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Contact force ablation

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https://www.readbyqxmd.com/read/28543389/coexistence-of-a-permanent-form-of-a-junctional-reciprocating-tachycardia-and-coronary-sinus-aneurysm-a-case-report
#1
Yuki Shimizu, Osamu Inaba, Masahiko Goya, Kenzo Hirao
A 58-year-old man with a long R-P' narrow QRS tachycardia underwent an electrophysiological study. The tachycardia was diagnosed as permanent form of junctional reciprocating tachycardia (PJRT), and the earliest atrial activation site during tachycardia was coronary sinus (CS) ostium. Radiofrequency ablation at the site was initially not successful because the tip impedance and temperature were unstable. After changing of the ablation catheter to that with contact force sensor, the accessory pathway was immediately ablated and the PJRT was no longer induced...
May 24, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28515113/force-sensing-catheters-during-pediatric-radiofrequency-ablation-the-federation-study
#2
Aarti S Dalal, Hoang H Nguyen, Tammy Bowman, George F Van Hare, Jennifer N Avari Silva
BACKGROUND: Based on data from studies of atrial fibrillation ablations, optimal parameters for the TactiCath (TC; St. Jude Medical, Inc) force-sensing ablation catheter are a contact force of 20 g and a force-time integral of 400 g·s for the creation of transmural lesions. We aimed to evaluate TC in pediatric and congenital heart disease patients undergoing ablation. METHODS AND RESULTS: Comprehensive chart and case reviews were performed from June 2015 to March 2016...
May 17, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28513287/contact-force-technology-integrated-with-3d-navigation-system-for-atrial-fibrillation-ablation-improving-results
#3
Roberto Rordorf, Antonio Sanzo, Vincenzo Gionti
Pulmonary veins isolation (PVI) by radiofrequency (RF) ablation is currently an established treatment for symptomatic, drug-resistant paroxysmal atrial fibrillation. Although the effectiveness of the therapy has been clearly demonstrated, success rate after a single procedure is still sub-optimal. The main reason for recurrences after PVI is electrical pulmonary vein-atrium reconnection. In order to increase the likelihood of permanent PVI, the creation of a transmural, durable lesion is mandatory. The main determinants of lesion size and transmurality are power, stability, duration and contact-force during RF application...
May 17, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28468979/increased-lateral-microtubule-contact-at-the-cell-cortex-is-sufficient-to-drive-mammalian-spindle-elongation
#4
Joshua Guild, Miriam B Ginzberg, Christina L Hueschen, Timothy J Mitchison, Sophie Dumont
The spindle is a dynamic structure that changes its architecture and size in response to biochemical and physical cues. For example, a simple physical change, cell confinement, can trigger centrosome separation and increase spindle steady-state length at metaphase. How this occurs is not understood, and is the question we pose here. We find that metaphase and anaphase spindles elongate at the same rate when confined, suggesting that similar elongation forces can be generated independent of biochemical and spindle structural differences...
May 3, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/28455271/evaluation-of-ablation-catheter-technology-comparison-between-thigh-preparation-model-and-an-in%C3%A2-vivo-beating-heart
#5
Eran Leshem, Cory M Tschabrunn, Fernando M Contreras-Valdes, Israel Zilberman, Elad Anter
BACKGROUND: An in vivo animal thigh model is the standard technique for evaluation of ablation catheter technologies, including efficacy and safety of ablation. However, the biophysics of ablation in a thigh model may not be similar to a beating heart. OBJECTIVE: The purpose of this study was to compare efficacy and safety of ablation between a thigh preparation model and a beating heart. METHODS: In 7 swine, radiofrequency ablation using a 3...
April 26, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28451774/relationship-between-left-atrium-catheter-contact-force-and-pacing-threshold
#6
Teresa Barrio-López, Mercedes Ortiz, Eduardo Castellanos, Carla Lázaro, Jefferson Salas, Sergio Madero, Jesús Almendral
PURPOSE: The purpose of this study is to analyze the relationship between contact force (CF) and pacing threshold in left atrium (LA). METHODS: Six to ten LA sites were studied in 28 consecutive patients with atrial fibrillation undergoing pulmonary vein isolation. Median CF, bipolar and unipolar electrogram voltage, impedance, and bipolar and unipolar thresholds for consistent constant capture and for consistent intermittent capture were measured at each site. RESULTS: Pacing threshold measurements were performed at 188 LA sites...
April 27, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28429499/atrial-fibrillation-patients-with-isolated-pulmonary-veins-is-sinus-rhythm-achievable
#7
Judit Szilágyi, Gregory M Marcus, Nitish Badhwar, Byron K Lee, Randall J Lee, Vasanth Vedantham, Zian H Tseng, Tomos Walters, Melvin Scheinman, Jeffrey Olgin, Edward P Gerstenfeld
BACKGROUND: The cornerstone of atrial fibrillation (AF) ablation is isolation of the pulmonary veins (PVs). Patients with recurrent AF undergoing repeat ablation usually have PV reconnection (PVr). The ablation strategy and outcome of patients undergoing repeat ablation who have persistent isolation of all PVs (PVi) at the time of repeat ablation is unknown. METHODS AND RESULTS: We studied consecutive patients with recurrent AF undergoing repeat ablation and compared patients with PVi to those with PVr...
April 21, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28422368/safety-and-efficacy-of-pulmonary-vein-isolation-using-a-surround-flow-catheter-with-contact-force-measurement-capabilities-a-multicenter-registry
#8
Giuseppe Stabile, Paolo Di Donna, Vincenzo Schillaci, Antonio Di Monaco, Assunta Iuliano, Domenico Caponi, Francesco Urraro, Francesco Solimene, Massimo Grimaldi, Marco Scaglione
INTRODUCTION: Pulmonary vein (PV) isolation is the cornerstone of catheter ablation in patients with atrial fibrillation (AF). Surround flow and contact force (CF) measurement capabilities might enhance procedure efficacy and safety. We report on the safety and mid-term efficacy of a novel ablation catheter for PV isolation in patients with AF. METHODS AND RESULTS: Two hundred thirty-three consecutive patients (57±11 years, 76% males, 51% with structural heart disease) referred for paroxysmal (157) or persistent (76) AF, underwent PV isolation by a surround flow catheter with CF measurement capability in 4 centers...
April 19, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28419605/radiofrequency-catheter-ablation-of-atrial-fibrillation-electrical-modification-suggesting-transmurality-is-faster-achieved-with-remote-magnetic-catheter-in-comparison-with-contact-force-use
#9
Sok-Sithikun Bun, Anis Ayari, Decebal Gabriel Latcu, Abdelkarim Errahmouni, Nadir Saoudi
BACKGROUND: Remote magnetic navigation (RMN) and contact force (CF) sensing catheters are available technologies for radiofrequency (RF) catheter ablation of atrial fibrillation (AF). Our purpose was to compare time to electrogram (EGM) modification suggesting transmural lesions between RMN and CF-guided AF ablation. METHODS AND RESULTS: A total of 1,008 RF applications were analyzed in 21 patients undergoing RMN (n = 11) or CF-guided ablation (n = 10) for paroxysmal AF...
April 17, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28416466/risk-of-atrioesophageal-fistula-formation-with-contact-force-sensing-catheters
#10
Eric Black-Maier, Sean D Pokorney, Adam S Barnett, Emily P Zeitler, Albert Y Sun, Kevin P Jackson, Tristram D Bahnson, James P Daubert, Jonathan P Piccini
BACKGROUND: Atrioesophageal fistula formation is a rare but life-threatening complication of atrial fibrillation ablation. Contact force (CF)-sensing catheters improve procedural effectiveness. However, the impact of the implementation of CF-sensing technology on the risk of atrioesophageal fistula formation has not been explored. OBJECTIVE: The purpose of this study was to determine the association between the use of CF-sensing catheters and atrioesophageal fistula development...
April 15, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28381417/determinants-of-acute-and-late-pulmonary-vein-reconnection-in-contact-force-guided-pulmonary-vein-isolation-identifying-the-weakest-link-in-the-ablation-chain
#11
Milad El Haddad, Philippe Taghji, Thomas Phlips, Michael Wolf, Anthony Demolder, Rajin Choudhury, Sébastien Knecht, Yves Vandekerckhove, Rene Tavernier, Hiroshi Nakagawa, Mattias Duytschaever
BACKGROUND: Pulmonary vein reconnection (PVR) still determines recurrences of atrial fibrillation after contact force (CF)-guided pulmonary vein isolation. We studied whether acute PVR (adenosine and waiting time) and late PVR (at repeat) are explained by incomplete transmurality and contiguity within the deployed radiofrequency circle. METHODS AND RESULTS: We analyzed 42 CF-guided ipsilateral pulmonary vein isolation procedures. For each radiofrequency tag within the circle, we collected data reflecting lesion depth (time of application, power, impedance drop [Δ-Imp], CF, force-time integral [FTI], and ablation index [AI]) and contiguity (automated interlesion distance [ILD])...
April 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28260190/general-anesthesia-improves-contact-force-and-reduces-gap-formation-in-pulmonary-vein-isolation-a-comparison-with-conscious-sedation
#12
Akio Chikata, Takeshi Kato, Takanori Yaegashi, Satoru Sakagami, Chieko Kato, Takahiro Saeki, Keiichi Kawai, Shin-Ichiro Takashima, Hisayoshi Murai, Soichiro Usui, Hiroshi Furusho, Shuichi Kaneko, Masayuki Takamura
Compared to conscious sedation (CS), the use of general anesthesia (GA) in pulmonary vein isolation (PVI) is associated with a lower recurrence rate of atrial fibrillation (AF). GA may improve catheter stability and mapping system accuracy compared to CS, but its influence on contact force (CF) parameters during ipsilateral PVI has not previously been investigated. The study population comprised 176 consecutive patients (107 in GA group and 69 in CS group) with AF who underwent their first PVI procedure. We retrospectively assessed CF parameters, force-time integral (FTI), FTI/wall thickness during anatomical ipsilateral PVI and long-term outcome after ablation...
March 4, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28229593/development-of-laser-structured-liquid-infused-titanium-with-strong-biofilm-repellent-properties
#13
Katharina Doll, Elena Fadeeva, Joern Schaeske, Tobias Ehmke, Andreas Winkel, Alexander Heisterkamp, Boris N Chichkov, Meike Stiesch, Nico S Stumpp
Medical implants are commonly used in modern medicine but still harbor the risk of microbial infections caused by bacterial biofilms. As their retrospective treatment is difficult, there is a need for biomedical materials that inhibit bacterial colonization from the start without using antibacterial agents, as these can promote resistance development. The promising concept of slippery liquid-infused porous surfaces (SLIPS) possesses enormous potential for this purpose. In the present study, this principle was applied to titanium, a common material in implantology, and its biofilm-repellent properties were demonstrated...
March 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28215568/reduction-in-radiation-dose-for-atrial-fibrillation-ablation-over-time-a-12-year-single-center-experience-of-2344-patients
#14
Aleksandr Voskoboinik, Elana S Kalman, Yonatan Savicky, Paul B Sparks, Joseph B Morton, Geoffrey Lee, Peter M Kistler, Jonathan M Kalman
BACKGROUND: Pulmonary vein isolation (PVI) is a well-established treatment of atrial fibrillation (AF), with contact force (CF)-sensing catheters joining 3-dimensional mapping systems and image integration as technological advancements over the last decade. OBJECTIVE: The purpose of this study was to analyze trends in radiation exposure for AF ablation over the last 12 years at our center. METHODS: We reviewed prospectively collected data of 2344 consecutive PVI procedures for either paroxysmal or persistent AF between January 2004 and December 2015...
February 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28213499/geometry-and-network-connectivity-govern-the-mechanics-of-stress-fibers
#15
Elena Kassianidou, Christoph A Brand, Ulrich S Schwarz, Sanjay Kumar
Actomyosin stress fibers (SFs) play key roles in driving polarized motility and generating traction forces, yet little is known about how tension borne by an individual SF is governed by SF geometry and its connectivity to other cytoskeletal elements. We now address this question by combining single-cell micropatterning with subcellular laser ablation to probe the mechanics of single, geometrically defined SFs. The retraction length of geometrically isolated SFs after cutting depends strongly on SF length, demonstrating that longer SFs dissipate more energy upon incision...
March 7, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28209944/impact-of-contact-force-technology-on-reducing-the-recurrence-and-major-complications-of-atrial-fibrillation-ablation-a-systematic-review-and-meta-analysis
#16
Xianhui Zhou, Wenkui Lv, Wenhui Zhang, Yuanzheng Ye, Yaodong Li, Qina Zhou, Qiang Xing, Jianghua Zhang, Yanmei Lu, Ling Zhang, Hongli Wang, Wen Qin, Baopeng Tang
Contact force (CF) monitoring can be useful in accomplishing circumferential pulmonary vein (PV) isolation for atrial fibrillation (AF). This meta-analysis aimed to assess the efficacy and safety of a CF-sensing catheter in treating AF. Randomized controlled trials or non-randomized observational studies comparing AF ablation using CF-sensing or standard non-CF (NCF)-sensing catheters were identified from PubMed, EMBASE, Cochrane Library, Wanfang Data, and China National Knowledge Infrastructure (January 1, 1998-2016)...
February 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28190945/mems-based-flexible-force-sensor-for-tri-axial-catheter-contact-force-measurement
#17
Hardik J Pandya, Jun Sheng, Jaydev P Desai
Atrial fibrillation (AFib) is a significant healthcare problem caused by the uneven and rapid discharge of electrical signals from pulmonary veins (PVs). The technique of radiofrequency (RF) ablation can block these abnormal electrical signals by ablating myocardial sleeves inside PVs. Catheter contact force measurement during RF ablation can reduce the rate of AFib recurrence, since it helps to determine effective contact of the catheter with the tissue, thereby resulting in effective power delivery for ablation...
February 2017: Journal of Microelectromechanical Systems
https://www.readbyqxmd.com/read/28185351/persistent-atrial-fibrillation-ablation-with-or-without-contact-force-sensing
#18
Ayman A Hussein, Amr F Barakat, Walid I Saliba, Khaldoun G Tarakji, Mohamed Bassiouny, Bryan Baranowski, Patrick Tchou, Mandeep Bhargava, Thomas Dresing, Thomas Callahan, Daniel Cantillon, Mohamed Kanj, Bruce D Lindsay, Oussama M Wazni
INTRODUCTION: Arrhythmia recurrences remain common after ablation of persistent atrial fibrillation (PersAF). Contact force (CF)-sensing catheters have been introduced for objective assessment of contact during radiofrequency application and have been suggested to improve outcomes in ablation of paroxysmal AF, but little is known about their role in PersAF ablation. We aimed to compare the procedural profiles and outcomes of (PersAF) ablation with or without using CF-sensing catheters...
May 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28150508/is-the-knowledge-of-contact-force-beneficial-in-pulmonary-vein-antrum-isolation
#19
Rune Borregaard, Henrik Kjærulf Jensen, Bawer Jalal Tofig, Samuel Alberg Thrysøe, Christian Gerdes, Jens Cosedis Nielsen, Peter Lukac
OBJECTIVE: To investigate the effect of the operator knowing the real-time contact force (CF) on the efficacy of pulmonary vein antrum isolation (PVAI). METHODS: Fifty patients with paroxysmal atrial fibrillation (AF) or short lasting persistent AF were randomized to CF guided PVAI (n = 25) or conventional PVAI (n = 25). In the CF guided group, CF between 10 and 40 g was aimed at. Efficacy of PVAI was measured as reduction in AF burden (AFB) and time to AF recurrence detected by implantable cardiac monitor (ICM), inserted three months before PVAI...
February 16, 2017: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/28104089/prediction-of-radiofrequency-ablation-lesion-formation-using-a-novel-temperature-sensing-technology-incorporated-in-a-force-sensing-catheter
#20
Guy Rozen, Leon Ptaszek, Israel Zilberman, Kevin Cordaro, E Kevin Heist, Christopher Beeckler, Andres Altmann, Zhang Ying, Zhenjiang Liu, Jeremy N Ruskin, Assaf Govari, Moussa Mansour
BACKGROUND: Real-time radiofrequency (RF) ablation lesion assessment is a major unmet need in cardiac electrophysiology. OBJECTIVE: The purpose of this study was to assess whether improved temperature measurement using a novel thermocoupling (TC) technology combined with information derived from impedance change, contact force (CF) sensing, and catheter orientation allows accurate real-time prediction of ablation lesion formation. METHODS: RF ablation lesions were delivered in the ventricles of 15 swine using a novel externally irrigated-tip catheter containing 6 miniature TC sensors in addition to force sensing technology...
February 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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