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https://www.readbyqxmd.com/read/28411011/managerial-skills-of-new-practitioner-pharmacists-within-community-practice
#1
Cortney M Mospan, Kristin A Casper, Ashley Coleman, Kyle Porter
OBJECTIVES: To identify managerial skills required in community pharmacy practice, explore new practitioners' previous exposure to these skills, and assess new practitioners' perceived preparedness to take on managerial responsibilities. METHODS: A survey was developed with the use of Qualtrics and distributed by state pharmacy associations using a convenience sample of pharmacists from Iowa, Kentucky, Michigan, Ohio, and Pennsylvania. Pharmacists not practicing in a community pharmacy setting at the time of the study were excluded...
April 12, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28410614/factors-associated-with-high-utilization-in-a-safety-net-setting
#2
Julia Bell, Sara Turbow, Maura George, Mohammed K Ali
BACKGROUND: Patients with frequent hospital readmissions, or high-utilizer patients (HUPs), are a major driver of rising healthcare costs in the United States. This group has a significant burden of medical illness, but less is known about whether or how social determinants of health may drive their increased healthcare use and poor health outcomes. Our study aimed to define the population of HUPs at a large, safety-net hospital system, to understand how these patients differ from patients who are not HUPs, and to analyze how their demographic, medical, and social factors contribute to their healthcare use and mortality rates...
April 14, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28400755/comparative-evaluation-of-four-bacteria-specific-primer-pairs-for-16s-rrna-gene-surveys
#3
Sofie Thijs, Michiel Op De Beeck, Bram Beckers, Sascha Truyens, Vincent Stevens, Jonathan D Van Hamme, Nele Weyens, Jaco Vangronsveld
Bacterial taxonomic community analyses using PCR-amplification of the 16S rRNA gene and high-throughput sequencing has become a cornerstone in microbiology research. To reliably detect the members, or operational taxonomic units (OTUs), that make up bacterial communities, taxonomic surveys rely on the use of the most informative PCR primers to amplify the broad range of phylotypes present in up-to-date reference databases. However, primers specific for the domain Bacteria were often developed some time ago against database versions that are now out of date...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28391603/embedded-clinical-decision-support-in-electronic-health-record-decreases-use-of-high-cost-imaging-in-the-emergency-department-embed-study
#4
Kelly Bookman, David West, Adit Ginde, Jennifer Wiler, Robert McIntyre, Andrew Hammes, Nichole Carlson, David Steinbruner, Matthew Solley, Richard Zane
OBJECTIVE: Evaluate the impact of evidence-based clinical decision support tools integrated directly into provider workflow in the electronic health record on utilization of CT brain, c-spine and pulmonary embolism (PE). METHODS: Validated, well accepted scoring tools for head injury, c-spine injury and pulmonary embolism were embedded into the electronic health record in a manner minimally disruptive to provider workflow. This was a longitudinal, before/after study in 5 emergency departments in a healthcare system with a common electronic health record...
April 9, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28391086/adolescent-smoking-experimentation-as-a-predictor-of-daily-cigarette-smoking
#5
James D Sargent, Joy Gabrielli, Alan Budney, Samir Soneji, Thomas A Wills
OBJECTIVE: The utility of studying substance use during early adolescence depends on how well indicies of lower-level experimentation predict the development of substance use problems. We examined associations between experimental cigarette use at T1, recanting of use 8 months later (T2), and daily smoking at 2 years (T4). METHODS: Longitudinal telephone survey of 6522 US youth aged 10-14, examining lifetime cigarette smoking (none, just puffing, 1-19, 20-100, >100) and recanting (i...
March 28, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28389932/monthly-oral-ibandronate-100%C3%A2-mg-is-as-effective-as-monthly-intravenous-ibandronate-1%C3%A2-mg-in-patients-with-various-pathologies-in-the-movest-study
#6
Hiroshi Hagino, Masako Ito, Junko Hashimoto, Masao Yamamoto, Koichi Endo, Kyoko Katsumata, Yoshihiro Asao, Rumiko Matsumoto, Tetsuo Nakano, Hideki Mizunuma, Toshitaka Nakamura
The non-inferiority of oral ibandronate 100 mg to intravenous (i.v.) ibandronate 1 mg in increasing lumbar spine (LS) bone mineral density (BMD) after 12 months of treatment was demonstrated in the randomized, phase III MOVEST study. We conducted subgroup analyses in the per-protocol set of the study (n = 183 oral ibandronate; n = 189 i.v. ibandronate). In patients with LS BMD T score ≥ -3.0 or < -3.0 at screening, LS BMD gains from baseline were 4.42 and 5.79%, respectively, with oral ibandronate, and 4...
April 7, 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/28389096/shotgun-proteomic-analysis-to-study-the-decrease-of-xenograft-tumor-growth-after-rosemary-extract-treatment
#7
Alberto Valdés, Virginia García-Cañas, Almudena Pérez-Sánchez, Enrique Barrajón-Catalán, Verónica Ruiz-Torres, Konstantin A Artemenko, Vicente Micol, Jonas Bergquist, Alejandro Cifuentes
The antiproliferative activity of Rosemary (Rosmarinus officinalis) has been widely studied in different in vitro and in vivo models, which demonstrate that rosemary extracts inhibit the cellular proliferation due to its ability to interact with a wide spectrum of molecular targets. However, a comprehensive proteomics study in vivo has not been carried out yet. In the present work, the effects of rosemary extract on xenograft tumor growth has been studied and, for the first time, a shotgun proteomic analysis based on nano-LC-MS/MS together with stable isotope dimethyl labeling (DML) has been applied to investigate the global protein changes in vivo...
March 27, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28384407/nitrogen-doped-mesoporous-carbons-for-supercapacitor-electrode-with-high-specific-volumetric-capacitance
#8
Xiaoqing Yang, Hong Ma, Guoqing Zhang
For pursuing the miniaturization of supercapacitors in practical use, it is critical to construct an efficient but limited porosity of nanocarbon-based electrode for simultaneously obtaining a high utilization of energy storage places and high coating density. However, current studies dominantly focus on the enhancement of specific mass capacitance (Cm) by increasing the pore volume and surface area, leading to a low coating density and thereby resulting in a low specific volumetric capacitance (CV). We report herein the fabrication of a nitrogen-doped mesoporous carbon (NNCM), whose tunable pore volume coupled with the fixed mesopore size offers us the possibility to control the coating density, thus optimizing the CV and Cm for different application purposes...
April 6, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28382228/a-novel-pm-motor-with-hybrid-pm-excitation-and-asymmetric-rotor-structure-for-high-torque-performance
#9
Gaohong Xu, Guohai Liu, Xinxin Du, Fangfang Bian
This paper proposes a novel permanent magnet (PM) motor for high torque performance, in which hybrid PM material and asymmetric rotor design are applied. The hybrid PM material is adopted to reduce the consumption of rare-earth PM because ferrite PM is assisted to enhance the torque production. Meanwhile, the rotor structure is designed to be asymmetric by shifting the surface-insert PM (SPM), which is used to improve the torque performance, including average torque and torque ripple. Moreover, the reasons for improvement of the torque performance are explained by evaluation and analysis of the performances of the proposed motor...
May 2017: AIP Advances
https://www.readbyqxmd.com/read/28378064/immigrants-utilization-of-specialist-mental-healthcare-according-to-age-country-of-origin-and-migration-history-a-nation-wide-register-study-in-norway
#10
Dawit Shawel Abebe, Lars Lien, Jon Ivar Elstad
PURPOSE: As the immigrant population rises in Norway, it becomes ever more important to consider the responsiveness of health services to the specific needs of these immigrants. It has been questioned whether access to mental healthcare is adequate among all groups of immigrants. This study aims to examine the use of specialist mental healthcare services among ethnic Norwegians and specific immigrants groups. METHODS: Register data were used from the Norwegian Patient Registry and Statistics Norway...
April 4, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28366545/variation-in-neoadjuvant-chemotherapy-utilization-for-epithelial-ovarian-cancer-at-high-volume-hospitals-in-the-united-states-and-associated-survival
#11
Emma L Barber, Stacie B Dusetzina, Karyn B Stitzenberg, Emma C Rossi, Paola A Gehrig, John F Boggess, Joanne M Garrett
OBJECTIVE: To estimate variation in the use of neoadjuvant chemotherapy by high volume hospitals and to determine the association between hospital utilization of neoadjuvant chemotherapy and survival. METHODS: We identified incident cases of stage IIIC or IV epithelial ovarian cancer in the National Cancer Database from 2006 to 2012. Inclusion criteria were treatment at a high volume hospital (>20 cases/year) and treatment with both chemotherapy and surgery. A logistic regression model was used to predict receipt of neoadjuvant chemotherapy based on case-mix predictors (age, comorbidities, stage etc)...
March 30, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28342307/simple-fabrication-of-pineapple-root-like-palladium-gold-catalysts-as-the-high-efficiency-cathode-in-direct-peroxide-peroxide-fuel-cells
#12
Xin Wang, Ke Ye, Ce Sun, Hongyu Zhang, Kai Zhu, Kui Cheng, Guiling Wang, Dianxue Cao
Pd-Au/TiC electrodes with various three-dimensional structures are obtained by the pulsed potential electro-deposition in PdCl2/HAuCl4 electrolytes. The morphologies of Pd-Au/TiC composite catalysts are significantly dependent on the component of deposited solutions. The surface appearance of Pd-Au catalysts changes from rime-shaped structure, to feather-like construction, then to pineapple root-like structure and finally to flower-like configuration with the increase of PdCl2 content in electrolytes. These particular three-dimensional structures may be very suitable for H2O2 electro-reduction, which assures a high utilization of Pd-Au catalysts and provides a large specific surface area...
March 18, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28327082/out-of-hours-care-in-germany-high-utilization-by-adult-patients-with-minor-ailments
#13
R Leutgeb, P Engeser, S Berger, J Szecsenyi, G Laux
BACKGROUND: Family practitioners (FPs) who work in Out-Of-Hours Care (OOHC) - especially in rural areas - complain about high workload related to low urgency and potentially unnecessary patient presentations with minor ailments. The aim of this study was to describe Reasons for Encounter (RFEs) in primary OOHC taken into account the doctor's perspective in the context of high workload without knowing patients' motives for visiting an OOHC-centre. METHODS: Within this descriptive study, OOHC data from 2012 were evaluated from a German statutory health insurance company in the federal state of Baden-Wuerttemberg...
March 21, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28321828/genome-wide-association-analysis-tracks-bacterial-leaf-blight-resistance-loci-in-rice-diverse-germplasm
#14
Christine Jade Dilla-Ermita, Erwin Tandayu, Venice Margarette Juanillas, Jeffrey Detras, Dennis Nicuh Lozada, Maria Stefanie Dwiyanti, Casiana Vera Cruz, Edwige Gaby Nkouaya Mbanjo, Edna Ardales, Maria Genaleen Diaz, Merlyn Mendioro, Michael J Thomson, Tobias Kretzschmar
BACKGROUND: A range of resistance loci against different races of Xanthomonas oryzae pv. oryzae (Xoo), the pathogen causing bacterial blight (BB) disease of rice, have been discovered and characterized. Several have been deployed in modern varieties, however, due to rapid evolution of Xoo, a number have already become ineffective. The continuous "arms race" between Xoo and rice makes it imperative to discover new resistance loci to enable durable deployment of multiple resistance genes in modern breeding lines...
December 2017: Rice
https://www.readbyqxmd.com/read/28306233/coaxial-three-layered-carbon-sulfur-polymer-nanofibers-with-high-sulfur-content-and-high-utilization-for-lithium-sulfur-batteries
#15
Feng He, Jian Ye, Yuliang Cao, Lifen Xiao, Hanxi Yang, Xinping Ai
Great progress has been made on the cyclability and material utilization in recent development of lithium-sulfur (Li-S) batteries; however, most of the sulfur electrodes reported so far have a considerable low loading of sulfur (60%), which causes a substantial decrease in energy density and is therefore difficult for application in batteries. To deal with this issue, we fabricate a novel sulfur composite with a coaxial three-layered structure, in which sulfur is deposited on carbon fibers and coated with poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate) (PEDOT/PSS), thus enabling a high sulfur loading of 70...
March 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28286001/understanding-high-utilization-of-unscheduled-care-in-pregnant-women-of-low-socioeconomic-status
#16
Pooja K Mehta, Tamala Carter, Cjloe Vinoya, Shreya Kangovi, Sindhu K Srinivas
BACKGROUND: Pregnant high utilizers of unscheduled care may be at particular risk for poor perinatal outcomes, but the drivers of this association have not been explored from the patient perspective. PURPOSE: We sought to understand maternal preference for unscheduled hospital-based obstetric care to inform interventions and improve value of publicly funded care during pregnancy. METHODS: We conducted a comparative qualitative analysis of in-depth semistructured interviews...
March 9, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28267033/factors-influencing-utilization-of-hospital-services-by-adult-sickle-cell-disease-patients-a-systematic-review
#17
Irina Benenson, Yuri Jadotte, Mercedes Echevarria
BACKGROUND: Painful vaso-occlusive crisis is a hallmark of sickle cell disease (SCD) that commonly results in utilization of hospital services. Recurrent use of hospital services by SCD patients is associated with high healthcare costs and adverse clinical outcomes. Understanding the factors influencing the pattern of utilization is a first step in improving medical care of this patient population while reducing healthcare expenditures. OBJECTIVES: The primary objective of this systematic review was to determine what modifiable and non-modifiable factors influence utilization of hospital services by adult SCD patients...
March 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28261340/integrative-oncology-physician-consultations-at-a-comprehensive-cancer-center-analysis-of-demographic-clinical-and-patient-reported-outcomes
#18
Gabriel Lopez, Jennifer McQuade, Lorenzo Cohen, Jane T Williams, Amy R Spelman, Bryan Fellman, Yisheng Li, Eduardo Bruera, Richard T Lee
Background: Integrative oncology (IO) is a relatively new field that seeks to bring evidence-based, non-conventional approaches into conventional oncology care in a coordinated and safe manner. Though complementary and alternative medicine (CAM) are highly utilized by cancer patients, little is known about the characteristics of patients seeking IO consultation. Methods: Patients presenting for an outpatient IO consultation completed a CAM use questionnaire, Measure Yourself Concerns and Wellbeing (MYCaW), Edmonton Symptom Assessment Scale (ESAS), Quality of Life Short Form 12 (SF-12), and post-consultation satisfaction item...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28230996/a-facile-n-mercaptoethoxyglycinamide-mega-linker-approach-to-peptide-thioesterification-and-cyclization
#19
Patrick M M Shelton, Caroline E Weller, Champak Chatterjee
The C-terminal electrophilic activation of peptides by α-thioesterification requires strongly acidic conditions or complex chemical manipulations, which ultimately limit functional group compatibility and broad utility. Herein, we report a readily accessible N-mercaptoethoxyglycinamide (MEGA) solid-phase linker for the facile synthesis of latent peptide α-thioesters. Incubating peptide-MEGA sequences with 2-mercaptoethanesulfonic acid at mildly acidic pH yielded α-thioesters that were directly used in NCL without purification...
March 22, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28230341/graphitic-nanocarbon-selenium-cathode-with-favorable-rate-capability-for-li-se-batteries
#20
Shuai-Feng Zhang, Wen-Peng Wang, Sen Xin, Huan Ye, Ya-Xia Yin, Yu-Guo Guo
A well-organized selenium/carbon nanosheets nanocomposite(Se/CNSs) is prepared by confining chain-like Sen molecules in hierarchically micromesoporous carbon nanosheets. A unique two-dimensional morphology and high graphitization degree of carbon nanosheets benefits fast Li(+)/e(-) access to the active Se, which guarantees a high utilization of Se during the(de)lithiation process. Besides, the chain-like Se molecules confined in the carbon matrix could alleviate the shuttle effect of polyselenides and promise a stable electrochemistry...
March 3, 2017: ACS Applied Materials & Interfaces
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