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https://www.readbyqxmd.com/read/29777929/substituent-effect-on-the-acid-induced-isomerization-of-spiropyran-compounds
#1
Lixia Cui, Honghong Zhang, Guomei Zhang, Ying Zhou, Li Fan, Lihong Shi, Caihong Zhang, Shaomin Shuang, Chuan Dong
Spiropyran compounds are well known as an isomeric system, the closed spiropyran (SP) could be converted into the open merocyanine (MC) via acid-induced because stable protonated merocyanine (MCH) were formed by combination of MC and H+ . In order to understand how the substituent affect the isomerization of spiropyran. A series of the chromene 7-subsituted spiropyran compounds were designed and synthesized. The photophysical properties of them were studied comparatively by UV-absorption and fluorescence spectra in different pH...
May 16, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29774328/solvent-dependent-pathway-complexity-and-seeded-supramolecular-polymerization
#2
Goutam Ghosh, Suhrit Ghosh
cNDI-1 exhibits an off-pathway aggregate in cyclic hydrocarbon (MCH) but produces a helical supramolecular polymer in linear alkane (decane) by well-defined J-aggregation. Effective solvent-assisted nucleation in linear alkanes due to shape matching with the peripheral alkyl chains of a monomer is responsible for the pathway complexity. Seed, produced by sonication induced fragmentation of the fibers in decane, could initiate supramolecular polymerization of the off-pathway aggregate in MCH generating controllable helical nanostructures...
May 18, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29774145/evaluation-of-attenuative-effect-of-tert-butylhydroquinone-against-diazinon-induced-oxidative-stress-on-hematological-indices-in-male-wistar-rats
#3
Saman Sargazi, Hamidreza Galavi, Sadegh Zarei
Diazinon is an organophosphate toxicant that has been identified to induce oxidative stress within biological systems through altering biochemical and hematological indices, by generating free radicals while deteriorating the cellular antioxidant defense system. The present study was designed to evaluate the effectiveness of tert-butylhydroquinone (TBHQ), a synthetic food additive, in serving as an antioxidant against sub-lethal diazinon-induced oxidative stress in male Wistar rats. Animals were randomly divided into 4 groups: Control (treated with corn oil as a vehicle), diazinon (10 mg/kg/day), TBHQ (0...
June 2018: Biomedical Reports
https://www.readbyqxmd.com/read/29752840/hematological-and-immunological-reference-intervals-for-adult-population-in-the-state-of-amhara-ethiopia
#4
Bamlaku Enawgaw, Wubet Birhan, Molla Abebe, Betelihem Terefe, Habtamu Wondifraw Baynes, Tekalign Deressa, Mulugeta Melku
OBJECTIVE: Reference intervals (RIs) currently being used in Ethiopia are derived from western populations. Thus, this study aimed to establish locally derived hematological and immunological RIs. METHOD: The study was conducted in Amhara State, Ethiopia with a total of 967 (55.2% males) participants. 56.9% of males and 43.1% of females were eligible for hematological and immunological RI determination. A non-parametric test was used for the determination of upper (97...
May 12, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29747641/the-syrian-conflict-a-case-study-of-the-challenges-and-acute-need-for-medical-humanitarian-operations-for-women-and-children-internally-displaced-persons
#5
Rahma Aburas, Amina Najeeb, Laila Baageel, Tim K Mackey
BACKGROUND: After 7 years of increasing conflict and violence, the Syrian civil war now constitutes the largest displacement crisis in the world, with more than 6 million people who have been internally displaced. Among this already-vulnerable population group, women and children face significant challenges associated with lack of adequate access to maternal and child health (MCH) services, threatening their lives along with their immediate and long-term health outcomes. DISCUSSION: While several health and humanitarian aid organizations are working to improve the health and welfare of internally displaced Syrian women and children, there is an immediate need for local medical humanitarian interventions...
May 11, 2018: BMC Medicine
https://www.readbyqxmd.com/read/29744286/adolescent-pregnancy-and-challenges-in-kenyan-context-perspectives-from-multiple-community-stakeholders
#6
Manasi Kumar, Keng-Yen Huang, Caleb Othieno, Dalton Wamalwa, Beatrice Madeghe, Judith Osok, Simon Njuguna Kahonge, Joyce Nato, Mary McKernon McKay
Objective: The key objective of this paper is to provide a phenomenological account of the mental health challenges and experiences of adolescent new mothers. We explore the role of social support and the absence of empathy plays in depression among pregnant adolescents. The project also collected data on the adolescents' caregiving environment which includes the adolescents' mothers, their partners, the community, and health care workers, as well as feedback from staff nurses at the maternal and child health centers...
March 2018: Global Social Welfare: Research, Policy & Practice
https://www.readbyqxmd.com/read/29736076/a-study-on-association-of-iron-deficiency-with-attention-deficit-hyperactivity-disorder-in-a-tertiary-care-center
#7
Kamirul Islam, Soutrik Seth, Suman Saha, Atanu Roy, Rajib Das, Asok Kumar Datta
Background: Iron is important for brain development and cognitive function. Iron deficiency may cause alteration of neurotransmitters and may be manifested by different central nervous system disorders including attention deficit hyperactivity disorder (ADHD). Aims: As studies are scarce in the Indian context, we had undertaken this study to find out the association between iron deficiency and ADHD. Settings and Design: Hospital-based cross-sectional study...
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29722905/influence-of-biological-factors-on-hematological-and-serum-biochemistry-values-in-captive-ad%C3%A3-lie-chinstrap-gentoo-and-macaroni-penguins-in-pingtung-taiwan
#8
Shih-Yu Chen, Yi-Lun Tsai, Suen-Chuain Lin, Yeong-Huey Wu, Ming-Huei Liao, Ching-Dong Chang, Tsung-Hsien Li, Hsiao-Kuang Ho
Hematology and serum biochemistry reference values are essential for health evaluation and disease diagnosis in penguins. However, there are currently no published physiological values for captive Adélie (Pygoscelis adeliae) and Chinstrap penguins (P. antarcticus), nor for wild or captive Macaroni penguins (Eudyptes chrysolophus). The present study is the first investigation regarding hematology and serum biochemistry reference values for captive Adélie, Gentoo (P. papua), Chinstrap, and Macaroni penguins in Asia...
May 3, 2018: Zoo Biology
https://www.readbyqxmd.com/read/29722520/microbubble-triggered-spontaneous-separation-of-transparent-thin-films-from-substrates-using-evaporable-core-shell-nanocapsules
#9
Intae Son, Byungsun Lee, Jae Hong Kim, Chunho Kim, Ji Yong Yoo, Byung Wook Ahn, Jeongho Hwang, Jonghyuk Lee, Jun Hyup Lee
The spontaneous separation of a polymer thin film from a substrate is an innovative technology that will enable material recycling and reduce manufacturing cost in the film industry, and this can be applied in a wide range of applications, from optical films to wearable devices. Here, we present an unprecedented spontaneous strategy for separating transparent polymer films from substrates on the basis of micro-bubble generation using nanocapsules containing an evaporable material. The core-shell nanocapsules are prepared from poly(methyl methacrylate)-polyethyleneimine nanoparticles via the encapsulation of methylcyclohexane (MCH)...
May 3, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29716882/vacuolization-in-myeloid-and-erythroid-precursors-in-a-child-with-menkes-disease
#10
Seçil Sayın, Şule Ünal, Mualla Cetin, Fatma Gumruk
A five year-old boy, who was under follow-up with a clinical and biochemical diagnosis of Menkes Disease (MD) since ten months of age, was admitted with diarrhea. On examination he had a characteristic cherubic face hypopigmented, sparse hair, hepatosplenomegaly, hypotonia with brisk deep tendon reflexes. Hemogram revealed: Hb:5.5g/dL, Hct:16.2%, RBC:1.69x1012/L, MCV:95.8fL, MCH:32.3pg, RDW:19.2%, WBC:2.2x109/L and platelet count;157x109/L. Serum vitamin B12 level was 575pg/mL. Serum copper level was 81μg/dL and serum zinc level was 152μg/dL...
April 30, 2018: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/29714060/a-review-of-single-nucleotide-polymorphisms-snps-in-orexigenic-neuropeptides-targeting-g-protein-coupled-receptors-gpcrs
#11
Mark D Ericson, Carrie Haskell-Luevano
Many physiological pathways are involved in appetite, food intake, and the maintenance of energy homeostasis. In particular, neuropeptides within the central nervous system have been demonstrated to be critical signaling molecules for modulating appetite. Both anorexigenic (appetite-decreasing) and orexigenic (appetite-stimulating) neuropeptides have been described. The biological effects of these neuropeptides can be observed following central administration in animal models. This review will focus on single nucleotide polymorphisms (SNPs) in six orexigenic neuropeptides: agouti-related protein (AGRP), galanin, melanin concentrating hormone (MCH), neuropeptide Y (NPY), orexin A, and orexin B...
May 1, 2018: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29713509/the-momconnect-helpdesk-how-an-interactive-mobile-messaging-programme-is-used-by-mothers-in-south-africa
#12
REVIEW
Khou Xiong, Joy Kamunyori, Jane Sebidi
South Africa's MomConnect mobile messaging programme, which aims to promote safe motherhood and improve pregnancy outcomes for South African women, includes a helpdesk feature which allows women registered on the system to ask maternal and child health (MCH)-related questions and to provide feedback on health services received at public health clinics. Messages sent to the helpdesk are answered by staff located at the National Department of Health. We examined event data from the MomConnect helpdesk database to identify any patterns in messages received, such as correlation of frequency or types of messages with location...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29708054/comparison-of-nasa-tlx-scale-modified-cooper-harper-scale-and-mean-inter-beat-interval-as-measures-of-pilot-mental-workload-during-simulated-flight-tasks
#13
Heikki Mansikka, Kai Virtanen, Don Harris
The sensitivity of NASA-TLX scale, modified Cooper-Harper (MCH) scale and the mean inter-beat interval (IBI) of successive heart beats, as measures of pilot mental workload (MWL), were evaluated in a flight training device (FTD). Operational F/A-18C pilots flew instrument approaches with varying task loads. Pilots' performance, subjective MWL ratings and IBI were measured. Based on the pilots' performance, three performance categories were formed; high-, medium- and low-performance. Values of the subjective rating scales and IBI were compared between categories...
April 30, 2018: Ergonomics
https://www.readbyqxmd.com/read/29703996/knockdown-of-hypocretin-attenuates-extended-access-of-cocaine-self-administration-in-rats
#14
Brooke E Schmeichel, Alessandra Matzeu, Pascale Koebel, Leandro F Vendruscolo, Harpreet Sidhu, Roxana Shahryari, Brigitte L Kieffer, George F Koob, Rémi Martin-Fardon, Candice Contet
The hypocretin/orexin (HCRT) neuropeptide system regulates feeding, arousal state, stress responses, and reward, especially under conditions of enhanced motivational relevance. In particular, HCRT neurotransmission facilitates drug-seeking behavior in circumstances that demand increased effort and/or motivation to take the drug. The present study used a shRNA-encoding adeno-associated viral vector to knockdown Hcrt expression throughout the dorsal hypothalamus in adult rats and determine the role of HCRT in cocaine self-administration...
April 6, 2018: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29702578/parental-translation-into-practice-of-healthy-eating-and-active-play-messages-and-the-impact-on-childhood-obesity-a-mixed-methods-study
#15
Alyssa Huxtable, Lynne Millar, Penelope Love, Colin Bell, Jill Whelan
Childhood obesity is a significant health issue worldwide. Modifiable risk factors in early childhood relate to child healthy eating and active play, and are influenced by parents. The aim of the study was two-fold. Firstly, to determine the weight status of children aged between birth and 3.5 years in a rural and remote area of Australia. Secondly, to explore the relationship between child weight status and translation of advice on healthy eating and active play provided to parents by local, nurse-led, Maternal Child Health (MCH) services...
April 27, 2018: Nutrients
https://www.readbyqxmd.com/read/29702310/endoscopic-anterior-approach-for-cervical-disc-disease-disc-preserving-surgery
#16
Vijay Singh Parihar, Nishtha Yadav, Shailendra Ratre, MCh Amitesh Dubey, Yad Ram Yadav
BACKGROUND: Anterior endoscopic techniques in cervical disc were found to be effective and safe. We report our experience of 210 patients of endoscopic disc removal by anterior approach which is largest series for management of cervical myelopathy. METHODS: Visual analogue scale (VAS) and Nurick grading system was used to assess severity of neck and arm pain and functional outcomes respectively. Myelopathy (with or without unilateral or bilateral radiculopathy), or the unilateral radiculopathy having either soft or hard disc prolapsed were included...
April 24, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29695301/health-in-yemen-losing-ground-in-war-time
#17
Charbel El Bcheraoui, Aisha O Jumaan, Michael L Collison, Farah Daoud, Ali H Mokdad
BACKGROUND: The effect of the ongoing war in Yemen on maternal and child health (MCH) has not been comprehensively assessed. Providing a situational analysis at the governorate level is critical to assist in planning a response and allocating resources. METHODS: We used multiple national- and governorate-level data sources to provide estimates of 12 relevant MCH indicators in 2016 around child vaccination, and child and maternal nutritional status, and the change in these estimates for the period 2013-2016 based on shock variables including change in gross domestic product, burden of airstrikes per 1000 population, change in access to untreated water sources and unimproved toilets, and change in wheat flour prices...
April 25, 2018: Globalization and Health
https://www.readbyqxmd.com/read/29692590/hemolysis-area-a-new-parameter-of-erythrocyte-osmotic-fragility-for-screening-of-thalassemia-trait
#18
Thanusak Tatu, Denis Sweatman
BACKGROUND: One-tube osmotic fragility test (OFT) is widely used for screening thalassemia traits. Interobserver variation may occur with 0.36% NaCl-based OFT due to the naked eye result reading style. PURPOSE: The purpose of this study was to establish and evaluate the novel numerical OFT-based parameter, so-called hemolysis area (HA), in screening thalassemia traits. MATERIALS AND METHODS: The portable spectrophotometer was invented capable of calculating the HA values...
April 2018: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/29680268/distribution-of-mch-containing-fibers-in-the-feline-brainstem-relevance-for-rem-sleep-regulation
#19
Alicia Costa, Santiago Castro-Zaballa, Patricia Lagos, Michael H Chase, Pablo Torterolo
Neurons that utilize melanin-concentrating hormone (MCH) as a neuromodulator are localized in the postero-lateral hypothalamus and incerto-hypothalamic area. These neurons project diffusely throughout the central nervous system and have been implicated in critical physiological processes, such as sleep. Unlike rodents, in the order carnivora as well as in humans, MCH exerts its biological functions through two receptors: MCHR-1 and MCHR-2. Hence, the cat is an optimal animal to model MCHergic functions in humans...
April 19, 2018: Peptides
https://www.readbyqxmd.com/read/29663165/inhibitory-effects-of-semiochemicals-on-the-attraction-of-an-ambrosia-beetle-euwallacea-nr-fornicatus-to-quercivorol
#20
John A Byers, Yonatan Maoz, David Wakarchuk, Daniela Fefer, Anat Levi Zada
The Euwallacea fornicatus (Eichhoff) species complex includes the polyphagous shot hole borer (PSHB), an ambrosia beetle infesting avocado limbs, Persea americana Mill. Synthetic quercivorol, a monoterpene alcohol, is known to attract females (males are flightless) over a range of release rates spanning three orders of magnitude. The upper release dose was extended 10-fold using sticky traps baited with quercivorol released at 1× (0.126 mg/day), 10×, and 108× relative rates to obtain a dose-response curve fitting a kinetic formation function...
April 17, 2018: Journal of Chemical Ecology
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