keyword
MENU ▼
Read by QxMD icon Read
search

Screening computational

keyword
https://www.readbyqxmd.com/read/28231522/novel-2-3-disubstituted-quinazoline-4-3h-one-molecules-derived-from-amino-acid-linked-sulphonamide-as-a-potent-malarial-antifolates-for-dhfr-inhibition
#1
Tarosh S Patel, Satish F Vanparia, Urmila H Patel, Ritu B Dixit, Chaitanya J Chudasama, Bhavesh D Patel, Bharat C Dixit
An optimization of a modified Grimmel's method for N-heterocyclization of Leucine linked sulphonamide leading to 2,3-disustituted-4-quinazolin-(3H)-ones was accomplished. Further, nineteen hybrid quinazolinone motifs (5a-5s) were synthesized by N-heterocyclization reaction under microwave irradiation using TEAA (IL) as green solvent as well as catalyst. The in vitro screening of the hybrid entities against the plasmodium species P. falciparum yielded five antimalarial potent molecules 5g, 5l, 5m, 5n &5p owing comparable activity to the reference drugs...
February 13, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28231452/proteome-scale-identification-classification-and-structural-analysis-of-iron-binding-proteins-in-bread-wheat
#2
Shailender Kumar Verma, Ankita Sharma, Padmani Sandhu, Neha Choudhary, Shailaja Sharma, Vishal Acharya, Yusuf Akhter
Bread wheat is one of the major staple foods of worldwide population and iron plays a significant role in growth and development of the plant. In this report, we are presenting the genome wide identification of iron-binding proteins in bread wheat. The wheat genome derived putative proteome was screened for identification of iron-binding sequence motifs. Out of 602 putative iron-binding proteins, 130 were able to produce reliable structural models by homology techniques and further analyzed for the presence of iron-binding structural motifs...
February 14, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28228945/preoperative-screening-of-thromboembolism-using-plasma-d-dimer-test-and-proximal-vein-compression-ultrasonography-in-japanese-gynecologic-patients
#3
Daisuke Shigemi, Tomohiko Matsuhashi, Takashi Yamada, Seiryu Kamoi, Toshiyuki Takeshita
BACKGROUND: Venous thromboembolism (VTE) is a serious complication of surgery, including gynecologic surgery. The plasma D-dimer test and proximal/distal vein compression ultrasonography are frequently used as an easy, preoperative VTE screening method. However, targeted patients for these two examinations have not been established. PATIENTS/METHODS: We retrospectively reviewed 380 gynecologic surgical patients who underwent preoperative VTE screening including the plasma D-dimer test and proximal/distal vein compression ultrasonography from March 2014 to February 2015...
March 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28228152/cardiac-metastasis-from-colon-cancer-effectively-treated-with-5-fluorouracil-leucovorin-and-oxaliplatin-modified-folfox6-plus-panitumumab-a-case-report
#4
Yoshiki Tsujii, Yoshito Hayashi, Akira Maekawa, Tetsuji Fujinaga, Kengo Nagai, Shunsuke Yoshii, Akihiko Sakatani, Satoshi Hiyama, Shinichiro Shinzaki, Hideki Iijima, Tetsuo Takehara
BACKGROUND: Cardiac metastasis from colorectal cancer is rare. There is little evidence supporting the effectiveness of chemotherapy, and standard therapy for metastatic cardiac tumors has not been established. CASE PRESENTATION: A 76-year-old woman presented with a right ventricle tumor that was detected incidentally on screening cardiac ultrasonography. The initial computed tomography (CT) scan showed the cardiac tumor, which was approximately 40 mm in size, and multiple pulmonary nodules...
February 23, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28227705/an-affordable-cuff-less-blood-pressure-estimation-solution
#5
Monika Jain, Niranjan Kumar, Sujay Deb, Monika Jain, Niranjan Kumar, Sujay Deb, Monika Jain, Sujay Deb, Niranjan Kumar
This paper presents a cuff-less hypertension pre-screening device that non-invasively monitors the Blood Pressure (BP) and Heart Rate (HR) continuously. The proposed device simultaneously records two clinically significant and highly correlated biomedical signals, viz., Electrocardiogram (ECG) and Photoplethysmogram (PPG). The device provides a common data acquisition platform that can interface with PC/laptop, Smart phone/tablet and Raspberry-pi etc. The hardware stores and processes the recorded ECG and PPG in order to extract the real-time BP and HR using kernel regression approach...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227680/a-mobile-platform-for-automated-screening-of-asthma-and-chronic-obstructive-pulmonary-disease
#6
Daniel B Chamberlain, Rahul Kodgule, Richard Ribon Fletcher, Daniel B Chamberlain, Rahul Kodgule, Richard Ribon Fletcher, Daniel B Chamberlain, Richard Ribon Fletcher, Rahul Kodgule
Chronic Obstructive Pulmonary Disease (COPD) and asthma each represent a large proportion of the global disease burden; COPD is the third leading cause of death worldwide and asthma is one of the most prevalent chronic diseases, afflicting over 300 million people. Much of this burden is concentrated in the developing world, where patients lack access to physicians trained in the diagnosis of pulmonary disease. As a result, these patients experience high rates of underdiagnosis and misdiagnosis. To address this need, we present a mobile platform capable of screening for Asthma and COPD...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227414/breast-lesion-detection-and-characterization-with-3d-features
#7
Arathi Sreekumari, K S Shriram, Vivek Vaidya, Arathi Sreekumari, K S Shriram, Vivek Vaidya, Vivek Vaidya, K S Shriram, Arathi Sreekumari
Automated Breast Ultrasound (ABUS) is highly effective as breast cancer screening adjunct technology. Automation can greatly enhance the efficiency of the clinician sifting through the quantum of data in ABUS volumes to spot lesions. We have implemented a fully automatic generic algorithm pipeline for detection and characterization of lesions on such 3D volumes. We compare a wide range of features for region description on their effectiveness at the dual goals of lesion detection and characterization. On multiple feature images, we compute region descriptors at lesion candidate locations obviating the need for explicit lesion segmentation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227382/a-new-approach-for-the-detection-of-architectural-distortions-using-textural-analysis-of-surrounding-tissue
#8
Imad Zyout, Roberto Togneri, Imad Zyout, Roberto Togneri, Roberto Togneri, Imad Zyout
Aiming at improving the performance of computer-aided detection of architectural distortion (AD) in mammograms, this paper investigates whether textural patterns of AD surrounding tissue (ST) have the potential to detect AD signatures. More specifically, for characterizing the presence of AD; we investigated the application of textural analysis for discriminating between AD surrounding tissue and normal breast parenchyma. We evaluated the underlying hypothesis using a dataset of 2544 regions of interest (ROI) obtained from the Digital Database for Screening Mammography (DDSM)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227283/a-method-to-detect-tortuosity-of-vessel-using-non-imaging-ultrasound-approach-in-carotid-structure
#9
Ravindra B Patil, P Krishnamoorthy, Ravindra B Patil, P Krishnamoorthy, Ravindra B Patil, P Krishnamoorthy
Stroke is a leading cause of functional impairments. The typical screening mechanism is to measure localized Peak Systolic Velocity (PSV) and diagnose impending risk associated with stoke by characterizing the PSV values. However, an accurate measurement of PSV using Doppler ultrasound is affected due to the tortuous nature of carotid artery in elder population group as the angle at which acoustic beam strikes the vessel is over or under estimated resulting in improper measure the blood flow velocity. Hence, the proposed approach estimates the degree of tortuosity of the carotid vessel and includes this as calibration parameter to compute an accurate PSV...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227212/classification-of-large-scale-fundus-image-data-sets-a-cloud-computing-framework
#10
Sohini Roychowdhury, Sohini Roychowdhury, Sohini Roychowdhury
Large medical image data sets with high dimensionality require substantial amount of computation time for data creation and data processing. This paper presents a novel generalized method that finds optimal image-based feature sets that reduce computational time complexity while maximizing overall classification accuracy for detection of diabetic retinopathy (DR). First, region-based and pixel-based features are extracted from fundus images for classification of DR lesions and vessel-like structures. Next, feature ranking strategies are used to distinguish the optimal classification feature sets...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227057/mobile-interface-for-neuroprosthesis-control-aiming-tetraplegic-users
#11
Renato G Barelli, Plinio T Aquino, Maria Claudia Ferrari de Castro, Renato G Barelli, Plinio T Aquino Junior, Maria Claudia Ferrari de Castro, Plinio T Aquino, Maria Claudia Ferrari de Castro, Renato G Barelli
This article proposes the development of a mobile interface for controlling a Neuroprosthesis, designed to restore grasp patterns, aiming tetraplegics users at C5 and C6 levels. Human Computer Interface paradigms and usability concepts guide its planning and development to garantee the quality of user's interaction with the system and thus, the sucess and controlability of the neuroprostheses. The number of screens and menus were optimized, thus the user may feel the interface as more intuitive, leading to fast learning and increasing the trust on it...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226792/steady-state-visual-evoked-potential-based-brain-computer-interface-for-cognitive-assessment
#12
Nicolai Westergren, Rasmus L Bendtsen, Troels W Kjaer, Carsten E Thomsen, S Puthusserypady, Helge B D Sorensen, Nicolai Westergren, Rasmus L Bendtsen, Troels W Kjaer, Carsten E Thomsen, S Puthusserypady, Helge B D Sorensen, Troels W Kjaer, Nicolai Westergren, Carsten E Thomsen, Helge B D Sorensen, Rasmus L Bendtsen, S Puthusserypady
Cognitive assessment is of growing importance, with the general population getting older and a rapidly growing incidence of dementia, which is a major public health issue. Treatment of dementia must, to be most effective, start early in the disease process. Thus, early detection of cognitive decline is important. Cognitive decline may be detected using fully-automated computerized assessment. Such systems will provide inexpensive and widely available screenings of cognitive ability. The aim of this pilot study is to develop a real time steady state visual evoked potential (SSVEP) based brain-computer interface (BCI) for neurological cognitive assessment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226787/exploring-the-possibilities-and-limitations-of-multitarget-ssvep-based-bci-applications
#13
Felix Gembler, Piotr Stawicki, Ivan Volosyak, Felix Gembler, Piotr Stawicki, Ivan Volosyak, Piotr Stawicki, Ivan Volosyak, Felix Gembler
Steady state visual evoked potentials (SSVEPs) are the brain signals induced by gazing at a constantly flickering target. Frame-based frequency approximation methods can be implemented in order to realize a high number of visual stimuli for SSVEP-based Brain-Computer Interfaces (BCIs) on ordinary computer screens. In this paper, we investigate the possibilities and limitations regarding the number of targets in SSVEP-based BCIs. The BCI-performance of seven healthy subjects was evaluated in an online experiment with six differently sized target matrices...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226760/a-new-approach-of-oral-cancer-detection-using-bilateral-texture-features-in-digital-infrared-thermal-images
#14
M Chakraborty, S Mukhopadhyay, A Dasgupta, S Patsa, N Anjum, J G Ray, M Chakraborty, S Mukhopadhyay, A Dasgupta, S Patsa, N Anjum, J G Ray, S Patsa, A Dasgupta, N Anjum, M Chakraborty, S Mukhopadhyay, J G Ray
Oral cancer is one of the most prevalent form of cancer and its severity is aggrandized specially among the socio-economically backward population in developing countries. A major fraction of patient population is unable to avail diagnosis for oral cancer due to scarcity of state-of-the-art infrastructure and experienced oral and maxillofacial pathologist. Contemporary gold standard of oral cancer confirmation relies on biopsy report. But biopsy is invasive and thus patients are usually reluctant to undergo this test...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226747/automatic-detection-of-neovascularization-on-optic-disk-region-with-feature-extraction-and-support-vector-machine
#15
Shuang Yu, Di Xiao, Yogesan Kanagasingam, Shuang Yu, Di Xiao, Yogesan Kanagasingam, Di Xiao, Yogesan Kanagasingam, Shuang Yu
Neovascularization (NV) is a definitive indicator for the onset of Proliferative Diabetic Retinopathy (PDR). The new vessels are fragile and prone to bleed, leading to high risk of sudden vision loss. Automatic detection of NV is an important task in automatic Diabetic Retinopathy (DR) screening as a consequence of the unmet requirement between the growing number of DR patients and limited number of ophthalmologists. This paper focuses on the computer aided detection of neovascularization in the optic disk region...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226746/artery-vein-classification-of-retinal-blood-vessels-using-feature-selection
#16
Vishal Vijayakumar, Dara D Koozekanani, Robert White, James Kohler, Sohini Roychowdhury, Keshab K Parhi, Vishal Vijayakumar, Dara D Koozekanani, Robert White, James Kohler, Sohini Roychowdhury, Keshab K Parhi, James Kohler, Keshab K Parhi, Vishal Vijayakumar, Sohini Roychowdhury, Robert White, Dara D Koozekanani
Automated classification of retinal vessels in fundus images is the first step towards measurement of retinal characteristics that can be used to screen and diagnose vessel abnormalities for cardiovascular and retinal disorders. This paper presents a novel approach to vessel classification to compute the artery/vein ratio (AVR) for all blood vessel segments in the fundus image. The features extracted are then subjected to a selection procedure using Random Forests (RF) where the features that contribute most to classification accuracy are chosen as input to a polynomial kernel Support Vector Machine (SVM) classifier...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226684/simplified-computer-aided-detection-scheme-of-microcalcification-clusters-in-digital-breast-tomosynthesis-images
#17
Ji-Wook Jeong, Seung-Hoon Chae, Eun Young Chae, Hak Hee Kim, Young Wook Choi, Sooyeul Lee, Ji-Wook Jeong, Seung-Hoon Chae, Eun Young Chae, Hak Hee Kim, Young Wook Choi, Sooyeul Lee, Sooyeul Lee, Ji-Wook Jeong, Hak Hee Kim, Eun Young Chae, Young Wook Choi, Seung-Hoon Chae
A computer-aided detection (CADe) algorithm for clustered microcalcifications (MCs) in reconstructed digital breast tomosynthesis (DBT) images is suggested. The MC-like objects were enhanced by a Hessian-based 3D calcification response function, and a signal-to-noise ratio (SNR) enhanced image was also generated to screen the MC clustering seed objects. A connected component segmentation method was used to detect the cluster seed objects, which were considered as potential clustering centers of MCs. Bounding cubes for the accepted clustering seed candidate were generated and the overlapping cubes were combined and examined...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226646/comparison-of-data-mining-techniques-applied-to-fetal-heart-rate-parameters-for-the-early-identification-of-iugr-fetuses
#18
G Magenes, R Bellazzi, A Malovini, M G Signorini, G Magenes, R Bellazzi, A Malovini, M G Signorini, R Bellazzi, M G Signorini, G Magenes, A Malovini
The onset of fetal pathologies can be screened during pregnancy by means of Fetal Heart Rate (FHR) monitoring and analysis. Noticeable advances in understanding FHR variations were obtained in the last twenty years, thanks to the introduction of quantitative indices extracted from the FHR signal. This study searches for discriminating Normal and Intra Uterine Growth Restricted (IUGR) fetuses by applying data mining techniques to FHR parameters, obtained from recordings in a population of 122 fetuses (61 healthy and 61 IUGRs), through standard CTG non-stress test...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226423/simple-emg-driven-musculoskeletal-model-enables-consistent-control-performance-during-path-tracing-tasks
#19
Dustin Crouch, He Huang, Dustin Crouch, He Huang, Dustin Crouch, He Huang
Consistent, robust performance is critical for the utility and user-acceptance of neurally-controlled powered upper limb prostheses. We preliminarily evaluated the performance consistency of an electromyography (EMG)-driven controller based on a two degree-of-freedom musculoskeletal hand model, whose simplified structure is more practical for real-time prosthesis control than existing, complex models. Parameters of four virtual muscles were computed by numerical optimization from an able-bodied subject's kinematic and EMG data collected during wrist and metacarpophalangeal (MCP) flexion/extension movements...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225197/prediction-on-dielectric-strength-and-boiling-point-of-gaseous-molecules-for-replacement-of-sf6
#20
Xiaojuan Yu, Hua Hou, Baoshan Wang
Developing the environment-friendly insulation gases to replace sulfur hexafluoride (SF6 ) has attracted considerable experimental and theoretical attentions but without success. A computational methodology was presented herein for prediction on dielectric strength and boiling point of arbitrary gaseous molecules in the purpose of molecular design and screening. New structure-activity relationship (SAR) models have been established by combining the density-dependent properties of the electrostatic potential surface, including surface area and the statistical variance of the surface potentials, with the molecular properties including polarizability, electronegativity, and hardness...
April 15, 2017: Journal of Computational Chemistry
keyword
keyword
34910
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"