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https://www.readbyqxmd.com/read/28222564/neurological-and-functional-recovery-in%C3%A2-tuberculosis-patients-with-spinal-cord%C3%A2-injury-in-the-netherlands
#1
Eva M N Wouda, Ymkje Stienstra, Tjip S van der Werf, Huib Kerstjens, Wiel C M de Lange, Maarten Coppes, Jos Kuijlen, Marga Tepper, Onno W Akkerman
BACKGROUND: Spinal tuberculosis (TB) accounts for approximately 1% to 3% of all TB cases and it can cause a wide range of neurological symptoms, from none to a complete spinal cord injury (SCI), resulting in complete paraplegia or tetraplegia. OBJECTIVES: To describe the functional and neurological outcome of SCI caused by TB. METHODS: Retrospective data on the admission period was combined with prospectively collected data on long-term follow-up...
February 10, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28216346/evaluation-of-visible-spinal-arteries-on-computed-tomography-angiography-before-and-after-branched-stent%C3%A2-graft-repair-for-thoracoabdominal-aortic-aneurysm
#2
Konstantinos Gallis, Piotr M Kasprzak, Beatrix Cucuruz, Reinhard Kopp
OBJECTIVE: The aim of this study was to evaluate the impact of intercostal and lumbar segmental arteries (SAs) detectable on computed tomography angiography (CTA) on the risk of spinal cord ischemia (SCI) in patients undergoing single-step or two-staged branched endovascular aneurysm repair (BEVAR). METHODS: A retrospective analysis of patients treated with branched stent grafts for thoracoabdominal aortic aneurysm at a single institution from January 2009 to June 2015 was performed...
February 16, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28210528/atraumatic-spinal-cord-injury-in-the-novice-surfer-a-comprehensive-review-and-update
#3
Christian Swinney, David Flick, Moses Cheng
Novice surfers are at risk for a rare but potentially devastating form of atraumatic myelopathy. There are 16 published studies on this condition, including 66 cases. The most common suggested mechanism of injury is static hyperextension. However, active mechanisms, in contrast to static, have also been proposed and may be contributory. First time surfers, defined as those who have never been on a surfboard prior to the day of injury, are at particular risk. These individuals make up 89.5%-100% of the reported novice surfers found in the various reports...
February 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28206686/nte-pnpla6-is-expressed-in-mature-schwann-cells-and-is-required-for-glial-ensheathment-of-remak-fibers
#4
Janis McFerrin, Bruce L Patton, Elizabeth R Sunderhaus, Doris Kretzschmar
Neuropathy target esterase (NTE) or patatin-like phospholipase domain containing 6 (PNPLA6) was first linked with a neuropathy occurring after organophosphate poisoning and was later also found to cause complex syndromes when mutated, which can include mental retardation, spastic paraplegia, ataxia, and blindness. NTE/PNPLA6 is widely expressed in neurons but experiments with its Drosophila orthologue Swiss-cheese (SWS) suggested that it may also have glial functions. Investigating whether NTE/PNPLA6 is expressed in glia, we found that NTE/PNPLA6 is expressed by Schwann cells in the sciatic nerve of adult mice with the most prominent expression in nonmyelinating Schwann cells...
February 16, 2017: Glia
https://www.readbyqxmd.com/read/28203407/thoracoabdominal-aortic-replacement-for-crawford-extent-ii-aneurysm-after-thoracic-endovascular-aortic-repair
#5
Haiou Hu, Tie Zheng, Junming Zhu, Yongmin Liu, Ruidong Qi, Lizhong Sun
BACKGROUND: The surgical treatment of Crawford extent II aneurysms after thoracic endovascular aortic repair (TEVAR) remains challenging, because of the need to remove the failed endograft and the complexity of the aortic reconstruction. We retrospectively reviewed our experience with surgical management of Crawford extent II aneurysms after TEVAR using thoracoabdominal aortic replacement (TAAR). METHODS: Eleven patients (10 males, 1 female) with Crawford extent II aneurysm after TEVAR were treated with TAAR between August 2012 and May 2015...
January 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28203369/is-endovascular-treatment-with-multilayer-flow-modulator-stent-insertion-a-safe-alternative-to-open-surgery-for-high-risk-patients-with-thoracoabdominal-aortic-aneurysm
#6
Carolline Pinto, George Garas, Leanne Harling, Ara Darzi, Roberto Casula, Thanos Athanasiou
A best evidence topic in cardiothoracic and vascular surgery was written according to a structured protocol. The question addressed was whether endovascular treatment with multilayer flow modulator stents (MFMS) can be considered a safe alternative to open surgery for high-risk patients with thoracoabdominal aortic aneurysm (TAAA). Altogether 27 papers were identified using the reported search, of which 11 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes, results, and study limitations are tabulated...
March 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28198660/prediction-of-functional-recovery-six-months-following-traumatic-spinal-cord-injury-during-acute-care-hospitalization
#7
Andréane Richard-Denis, Debbie Feldman, Cynthia Thompson, Jean-Marc Mac-Thiong
OBJECTIVES: To determine factors associated with functional status six months following a traumatic cervical and thoracic spinal cord injury (SCI), with a particular interest in factors related to the acute care hospitalization stay. DESIGN: This is a prospective cohort study. Sixteen potential predictive variables were studied. Univariate regression analyses were first performed to determine the strength of association of each variable independently with the total Spinal Cord Independence Measure (SCIM) score...
February 15, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28195350/overcoming-the-divide-between-ataxias-and-spastic-paraplegias-shared-phenotypes-genes-and-pathways
#8
REVIEW
Matthis Synofzik, Rebecca Schüle
Autosomal-dominant spinocerebellar ataxias, autosomal-recessive spinocerebellar ataxias, and hereditary spastic paraplegias have traditionally been designated in separate clinicogenetic disease classifications. This classification system still largely frames clinical thinking and genetic workup in clinical practice. Yet, with the advent of next-generation sequencing, phenotypically unbiased studies have revealed the limitations of this classification system. Various genes (eg, SPG7, SYNE1, PNPLA6) traditionally rooted in either the ataxia or hereditary spastic paraplegia classification system have now been shown to cause ataxia on the one end of the disease continuum and hereditary spastic paraplegia on the other...
February 14, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28190545/prevalence-of-depressive-disorder-in-persons-with-type-2-diabetes-a-national-population-based-cohort-study-2000-2010
#9
Hung-Pin Tu, Hui-Min Hsieh, Tai-Ling Liu, He-Jiun Jiang, Peng-Wei Wang, Chun-Jen Huang
BACKGROUND: Diabetes mellitus, a chronic and disabling disease, is epidemic worldwide. Depressive disorder affects the productivity of workers and leads to disability. OBJECTIVE: This study investigated the prevalence of depressive disorder among persons with type 2 diabetes in Taiwan. METHODS: We extracted service claims data for subjects who had at least 2 ambulatory care service claims or 1 inpatient service claim with a principal diagnosis of type 2 diabetes and at least 1 ambulatory or inpatient service claim with a principal diagnosis of depressive disorder from Taiwan's National Health Insurance Database...
November 17, 2016: Psychosomatics
https://www.readbyqxmd.com/read/28185795/paraplegia-after-accidental-continuous-subdural-analgesia
#10
Jie Chen, Yafang Hu, Liang Lv
Almost all reported cases of unintentional subdural block have described a reversible disorder. We report a patient who developed an incomplete mixed sensory and motor neurological deficit after accidental continuous subdural infusion of 0.1% levobupivacaine given to provide postoperative analgesia after cesarean section. Our report shows that accidental continuous subdural injection can cause permanent neurological sequelae. In the event of suspected compressive neural damage, subdural fluid accumulation, although very rare, should be considered...
December 22, 2016: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/28179632/clinical-exome-sequencing-for-cerebellar-ataxia-and-spastic-paraplegia-uncovers-novel-gene-disease-associations-and-unanticipated-rare-disorders
#11
Bart P van de Warrenburg, Meyke I Schouten, Susanne T de Bot, Sascha Vermeer, Rowdy Meijer, Maartje Pennings, Christian Gilissen, Michèl Aap Willemsen, Hans Scheffer, Erik-Jan Kamsteeg
No abstract text is available yet for this article.
February 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28176970/percutaneous-vertebroplasty-and-interventional-tumor-removal-for-malignant-vertebral-compression-fractures-and-or-spinal-metastatic-tumor-with-epidural-involvement-a-prospective-pilot-study
#12
Yi-Feng Gu, Qing-Hua Tian, Yong-Dong Li, Chun-Gen Wu, Yan Su, Hong-Mei Song, Cheng-Jian He, Dong Chen
OBJECTIVE: The aim of this study was to compare the efficacy of percutaneous vertebroplasty (PVP) and interventional tumor removal (ITR), with PVP alone for malignant vertebral compression fractures and/or spinal metastatic tumor with epidural involvement. PATIENTS AND METHODS: A total of 124 patients were selected for PVP and ITR (n = 71, group A) and PVP alone (n = 53, group B). A 14 G needle and guide wire were inserted into the vertebral body, followed by sequential dilatation of the tract until the last cannula reached the anterior portion of the pedicle...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28169294/factors-predictive-of-survival-and-estimated-years-of-life-lost-in-the-decade-following-nontraumatic-and-traumatic-spinal-cord-injury
#13
B B Hatch, C M Wood-Wentz, T M Therneau, M G Walker, J M Payne, R K Reeves
STUDY DESIGN: Retrospective chart review. OBJECTIVES: To identify factors predictive of survival after spinal cord injury (SCI). SETTING: Tertiary care institution. METHODS: Multiple-variable Cox proportional hazards regression analysis for 759 patients with SCI (535 nontraumatic and 221 traumatic) included age, sex, completeness of injury, level of injury, functional independence measure (FIM) scores, rehabilitation length of stay and SCI cause...
February 7, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28169292/risk-factors-for-community-associated-multidrug-resistant-pseudomonas-aeruginosa-in-veterans-with-spinal-cord-injury-and-disorder-a-retrospective-cohort-study
#14
I O Kale, M A Fitzpatrick, K J Suda, S P Burns, L Poggensee, S Ramanathan, R Sabzwari, C T Evans
STUDY DESIGN: Retrospective cohort studyObjectives:To identify independent risk factors associated with community-associated multidrug-resistant Psedomonas aeruginosa (MDRPA) in a population of veterans with spinal cord injury and disorders (SCI/D). SETTING: A total of 127 Veterans Affairs healthcare facilities. METHODS: Laboratory results from 1 January 2012 to 31 December 2013 were collected, and MDRPA cultures were compared with non-MDRPA cultures...
February 7, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28168342/spinal-rosai-dorfman-disease-case-report-and-literature-review
#15
Haocheng Xu, Fan Zhang, Feizhou Lu, Jianyuan Jiang
OBJECTIVE: Sinus histiocytosis with massive lymphadenopathy or Rosai-Dorfman disease (RDD) is a rare benign disease of dubious etiology that arises predominantly in lymph nodes with generalized fever and malaise. Isolated intraspinal involvement has its unique characteristics. The purpose of this study is to present the largest series of cases in the spinal Rosai-Dorfman disease literature to increase familiarity with its clinicopathologic features, diagnosis, and treatment of RDD from spine...
February 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28165436/management-of-acute-spontaneous-thoracic-spinal-epidural-hematoma-causing-paraplegia
#16
Fahrudin Alić, Hakija Bečulić, Aldin Jusić, Rasim Skomorac, Mirza Moranjkić, Lejla Hrvat, Lejla Tandir
Aim To emphasize the importance of early recognition, diagnostic processing and emergent surgical treatment of spontaneous spinal epidural hematoma (SSEH). Methods A 39-year-old female presented with sudden onset of severe pain between the shoulder blades followed by paraparesis and alerted sensibility in the lower extremities. An hour later she developed paraplegia with sensory deficits below ThIV level, absence of patellar reflex, ankle jerk reflex and sphincter dysfunction. Results Magnetic resonance imaging (MRI) demonstrated acute extensive epidural mass of thoracic spinal segments (ThI-ThIII)...
February 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28160308/invasive-histiocytic-sarcoma-of-the-lumbar-spine-in-a-ferret-mustela-putorius-furo
#17
M Warschau, M Hoffmann, P Dziallas, F Hansmann, W Baumgärtner, R Mischke, S Cichowski, M Fehr
This report describes the history, clinical examination and histopathology of a histiocytic sarcoma in a domestic ferret. Clinical signs were acute paraplegia and dysuria. Physical examination revealed a firm, smooth, touch-sensitive mass in and around the lumbar vertebral column. Neurologic examination was consistent with a lesion between spinal cord segments T3 and L3. Magnetic resonance images revealed bone lesions of L2 and L3 combined with compression of the spinal cord due to a homogenous, isointense mass that was diagnosed as a malignant round cell tumour and the ferret was euthanased...
February 2017: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/28158749/atpase-deficient-mitochondrial-inner-membrane-protein-atad3a-disturbs-mitochondrial-dynamics-in-dominant-hereditary-spastic-paraplegia
#18
Helen M Cooper, Yang Yang, Emil Ylikallio, Rafil Khairullin, Rosa Woldegebriel, Kai-Lan Lin, Liliya Euro, Eino Palin, Alexander Wolf, Ras Trokovic, Pirjo Isohanni, Seppo Kaakkola, Mari Auranen, Tuula Lönnqvist, Sjoerd Wanrooij, Henna Tyynismaa
No abstract text is available yet for this article.
January 31, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28150050/sudden-paraplegia-after-lumbar-puncture-as-a-clue-in-the-diagnosis-of-a-patient-with-spinal-dural-arteriovenous-fistula
#19
Carmen García-Cabo, Germán Morís
PURPOSE: Spinal dural arteriovenous fistula (SDAVF) is manifested as congestive myelopathy with progressive motor, sensory and urinary symptoms. Sometimes, clinical picture and magnetic resonance imaging of the spinal cord are not specific and the diagnosis becomes troublesome. METHODS: We present a 68-year-old male with a progressive paraparesis of unknown etiology over the course of 12 months. Immediately after LP, the patient remarked a sudden worsening in muscular balance of his inferior limbs and a worsening of urinary retention...
February 1, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28149080/urodynamic-profile-in-acute-transverse-myelitis-patients-its-correlation-with-neurological-outcome
#20
Anupam Gupta, Sushruth Nagesh Kumar, Arun B Taly
OBJECTIVE: The objective of this study was to observe urodynamic profile of acute transverse myelitis (ATM) patients and its correlation with neurological outcome. PATIENTS AND METHODS: This prospective study was conducted in the neurorehabilitation unit of a tertiary university research hospital from July 2012 to June 2014. Forty-three patients (19 men) with ATM with bladder dysfunction, admitted in the rehabilitation unit, were included in this study. Urodynamic study (UDS) was performed in all the patients...
January 2017: Journal of Neurosciences in Rural Practice
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