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Quadriplegia

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https://www.readbyqxmd.com/read/29123343/multiple-nutritional-deficiencies-in-cerebral-palsy-compounding-physical-and-functional-impairments
#1
P G Hariprasad, K E Elizabeth, Mathew J Valamparampil, D Kalpana, T S Anish
Introduction: Cerebral palsy (CP) refers to a spectrum of disorders causing physical and intellectual morbidity. Macro and micro nutrient deficiencies often contribute to the subnormal physical and mental capabilities of them. Objectives: To assess the growth, nutritional status, physical and functional ability and quality of life in cerebral palsy children and to determine any relation with their gross motor and functional capabilities. Method: The study was conducted at a Tertiary Care Centre, with the participants in the age group 1-16 years...
October 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29117788/recurrent-admissions-for-hypothermia-from-concomitant-topiramate-and-phenobarbital-a-case-report
#2
Alisha M Mutch
INTRODUCTION: This article presents an additional case of concomitant topiramate and phenobarbital administration that resulted in 8 hospital admissions for hypothermia that resolved after discontinuation of phenobarbital. CASE: A 56-year-old white female with cerebral palsy and quadriplegia, epilepsy, and hypothyroidism was admitted to a community teaching hospital multiple times with documented hypothermia. These admissions followed a subsequent dose increase of topiramate in December 2014...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29116382/selective-dorsal-rhizotomy-for-the-treatment-of-severe-spastic-cerebral-palsy-efficacy-and-therapeutic-durability-in-gmfcs-grade-iv-and-v-children
#3
Daniel D'Aquino, Ahmad A Moussa, Amr Ammar, Harshal Ingale, Michael Vloeberghs
BACKGROUND: Selective dorsal rhizotomy (SDR) has been established as an effective surgical treatment for spastic diplegia. The applicability of SDR to the full spectrum of spastic cerebral palsy and the durability of its therapeutic effects remain under investigation. There are currently limited data in the literature regarding efficacy and outcomes following SDR in Gross Motor Function Classification System (GMFCS) IV and V patients. Intrathecal baclofen has traditionally been the surgical treatment of choice for these patients...
November 7, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29082563/magnetic-resonance-imaging-of-the-upper-airway-in-patients-with-quadriplegia-and-obstructive-sleep-apnea
#4
Fergal J O'donoghue, Hailey Meaklim, Lynne Bilston, Alice Hatt, Alan Connelly, Graeme Jackson, Shawna Farquharson, Kate Sutherland, Peter A Cistulli, Douglas J Brown, David J Berlowitz
The aim of this study was to investigate upper airway anatomy in quadriplegics with obstructive sleep apnea. Fifty subjects were recruited from three hospitals in Australia: people with quadriplegia due to spinal cord injury and obstructive sleep apnea (n = 11), able-bodied people with obstructive sleep apnea (n = 18), and healthy, able-bodied controls (n = 19). All underwent 3-Tesla magnetic resonance imaging of their upper airway. A subgroup (n = 34) received a topical vasoconstrictor, phenylephrine and post-phenylephrine magnetic resonance imaging...
October 30, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/29074369/transient-hypokalemic-quadriplegia-following-a-lumbar-transforaminal-epidural-dexamethasone-injection-a-case-report
#5
Maryam Tahmasbi Sohi, William J Sullivan, Dustin J M Anderson
A 30-year-old male with no significant past medical history presented with hypokalemic quadriplegia four hours after he received a lumbar transforaminal epidural steroid injection (TFESI) containing dexamethasone and lidocaine. A comprehensive work up ruled out acquired and hereditary causes of hypokalemic paralysis. Symptoms gradually resolved within hours after potassium restoration with no residual neurologic deficits. Paralysis after TFESI is uncommon, but has been associated with particulate steroids that can coalesce into aggregates and occlude vessels...
October 23, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29021885/fracture-dislocation-at-c6-c7-level-with-quadriplegia-after-traditional-massage-in-a-patient-with-ankylosing-spondylitis-a-case-report
#6
Kak Abilash, Qmq Mohd, Zah Ahmad, Basir Towil
Ankylosing spinal disorders (ASD) tend to result in fractures and/or dislocations after minor trauma because of the altered biomechanical properties. The relative risk of traumatic vertebral fractures in patients with ankylosing spondylitis has been estimated as three times higher than in the general population. These spine traumas, which are located at cervical level in 81% of patients with ankylosing spondylitis, are complicated by neurological lesions in 65% of patients, due to the high inherent instability of these fractures...
July 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/29020869/a-review-of-four-health-procedures-that-school-nurses-may-encounter
#7
Rebecca Toothaker, Pamela Cook
The school nurse plays a vital role in providing care and meeting the health needs of students in the school setting. Students attend school with chronic conditions and complex medical problems such as quadriplegia, cerebral palsy, spina bifida, and muscular dystrophy. It is the responsibility of the school nurse to provide appropriate assessment, early intervention, and care for children in the school environment. The purpose of this article is to review and discuss the knowledge and skills the school nurse needs to care for students with central venous lines, gastrostomy tubes, altered urinary elimination, and tracheostomies...
October 1, 2017: NASN School Nurse
https://www.readbyqxmd.com/read/29017982/clinical-presentation-diagnosis-and-surgical-treatment-of-spontaneous-cervical-intradural-disc-herniations-a-review-of-the-literature
#8
REVIEW
Arunprasad Gunasekaran, Nova Kristine M de Los Reyes, Jerry Walters, Noojan Kazemi
OBJECTIVE: Spontaneous cervical intradural disc herniation (IDH) is a rare occurrence with limited and disparate information available regarding its presentation, diagnosis, and treatment. However, its accurate detection is vital for planning surgical treatment. In this review of the literature, we collected data from all cervical intradural disc herniations described to date. Particular attention is paid to diagnostic findings, surgical approach and causation for cervical IDH, especially at the cervicothoracic junction...
October 7, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28990647/-medullar-thoracic-compression-by-tophaceous-gout-presentation-of-a-case-and-review-of-the-literature
#9
(no author information available yet)
INTRODUCTION: Spine involvement in gout is an extremely uncommon complication. Dorsalgia and quadriplegia are some manifestations that may occur, although these symptoms are seen more frequently in other more prevalent pathologies, such as spinal tumors. CASE REPORT: We present an unusual case of thoracic spinal cord compression at T10-T11 level caused by the extradural deposit of tophaceous material in a 52-year-old woman with uncontrolled chronic tophaceous gout...
October 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28983951/development-of-a-cerebral-palsy-follow-up-registry-in-jordan-cpup-jordan
#10
N A Almasri, M Saleh, S Abu-Dahab, S H Malkawi, E Nordmark
AIMS: This study aims to describe the development of a Cerebral Palsy Follow-up Registry in Jordan (CPUP-Jordan) and to provide a baseline child and parent demographic information, birth history of the child participants, and distribution of the participants based on topographical distribution of cerebral palsy (CP) and functional classification systems. METHODS: The CPUP-Jordan was developed using a similar framework of a follow-up surveillance programme for persons with CP in Sweden (CPUP)...
October 6, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28973395/tubb4a-mutations-result-in-specific-neuronal-and-oligodendrocytic-defects-that-closely-match-clinically-distinct-phenotypes
#11
Julian Curiel, Guillermo Rodríguez Bey, Asako Takanohashi, Marianna Bugiani, Xiaoqin Fu, Nicole I Wolf, Bruce Nmezi, Raphael Schiffmann, Mona Bugaighis, Tyler Pierson, Guy Helman, Cas Simons, Marjo S van der Knaap, Judy Liu, Quasar Padiath, Adeline Vanderver
Hypomyelinating leukodystrophies are heritable disorders defined by lack of development of brain myelin, but the cellular mechanisms of hypomyelination are often poorly understood. Mutations in TUBB4A, encoding the tubulin isoform tubulin beta class IVA (Tubb4a), result in the symptom complex of hypomyelination with atrophy of basal ganglia and cerebellum (H-ABC). Additionally, TUBB4A mutations are known to result in a broad phenotypic spectrum, ranging from primary dystonia (DYT4), isolated hypomyelination with spastic quadriplegia, and an infantile onset encephalopathy, suggesting multiple cell types may be involved...
November 15, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28953517/acute-onset-quadriplegia-with-recovery-after-high-voltage-electrical-injury
#12
Daniel Delgadillo, Stephanie Chapman, Matthew P Fahrenkopf, Matthew D Martin
Although uncommon, electrical injuries are associated with significant morbidity and mortality. There have been several reports of neurological sequelae secondary to electrical injury; however, the neurophysiology is still not completely understood. These neurological complications pose the greatest risk for permanent disability. We present a case of acute-onset quadriplegia after high-voltage electrical injury without radiographic evidence. Two months after the injury, the patient went on to regain partial sensorimotor function...
November 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28948076/peripheral-neuropathy-in-limbic-encephalitis-with-anti-glutamate-receptor-antibodies-case-report-and-systematic-literature-review
#13
Yi-Chia Wei, Chin-Chang Huang, Chi-Hung Liu, Hung-Chou Kuo, Jainn-Jim Lin
INTRODUCTION: Autoantibodies to the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor and N-methyl-d-aspartate (NMDA) receptor are known to be the causes of autoimmune encephalitis particularly limbic encephalitis. The involvement of the peripheral nervous system is rarely reported. METHODS: We analyzed the serial nerve conduction studies of a previously reported case of anti-AMPA receptor encephalitis, who was presented with conscious disturbance and quadriplegia...
September 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28940391/cervical-and-middle-dorsal-actinomycetomas-from-guerrero-state-mexico
#14
Guadalupe E Estrada-Chávez, Roberto Estrada, Ramon Fernandez, Roberto Arenas, Alain Reyes, Cindy Guevara, Guadalupe Chávez-López
BACKGROUND: Mycetomas are frequent subcutaneous mycoses with typical clinical characteristics such as sinuses, blood-stained, serous, or purulent exudates as well as local swelling. Even though the most commonly affected areas are the lower limbs, we report four cases affecting the neck and midback regions, of which three were young females. We draw attention to the importance of early identification of these cases for prevention and specific treatment in order to avoid severe consequences or irreversible complications such as quadriplegia...
November 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28879705/guillain-barre-syndrome-induced-by-heat-stroke-a-case-report-and-literature-review
#15
Huijun Wen
BACKGROUND: Heat stroke is a potentially fatal condition that is caused by elevated core temperature. GuillainBarre syndrome (GBS) induced by heat stroke is extremely rare, and its manifestation with damage to multiple cranial nerves has not been described. METHODS: We describe a rare case of GBS induced by heat stroke with damage to multiple cranial and peripheral nerves. The clinical, radiological, and electrophysiological profiles were presented and analyzed...
September 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28867317/extensive-mirror-image-neurofibromas-of-entire-spine-resulting-in-spastic-tetraplegia
#16
Mark Bigder, Paul Szelemej, Neil Berrington
Neurofibromatosis 1 (NF1) is associated with increased incidence of spinal tumors including neurofibromas. The majority of NF1-associated spine neurofibromas are asymptomatic; however, a minority of patients will experience neurologic symptoms that can range from mild paresthesia, radiculopathy, myelopathy, and focal weakness to quadriplegia in extreme cases. We present a 21-year-old male diagnosed with NF1 in infancy and followed for multiple mirror-image neurofibromas involving the entire spine. He was asymptomatic until age 14 when he developed neck pain and progressive tetraplegia with magnetic resonance imaging showing severe cord compression secondary to bilateral C2 neurofibromas...
September 1, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28839319/spinal-cord-injury-without-radiographic-abnormality-sciwora-in-adults-a-report-of-two-cases
#17
Adil Aziz Khan, Shafaq Mahmood, Tayyaba Saif, Aleesha Gul
Spinal cord injury without any radiographic abnormality (SCIWORA) is rare in adults. We describe here two case reports of adult patients, who presented to us with quadriplegia, following a road traffic accident. Plain radiography and computed tomography (CT) of cervical spine were normal. Hence the patients were diagnosed as cases of adult SCIWORA. However, subsequent magnetic resonance imaging (MRI) of the two patients revealed cervical cord injury in the form of cord contusion and disc protrusion, respectively...
August 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28831620/a-rabies-virus-vampire-bat-variant-shows-increased-neuroinvasiveness-in-mice-when-compared-to-a-carnivore-variant
#18
COMPARATIVE STUDY
Leonardo Pereira Mesquita, Thais Helena Martins Gamon, Silvia Elena Campusano Cuevas, Karen Miyuki Asano, Willian de Oliveira Fahl, Keila Iamamoto, Karin Correa Scheffer, Samira Maria Achkar, Dennis Albert Zanatto, Cláudia Madalena Cabrera Mori, Paulo César Maiorka, Enio Mori
Rabies is one of the most important zoonotic diseases and is caused by several rabies virus (RABV) variants. These variants can exhibit differences in neurovirulence, and few studies have attempted to evaluate the neuroinvasiveness of variants derived from vampire bats and wild carnivores. The aim of this study was to evaluate the neuropathogenesis of infection with two Brazilian RABV street variants (variant 3 and crab-eating fox) in mice. BALB/c mice were inoculated with RABV through the footpad, with the 50% mouse lethal dose (LD50) determined by intracranial inoculation...
December 2017: Archives of Virology
https://www.readbyqxmd.com/read/28825856/the-use-of-variant-maps-to-explore-domain-specific-mutations-of-fgfr1
#19
L A Lansdon, H V Bernabe, N Nidey, J Standley, M J Schnieders, J C Murray
Here we describe the genotype-phenotype correlations of diseases caused by variants in Fibroblast Growth Factor Receptor 1 ( FGFR1) and report a novel, de novo variant in FGFR1 in an individual with multiple congenital anomalies. The proband presented with bilateral cleft lip and palate, malformed auricles, and bilateral ectrodactyly of his hands and feet at birth. He was later diagnosed with diabetes insipidus, spastic quadriplegia, developmental delay, agenesis of the corpus callosum, and enlargement of the third cerebral ventricle...
October 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28762473/late-diagnosis-and-atypical-brain-imaging-of-aicardi-gouti%C3%A3-res-syndrome-are-we-failing-to-diagnose-aicardi-gouti%C3%A3-res-syndrome-2
#20
Leah Svingen, Mitchell Goheen, Rena Godfrey, Colleen Wahl, Eva H Baker, William A Gahl, May Christine V Malicdan, Camilo Toro
Aicardi-Goutières syndrome (AGS) is a rare disorder with in utero or postnatal onset of encephalopathy and progressive neurological deterioration. The seven genetic subtypes of AGS are associated with abnormal type I interferon-mediated innate immune response. Most patients with AGS present with progressive microcephaly, spasticity, and cognitive impairment. Some, especially those with type 2 (AGS2), manifest milder phenotypes, reduced childhood mortality, and relative preservation of physical and cognitive abilities...
December 2017: Developmental Medicine and Child Neurology
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