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https://www.readbyqxmd.com/read/28820707/prevalence-of-strongyloides-stercoralis-and-other-intestinal-parasite-infections-in-school-children-in-a-rural-area-of-angola-a-cross-sectional-study
#1
María Luisa Ruíz de Alegría Aznar, Karen Colmenares, Mateu Espasa, Arancha Amor, Isabel Lopez, Arlette Ninda, Joaquina Kanjala, Domingas Guilherme, Elena Sulleiro, Begoña Barriga, Eva Gil, Fernando Salvador, Cristina Bocanegra, Teresa López, Milagros Moreno, Israel Molina
Strongyloides stercoralis is widely distributed in the tropics and subtropics. The aim of this study was to determine the prevalence of S. stercoralis and other intestinal parasites and identify the risk factors for infection with S. stercoralis in a rural area of Angola. A cross-sectional study was conducted in school-age children (SAC) in Cubal, Angola. A questionnaire collecting clinical and epidemiological variables was used, and two stool samples were collected. A concentration technique (Ritchie) and a technique for detection of larvae migration (Baermann) were performed...
July 31, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28815724/secreted-products-of-fasciola-hepatica-inhibit-the-induction-of-t-cell-responses-that-mediate-allergy
#2
Conor M Finlay, Anna M Stefanska, Michelle M Coleman, Hanne Jahns, Joseph P Cassidy, Rachel M McLoughlin, Kingston H G Mills
There is evidence from epidemiology studies of a negative association between infection with helminth parasites and the development of allergy and asthma. Here we demonstrate that the excretory/secretory products of the helminth Fasciola hepatica (FHES) protected mice against ovalbumin (OVA)-induced allergic asthma when administered at time of allergen sensitisation. FHES reduced the accumulation of mucus, eosinophils and lymphocytes into the airways of allergen-challenged mice. Furthermore, FHES treatment suppressed Th2 responses in the airways...
August 16, 2017: Parasite Immunology
https://www.readbyqxmd.com/read/28807278/helminth-infections-on-organic-dairy-farms-in-spain
#3
I Orjales, M Mezo, M Miranda, M González-Warleta, F Rey-Crespo, M Vaarst, S Thamsborg, F J Diéguez, J A Castro-Hermida, M López-Alonso
The aim of this study was to assess the prevalence of the major helminth infections affecting organic dairy cattle in northern Spain. Milk and faecal samples were obtained from 443 milking cows. Ostertagia ostertargi and Fasciola hepatica exposure was assessed by detection of specific antibodies in milk samples and F. hepatica infection was diagnosed by the detection of coproantigens in faecal samples. Dictyocaulus viviparus and Calicophoron daubneyi infections were diagnosed by conventional coprological techniques...
August 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28805167/the-in-vitro-anthelmintic-activity-of-the-ethanol-leaf-extracts-of-terminalia-catappa-l-on-fasciola-gigantica
#4
Panat Anuracpreeda, Runglawan Chawengkirttikul, Arin Ngamniyom, Busaba Panyarachun, Panupong Puttarak, Preeyaporn Koedrith, Noppadol Intaratat
At present, there are no medicinal plant extracts currently available for treatment and control of fasciolosis. The present work could provide, for the first study, conclusions on the in vitro fasciolicidal properties of the ethanol extract of Terminalia catappa L. (TcCE) leaves against adult Fasciola gigantica after incubation with RPMI-1640 medium containing the TcCE at various concentrations and times when compared with triclabendazole (TCZ). The relative motility and survival index values of the TcCE-treated flukes decreased at a more rapid rate than the TCZ-treated flukes...
August 14, 2017: Parasitology
https://www.readbyqxmd.com/read/28805164/modelling-the-spatial-distribution-of-fasciola-hepatica-in-bovines-using-decision-tree-logistic-regression-and-gis-query-approaches-for-brazil
#5
S C Bennema, M B Molento, R G Scholte, O S Carvalho, I Pritsch
Fascioliasis is a condition caused by the trematode Fasciola hepatica. In this paper, the spatial distribution of F. hepatica in bovines in Brazil was modelled using a decision tree approach and a logistic regression, combined with a geographic information system (GIS) query. In the decision tree and the logistic model, isothermality had the strongest influence on disease prevalence. Also, the 50-year average precipitation in the warmest quarter of the year was included as a risk factor, having a negative influence on the parasite prevalence...
August 14, 2017: Parasitology
https://www.readbyqxmd.com/read/28798750/heme-oxygenase-1-expression-contributes-to-the-immunoregulation-induced-by-fasciola-hepatica-and-promotes-infection
#6
Paula Carasi, Ernesto Rodríguez, Valeria da Costa, Sofía Frigerio, Natalie Brossard, Verónica Noya, Carlos Robello, Ignacio Anegón, Teresa Freire
Fasciola hepatica, also known as the liver fluke, is a trematode that infects livestock and humans causing fasciolosis, a zoonotic disease of increasing importance due to its worldwide distribution and high economic losses. This parasite immunoregulates the host immune system by inducing a strong Th2 and regulatory T immune response by immunomodulating dendritic cell (DC) maturation and alternative activation of macrophages. In this paper, we show that F. hepatica infection in mice induces the upregulation of heme-oxygenase-1 (HO-1), the rate-limiting enzyme in the catabolism of free heme that regulates the host inflammatory response...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28764235/immunodiagnosis-of-human-fascioliasis-an-update-of-concepts-and-performances-of-the-serological-assays
#7
REVIEW
Bahador Sarkari, Samaneh Abdolahi Khabisi
Human Fascioliasis (HF) is a foodborne neglected parasitic disease caused by Fasciola hepatica and Fasciola gigantica. New epidemiological data suggest that the endemic areas of the disease are expanding and HF is being reported from areas where it was previously not observed. Diagnosis of HF is challenging. Performances of parasitological approaches, based on the detection of parasite's egg in the stool, are not satisfactory. Currently serological methods for the diagnosis of HF are mainly based on detection of anti-Fasciola antibodies in serum...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28761485/molecular-determination-of-fasciola-spp-isolates-from-domestic-ruminants-fecal-samples-in-the-northwest-of-iran
#8
Abbas Imani Baran, Habib Cheraghi Saray, Farzad Katiraee
BACKGROUND: Fasciola species are the main causes for fascioliasis with great financial losses and are among the most important food/water-borne parasites worldwide. The basic proceedings such as epidemiology and effective control of fascioliasis rely mainly on precise identification of Fasciola species. The present study was conducted to determine the Fasciola species in ruminant fecal samples from East Azerbaijan Province in Iran. METHODS: Overall, 2012 fecal samples were collected and processed initially for microscopic examination of Fasciola eggs in 2014-15...
April 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28761475/the-helminths-causing-surgical-or-endoscopic-abdominal-intervention-a-review-article
#9
REVIEW
Erdal Uysal, Mehmet Dokur
BACKGROUND: Helminths sometimes require surgical or endoscopic intervention. Helminths may cause acute abdomen, mechanical intestinal obstruction, gastrointestinal hemorrhage, perforation, hepatitis, pancreatitis, and appendicitis. This study aimed to determine the surgical diseases that helminths cause and to gather, analyze the case reports, case series and original articles about this topic in literature. METHODS: This study was designed as a retrospective observational study...
April 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28761457/in-vitro-assay-of-paecilomyces-lilacinus-biocontrol-effects-on-fasciola-hepatica-eggs-illustrated-in-scanning-electron-micrographs
#10
Faezeh Najafi, Sasan Rezaie, Eshrat Beigom Kia, Mahmoud Mahmoudi, Sadegh Khodavaisy, Mehdi Mohebali, Mohammad Javad Gharagozlou, Mohammad Bagher Rokni, Gholamreza Mowlavi
BACKGROUND: Fascioliasis is a zoonotic disease caused by the liver fluke Fasciola hepatica. Drug resistance, high costs of treatment and economic losses in meat production have emerged the need of alternative control measures into consideration. The aim of this study was to evaluate the in vitro ovicidal activity of Paecilomyces lilacinus fungus on F. hepatica eggs. METHODS: P. lilacinus isolated from the soil of natural environment was challenged on F. hepatica eggs to observe the bio control effect of nematophagous fungi on trematode helminth eggs...
January 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28747239/palaeoparasitology-and-palaeogenetics-review-and-perspectives-for-the-study-of-ancient-human-parasites
#11
Nathalie M-L Côté, Matthieu LE Bailly
While some species of parasites can be identified to species level from archaeological remains using microscopy (i.e. Enterobius vermicularis, Clonorchis sinensis), others can only be identified to family or genus level as different species produce eggs with similar morphology (i.e. Tænia sp. and Echinococcus sp.). Molecular and immunological approaches offer the possibility to provide more precise determination at the species level. They can also identify taxa when classic parasite markers such as eggs or cysts have been destroyed over time...
July 27, 2017: Parasitology
https://www.readbyqxmd.com/read/28734749/understanding-the-main-route-of-drug-entry-in-adult-fasciola-hepatica-further-insights-into-closantel-pharmacological-activity
#12
L Ceballos, C Canton, G Cadenazzi, K Larsen, G Virkel, L Moreno, I Fairweather, C Lanusse, L Alvarez
Closantel (CLS) is highly effective against adult liver flukes after its oral or subcutaneous (sc) administration in ruminants. Trans-tegumental diffusion and oral ingestion are the two potential routes available for the entry of drugs into Fasciola hepatica. The work reported here contributes to improve the understanding of CLS pharmacology. The main goals of were: I) to determine the pattern of in vivo CLS accumulation into adult F. hepatica and relevant tissues in CLS-treated sheep; II) to investigate the influence of the physicochemical composition of the incubation medium on the CLS diffusion process into adult F...
July 19, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28725301/review-of-infectious-etiology-of-acute-pancreatitis
#13
REVIEW
Prashanth Rawla, Sathyajit S Bandaru, Anantha R Vellipuram
While gallstones and alcoholism are widely known to be the most common causative agents of acute pancreatitis, about 10% of cases are thought to be caused by infectious microorganisms. These microorganisms include viruses (e.g. mumps, Coxsackie B, and hepatitis), bacteria (e.g. Mycoplasma pneumoniae and leptospirosis), and parasites (e.g. Ascaris lumbricoides, Fasciola hepatica, and hydatid disease). Each organism causes acute pancreatitis through diverse mechanisms. The review is primarily conducted in an attempt to provide a better understanding of the possibility of acute pancreatitis presenting as a complication relating to these organisms, and the aim is to guide future diagnoses, management, and predictions of complications...
June 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28719964/discovery-of-parasite-eggs-in-archeological-residence-during-the-15th-century-in-seoul-korea
#14
Pyo Yeon Cho, Jung-Min Park, Myeong-Ki Hwang, Seo Hye Park, Yun-Kyu Park, Bo-Young Jeon, Tong-Soo Kim, Hyeong-Woo Lee
During civil engineering construction near Sejong-ro, Jongro-ku, Seoul, cultural sites were found that are thought to have been built in the 15th century. This area was home to many different people as well as the leaders of the Yi dynasty. To gain further insight into the life styles of the inhabitants of the old capital, soil samples were collected from various areas such as toilets, water foundations, and drainage ways. Parasite eggs were examined by microscopy after 5 g soil samples were rehydrated in 0...
June 2017: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28716204/a-protocol-to-identify-and-minimise-selection-and-information-bias-in-abattoir-surveys-estimating-prevalence-using-fasciola-hepatica-as-an-example
#15
Rebecca I Carroll, Andrew Forbes, David A Graham, Locksley L McV Messam
Abattoir surveys and findings from post-mortem meat inspection are commonly used to estimate infection or disease prevalence in farm animal populations. However, the function of an abattoir is to slaughter animals for human consumption, and the collection of information on animal health for research purposes is a secondary objective. This can result in methodological shortcomings leading to biased prevalence estimates. Selection bias can occur when the study population as obtained from the abattoir is not an accurate representation of the target population...
September 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28710977/assessing-the-toxicity-and-risk-of-salt-impacted-winter-road-runoff-to-the-early-life-stages-of-freshwater-mussels-in-the-canadian-province-of-ontario
#16
R S Prosser, Q Rochfort, R McInnis, K Exall, P L Gillis
In temperate urbanized areas where road salting is used for winter road maintenance, the level of chloride in surface waters has been increasing. While a number of studies have shown that the early-life stages of freshwater mussels are particularly sensitive to salt; few studies have examined the toxicity of salt-impacted winter road runoff to the early-life stages of freshwater mussels to confirm that chloride is the driver of toxicity in this mixture. This study examines the acute toxicity of field-collected winter road runoff to the glochidia of wavy-rayed lampmussels (Lampsilis fasciola) (48 h exposure) and newly released juvenile fatmucket mussels (Lampsilis siliquoidea) (<1 week old; 96 h exposure) under different water hardness...
July 12, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28710478/recombinant-fasciola-hepatica-fatty-acid-binding-protein-suppresses-toll-like-receptor-stimulation-in-response-to-multiple-bacterial-ligands
#17
Marcos J Ramos-Benítez, Caleb Ruiz-Jiménez, Vasti Aguayo, Ana M Espino
Recently, we reported that a native Fasciola hepatica fatty acid binding protein (FABP) termed Fh12 is a powerful anti-inflammatory protein capable of suppressing the LPS-induced expression of inflammatory markers in vivo and in vitro. Because the purification of a protein in native form is, in many situations not cost-beneficial and unsuitable for industrial grade scale-up, this study accomplished the task of optimizing the expression and purification of a recombinant form of FABP (Fh15). Additionally, we ascertained whether this molecule could exhibit a similar suppressive effect on TLR-stimulation and inflammatory cytokine expression from macrophages than those previously demonstrated for the native molecule...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28701625/first-report-of-fasciola-larva-infection-in-galbatruncatula-m%C3%A3-ller-1774-gastropoda-lymnaeidae-occurring-in-the-natural-environment-in-hokkaido-japan
#18
Yuma Ohari, Kei Hayashi, Uday Kumar Mohanta, Yasuhiro Kuwahara, Tadashi Itagaki
In Hokkaido, Japan, wild sika deer are highly infected with Fasciola flukes, suggesting that the flukes complete their life cycle via intermediate host snails and definitive host animals occurring in the natural environment. However, infected snails have been found only in cattle farms contaminated with fasciolosis. This study reports the first Fasciola larva infection in Galbatruncatula snails occurring in the Shoro and Atsuma rivers in the natural environment. Molecular analysis revealed that the nad1 haplotype of the larvae was consistent with that of Fasciola adults obtained from sika deer in Hokkaido...
July 13, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28697819/functional-characterization-of-single-domain-cystatin-like-cysteine-proteinase-inhibitors-expressed-by-the-trematode-fasciola-hepatica
#19
Martín Cancela, Ileana Corvo, Edileuza DA Silva, Aline Teichmann, Leda Roche, Alvaro Díaz, José Fransisco Tort, Henrique B Ferreira, Arnaldo Zaha
Cystatins are small, phylogenetically conserved proteins that are tight-binding inhibitors of cysteine proteinases. The liver fluke Fasciola hepatica uses a diverse set of cysteine proteinases of the papain superfamily for host invasion, immune evasion and nutrition, but little is known about the regulation of these enzymes. The aim of this work is to characterize the cystatin repertoire of F. hepatica. For this purpose, we first surveyed the available sequence databases, identifying three different F. hepatica single-domain cystatins...
July 12, 2017: Parasitology
https://www.readbyqxmd.com/read/28691652/migration-of-fasciola-hepatica-newly-excysted-juveniles-is-inhibited-by-high-mannose-and-oligomannose-type-n-glycan-binding-lectins
#20
Andres Garcia-Campos, Alan W Baird, Grace Mulcahy
Fasciola hepatica has both zoonotic importance and high economic impact in livestock worldwide. After ingestion by the definitive host, the Newly Excysted Juveniles (NEJ) penetrate the intestine before reaching the peritoneal cavity. The role of some NEJ-derived proteins in invasion has been documented, but the role of NEJ glycans or lectin-binding receptors during initial infection in the gut is still unknown. To address these questions, the migration of NEJ through rat intestine was recorded at 30 min intervals up to 150 min by two ex vivo methods...
July 10, 2017: Parasitology
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