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https://www.readbyqxmd.com/read/28449381/predicting-solubility-of-sulfur-a-cosmo-rs-based-approach-to-investigate-electrolytes-for-li-s-batteries
#1
Steffen Jeschke, Patrik Johansson
Lithium-sulfur (Li-S) batteries are in theory, from their basic reactions, very promising from a specific energy density point-of-view, but have bad power rate capabilities. The dissolution of sulfur from the C/S cathodes into the electrolyte is a rate determining and crucial step for the functionality. So far, time-consuming experimental methods, such as HPLC/UV, have been used to quantify the corresponding solubilities. Here, we use a computational fluid phase thermodynamics approach, the conductor-like screening model for real solvents (COSMO-RS), to compute the solubility of sulfur in different binary and ternary electrolytes...
April 27, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28448160/validation-of-anam-for-cognitive-screening-in-a-mixed-clinical-sample
#2
Andrea S Vincent, Tresa M Roebuck-Spencer, L Eugenia Cox-Fuenzalida, Cady Block, James G Scott, Robert Kane
The Automated Neuropsychological Assessment Metrics (ANAM) is a library of computer based tests designed to measure cognitive function at a single time-point or longitudinally for detection of cognitive change. This study sought to validate ANAM as a cognitive screening tool for presence of confirmed neuropsychological diagnosis in an outpatient setting. Retrospective data analysis was conducted for 139 patients referred for outpatient neuropsychological assessment. Clinical diagnosis was made independent of ANAM test results and resulted in a diagnostic mix of both neurologic and psychologic etiologies...
April 27, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28448031/transcriptomic-analysis-of-c-elegans-rna-sequencing-data-through-the-tuxedo-suite-on-the-galaxy-project
#3
Francis R G Amrit, Arjumand Ghazi
Next generation sequencing (NGS) technologies have revolutionized the nature of biological investigation. Of these, RNA Sequencing (RNA-Seq) has emerged as a powerful tool for gene-expression analysis and transcriptome mapping. However, handling RNA-Seq datasets requires sophisticated computational expertise and poses inherent challenges for biology researchers. This bottleneck has been mitigated by the open access Galaxy project that allows users without bioinformatics skills to analyze RNA-Seq data, and the Database for Annotation, Visualization, and Integrated Discovery (DAVID), a Gene Ontology (GO) term analysis suite that helps derive biological meaning from large data sets...
April 8, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28447326/ct-colonography-role-in-fobt-based-screening-programs-for-colorectal-cancer
#4
REVIEW
Lapo Sali, Grazia Grazzini, Mario Mascalchi
Computed tomographic colonography (CTC) is a minimally invasive imaging examination for the colon, and is safe, well tolerated and accurate for the detection of colorectal cancer (CRC) and advanced adenoma. While the role of CTC as a primary test for population screening of CRC is under investigation, the fecal occult blood test (FOBT) has been recommended for population screening of CRC in Europe. Subjects with positive FOBT are invited to undergo total colonoscopy, which has some critical issues, such as suboptimal compliance, contraindications and the possibility of an incomplete exploration of the colon...
April 26, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28446971/navigation-bronchoscopy-for-diagnosis-and-small-nodule-location
#5
REVIEW
Juan A Muñoz-Largacha, Virginia R Litle, Hiran C Fernando
Lung cancer continues to be the most common cause of cancer death. Screening programs for high risk patients with the use of low-dose computed tomography (CT) has led to the identification of small lung lesions that were difficult to identify using previous imaging modalities. Electromagnetic navigational bronchoscopy (ENB) is a novel technique that has shown to be of great utility during the evaluation of small, peripheral lesions, that would otherwise be challenging to evaluate with conventional bronchoscopy...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28446578/brain-negativity-as-an-indicator-of-predictive-error-processing-the-contribution-of-visual-action-effect-monitoring
#6
Michael Joch, Mathias Hegele, Heiko Maurer, Hermann Müller, Lisa Katharina Maurer
The error-(related)-negativity (Ne/ERN) is an event-related potential in the electroencephalogram (EEG) correlating with error processing. Its conditions of appearance prior to terminal external error information suggest that the Ne/ERN is indicative of predictive processes in the evaluation of errors. The aim of the present study was to specifically examine the Ne/ERN in a complex motor task and to particularly rule out other explaining sources of the Ne/ERN aside from error prediction processes. To this end, we focused on the dependency of the Ne/ERN on visual monitoring about the action outcome after movement termination but prior to result feedback (action effect monitoring)...
April 26, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28446181/a-neuromuscular-electrical-stimulation-nmes-and-robot-hybrid-system-for-multi-joint-coordinated-upper-limb-rehabilitation-after-stroke
#7
Wei Rong, Waiming Li, Mankit Pang, Junyan Hu, Xijun Wei, Bibo Yang, Honwah Wai, Xiaoxiang Zheng, Xiaoling Hu
BACKGROUND: It is a challenge to reduce the muscular discoordination in the paretic upper limb after stroke in the traditional rehabilitation programs. METHOD: In this study, a neuromuscular electrical stimulation (NMES) and robot hybrid system was developed for multi-joint coordinated upper limb physical training. The system could assist the elbow, wrist and fingers to conduct arm reaching out, hand opening/grasping and arm withdrawing by tracking an indicative moving cursor on the screen of a computer, with the support from the joint motors and electrical stimulations on target muscles, under the voluntary intention control by electromyography (EMG)...
April 26, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28445553/a-novel-rat-head-gaze-determination-system-based-on-optomotor-responses
#8
Mengbo You, Toshiyuki Yamane, Hiroshi Tomita, Eriko Sugano, Takuya Akashi
The optomotor response of animals is commonly used to measure their visual performance, e.g., rats of different genetically altered strains or various drug tests. With the presentation of stimuli using computer screens or projectors, the common idea focuses on measuring the eye movement or head and/or body movement to characterize changes of the head gaze. However, traditional methods rely on either the invasive fixation of animals, or the judgment of a human observer who reports the stimulus-tracking movements...
2017: PloS One
https://www.readbyqxmd.com/read/28445277/cancer-studies-based-on-secondary-data-analysis-of-the-taiwan-s-national-health-insurance-research-database-a-computational-text-analysis-and-visualization-study
#9
Jui-Kun Chiang, Chih-Wen Lin, Chun-Lung Wang, Malcolm Koo, Yee-Hsin Kao
There has been a surge in the academic publication output based on secondary analyses of the data from the Taiwan's National Health Insurance claim records. It has become a challenge to comprehend such a rapid expansion of the literature. Therefore, this study aimed to explore the conceptual content of National Health Insurance Research Database-based cancer research, using the abstract of articles extracted from PubMed between 2002 and 2015. Search terms including "National Health Insurance Research Database (NHIRD) AND Taiwan," "Taiwan AND population-based," and "Taiwan AND nationwide" were used to search in PubMed with the publication date limited to between 1997 and 2015...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445069/targeted-dereplication-of-microbial-natural-products-by-high-resolution-ms-and-predicted-lc-retention-time
#10
Justine Chervin, Marc Stierhof, Ming Him Tong, Doe Peace, Kine Østnes Hansen, Dagmar Solveig Urgast, Jeanette Hammer Andersen, Yi Yu, Rainer Ebel, Kwaku Kyeremeh, Veronica Paget, Gabriela Cimpan, Albert Van Wyk, Hai Deng, Marcel Jaspars, Jioji N Tabudravu
A new strategy for the identification of known compounds in Streptomyces extracts that can be applied in the discovery of natural products is presented. The strategy incorporates screening a database of 5555 natural products including 5098 structures from Streptomyces sp., using a high-throughput LCMS data processing algorithm that utilizes HRMS data and predicted LC retention times (tR) as filters for rapid identification of known compounds in the natural product extract. The database, named StrepDB, contains for each compound the structure, molecular formula, molecular mass, and predicted LC retention time...
April 26, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28444384/e-science-technologies-in-a-workflow-for-personalized-medicine-using-cancer-screening-as-a-case-study
#11
Ola Spjuth, Andreas Karlsson, Mark Clements, Keith Humphreys, Emma Ivansson, Jim Dowling, Martin Eklund, Alexandra Jauhiainen, Kamila Czene, Henrik Grönberg, Pär Sparén, Fredrik Wiklund, Abbas Cheddad, Þorgerður Pálsdóttir, Mattias Rantalainen, Linda Abrahamsson, Erwin Laure, Jan-Eric Litton, Juni Palmgren
Objective: We provide an e-Science perspective on the workflow from risk factor discovery and classification of disease to evaluation of personalized intervention programs. As case studies, we use personalized prostate and breast cancer screenings. Materials and Methods: We describe an e-Science initiative in Sweden, e-Science for Cancer Prevention and Control (eCPC), which supports biomarker discovery and offers decision support for personalized intervention strategies...
April 21, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28443035/next-speakers-plan-their-turn-early-and-speak-after-turn-final-go-signals
#12
Mathias Barthel, Antje S Meyer, Stephen C Levinson
In conversation, turn-taking is usually fluid, with next speakers taking their turn right after the end of the previous turn. Most, but not all, previous studies show that next speakers start to plan their turn early, if possible already during the incoming turn. The present study makes use of the list-completion paradigm (Barthel et al., 2016), analyzing speech onset latencies and eye-movements of participants in a task-oriented dialogue with a confederate. The measures are used to disentangle the contributions to the timing of turn-taking of early planning of content on the one hand and initiation of articulation as a reaction to the upcoming turn-end on the other hand...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28439523/tsallis-entropy-and-sparse-reconstructive-dictionary-learning-for-exudate-detection-in-diabetic-retinopathy
#13
Vineeta Das, Niladri B Puhan
Computer-assisted automated exudate detection is crucial for large-scale screening of diabetic retinopathy (DR). The motivation of this work is robust and accurate detection of low contrast and isolated hard exudates using fundus imaging. Gabor filtering is first performed to enhance exudate visibility followed by Tsallis entropy thresholding. The obtained candidate exudate pixel map is useful for further removal of falsely detected candidates using sparse-based dictionary learning and classification. Two reconstructive dictionaries are learnt using the intensity, gradient, local energy, and transform domain features extracted from exudate and background patches of the training fundus images...
April 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28438288/novel-quantitative-analysis-of-autofluorescence-images-for-oral-cancer-screening
#14
Tze-Ta Huang, Jehn-Shyun Huang, Yen-Yun Wang, Ken-Chung Chen, Tung-Yiu Wong, Yi-Chun Chen, Che-Wei Wu, Leong-Perng Chan, Yi-Chu Lin, Yu-Hsun Kao, Shoko Nioka, Shyng-Shiou F Yuan, Pau-Choo Chung
OBJECTIVES: VELscope® was developed to inspect oral mucosa autofluorescence. However, its accuracy is heavily dependent on the examining physician's experience. This study was aimed toward the development of a novel quantitative analysis of autofluorescence images for oral cancer screening. MATERIALS AND METHODS: Patients with either oral cancer or precancerous lesions and a control group with normal oral mucosa were enrolled in this study. White light images and VELscope® autofluorescence images of the lesions were taken with a digital camera...
May 2017: Oral Oncology
https://www.readbyqxmd.com/read/28438139/digital-cxr-with-computer-aided-diagnosis-versus-symptom-screen-to-define-presumptive-tuberculosis-among-household-contacts-and-impact-on-tuberculosis-diagnosis
#15
Monde Muyoyeta, Nkatya Chanda Kasese, Deborah Milimo, Isaac Mushanga, Mapopa Ndhlovu, Nathan Kapata, Maureen Moyo-Chilufya, Helen Ayles
BACKGROUND: Household (HH) contact tracing is a strategy that targets high risk groups for TB. Symptom based screening is the standard used to identify HH contacts at risk for TB during HH contact tracing for TB. However, this strategy may be limited due to poor performance in predicting TB. The objective of this study was to compare CXR with Computer Aided Diagnosis (CAD) against symptom screen for defining presumptive TB and how TB detection changes with each method. METHODS: Household contacts of consecutive index bacteriologically confirmed TB cases were visited by study teams and given TB/HIV education to raise awareness of the risk of TB following close contact with a TB patient...
April 24, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28437615/experimental-demonstration-of-feature-extraction-and-dimensionality-reduction-using-memristor-networks
#16
Shinhyun Choi, Jong Hoon Shin, Jihang Lee, Patrick Sheridan, Wei D Lu
Memristors have been considered as a leading candidate for a number of critical applications ranging from non-volatile memory to non-Von Neumann computing systems. Feature extraction, which aims to transform input data from a high dimensional space to a space with fewer dimensions, is an important technique widely used in machine learning and pattern recognition applications. Here, we experimentally demonstrate that memristor arrays can be used to perform principal component analysis (PCA), one of the most commonly-used feature extraction techniques, through online, unsupervised learning...
April 24, 2017: Nano Letters
https://www.readbyqxmd.com/read/28437443/relative-predictive-value-of-lung-cancer-screening-ct-versus-myocardial-perfusion-attenuation-correction-ct-in-the-evaluation-of-coronary-calcium
#17
Grant Bailey, Abigail Healy, Bryan D Young, Esseim Sharma, Judith Meadows, Hyung J Chun, Wen-Chih Wu, Gaurav Choudhary, Alan R Morrison
Coronary artery calcium scores (CACS) from lung cancer screening computed tomography (LCSCT) or myocardial perfusion attenuation correction computed tomography (ACCT) are not routinely performed or reported. CACS from LCSCT and ACCT have not been directly compared in the same patient population. We identified 66 patients who underwent both LCSCT (non-gated) and ECG-gated cardiac CT (CCT) within a 2-year span. Of this population, 40 subjects had also undergone ACCT. Using the Agatston method, CACS for 264 individual vessels from the LCSCT population and for 160 vessels from ACCT population were calculated and evaluated for agreement with ECG-gated CCT as the gold standard...
2017: PloS One
https://www.readbyqxmd.com/read/28436869/establishing-keypoint-matches-on-multimodal-images-with-bootstrap-strategy-and-global-information
#18
Yong Li, Hongbin Jin, Jiatao Wu, Jie Liu
This paper proposes an algorithm of building keypoint matches on multimodal images by combining a bootstrap process and global information. The correct ratio of keypoint matches built with descriptors is typically very low on multimodal images of large spectral difference. To identify correct matches, global information is utilized for evaluating keypoint matches and a bootstrap technique is employed to reduce the computational cost. A keypoint match determines a transformation T and a similarity metric between the reference and the transformed test image by T...
April 19, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28435483/cross-sectional-study-of-risky-substance-use-by-injured-emergency-department-patients
#19
Valerie Strezsak, Janette Baird, Christina S Lee, Michael J Mello
INTRODUCTION: Survey data regarding the prevalence of risky substance use in the emergency department (ED) is not consistent. The objective of this study was to identify the prevalence of risky substance use among injured ED patients based on the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST v3.0). A secondary objective was to report on the feasibility of administering the ASSIST to this population, based on the time to conduct screening. METHODS: This cross-sectional study used screening data from a randomized controlled trial...
April 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28434642/-late-life-depression-or-prodromal-alzheimer-s-disease-which-tools-for-the-differential-diagnosis
#20
A-I Gasser, V Salamin, S Zumbach
INTRODUCTION: Depression and Alzheimer's disease are both very frequent in elderly people. Cognitive deficits are the hallmark of Alzheimer's disease, but they are also common in depressed elderly people who often present cognitive deficits such as memory, attention and executive function problems. On the other hand, people with early Alzheimer's disease demonstrate emotional and behavioral disorders generally encountered in depression such as loss of energy, apathy, mood disorder, and irritability...
April 20, 2017: L'Encéphale
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