND RESULTS: Cardiac CTs were performed in 15 consecutive patients (mean age 63 ± 10 years, 86% male, left ventricular ejection fraction 27 ± 12%) with a prior infarct referred for VT ablation...
March 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29356922/point-by-point-versus-multisite-electrode-mapping-in-vt-ablation-does-freedom-from-vt-recurrences-depend-on-mapping-catheter-an-observational-study
#20
Petra Maagh, Arnd Christoph, Markus Sebastian Müller, Henning Dopp, Gunnar Plehn, Axel Meissner
PURPOSE: This study was conducted with the purpose of determining whether or not the potential technical advantages of multi-electrode mapping catheters in catheter ablation (CA) of ventricular tachycardia (VT) result in any relevant clinical benefit for VT patients. METHODS: A single-center VT study, having taken place from 2012 to 2014 using a standard 3.5-mm catheter (Thermocool SF® group 1) and from 2014 to 2016 using a 1-mm multi-electrode-mapping catheter (PentaRay® group 2), was conducted...
March 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
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