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Devendra Kumar, Neerja Trivedi, Rakesh K Dixit
AIMS/BACKGROUND: This study was to investigated the synergistic effect of polyherbal formulations (PHF) of Allium sativum L., Eugenia jambolana Lam., Momordica charantia L., Ocimum sanctum Linn., and Psidium guajava L. in the inhibition/induction of hepatic and intestinal cytochrome P450 (CYPs) and Phase-II conjugated drug metabolizing enzymes (DMEs). Consumption of these herbal remedy has been extensively documented for diabetes treatment in Ayurveda. METHODOLOGY: PHF of these five herbs was prepared, and different doses were orally administered to Sprague-Dawley rats of different groups except control group...
September 2016: Journal of Intercultural Ethnopharmacology
Mohammad M Zarshenas, Arman Zargaran, Michael Blaschke
Cardiovascular diseases (CVD) are of major causes of death worldwide. Complementary and alternative medicines (CAM) are considered as new sources to find preventive and treatment approaches with mostly a historical perspective. Chinese medicine (CM), Persian medicine (PM), Ayurveda and homeopathy are as most popular traditional systems of medicine among various CAM methods. In this survey, we aimed to review most relevant and approved treatment by current investigations on these CAM systems in the field of CVD to present best traditional remedies and treatment approaches...
October 10, 2016: Current Pharmaceutical Design
Bahaderjeet Singh, Prince Sharma, Arun Kumar, Pooja Chadha, Ramandeep Kaur, Amarjeet Kaur
ETHNOPHARMACOLOGICAL RELEVANCE: Tinospora cordifolia (Willd. Hook. f. & Thomson; family: Menispermaceae), has a long history of use in various traditional medicinal systems including "Ayurveda". It is reported to possess anticancer, antidiabetic, antimicrobial, antispasmodic, and antiinflammatory activities. T. cordifolia has also been well documented for production of various bioactive metabolites and their antioxidant activity, but the microorganisms associated with it have been least explored for the same properties...
October 6, 2016: Journal of Ethnopharmacology
Dushani L Palliyaguru, Dionysios V Chartoumpekis, Nobunao Wakabayashi, John J Skoko, Yoko Yagishita, Shivendra V Singh, Thomas W Kensler
Small molecules of plant origin offer presumptively safe opportunities to prevent carcinogenesis, mutagenesis and other forms of toxicity in humans. However, the mechanisms of action of such plant-based agents remain largely unknown. In recent years the stress responsive transcription factor Nrf2 has been validated as a target for disease chemoprevention. Withania somnifera (WS) is a herb used in Ayurveda (an ancient form of medicine in South Asia). In the recent past, withanolides isolated from WS, such as Withaferin A (WA) have been demonstrated to be preventive and therapeutic against multiple diseases in experimental models...
October 4, 2016: Free Radical Biology & Medicine
Syal Kumar, Gustav J Dobos, Thomas Rampp
Traditional Indian medicine (ayurveda) is becoming increasingly popular, with many chronic conditions responding to it well. Most patients begin to take conventional medications as soon as their diagnoses are made, so ayurvedic treatments are usually undergone alongside and/or after conventional medical approaches. A detailed knowledge of the action of food, spices, and medicinal plants is needed in order to understand their potential influence fully. While societal use of ayurvedic plants and Indian spices is commonplace, without ill effect, the use of more concentrated products made from single plants, often in the form of teas or tablets, is of more concern...
October 5, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Syal Kumar, Thomas Rampp, Christian Kessler, Michael Jeitler, Gustav J Dobos, Rainer Lüdtke, Larissa Meier, Andreas Michalsen
OBJECTIVES: Ayurveda is one of the oldest comprehensive healthcare systems worldwide. Ayurvedic massage and physical therapy are frequently used to treat patients with chronic pain syndromes and disorders of the musculoskeletal system. This study aimed to evaluate the effectiveness of Ayurvedic massage in nonspecific chronic low back pain by means of a randomized clinical trial. DESIGN: Sixty-four patients (mean age, 54.8 years; 49 women and 15 men) with chronic low back pain who scored >40 mm on a 100-mm visual analogue scale (VAS) were randomly assigned to a 2-week massage group with 6 hours of Ayurvedic massage and external treatment (n = 32) or to a 2-week local thermal therapy group (n = 32)...
October 5, 2016: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
N K Lohiya, K Balasubramanian, A S Ansari
India is a home for a large variety of plants with remarkable medicinal and pharmacological value. Traditional medicine in the form of Ayurveda, Siddha and Unani has used many of these plants since ancient days for treating and curing various ailments of the body. When it comes to issues related to reproductive health, people still hesitate to discuss and/or accept it openly and hence look for alternate and natural remedies. The various tribal populations distributed across different parts of the country still use these plant extracts in various formulations for maintenance of good health...
October 2016: Andrologia
Rinu K Rana, Rakesh K Patel
BACKGROUND: The involvement of debilitating side effects of allopathic antiasthmatic drugs provides a strong impetus for the development of new herbal therapeutics. Myrica nagi Thunb. (Syn. Kaiphal) of Myricaceae family is a known drug of the Ayurveda system used for the treatment of several diseases including asthma. METHODS: The present study deals with the preparation and phytochemical screening of polar, non-polar and methanolic extracts of Myrica nagi bark followed by the evaluation of their antiasthmatic activity using four different animal experimental models: acetylcholine induced bronchospasm in conscious guinea pigs, acetylcholine induced contraction on isolated guinea pig tracheal chain preparation, compound 48/80 induced mast cell degranulation using rat, and trypsin and egg albumin induced bronchospasm in conscious rat...
September 23, 2016: Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry
Kannan Sridharan, Gowri Sivaramakrishnan
Ayurveda is one of the complementary and alternative systems of medicine requiring generation of high quality evidence for rational practice. Evidence can be generated from study designs and the present study is an attempt to critically assess the registered studies in the field of Ayurveda from clinical trial registry of India. We found low number of trials conducted with more focus required on the quality of these studies to contribute to high quality evidence.
July 2016: Journal of Ayurveda and Integrative Medicine
Padmanabhan Mannangatti, Kamalakkannan Narasimha Naidu
Ayurveda, an ancient system of medicine that is indigenous to India, is believed to be the world's oldest comprehensive health-care system and is now one of the most recognized and widely practiced disciplines of alternative medicine in the world. Medicinal herbs have been in use for treating diseases since ancient times in India. Ayurvedic therapies with medicinal herbs and herbomineral products generally provide relief without much adverse effects even after prolonged administration. Neurodegenerative disorders are a major cause of mortality and disability, and increasing life spans represent one of the key challenges of medical research...
2016: Advances in Neurobiology
N Satheeshkumar, R S K Vijayan, A Lingesh, S Santhikumar, Ch Vishnuvardhan
India has traditionally been known to all over the world for spices and medicinal plants. Spices exhibit a wide range of pharmacological activities. In contemporary, Indian spices are used to rustle up delicious delicacies. However, the Indian spices are more than just adjuvant which adds aroma and fragrance to foods. A few spices are very widely used and grown commercially in many countries, contain many important chemical constituents in the form of essential oil, oleoresin, oleogum, and resins, which impart flavor, pungency, and color to the prepared dishes, simultaneously exerts diverse therapeutic benefits...
2016: Advances in Neurobiology
Deepti Singh, Piyush Kumar Tripathi, Kishor Patwardhan
BACKGROUND: The standards of Ayurveda education in India are being questioned in the recent years and many suggestions related to educational reforms are being put forth by educators and health policy experts. However, the Post Graduate Entrance Examinations (PGEEs) that are carried out to select the candidates to pursue postgraduate programs have received little attention in this context. OBJECTIVES: The objective of this study was to classify the Multiple Choice Questions (MCQs) from Ayurveda PGEEs conducted in different universities of India during the five year period (ranging from 2010 to 2014) into six levels of Bloom's Taxonomy in cognitive domain...
July 2016: Journal of Ayurveda and Integrative Medicine
Pulok K Mukherjee, Ranjit K Harwansh, Shiv Bahadur, Subhadip Banerjee, Amit Kar, Joydeb Chanda, Sayan Biswas, Sk Milan Ahmmed, C K Katiyar
ETHNOPHARMACOLOGICAL RELEVANCE: Ayurveda entails a scientific tradition of harmonious living and its origin can be traced from ancient knowledge contained in Rigveda and Atharvaveda. Ayurveda is a traditional healthcare system of Indian medicine since time immortal. Several Ayurvedic medicines have been exploiting for treatment and management of various diseases in human beings. The several drugs have been developed and practiced from Ayurveda since ancient time to modern practice as 'tradition to trend'...
September 12, 2016: Journal of Ethnopharmacology
Amit Nakanekar
No abstract text is available yet for this article.
April 2016: Ancient Science of Life
G Aswathy, Prasanth Dharmarajan, Ananth Ram Sharma, V K Sasikumar, M R Vasudevan Nampoothiri
Cirrhosis is the final stage of most of the chronic liver diseases and is most invariably complicated by portal hypertension resulting in ascites. A case of chronic liver disease with portal hypertension (cryptogenic cirrhosis), managed at Amrita School of Ayurveda is discussed in this paper. The clinical picture was that of an uncomplicated cirrhotic ascites. Snehapāna (therapeutic oral administration of lipids) followed by virecana (purgation) was done after an initial course of nityavirecana (daily purgation)...
April 2016: Ancient Science of Life
Rajkala S Ramteke, Panchakshari D Patil, Anup B Thakar
For emergency conditions, Ayurveda has never been given importance in recent times. However, there are certain emergency conditions where biomedicine has limitations but, Ayurveda can provide solution. Classics have many references regarding management of acute conditions like syncope, coma, episodic conditions of bronchial asthma, epilepsy, etc., In the present study, a 61 year female patient had a two year history of hypertension and was suffering with coma. She was treated with an Ayurvedic treatment modality...
April 2016: Ancient Science of Life
Vijaykumar Nandvadekar, Sandeep V Binorkar
BACKGROUND: Ayurveda has classified humans according to Deha-Mānasa prakṛti. It has given equal emphasis to both physical and psychological status of the individual. Constitution or configuration is an individual's peculiar set up of body and mind. It is also of importance in etiopathogenesis, prognosis and treatment procedures of various ailments. It is said that nature has its relative roles in causing individual and group differences in their respective cognitive abilities. AIM: The present study was designed to validate and assess the Intelligence Quotient of individuals of different Prakṛtis...
April 2016: Ancient Science of Life
Niteen Ramdas Salve, Debendranath Mishra
CONTEXT: Mādhava is regarded as a 7(th) century Indian Physician who composed two treatises (in Sanskrit) on Ayurveda, the Mādhava Nidāna and Mādhava Cikitsā. The former treatise deals with the diagnosis of diseases while the latter with the treatment using medicinal plants and other recipes. In Mādhava Cikitsā, a common Sanskrit name is found to describe two or more totally different botanical plant species (thus leading to ambiguity) and a distinct botanical species is also found to represent two or more Sanskrit names at several instances...
April 2016: Ancient Science of Life
Christine Tara Peterson, Joseph Lucas, Lisa St John-Williams, J Will Thompson, M Arthur Moseley, Sheila Patel, Scott N Peterson, Valencia Porter, Eric E Schadt, Paul J Mills, Rudolph E Tanzi, P Murali Doraiswamy, Deepak Chopra
The effects of integrative medicine practices such as meditation and Ayurveda on human physiology are not fully understood. The aim of this study was to identify altered metabolomic profiles following an Ayurveda-based intervention. In the experimental group, 65 healthy male and female subjects participated in a 6-day Panchakarma-based Ayurvedic intervention which included herbs, vegetarian diet, meditation, yoga, and massage. A set of 12 plasma phosphatidylcholines decreased (adjusted p < 0.01) post-intervention in the experimental (n = 65) compared to control group (n = 54) after Bonferroni correction for multiple testing; within these compounds, the phosphatidylcholine with the greatest decrease in abundance was PC ae C36:4 (delta = -0...
2016: Scientific Reports
Soumyajit Biswas, Rupa Shaw, Sanjay Bala, Asis Mazumdar
ETHNOPHARMACOLOGICAL RELEVANCE: Medicinal Plant resources of forest origin are extensively used in India for various systems of medicine like Ayurveda, Unani, Homeopathy, Allopathy, Siddha and Ethnic etc. The tribal communities around the Kakrajhore forest in West Medinipur district of West Bengal have their own traditional knowledge based system of curing many diseases using the forest based plant resources similar to ayurveda. The forest comprises of one of the unique treasure and rich source of diversified ethno-botanical wealth and therefore extensive studies is required for proper documentation including ethnomedicinal knowledge of local tribes...
August 30, 2016: Journal of Ethnopharmacology
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