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https://www.readbyqxmd.com/read/28930166/environmental-influences-on-maternal-and-child-health
#1
EDITORIAL
Katherine P Theall, Carolyn C Johnson
This Special Issue of IJERPH focuses on maternal and child health (MCH), with research that highlights the role of environmental influences on MCH across a range of settings.[...].
September 20, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28925418/mhealth-application-areas-and-technology-combinations-a-comparison-of-literature-from-high-and-low-middle-income-countries
#2
Haitham Abaza, Michael Marschollek
BACKGROUND: With the continuous and enormous spread of mobile technologies, mHealth has evolved as a new subfield of eHealth. While eHealth is broadly focused on information and communication technologies, mHealth seeks to explore more into mobile devices and wireless communication. Since mobile phone penetration has exceeded other infrastructure in low and middle-income countries (LMICs), mHealth is seen as a promising component to provide pervasive and patient-centered care. OBJECTIVES: The aim of our research work for this paper is to examine the mHealth literature to identify application areas, target diseases, and mHealth service and technology types that are most appropriate for LMICs...
August 8, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28917529/bronchoprotective-effect-of-deep-inspirations-in-cough-variant-asthma-a-distinguishing-feature-in-the-spectrum-of-airway-disease
#3
Nastasia Wasilewski, Thomas Fisher, Scott E Turcotte, John T Fisher, M Diane Lougheed
PURPOSE: To assess the effect of deep inspirations (DIs) on airway behaviour in individuals with classic asthma (CA), cough variant asthma (CVA), and methacholine (MCh)-induced cough but normal airway sensitivity (COUGH) during bronchoprovocation. METHODS: Twenty-five adults (18 female; 44.8±12.3years (Mean±SD); n=9 CA, n=9 CVA, and n=7 COUGH) completed two single-dose MCh challenges, with and without DIs. Bronchoprotection was assessed by comparing changes in bronchoconstriction (FEV1, FVC, FEV1/FVC, FEF50, FEF25-75), gas trapping (RV, RV/TLC) and impulse oscillometry (IOS) measurements...
September 13, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28899777/jerusalem-artichoke-enriched-diet-on-growth-performance-immuno-hematological-changes-and-disease-resistance-against-aeromonas-hydrophila-in-asian-seabass-lates-calcarifer
#4
Sajjad Syed Raffic Ali, Kondusamy Ambasankar, Mohamed Saiyad Musthafa, Ramasamy Harikrishnan
A 45 days feeding trial was conducted to study the effect of Jerusalem artichoke (JA) on growth performance, body composition, biochemical, immuno-hematological parameters and disease resistance in Asian seabass (Lates calcarifer) fingerlings against Aeromonas hydrophila. JA was supplemented at three different levels viz., control 0, 5, 10, and 20 g kg(-1) in the commercial diet (403 g kg(-1)protein and 89 g kg (-1)lipid) in L. calcarifer. The results showed that there were no significant (P > 0...
September 9, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28894993/effect-of-growth-hormone-overexpression-on-gastric-evacuation-rate-in-coho-salmon
#5
Jin-Hyoung Kim, Satid Chatchaiphan, Michelle T Crown, Samantha L White, Robert H Devlin
Growth hormone (GH) transgenic (T) coho salmon consistently show remarkably enhanced growth associated with increased appetite and food consumption compared to non-transgenic wild-type (NT) coho salmon. To improve understanding of the mechanism by which GH overexpression mediates food intake and digestion in T fish, feed intake and gastric evacuation rate (over 7 days) were measured in size-matched T and NT coho salmon. T fish displayed greatly enhanced feed intake levels (~ 2.5-fold), and more than 3-fold increase in gastric evacuation rates relative to NT coho salmon...
September 11, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/28893267/is-the-role-of-health-extension-workers-in-the-delivery-of-maternal-and-child-health-care-services-a-significant-attribute-the-case-of-dale-district-southern-ethiopia
#6
Abel Negussie, Gedion Girma
BACKGROUND: The Health Extension Program (HEP) is one of the most innovative community based health program launched by the Ethiopian Federal Ministry of Health to make health services accessible to rural communities by setting-out women Health Extension Workers (HEWs) in rural Health Posts. The HEWs are premised to provide basic, largely preventive, primary health services to rural villages and the program gives special attention to children and mothers. The objective of the study was to assess the contribution made by the Health Extension Workers in maternal and child health care service delivery in Dale district, southern Ethiopia...
September 11, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28893214/a-mixed-methods-study-on-evaluating-the-performance-of-a-multi-strategy-national-health-program-to-reduce-maternal-and-child-health-disparities-in-haryana-india
#7
Madhu Gupta, Hans Bosma, Federica Angeli, Manmeet Kaur, Venkatesan Chakrapani, Monica Rana, Onno C P van Schayck
BACKGROUND: A multi pronged community based strategy, known as National Rural Health Mission (NRHM), was implemented from 2005-06 to 2012-13 in India to curtail maternal and child health (MCH) disparities between poor and rich, rural and urban areas, and boys and girls,. This study aimed to determine the degree to which MCH plans of NRHM implemented, and resulted in improving the MCH outcomes and reducing the inequalities. METHODS: An explanatory sequential mixed methods study was conducted, first to assess the degree of implementation of MCH plans by estimating the budget utilization rates of each MCH plan, and the effectiveness of these plans by comparing demographic health surveys data conducted post (2012-13), during (2007-08) and pre- (2002-04) NRHM implementation period, in the quantitative study...
September 11, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28892906/changes-in-haematological-parameters-in-newborns-born-to-preeclamptic-mothers-a-case-control-study-in-a-rural-hospital
#8
Kalavakuru Mouna, Shilpa Manigatta Doddagowda, Krishnappa Junjegowda, Latha Krishnamurthy
INTRODUCTION: Pregnancy is a physiological phenomenon. However, some women develop problems during pregnancy period, which puts both the mother's and the foetus health at risk. Hypertensive disorders of pregnancy are the type of the maternal diseases that can cause the most detrimental effects to the mother and foetus. AIMS: To determine the haematological parameters in neonates born to preeclamptic mothers. MATERIALS AND METHODS: It was a prospective case control study carried out on neonates born to preeclamptic mothers in our institute from March 2016 to November 2016...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28890402/lung-responses-in-murine-models-of-experimental-asthma-value-of-house-dust-mite-over-ovalbumin-sensitization
#9
Camille Doras, Ferenc Petak, Sam Bayat, Aurélie Baudat, Christophe Von Garnier, Philippe Eigenmann, Walid Habre
Ovalbumin (OVA) sensitization has limitations in modelling asthma. Thus, we examined the value of allergic sensitization using a purified natural allergen, house dust mite (HDM), over the sensitization performed with OVA. Mice were sham-treated, or sensitized with OVA- or HDM with identical chronology. Airway resistance, tissue damping and elastance were assessed under control conditions and after challenging the animals with methacholine (MCh) and the specific allergen. Inflammatory profile of the bronchoalveolar lavage fluid was characterized and lung histology was performed...
September 8, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28888943/melanin-concentrating-hormone-modulates-oxytocin-mediated-marble-burying
#10
Nayna M Sanathara, Celia Garau, Amal Alachkar, Lien Wang, Zhiwei Wang, Katsuhiko Nishimori, Xiangmin Xu, Olivier Civelli
Repetitive and perseverative behaviors are common features of a number of neuropsychiatric diseases such as Angelman's syndrome, Tourette's syndrome, obsessive-compulsive disorder, and autism spectrum disorders. The oxytocin system has been linked to the regulation of repetitive behavior in both animal models and humans, but many of its downstream targets have still to be found. We report that the melanin-concentrating hormone (MCH) system is a target of the oxytocin system in regulating one repetitive behavior, marble burying...
September 6, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28870237/the-n-and-c-terminal-carbohydrate-recognition-domains-of-haemonchus-contortus-galectin-bind-to-distinct-receptors-of-goat-pbmc-and-contribute-differently-to-its-immunomodulatory-functions-in-host-parasite-interactions
#11
MingMin Lu, XiaoWei Tian, XinChao Yang, Cheng Yuan, Muhammad Ehsan, XinChao Liu, RuoFeng Yan, LiXin Xu, XiaoKai Song, XiangRui Li
BACKGROUND: Hco-gal-m is a tandem-repeat galectin isolated from the adult worm of Haemonchus contortus. A growing body of studies have demonstrated that Hco-gal-m could exert its immunomodulatory effects on host peripheral blood mononuclear cells (PBMC) to facilitate the immune evasion. Our previous work revealed that C-terminal and N-terminal carbohydrate recognition domains (CRD) of Hco-gal-m had different sugar binding abilities. However, whether different domains of Hco-gal-m account differently for its multiple immunomodulatory functions in the host-parasite interaction remains to be elucidated...
September 5, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28867197/litter-size-determines-the-number-of-melanin-concentrating-hormone-neurons-in-the-medial-preoptic-area-of-sprague-dawley-lactating-dams
#12
Jozelia Gomes Pacheco Ferreira, Jessica Catharine Gomes Duarte, Giovanne Baroni Diniz, Jackson Cioni Bittencourt
Melanin-concentrating hormone [MCH] is an important neuromodulator related to motivated behaviors. The MCH-containing neurons are mainly located in the lateral hypothalamic area, zona incerta, and incerto-hypothalamic area. In the medial preoptic area [MPOA], a key region for the regulation of maternal behavior, Pmch mRNA expression and MCH synthesis can be detected exclusively during the lactation period. As litter size affects different parameters of maternal physiology, the aim of this study was to verify whether litter size can modulate the number of MCH-containing neurons in the MPOA of lactating rats...
September 1, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28865214/serum-amyloid-a-protein-saa-haptoglobin-hp-and-selected-hematological-and-biochemical-parameters-in-wild-mares-before-and-after-parturition
#13
L Krakowski, P Bartoszek, I Krakowska, P Olcha, T Piech, A Stachurska, P Brodzki
The aim of the study was to evaluate physiological changes in hematological and biochemical parameters in mares in perinatal period. Blood samples were collected from 24 pregnant Polish Konik breed mares which were divided into two groups. The first group (Group - I, n=12) comprised mares living in the wild, in the reserve. The second group (Group - II, n=12) consisted of mares kept in stables. The blood was collected 2 weeks prior to the parturition, then 24 hours after the delivery, and then at the 7th and 21st day after foaling...
March 1, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28862436/induced-dipole-directed-cooperative-self-assembly-of-a-benzotrithiophene
#14
Toshiaki Ikeda, Hiroaki Adachi, Hiroyuki Fueno, Kazuyoshi Tanaka, Takeharu Haino
A benzotrithiophene derivative possessing phenylisoxazoles self-assembled to form stacks. The molecule isodesmically self-assembled in chloroform, whereas it self-assembled in a cooperative fashion in decalin and in methylcyclohexane. Thermodynamic studies based on isodesmic, van der Schoot, and Goldstein-Stryer mathematical models revealed that the self-assembly processes are enthalpically driven and entropically opposed. An enthalpy-entropy compensation plot indicates that the assembly processes in chloroform, decalin, and methylcyclohexane are closely related...
September 1, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28858406/chemogenetic-activation-of-the-lateral-hypothalamus-reverses-early-life-stress-induced-deficits-in-motivational-drive
#15
Erin J Campbell, Caitlin S Mitchell, Cameron D Adams, Jiann Wei Yeoh, Deborah M Hodgson, Brett A Graham, Christopher V Dayas
Altered motivated behaviour is a cardinal feature of several neuropsychiatric conditions including mood disorders. One well-characterized antecedent to the development of mood disorders is exposure to early life stress (ELS). A key brain substrate controlling motivated behaviour is the lateral hypothalamus (LH). Here we examined the effect of ELS on LH activation and the motivation to self-administer sucrose. We tested whether chemogenetic activation of LH circuits could modify sucrose responding in ELS rats and examined the impact on LH cell populations...
August 31, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28853915/rgs4-overexpression-in-lung-attenuates-airway-hyper-responsiveness-in-mice
#16
Laura A Madigan, Gordon S Wong, Elizabeth M Gordon, Wei-Sheng Chen, Nariman Balenga, Cynthia J Koziol-White, Reynold A Panettieri, Stewart J Levine, Kirk M Druey
A cardinal feature of asthma is airway hyper-responsiveness (AHR) to spasmogens, many of which activate G protein-coupled receptors (GPCRs) on airway smooth muscle (ASM) cells. Asthma subtypes associated with allergy are characterized by eosinophilic inflammation in the lung due to the type 2 immune response to allergens and proinflammatory mediators that promote AHR. The degree to which intrinsic abnormalities of ASM contribute to this phenotype remains unknown. The Regulators of G protein signaling (RGS proteins) are a large group of intracellular proteins that inhibit GPCR signaling pathways...
August 30, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28852810/label-free-peptide-aptamer-based-impedimetric-biosensor-for-highly-sensitive-detection-of-tnt-with-a-ternary-assembly-layer
#17
Yanyan Li, Manru Zhao, Haiyan Wang
We report a label-free peptide aptamer based biosensor for highly sensitive detection of TNT which was designed with a ternary assembly layer consisting of anti-TNT peptide aptamer (peptamer), dithiothreitol (DTT), and 6-mercaptohexanol (MCH), forming Au/peptamer-DTT/MCH. A linear relationship between the change in electron transfer resistance and the logarithm of the TNT concentration from 0.44 to 18.92 pM, with a detection limit of 0.15 pM, was obtained. In comparison, the detection limit of the aptasensor with a common binary assembly layer (Au/peptamer/MCH) was 0...
August 29, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28842217/cytoskeleton-related-regulation-of-primary-cilia-shortening-mediated-by-melanin-concentrating-hormone-receptor-1
#18
Sakura Tomoshige, Yuki Kobayashi, Kosuke Hosoba, Akie Hamamoto, Tatsuo Miyamoto, Yumiko Saito
Primary cilia are specialized microtubule-based organelles. Their importance is highlighted by the gamut of ciliary diseases associated with various syndromes including diabetes and obesity. Primary cilia serve as signaling hubs through selective interactions with ion channels and conventional G-protein-coupled receptors (GPCRs). Melanin-concentrating hormone (MCH) receptor 1 (MCHR1), a key regulator of feeding, is selectively expressed in neuronal primary cilia in distinct regions of the mouse brain. We previously found that MCH acts on ciliary MCHR1 and induces cilia shortening through a Gi/o-dependent Akt pathway with no cell cycle progression...
August 22, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28839103/levosimendan-prevents-bronchoconstriction-and-adverse-respiratory-tissue-mechanical-changes-in-rabbits
#19
Barna Babik, Adam Laszlo Balogh, Roberta Sudy, Orsolya Ivankovitsne-Kiss, Gergely H Fodor, Ferenc Petak
Levosimendan has a calcium-sensitizing effect in the myocardium and opens adenosine-triphosphate-sensitive potassium channels (KATP) in vascular smooth muscle. Since airway smooth muscle also expresses KATP, we characterized the protective potential of levosimendan against increased airway and respiratory tissue resistances. Animals were administered levosimendan alone (Group L), levosimendan after pretreatment with a KATP channel blocker (glibenclamide, Group LG), glibenclamide only (Group G), or solvent alone (dextrose, Group C)...
August 24, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28831229/baseline-hematology-and-serum-biochemistry-results-for-indian-leopards-panthera-pardus-fusca
#20
Arun Attur Shanmugam, Sanath Krishna Muliya, Ajay Deshmukh, Sujay Suresh, Anukul Nath, Pa Kalaignan, Manjunath Venkataravanappa, Lyju Jose
AIM: The aim of the study was to establish the baseline hematology and serum biochemistry values for Indian leopards (Panthera pardus fusca), and to assess the possible variations in these parameters based on age and gender. MATERIALS AND METHODS: Hemato-biochemical test reports from a total of 83 healthy leopards, carried out as part of routine health evaluation in Bannerghatta Biological Park and Manikdoh Leopard Rescue Center, were used to establish baseline hematology and serum biochemistry parameters for the subspecies...
July 2017: Veterinary World
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