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JOURNAL ARTICLE
Chao Long Azad, Nicholas A Orlando, Allan J Belzberg, Sami H Tuffaha
Improving upper extremity function in high cervical spinal cord injury (SCI) patients with tetraplegia is a challenging task owing to the limited expendable donor muscles and nerves that are available. Restoring active wrist extension for these patients is critical because it allows for tenodesis grasp. This is classically achieved with brachioradialis (BR) to extensor carpi radialis brevis (ECRB) tendon transfer, but outcomes are suboptimal because BR excursion is insufficient and its origin proximal to the elbow further limits the functionality of the tendon transfer, particularly in the absence of elbow extension...
February 27, 2024: Techniques in Hand & Upper Extremity Surgery
#22
Mohamed Emile Dembélé, Abdoulaye Yalcouyé, Mamadou Cissoko, Lassana Cissé, Cheick Oumar Guinto, Guida Landouré
Sporadic thyrotoxic periodic paralysis (TPP) is a rare muscle disorder that manifests with abrupt muscle weakness and hypokalemia associated with hyperthyroidism. It is mostly reported in the Asian population, and rare in Caucasians. Only few cases have been reported in people with black ancestry. Here, we report a rare case of thyrotoxic periodic paralysis revealing Graves' disease in a young Malian. A 17-year-old man was admitted in the Neurology clinic with rapid proximal tetraplegia that started after strenuous physical activities at the school...
February 2024: Clinical Case Reports
#23
Jordi Recuero-Borau, Laura Masfarré, Nil Navarro, Pedro Rocha, Álvaro Taus, Edurne Arriola
BACKGROUND: Lung cancer is one of the tumor types with highest incidence of thromboembolic events (TE), especially adenocarcinoma subtype. ROS1 rearrangements confer higher risk of TE. Non-bacterial thrombotic endocarditis (NBTE) is a rare event, frequently diagnosed on autopsy. Clinical suspicion is key to reach the diagnosis and start early treatment of the underlying cause and anticoagulation in order to improve patients' outcomes. CASE DESCRIPTION: Here we present two cases of NBTE in patients with ROS1 -rearranged lung cancer with different clinical debuts...
January 31, 2024: Translational Lung Cancer Research
#24
JOURNAL ARTICLE
Junghwan Park, Dong Gyu Lee
A 65-year-old with a history of spinal cord injury and previous cervical surgery presented with persistent fever despite antibiotic treatment. MRI scans revealed an abscess in the neck extending from C3 to C6, with associated osteomyelitis. After an initial discharge following antibiotic therapy, the patient was readmitted due to recurrent systemic infection symptoms and another abscess. A subsequent endoscopy showed esophageal rupture with protruding cervical fusion metal. Due to operative risks, a percutaneous endoscopic gastrostomy was performed without further infection recurrence...
February 11, 2024: Diagnostics
#25
JOURNAL ARTICLE
Sherri L LaVela, Justina Wu, Andrea L Nevedal, Susan M Frayne, Alex H S Harris, Katherine D Arnow, Kristen Davis, Gary J Farkas, Lorena Reyes, Dan Eisenberg
PURPOSE/OBJECTIVE: Nutrition knowledge, beliefs, and behaviors have important implications for managing and preventing chronic and injury-related secondary conditions in persons with spinal cord injuries and disorders (SCI/D). Yet, the unique dietary and nutritional needs and recommendations specific to individuals with SCI/D and their eating beliefs and behaviors have been understudied. Aim is to describe nutrition and eating beliefs and behaviors from the perspectives of individuals with SCI/D...
February 15, 2024: Rehabilitation Psychology
#26
JOURNAL ARTICLE
Sven Hoekstra, Michelle Trbovich, Wouter Koek, Michael Mader, Marzieh Salehi
STUDY DESIGN: Retrospective longitudinal cohort study of veterans with SCI. OBJECTIVES: Spinal cord injury (SCI) is associated with an increased risk of developing diabetes mellitus (DM), likely due to body composition alterations and autonomic nervous system dysfunction. These factors are more pronounced in persons with tetraplegia (TP) versus paraplegia (PP). However, the effect of level of injury (LOI) on DM incidence is largely unknown. Therefore, the objective is to examine the effect of LOI on DM incidence in persons with SCI...
February 14, 2024: Spinal Cord
#27
Iliass Bourekba, Ismail Halfi, Najwa Ech Cherif Kettani, Meryem Fikri, Mohamed Jidane, Firdaous Touarsa
Heroin-induced leukoencephalopathy (HLE) is a rare toxic encephalopathy associated primarily with heroin inhalation, commonly referred to as "chasing the dragon." This study presents a clinical case of a 27-year-old polydrug user diagnosed with HLE during hospitalization for rapidly progressive flaccid tetraplegia and aphasia. The clinical manifestations encompassed cerebellar and bulbar dysfunction, coupled with motor impairment and altered consciousness. Based on the clinical data and MRI results, HLE was identified as the most likely cause...
January 2024: BJR Case Reports
#28
Moaied Mohamed Ahmed Al Nattah, Simone Tiberti, Leandro Segaletti
In this article, we present a case study involving a patient with spinal cord injury (SCI), resulting in tetraplegia and subsequent loss of upper limb function. The subject of our study was a 23-year-old woman with incomplete tetraplegia stemming from a cervical spinal cord injury. Our primary objective was to enhance hand function and grip strength. Throughout the intervention, we observed substantial enhancements in hand function, range of motion, and muscle power. Notably, the patient exhibited a favorable response to the therapy, demonstrating commendable adherence and active participation...
January 2024: Curēus
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JOURNAL ARTICLE
Inge E Eriks-Hoogland, Michael A Barth, Lorena L Müller, Dominique Braun, Armin Curt, Mohit Arora, James W Middleton, Jürgen Pannek
STUDY DESIGN: Retrospective study OBJECTIVES: To describe the presenting symptoms/signs, clinical course and outcomes in hospitalised people with spinal cord injury (SCI) and symptomatic COVID-19 infections. SETTING: One university hospital and two SCI centres in Switzerland. METHODS: Descriptive analysis of symptoms/signs, clinical course and outcomes of people with SCI with symptomatic COVID-19 infections and need for hospitalisation. RESULTS: Twenty-two people with SCI were included, 15 (68%) were male, median age 64...
February 13, 2024: Spinal Cord Series and Cases
#30
Igor Santos Neto, Tiago Ribeiro, Miguel Guimaraes, Margarida Rodrigues, Fatima Gandarez, Maria Cunha
Spinal cord injury without radiographic abnormality is a condition primarily observed in the pediatric population. However, its occurrence in adults remains underreported. This case report aims to describe a rare instance of adult spinal cord injury without neuroimaging abnormality (SCIWNA) following a road accident in a 52-year-old woman, emphasizing the clinical nuances and management challenges associated with this condition. The patient presented with tetraplegia (American Spinal Injury Association Impairment Scale D) with a neurological injury level at C4, exhibiting subtle improvements during inpatient care...
January 2024: Curēus
#31
JOURNAL ARTICLE
Michelle Trbovich, Yubo Wu, Terry Romo, Wouker Koek, Dean Kellogg
INTRODUCTION: Autonomic dysreflexia (AD) is a potentially life-threatening consequence in high (above T6) spinal cord injury that involves multiple incompletely understood mechanisms. While peripheral arteriolar vasoconstriction, which controls systemic vascular resistance, is documented to be pronounced during AD, the pathophysiological neurovascular junction mechanisms of this vasoconstriction are undefined. One hypothesized mechanism is increased neuronal release of norepinephrine and co-transmitters...
January 27, 2024: Autonomic Neuroscience: Basic & Clinical
#32
JOURNAL ARTICLE
Nathan Dunkelberger, Skye A Carlson, Jeffrey Berning, Eric M Schearer, Marcia K O'Malley
Individuals who have suffered a spinal cord injury often require assistance to complete daily activities, and for individuals with tetraplegia, recovery of upper-limb function is among their top priorities. Hybrid functional electrical stimulation (FES) and exoskeleton systems have emerged as a potential solution to provide upper limb movement assistance. These systems leverage the user's own muscles via FES and provide additional movement support via an assistive exoskeleton. To date, these systems have focused on single joint movements, limiting their utility for the complex movements necessary for independence...
February 8, 2024: IEEE Transactions on Neural Systems and Rehabilitation Engineering
#33
JOURNAL ARTICLE
Farah Naz, Danish Hussain, Hussain Ali, Qasim Raza, Farrukh Siddique
BACKGROUND & OBJECTIVE: Cerebrovascular Accident (CVA) or stroke, Spinal Cord injury can lead to neurological diseases resulting in major loss in motor function causing hemiplegia or tetraplegia. In 2019, according to The Global Burden of Diseases (GBD) CVA/Stroke is the second leading cause of death and the third leading cause of death and disability combined, globally. Its prevalence vary drastically among South Asian countries. The objective of this study was to determine the effectiveness of Functional Electrical Stimulation (FES) machine on neurologically impaired patients at the Physical Therapy department at IHHN, Karachi, Pakistan...
January 2024: Pakistan Journal of Medical Sciences Quarterly
#34
JOURNAL ARTICLE
Ditte Thøgersen, Marie Svensmark Krag, Johanne Staugaard Johansen, Anette Jørgensen
When patients are brought to the emergency room with a traumatic injury to the spinal cord, the road to recovery is long and uncertain. In minutes, their lives have been irreversibly altered. Time will tell if the paralysis to the limbs is permanent or if some degree of mobility or sensation can be reacquired. To many patients, the first weeks feel almost unreal. They find themselves in a state of shock, and feelings of uncertainty and loss of control are dominating. Spinal cord injuries are treated in multiple specialized hospital units...
February 1, 2024: Social Science & Medicine
#35
JOURNAL ARTICLE
Christian Geroin, Martina Petracca, Sonia Di Tella, Enrico Marcuzzo, Roberto Erro, Sofia Cuoco, Roberto Ceravolo, Sonia Mazzucchi, Andrea Pilotto, Alessandro Padovani, Luigi Michele Romito, Roberto Eleopra, Mario Zappia, Alessandra Nicoletti, Carlo Dallocchio, Carla Arbasino, Francesco Bono, Vincenzo Laterza, Benedetta Demartini, Orsola Gambini, Nicola Modugno, Enrica Olivola, Laura Bonanni, Alberto Albanese, Gina Ferrazzano, Alessandro Tessitore, Leonardo Lopiano, Giovanna Calandra-Buonaura, Francesca Morgante, Marcello Esposito, Antonio Pisani, Paolo Manganotti, Lucia Tesolin, Francesco Teatini, Serena Camozzi, Tommaso Ercoli, Fabrizio Stocchi, Mario Coletti Moja, Giovanni Defazio, Michele Tinazzi
BACKGROUND: Functional motor disorders (FMD) are a frequent neurological condition affecting patients with movement disorders. Commonly described in younger adults, their manifestation can be also associated to an elderly onset. OBJECTIVE: To assess the prevalence and describe the clinical manifestations of FMD with elderly and younger onset and their relationship with demographical and clinical variables. METHODS: We recruited patients with a "clinically definite" diagnosis of FMD from the Italian Registry of FMD...
January 2024: Movement Disorders Clinical Practice
#36
JOURNAL ARTICLE
Kelsey Berryman, Marissa Wirth, Charles H Bombardier, Robert W Motl, Brian Bartle, R Lorie Jacob, Keith Aguina, Sherri L LaVela
OBJECTIVE: To identify variables independently associated with moderate to high loneliness in individuals living with Spinal Cord Injuries or Disorders (SCI/D). DESIGN: A cross-sectional, national survey of a random sample of community-dwelling Veterans with SCI/D in the United States. Survey methodology was used to collect data on demographic and injury characteristics, general health, chronic and SCI-secondary conditions, and loneliness. SETTING: The VHA SCI/D System of Care including 25 regional SCI/D Centers (or Hubs)...
January 26, 2024: Archives of Physical Medicine and Rehabilitation
#37
JOURNAL ARTICLE
Luigi Grisoni, Giulio Piperno, Quentin Moreau, Marco Molinari, Giorgio Scivoletto, Salvatore Maria Aglioti
Motor activation in response to perception of action-related stimuli may depend on a resonance mechanism subserving action understanding. The extent to which this mechanism is innate or learned from sensorimotor experience is still unclear. Here, we recorded EEG while people with paraplegia or tetraplegia consequent to spinal cord injury (SCI) and healthy control participants were presented with action sounds produced by body parts (mouth, hands or feet) that were or were not affected by SCI. Non-action sounds were used as further control...
January 26, 2024: European Journal of Neuroscience
#38
JOURNAL ARTICLE
Terese Wilhelmsen, Anne Marie Lannem, Marit Sørensen, Marika Augutis, Henrik Gustafsson
This study explored the physical, social, and psychological benefits of an active rehabilitation (AR) camp as experienced by participants with spinal cord injury (SCI), and perceived fitness and mastery of being physically active six months after the camp. The study used a mixed-method design with pre- ( n = 23), post- ( n = 23), and follow-up questionnaires ( n = 18) and individual interviews ( n = 8). Fuzzy qualitative comparative analysis (fsQCA) was used to analyze the quantitative data and qualitative content analysis was used to analyze the qualitative data...
December 25, 2023: Journal of Functional Morphology and Kinesiology
#39
REVIEW
Kaitlyn Voity, Tara Lopez, Jessie P Chan, Brian D Greenwald
Locked-in syndrome (LIS) is a rare and challenging condition that results in tetraplegia and cranial nerve paralysis while maintaining consciousness and variable cognitive function. Once acute management is completed, it is important to work with the patient on developing a plan to maintain and improve their quality of life (QOL). A key component towards increasing or maintaining QOL within this population involves the establishment of a functional communication system. Evaluating cognition in patients with LIS is vital for evaluating patients' communication needs along with physical rehabilitation to maximize their QOL...
January 17, 2024: Brain Sciences
#40
JOURNAL ARTICLE
Krzysztof Wasiak, Justyna Frasuńska, Beata Tarnacka
Regaining greater independence in performing daily activities constitutes a priority for people with tetraplegia following spinal cord injury (SCI). The highest expectations are connected with the improvement of hand function. Therefore, it is so important for the clinician to identify reliable and commonly applicable prognostic factors for functional improvement. The aim of this study was to conduct an analysis to assess the impact of initial functional factors on the clinical improvement in patients during early neurological rehabilitation (ENR)...
January 6, 2024: Diagnostics
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