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https://www.readbyqxmd.com/read/28634648/fasciola-hepatica-a-diver-in-the-biliary-tree
#1
Aires Martins, Álvaro Gonçalves, Teresa Almeida, Luís Lopes, Alberto Midões
Fasciola hepatica is an endemic trematode that affects millions of people worldwide. The human being can be an accidental host through consumption of contaminated food or water. The authors present a case of hepatic fascioliasis in a 69-year-old Portuguese woman who recently traveled from Egypt, Brazil, and India.
June 20, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28633332/anti-fas2-igm-antibodies-in-fasciola-hepatica-infected-patients-with-positive-igg-serology
#2
Liliya Kazantseva, María Del Pilar García Lázaro, Patricia Herrera-Velit, Jose R Espinoza
Background: Fascioliasis is an infectious disease caused by parasites Fasciola hepatica and F. gigantica. Humans are infected by the consumption of vegetables and water contaminated with the infective form of the parasite. Materials and Methods: In this study, an IgM-ELISA with the cysteine proteinase Fas2 antigen was evaluated with sera from 76 patients infected with F. hepatica, 24 patients with other parasite infections and 84 healthy volunteers. Results: IgM-ELISA resulted in 43% positives in F...
March 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28627969/identification-of-potential-inhibitors-of-fasciola-gigantica-thioredoxin1-computational-screening-molecular-dynamics-simulation-and-binding-free-energy-studies
#3
Rohit Shukla, Harish Shukla, Parismita Kalita, Amit Sonkar, Tripti Pandey, Dev Bukhsh Singh, Awanish Kumar, Timir Tripathi
Fasciola gigantica is the causative organism of fascioliasis and is responsible for major economic losses in livestock production globally. F. gigantica thioredoxin1 (FgTrx1) is an important redox-active enzyme involved in maintaining the redox homeostasis in the cell. To identify a potential anti-fasciolid compound, we conducted a structure-based virtual screening of natural compounds from the ZINC database (n = 1,67,740) against the FgTrx1 structure. The ligands were docked against FgTrx1 and 309 ligands were found to have better docking score...
June 19, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28615861/in-vitro-ovicidal-activity-of-peganum-harmala-seeds-extract-on-the-eggs-of-fasciola-hepatica
#4
Mohammad Moazeni, Zahra Sadat Saadaty Ardakani, Mohammad Jamal Saharkhiz, Jafar Jalaei, Ali Asghar Khademolhoseini, Shahab Shams Esfand Abad, Amir Mootabi Alavi
Peganum harmala seeds extract has been previously reported to have antimicrobial and other medicinal properties. The aim of this study was to evaluate the ovicidal activity of the methanolic extract of P. harmala seeds against the eggs of F. hepatica. The phenolic compounds of the methanolic extract of P. harmala seeds were identified by HPLC analysis. Catechin, rutin, p-Coumaric acid, chloregenic acid and hesperetin were found to be the major phenolic compounds. F. hepatica eggs were collected from the gall bladder of naturally infected sheep...
June 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28615853/genotoxic-potential-of-fasciolagigantica-infection-in-experimentally-infected-rabbits
#5
M A Hannan Khan, P A A Shareef, Abdur Rehman, Rizwan Ullah, Lubna Rehman, S M A Abidi
A number of parasitic platyhelminthes are known to cause genotoxicity in humans and animals. However no such information is available on tropical liver fluke, Fasciola gigantica, which incurs huge economic losses worldwide. In the present study the genotoxic potential of F. gigantica infection in rabbits, experimentally infected with the metacercarial cysts of this parasite, has been investigated using the standard comet assay and micronucleus (MNi) test on the isolated hepatocytes and the whole blood from the infected rabbits...
June 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28615851/gastrointestinal-helminthosis-prevalence-and-associated-determinants-in-goats-of-jabalpur-india
#6
Alok Kumar Dixit, Giridhari Das, Ramesh Pratap Singh Baghel
A total of 632 faecal samples of goats of Jabalpur district of Madhya Pradesh state were examined during three years of the study period (November 2012-October 2015), out of which 82.75 % samples were positive for helminthic infections. Among various helminths, maximum prevalence was of strongyles (32.59 %) followed by amphistomes (14.40 %), Moniezia spp. (12.50 %), Strongyloides spp. (0.79 %), Trichuris spp. (0.47 %) and Fasciolagigantica (0.32 %). Year wise prevalence revealed a highly significant (p < 0...
June 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28609848/geochemical-landscapes-as-drivers-of-trace-and-toxic-element-profiles-in-wild-red-deer-cervus-elaphus
#7
Andrew S French, David Shaw, Stuart W Gibb, Mark A Taggart
Tissue concentrations of essential trace and toxic elements in red deer (Cervus elaphus) are associated with the plants, soil and water they ingest. As such, variation in tissue concentrations is associated with variation in local geochemistry and bioavailability of elements. Physiological factors such as liver fluke (Fasciola hepatica) infection, breeding status, and in-tissue element interactions may also affect tissue concentrations, though their effects in red deer are not well understood. The primary objective of this study was therefore to survey wild red deer liver element concentrations across a range of geographically distinct populations during the Scottish red deer stalking season; and, in so doing, establishes element reference ranges while also exploring geographic and temporal variation and physiological factors...
June 9, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28606323/coprodiagnosis-of-echinococcus-granulosus-infection-in-dogs-from-ankara-turkey
#8
Hatice Öge, Semih Öge, Bahadır Gönenç, Oğuz Sarımehmetoğlu, Gökben Özbakış
The present study were undertaken to compare two isolation techniques (centrifugal flotation and sedimentation) for recovering taeniid eggs from faecal samples, to identify E. granulosus DNA from taeniid eggs by PCR, and to determine the prevalence of E. granulosus in dogs in villages. Faecal samples were collected from 100 dogs in Ankara province. Taenia spp. eggs were found in 27% of dogs faeces. Echinococcus granulosus-specific PCR was obtained in 14 (51.85%) of the taeniid eggs-positive samples. As well as finding Taenia eggs in dogs' faeces, we also found eggs of some helminthic parasites; such as Dipylidium caninum, Toxocara canis, Toxascaris leonina, Trichuris sp...
August 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28602837/a-review-on-epidemiology-global-prevalence-and-economical-losses-of-fasciolosis-in-ruminants
#9
REVIEW
Khalid Mehmood, Hui Zhang, Ahmad Jawad Sabir, Rao Zahid Abbas, Muhammad Ijaz, Aneela Zameer Durrani, Muhammad Hassan Saleem, Mujeeb Ur Rehman, Muhammad Kashif Iqbal, Yajing Wang, Hafiz Ishfaq Ahmad, Tariq Abbas, Riaz Hussain, Muhammad Taslim Ghori, Sadaqat Ali, Aman Ullah Khan, Jiakui Li
Fasciolosis is an important plant borne trematode zoonosis in ruminants caused by the Fasciola hepatica and Fasciola gigentica, It is classified as a neglected tropical disease and found in more than 50 countries especially where sheep and cattle are reared. Fasciolosis is a serious animal health problems in many rural and urban areas of world, causing significant financial losses due to decrease in production and viscera condemnation in animals. Accurate diagnosis of fasciolosis is always remained a challenging task for the field practitioners...
June 7, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28601017/effect-of-substituted-phenylamine-antioxidants-on-three-life-stages-of-the-freshwater-mussel-lampsilis-siliquoidea
#10
R S Prosser, P L Gillis, E A M Holman, D Schissler, H Ikert, J Toito, E Gilroy, S Campbell, A J Bartlett, D Milani, J L Parrott, V K Balakrishnan
Substituted phenylamines (SPAs) are incorporated into a variety of consumer products (e.g., polymers, lubricants) in order to increase the lifespan of the products by acting as a primary antioxidant. Based on their physicochemical properties, if SPAs were to enter the aquatic environment, they would likely partition into sediment. No studies to date have investigated the effect of sediment-associated SPAs on aquatic organisms. The current study examined the effect of four SPAs (diphenylamine (DPA); N-phenyl-1-napthylamine (PNA); N-(1,3-dimethylbutyl)-N'-phenyl-1,4-phenylenediamine (DPPDA); 4,4'-methylene-bis[N-sec-butylaniline] (MBA)) on three different life stages of the freshwater mussel, Lampsilis siliquoidea...
June 7, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28585078/associations-between-fasciolosis-and-milk-production-and-the-impact-of-anthelmintic-treatment-in-dairy-herds
#11
Kerstin Köstenberger, Alexander Tichy, Karl Bauer, Peter Pless, Thomas Wittek
Liver fluke is a ubiquitous parasite that causes extensive production losses in cattle and is a zoonosis. The aims of this study were to determine the prevalence of fasciolosis in 178 dairy cattle herds in Styria (federal state of Austria) and its influence on production, to detect the risk factors for infection, and to explore effective strategies in management and control. A questionnaire on farm management, prophylaxis, and therapy was developed and applied. Furthermore, production parameters (milk yield, milk protein content, butter fat content, non-return rate 90, calving to conception interval, service period) were recorded for 2014 and 2015, and a commercial ELISA for detection of Fasciola hepatica antibodies was applied in bulk tank milk in March 2014 and March 2015...
July 2017: Parasitology Research
https://www.readbyqxmd.com/read/28584245/immune-signatures-of-pathogenesis-in-the-peritoneal-compartment-during-early-infection-of-sheep-with-fasciola-hepatica
#12
Maria Teresa Ruiz-Campillo, Veronica Molina Hernandez, Alejandro Escamilla, Michael Stevenson, Jose Perez, Alvaro Martinez-Moreno, Sheila Donnelly, John P Dalton, Krystyna Cwiklinski
Immune signatures of sheep acutely-infected with Fasciola hepatica, an important pathogen of livestock and humans were analysed within the peritoneal compartment to investigate early infection. Within the peritoneum, F. hepatica antibodies coincided with an intense innate and adaptive cellular immune response, with infiltrating leukocytes and a marked eosinophilia (49%). However, while cytokine qPCR analysis revealed IL-10, IL-12, IL-13, IL-23 and TGFβ were elevated, these were not statistically different at 18 days post-infection compared to uninfected animals indicating that the immune response is muted and not yet skewed to a Th2 type response that is associated with chronic disease...
June 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28576343/economic-assessment-of-ostertagia-ostertagi-and-fasciola-hepatica-infections-in-dairy-cattle-herds-in-germany-using-paracalc-%C3%A2
#13
Jane Fanke, Johannes Charlier, Torsten Steppin, Georg von Samson-Himmelstjerna, Jozef Vercruysse, Janina Demeler
The aim of the current study was to estimate economic costs of Ostertagia ostertagi and Fasciola hepatica infections in dairy cattle herds in Germany using the online calculation programme Paracalc(®). Following a questionnaire, survey data were available from 464 farms in 14 federal states. On those farms bulk tank milk (BTM) samples and additionally up to six serum samples collected from first season grazing calves were analysed, using a commercially available ELISA (Boehringer Ingelheim SVANOVA Biotech AB, Uppsala, Sweden), an in-house ELISA (F...
June 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28576342/development-of-a-colloidal-gold-immunochromatographic-strip-based-on-hsp70-for-the-rapid-detection-of-echinococcus-granulosus-in-sheep
#14
Xunhui Zhuo, Yingchao Yu, Xueqiu Chen, Zhuangzhi Zhang, Yi Yang, Aifang Du
Echinococcus granulosus is the causative pathogen of cystic echinococcosis, a serious disease endangering human and animal health. In this study, an immunochromatographic strip was developed based on the recombinant protein Heat shock protein 70 (HSP70) for the serological detection of E. granulosus. The protocol completes within 20min requiring no specialized equipment or chemical reagents, while specificity tests confirmed no cross-reactivity with positive serum of Fasciola hepatica, Haemonchus contortus, Peste des petits ruminants virus (PPRV) and Foot-and-mouth disease virus (FMDV)...
June 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28567390/extracellular-vesicle-mediated-communication-in-host-parasite-interactions-insight-from-fasciola-hepatica
#15
EDITORIAL
Eduardo de la Torre-Escudero, Mark W Robinson
No abstract text is available yet for this article.
May 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28528590/a-review-of-bovine-fasciolosis-and-other-trematode-infections-in-nigeria
#16
N Elelu, M C Eisler
Trematode infections cause serious economic losses to livestock worldwide. Global production losses due to fasciolosis alone exceed US$3 billion annually. Many trematode infections are also zoonotic and thus a public health concern. The World Health Organization has estimated that about 56 million people worldwide are infected by at least one zoonotic trematode species, and up to 750 million people are at risk of infection. Fasciolosis caused by the fluke Fasciola gigantica is endemic in Nigeria and is one of the most common causes of liver condemnation in abattoirs...
May 22, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28507414/a-reducing-trend-of-fasciolosis-in-slaughtered-animals-based-on-abattoir-data-in-south-of-iran
#17
Manoochehr Shabani Kordshooli, Kavous Solhjoo, Belal Armand, Hamidreza Dowlatkhah, Masoud Esmi Jahromi
AIM: Fascioliasis is a zoonosis infection caused by the liver trematodes (Fasciola spp.) which have been considered to be an important disease in livestock. After several large outbreaks, fascioliasis remains one of the serious health concerns of Iran. This study was conducted to evaluate the prevalence and possible trends of fascioliasis in slaughtered animals in South of Iran based on abattoir data during a period of 5 years. MATERIALS AND METHODS: The daily records for cattle, sheep, and goats slaughtered in the abattoir were extracted from the archived documents of the recent 5 years (2011-2015) and used as the source of data...
April 2017: Veterinary World
https://www.readbyqxmd.com/read/28505878/suspended-solid-concentration-reduces-feeding-in-freshwater-mussels
#18
Shaylah Tuttle-Raycraft, Todd J Morris, Josef D Ackerman
We examined the effect of TSS concentration on the clearance rates (CR) of newly transformed juvenile and adult Lampsilis fasciola, L. siliquoidea, Ligumia nasuta, and Villosa iris, as increased total suspended solids (TSS) are thought to interfere with feeding processes. Mussel CR were measured in aerated (or swirled for juveniles) chambers at TSS concentrations up to 15mgL(-1) for laboratory-transformed juveniles, and up to 100mgL(-1) for adult mussels. The CR of one-week old animals increased with TSS concentration, likely due to ontological differences in feeding (pedal vs...
November 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28487699/network-analysis-of-the-systemic-response-to-fasciola-hepatica-infection-in-sheep-reveals-changes-in-fibrosis-apoptosis-toll-like-receptors-3-4-and-b-cell-function
#19
Yan Fu, John A Browne, Kate Killick, Grace Mulcahy
The Trematode Fasciola hepatica is an important cause of disease in livestock and in man. Modulation of immunity is a critical strategy used by this parasite to facilitate its long-term survival in the host. Understanding the underlying mechanisms at a system level is important for the development of novel control strategies, such as vaccination, as well as for increasing general understanding of helminth-mediated immunoregulation and its consequences. Our previous RNA sequencing work identified a large number of differentially expressed genes (DEG) from ovine peripheral blood mononuclear cells (PBMCs) at acute and chronic stages of F...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28458272/high-prevalence-of-cattle-fascioliasis-in-coastal-areas-of-thua-thien-hue-province-vietnam
#20
Nga Thi Nguyen, Thinh Cong LE, Minh Duc Co Vo, Hoang Van Cao, Ly Thi Nguyen, Khanh Thi Ho, Quyet Ngoc Nguyen, Vui Quang Tran, Yasunobu Matsumoto
In Vietnam, especially central Vietnam, patients with fascioliasis are increasingly being reported. Since the fascioliasis is zoonotic, survey on the cattle fascioliasis should be informative for the control of human fascioliasis. In this study, the prevalence of cattle fascioliasis as well as the density of the intermediate host snails, Lymnaea swinhoei and L. viridis, were studied in Thua Thien Hue (TTH) province during 2014-2015. A total of 572 cattle feces were examined from 27 communes in 9 districts. Fasciola eggs were detected in cattle from 24 communes with an average prevalence of 23...
May 1, 2017: Journal of Veterinary Medical Science
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