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https://www.readbyqxmd.com/read/28545533/food-beliefs-and-practices-among-the-kalenjin-pregnant-women-in-rural-uasin-gishu-county-kenya
#1
Roselyter Monchari Riang'a, Jacqueline Broerse, Anne Kisaka Nangulu
BACKGROUND: Understanding food beliefs and practices is critical to the development of dietary recommendations, nutritional programmes, and educational messages. This study aimed to understand the pregnancy food beliefs and practices and the underlying reasons for these among the contemporary rural Kalenjin communities of Uasin Gishu County, Kenya. METHODS: Through semi-structured interviews, data was collected from 154 pregnant and post-natal Kalenjin women about restricted and recommended foods, and why they are restricted or recommended during pregnancy...
May 25, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28544427/advanced-consumable-free-morphological-analysis-of-intact-red-blood-cells-by-a-compact-scanning-flow-cytometer
#2
K V Gilev, E S Yastrebova, D I Strokotov, M A Yurkin, N A Karmadonova, A V Chernyshev, V V Lomivorotov, V P Maltsev
Whereas modern automated blood cell analyzers measure the volume of individual red blood cells (RBCs), leading to four RBC indices (mean corpuscular volume, MCV; mean corpuscular hemoglobin, MCH; mean corpuscular hemoglobin concentration, MCHC; red cell distribution width, and RDW), the RBC shape has not been assessed by clinical screening tools. We applied the scanning flow cytometer (SFC) for complete characterization of intact RBC morphology in terms of diameter, maximal and minimal thicknesses, volume, surface area, sphericity index, spontaneous curvature, hemoglobin concentration, and content...
May 19, 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/28535315/early-career-outcomes-of-family-medicine-residency-graduates-exposed-to-innovative-flexible-longitudinal-tracks
#3
Richard A Young, Dan Casey, Diana Singer, Elaine Waller, Patricia A Carney
BACKGROUND AND OBJECTIVES: The Preparing the Personal Physician for Practice (P4) project used a case series design to study innovations in the content, length, structure, and location of residency training in 14 geographically diverse family medicine programs between 2007 and 2012. We aimed to explore how offering flexible longitudinal tracks (FLT) affected graduates' scope of practice, particularly in maternal child health (MCH), which included at least 17 months of focused training that increased each year over 4 years...
May 2017: Family Medicine
https://www.readbyqxmd.com/read/28527391/melanin-concentrating-hormone-and-sleep
#4
REVIEW
Jozelia Gomes Pacheco Ferreira, Jackson Cioni Bittencourt, Antoine Adamantidis
The melanin-concentrating hormone (MCH) is an essential neuromodulator involved with homeostatic regulation and motivated behaviors. The majority of MCH neurons are localized within the zona incerta, lateral hypothalamic and incerto-hypothalamic areas but others regions, as the olfactory turbecle, the laterodorsal tegmental nucleus, the paramediam pontine reticular formation and the medial preoptic area, can also express the peptide depending on the gender and metabolic state of the animal. If the MCH on these novel sites of expression are also related with the control of wake-sleep cycle will be discuss in this review...
May 17, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/28526553/hypothalamic-regulation-of-the-sleep-wake-cycle
#5
REVIEW
Daisuke Ono, Akihiro Yamanaka
Sleep is one of the most important physiological functions in mammals. It is regulated by not only homeostatic regulation but also circadian clock. Several neuropeptide-producing neurons located in the hypothalamus are implicated in the regulation of sleep/wakefulness. Among them, orexin/hypocretin-producing neurons (orexin neurons) are a crucial component for maintenance of wakefulness, because lack of orexin function results in narcolepsy, which is a sleep disorder. Recent findings have identified substances that excite or inhibit neural activity of orexin neurons...
May 16, 2017: Neuroscience Research
https://www.readbyqxmd.com/read/28523045/frequency-of-nutritional-anemia-among-female-medical-students-of-faisalabad
#6
Shireen Jawed, Sundus Tariq, Saba Tariq, Anwar Kamal
BACKGROUND AND OBJECTIVE: Anemia is a common health problem worldwide. This problem is most commonly faced by 18 to 25 years of females. Medical students especially female hostelites poses high risk of anemia because of their poor eating habits, breakfast skipping, long schedule in college, burden of medical studies, clinical postings, and extra-curricular activities. Therefore the current study was designed to determine the hemoglobin status in young female medical students. We also elucidate its association with BMI...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28481447/solvent-geometry-regulated-cooperative-supramolecular-polymerization
#7
Suhrit Ghosh
This article discloses H-bonding driven supramolecular polymerization of a core-substituted naphthalene-diimide derivative NDI-1 which exhibits J-aggregation in all tested hydrocarbon solvents however spontaneous gelation was noticed only in linear alkanes in contrast to free flowing solution in their cyclic analogues. Mechanistic investigation by variable temperature UV/Vis studies and analyzing the data using an appropriate model(s) elucidate a highly cooperative self-assembly pathway in linear hydrocarbons (heptane, octane, nonane or decane) in sharp contrast to cyclohexane or methyl-cyclohexane in which an ill-defined polymerization was noticed...
May 8, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28462634/effectiveness-of-the-maternal-and-child-health-handbook-in-burundi-for-increasing-notification-of-birth-at-health-facilities-and-postnatal-care-uptake
#8
Kayo Kaneko, Jacques Niyonkuru, Ndereye Juma, Térence Mbonabuca, Keiko Osaki, Atsuko Aoyama
BACKGROUND: In Burundi, birth certificate ownership (56.4%) and postnatal care (PNC) coverage (30%) remain low. Birth certificates prove birth registration and allow clients to receive free medical care including PNC. To obtain birth certificates, notification of birth by witnesses is indispensable. However, use of existing parallel home-based records for mother and child has prevented clients from successfully receiving notification of birth and related information. OBJECTIVE: To assess the effectiveness of the Maternal and Child Health (MCH) handbook for increasing notification of birth at health facilities and PNC uptake...
2017: Global Health Action
https://www.readbyqxmd.com/read/28446301/-analysis-of-gene-mutation-types-of-thalassemia-in-longyan-area-of-fujian-province-in-china
#9
Qing-Fu Dai, Xiao-Lu Li, Yu-Xia Wang, Chun-Fang Cao
OBJECTIVE: To explore the type and distribution of thalassemia gene mutation in Longyan area of Fujian province in China, so as to provide a evidence for prenatal diagnosis and to reduce birth defects. METHODS: The mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and hemoglobin electrophoresis were used for screened the mutation types of thalassemia. Genotyping of the screened positive sample was performed by gap single polymerase chain reaction (gap-PCR) and reverse dot blot hybridization (RDB)...
April 2017: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/28446232/continuous-quality-improvement-interventions-to-improve-long-term-outcomes-of-antiretroviral-therapy-in-women-who-initiated-therapy-during-pregnancy-or-breastfeeding-in-the-democratic-republic-of-congo-design-of-an-open-label-parallel-group-randomized-trial
#10
Marcel Yotebieng, Frieda Behets, Bienvenu Kawende, Noro Lantoniaina Rosa Ravelomanana, Martine Tabala, Emile W Okitolonda
BACKGROUND: Despite the rapid adoption of the World Health Organization's 2013 guidelines, children continue to be infected with HIV perinatally because of sub-optimal adherence to the continuum of HIV care in maternal and child health (MCH) clinics. To achieve the UNAIDS goal of eliminating mother-to-child HIV transmission, multiple, adaptive interventions need to be implemented to improve adherence to the HIV continuum. METHODS: The aim of this open label, parallel, group randomized trial is to evaluate the effectiveness of Continuous Quality Improvement (CQI) interventions implemented at facility and health district levels to improve retention in care and virological suppression through 24 months postpartum among pregnant and breastfeeding women receiving ART in MCH clinics in Kinshasa, Democratic Republic of Congo...
April 26, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28427008/lateral-hypothalamic-circuits-for-sleep-wake-control
#11
REVIEW
Takayuki Yamashita, Akihiro Yamanaka
The lateral hypothalamic area (LHA) of the diencephalon is crucially involved in controlling instinctive behavior such as sleep-wake cycle and feeding behavior. LHA is a heterogeneous structure that contains spatially intermingled, genetically distinct cell populations. Among LHA neurons, orexin/hypocretin (OX) neuron is the key cell type that promotes waking, and specific loss of OX neurons results in narcolepsy. Melanin-concentrating hormone (MCH) containing neurons are known to be active during rapid eye movement (REM) sleep and stimulation of these neurons promotes REM sleep...
April 17, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/28424562/immunological-and-hematological-reference-intervals-among-hiv-seronegative-pregnant-women-in-northwest-ethiopia
#12
Meaza Genetu, Debasu Damtie, Meseret Workineh, Biniam Mathewos Tebeje, Bamlaku Enawgaw, Tekalign Deressa
BACKGROUND: Pregnancy is a state characterized by profound physiological hematological changes. However, hematological reference intervals being used in clinical practice in Ethiopia are derived from nonlocal general populations, despite the significant variations reported previously. The aim of this study was to determine the immunological and hematological reference intervals in healthy pregnancy among HIV-seronegative pregnant women in northwest Ethiopia. MATERIALS AND METHODS: A total of 200 healthy, HIV-seronegative pregnant women were enrolled from February 2015 to June 2015 in a cross-sectional study setting at Gondar University Hospital...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28421900/the-magnitude-and-factors-related-to-facility-based-maternal-mortality-in-mozambique
#13
Leonardo Chavane, Martinho Dgedge, Olivier Degomme, Osvaldo Loquiha, Marc Aerts, Marleen Temmerman
Facility-based maternal mortality remains an important public health problem in Mozambique. A number of factors associated with health system functioning can be described behind the occurrence of these deaths. This paper aimed to evaluate the magnitude of the health facility-based maternal mortality, its geographical distribution and to assess the health facility factors implicated in the occurrence of these deaths. A secondary analysis was done on data from the survey on maternal health needs performed by the Ministry of Health of Mozambique in 2008...
May 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28413893/the-hb-e-hbb-c-79g-a-mean-corpuscular-volume-mean-corpuscular-hemoglobin-cutoff-points-in-double-heterozygous-hb-e-sea-%C3%AE-thalassemia-1-carriers-are-dependent-on-hemoglobin-levels
#14
Prapapun Leckngam, Ektong Limweeraprajak, Tiemjan Kiewkarnkha, Thanusak Tatu
Identifying double heterozygosities in Hb E (HBB: c.79 G>A)/- -(SEA) (Southeast Asian) (α-thalassemia-1) (α-thal-1) in patients first diagnosed as carrying Hb E is important in thalassemia control. Low Hb E, mean corpuscular volume (MCV) and mean corpuscular hemoglobin (Hb) (MCH) levels have been observed in this double heterozygosity. However, the cutoff points of these parameters have never been systematically established. Here, we analyzed Hb E and red blood cell (RBC) parameters in 372 Hb E patients grouped by Hb levels, by the status of - -(SEA) and -α(3...
April 16, 2017: Hemoglobin
https://www.readbyqxmd.com/read/28395547/a-novel-mutation-of-the-%C3%AE-2-globin-gene-causing-%C3%AE-thalassemia-hb-nanning-hba2-c-369_370delinsga
#15
Biyan Chen, Li Lin, Shang Yi, Qiuli Chen, Hongwei Wei, Guojian Li, Chenguang Zheng, Sheng He, XiaoXia Qiu
We report a novel mutation on the α2-globin gene, Hb Nanning (HBA2:c.369_370delinsGA) detected in a Chinese family. This mutation gives rise to a previously undescribed hemoglobin (Hb) variant that was undetectable by various separation techniques. Both carriers of the mutation have mean corpuscular volume (MCV) and mean corpuscular Hb (MCH) values that are below normal, as would be predicted for an α(+)-thalassemia (α(+)-thal) patient.
April 11, 2017: Hemoglobin
https://www.readbyqxmd.com/read/28391514/inflammatory-and-oxidative-stress-markers-in-experimental-allergic-asthma
#16
Renata Tiscoski Nesi, Emanuel Kennedy-Feitosa, Manuella Lanzetti, Mariana Barcellos Ávila, Clarissa Bichara Magalhães, Walter Araújo Zin, Débora Souza Faffe, Luís Cristóvão Porto, Samuel Santos Valença
Ovalbumin-induced allergic lung inflammation (ALI) is a condition believed to be mediated by cytokines, extracellular matrix remodeling, and redox imbalance. In this study, we evaluated pulmonary function together with inflammatory markers as interleukin-4 (IL-4), myeloperoxidase (MPO), eosinophil cells, and redox markers in the lungs of BALB/c mice after ovalbumin (OVA) sensitization and challenge. Our results showed an increase in bronchial hyperresponsiveness stimulated by methacholine (Mch), inflammatory cell influx, especially eosinophils together with an increase of high mobility group box 1 (HMGB1) and altered lipid peroxidation (LP) and antioxidant defenses in the OVA group compared to the control group (p ≤ 0...
April 8, 2017: Inflammation
https://www.readbyqxmd.com/read/28391052/bio-orthogonal-conjugation-and-enzymatically-triggered-release-of-proteins-within-multi-layered-hydrogels
#17
Chen Guo, Heejae Kim, Elisa M Ovadia, Christine M Mourafetis, Mingrui Yang, Wilfred Chen, April M Kloxin
Hydrogels are facile architectures for the controlled presentation of proteins with far-reaching applications, from fundamental biological studies in three-dimensional culture to new regenerative medicine and therapeutic delivery strategies. Here, we demonstrate a versatile approach for spatially-defined presentation of engineered proteins within hydrogels through i) immobilization using bio-orthogonal strain-promoted alkyne-azide click chemistry and ii) dynamic protease-driven protein release using exogenously applied enzyme...
April 5, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28388354/haemoglobin-oxygen-saturation-leucocyte-count-and-lactate-dehydrogenase-are-predictors-of-elevated-cerebral-blood-flow-velocity-in-nigerian-children-with-sickle-cell-anaemia
#18
Oyesola Oyewole Ojewunmi, Titilope Adenike Adeyemo, Akinniyi Adediran Osuntoki, Ngozi Awa Imaga, Ajoke Idayat Oyetunji
BACKGROUND: Transcranial Doppler ultrasound (TCD) scan, which measures blood flow velocity through the time-averaged mean of maximum velocities (TAMMVs) in the internal carotid arteries and middle cerebral arteries, is a useful screening tool for predicting stroke risk in children with sickle cell anaemia (SCA). AIM: To investigate which clinical and laboratory indices predict abnormal TCD velocity in children with SCA. METHODS: Fifty-four SCA patients with normal TCD (TAMMV < 170 cm/s), classified as negative TCD (NTCD), and 93 patients with conditional and abnormal TCD velocities (TAMMV ≥ 170 cm/s) classified as positive TCD were recruited...
April 7, 2017: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/28386910/iron-deficiency-and-red-cell-indices-in-patients-with-heart-failure
#19
Michał Tkaczyszyn, Josep Comín-Colet, Adriaan A Voors, Dirk J van Veldhuisen, Cristina Enjuanes, Pedro Moliner-Borja, Piotr Rozentryt, Lech Poloński, Waldemar Banasiak, Piotr Ponikowski, Peter van der Meer, Ewa A Jankowska
AIMS: To investigate the prevalence of iron deficiency (ID) in heart failure (HF) patients with normal vs. abnormal red cell indices (RCI), the associations between iron parameters and RCI, and prognostic consequences of ID independently of RCI. METHODS AND RESULTS: We analysed clinical data of 1821 patients with HF [mean age 66 ± 13 years; 71% men; New York Heart Association class I/II/III/IV (11%/39%/44%/6%); left ventricular ejection fraction >45%: 19%]. Iron deficiency (ferritin <100 µg/L or ferritin 100-299 µg/L with transferrin saturation <20%) was common irrespective of the presence of anaemia (haemoglobin <12 g/dL in women and <13 g/dL in men) or low RCI, from 75% in anaemic subjects with low mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), and MCH concentration (MCHC), to 36% in non-anaemic subjects with MCV, MCH, and MCHC above the lower limit of normal...
April 6, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28383095/dentists-perception-of-primary-health-care-services-in-family-health-and-mother-and-child-health-clinics-in-alexandria-egypt
#20
Maha El Tantawi, Maha A El-Din Hamza, Marwa M Sabry
This study compared dentists' perceptions of provided services in Family Health (FH) and Mother and Child Health (MCH) clinics. A questionnaire was distributed to 120 dentists in 7 FH and 4 MCH clinics in Alexandria, Egypt in 2012. The questionnaire assessed personal and professional background, perceptions of primary health care (PHC) role, types of services provided, patient recall and referral systems and perception of service quality. The response rate was 100%. More FH dentists perceived their role to include providing care for children and pregnant women...
March 30, 2017: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
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