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https://www.readbyqxmd.com/read/29793011/thoracic-endovascular-aortic-repair-tevar-versus-best-medical-treatment-bmt-for-high-risk-type-b-intramural-hematoma-imh-a-systematic-review-of-clinical-studies
#1
REVIEW
Lin Li, Yuanyong Jiao, Junjie Zou, Xiwei Zhang, Hongyu Yang, Hao Ma
BACKGROUND: To date , thoracic endovascular aortic repair (TEVAR) for type B aortic dissection is favorable, but TEVAR for type B IMH remains uncertain. There are numerous clinical (eg, refractory pain) and radiologic (eg, IMH thickness) factors that are reported to be associated with IMH progression, challenging the treatment for high-risk type B IMH with high risk factors in clinical practice. OBJECTIVE: To perform a systematic review of clinical studies to investigate outcomes of TEVAR+BMT and BMT in the treatment of high-risk type B IMH ...
May 21, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29792940/a-randomized-control-trial-to-determine-the-effectiveness-and-physiological-effects-of-spinal-manipulation-and-spinal-mobilization-compared-to-each-other-and-a-sham-condition-in-patients-with-chronic-low-back-pain-study-protocol-for-the-relief-study
#2
Brian C Clark, David W Russ, Masato Nakazawa, Christopher R France, Stevan Walkowski, Timothy D Law, Megan Applegate, Niladri Mahato, Samuel Lietkam, James Odenthal, Daniel Corcos, Simeon Hain, Betty Sindelar, Robert J Ploutz-Snyder, James S Thomas
BACKGROUND: Low back pain (LBP) is one of the most common reasons for seeking medical care. Manipulative therapies are a common treatment for LBP. Few studies have compared the effectiveness of different types of manipulative therapies. Moreover, the physiologic mechanisms underlying these treatments are not fully understood. Herein, we present the study protocol for The Researching the Effectiveness of Lumbar Interventions for Enhancing Function Study (The RELIEF Study). METHODS AND STUDY DESIGN: The RELIEF Study is a Phase II RCT with a nested mechanistic design...
May 21, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29792372/sativex%C3%A2-as-add-on-therapy-vs-further-optimized-first-line-antispastics-savant-in-resistant-multiple-sclerosis-spasticity-a-double-blind-placebo-controlled-randomised-clinical-trial
#3
Jolana Markovà, Ute Essner, Bülent Akmaz, Marcella Marinelli, Christiane Trompke, Arnd Lentschat, Carlos Vila Silván
Purpose/aim: To evaluate the efficacy of tetrahydrocannabinol [THC]:cannabidiol [CBD] oromucosal spray (Sativex®) as add-on therapy to optimized standard antispasticity treatment in patients with moderate to severe multiple sclerosis (MS) spasticity. METHODS: Sativex as Add-on therapy Vs. further optimized first-line ANTispastics (SAVANT) was a two-phase trial. In Phase A, eligible patients received add-on THC:CBD spray for 4 weeks to identify initial responders (≥ 20% improvement from baseline in spasticity 0-10 numerical rating scale [NRS] score)...
May 24, 2018: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29792312/identification-of-patients-with-hemoglobin-ss-s%C3%AE-0-thalassemia-disease-and-pain-crises-within-electronic-health-records
#4
Ashima Singh, Javier Mora, Julie A Panepinto
Electronic health records (EHRs) are a source of big data that provide opportunities for conducting population-based studies and creating learning health systems, especially for rare conditions such as sickle cell disease (SCD). The objective of our study is to validate algorithms for accurate identification of patients with hemoglobin (Hb) SS/Sβ0 thalassemia and acute care encounters for pain among SCD patients within EHR warehouse. We used data for children receiving care at Children's Hospital of Wisconsin from 2013 to 2016 to test the accuracy of the 2 algorithms...
June 12, 2018: Blood Advances
https://www.readbyqxmd.com/read/29792172/oral-health-and-orofacial-pain-in-people-with-dementia-admitted-to-acute-hospital-wards-observational-cohort-study
#5
Liza J M van de Rijt, Roxane A F Weijenberg, Alexandra R Feast, Victoria Vickerstaff, Frank Lobbezoo, Elizabeth L Sampson
BACKGROUND: Orofacial pain in people with dementia is difficult to detect, and often under-treated. Our aim was to investigate the prevalence of orofacial pain in people with dementia in acute hospitals in the UK. Secondary aims were to examine oral health status and explore associations between orofacial pain and oral health factors. METHODS: This cross-sectional observational study was carried out in two UK hospitals. Using the Orofacial Pain Scale in Non-Verbal Individuals (OPS-NVI) to identify orofacial pain, 101 participants with dementia, admitted to acute medical wards, were observed for at least 3 min during rest and chewing...
May 23, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29791302/preferences-of-adults-with-spinal-cord-injury-for-widely-used-health-related-quality-of-life-and-subjective-well-being-measures
#6
Alina Ionela Palimaru, William E Cunningham, Marcus Dillistone, Arturo Vargas-Bustamante, Honghu Liu, Ron D Hays
OBJECTIVE: To describe preferences for survey instruments on health-related quality of life (HRQOL) and subjective well-being (SWB) among adults with spinal cord injury (SCI), and compare perspectives on the instruments between the United States and the United Kingdom. DESIGN: We conducted 20 in-depth interviews. SETTING: Participants were interviewed in their homes, some in person and some via Skype. PARTICIPANTS: A convenience sample of 20 adults with SCI (10 in the US and 10 in the UK) were recruited via print and on-line advertisements...
May 23, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29791238/low-dose-ketamine-infusion-for-adjunct-management-during-vaso-occlusive-episodes-in-adults-with-sickle-cell-disease-a-case-series
#7
Nicole Palm, Catherine Floroff, Tanna B Hassig, Alice Boylan, Julie Kanter
The optimal management of recurrent painful episodes in individuals living with sickle cell disease (SCD) remains unclear. Currently, the primary treatment for these episodes remains supportive, using fluids and intravenous opioid and anti-inflammatory medications. Few reports have described the use of adjunct subanesthetic doses of ketamine to opioids for treatment of refractory pain in SCD. This article reports a retrospective case series of five patients admitted to the intensive care unit (ICU) with prolonged vaso-occlusive episodes (VOEs)...
May 23, 2018: Journal of Pain & Palliative Care Pharmacotherapy
https://www.readbyqxmd.com/read/29791196/determining-success-or-failure-after-foot-and-ankle-surgery-using-patient-acceptable-symptom-state-pass-and-patient-reported-outcome-information-system-promis
#8
Michael R Anderson, Judith F Baumhauer, Benedict F DiGiovanni, Sam Flemister, John P Ketz, Irvin Oh, Jeffrey R Houck
BACKGROUND: As the role of generic patient-reported outcomes (PROs) expands, important questions remain about their interpretation. In particular, how the Patient Reported Outcome Measurement Instrumentation System (PROMIS) t score values correlate with the patients' perception of success or failure (S/F) of their surgery is unknown. The purposes of this study were to characterize the association of PROMIS t scores, the patients' perception of their symptoms (patient acceptable symptom state [PASS]), and determination of S/F after surgery...
May 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29790635/the-effect-of-12-week-garlic-supplementation-on-symptom-relief-in-overweight-or-obese-women-with-knee-osteoarthritis
#9
Ahmad Salimzadeh, Elham Alipoor, Sahar Dehghani, Mehdi Yaseri, Mostafa Hosseini, Christine Feinle-Bisset, Mohammad Javad Hosseinzadeh-Attar
AIMS: Chronic joint pain and stiffness, and functional disability, are the major debilitating features of osteoarthritis (OA). The aim of this study was to assess the effect of 12-week supplementation with a garlic supplement on knee osteoarthritis outcomes in overweight or obese women. METHODS: Seventy-six postmenopausal overweight or obese women (25≤BMI≤40 kg/m2 ) with medically diagnosed knee OA participated in this randomised double-blind, placebo-controlled, parallel-design trial...
May 23, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29790369/an-innovative-perioperative-pain-program-for-chronic-opioid-users-an-academic-medical-center-s-response-to-the-opioid-crisis
#10
Marie N Hanna, Traci J Speed, Ronen Shechter, Michael C Grant, Rosanne Sheinberg, Elizabeth Goldberg, Claudia M Campbell, Nicholas Theodore, Colleen G Koch, Kayode Williams
Increased utilization of prescription opioids for pain management has led to a nationwide public health crisis with alarming rates of addiction and opioid-related deaths. In the surgical setting, opioid prescriptions have been implicated as a contributing factor to the opioid epidemic. The authors developed an innovative model to address aspects of pain management and opioid utilization during preoperative evaluation, acute surgical hospitalization, and postoperative follow-up for chronic opioid users. This program involves multidisciplinary teams that include acute and chronic pain specialists, psychiatrists, integrative medicine specialists, and physical medicine and rehabilitation services...
May 1, 2018: American Journal of Medical Quality: the Official Journal of the American College of Medical Quality
https://www.readbyqxmd.com/read/29790353/-back-pain-treatment
#11
Marek Hakl
Spine pain is one of the most common medical problems. Yearly incidence is reported between 15 and 45 %, lifelong is 60-90 %. Neurological examination, radiology examination, CT or magnetic resonance imaging are the basic diagnostics. Acute back pain is usually treated monotherapeutically, NSAIDs is the base. Chronic back pain treatment is multidisciplinary, it combines pharmacotherapy, physiotherapy, psychotherapy and other methods. In pharmacotherapy we proceed according to the WHO three-step ladder, including strong opioid medication for strong back pain...
2018: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29790293/the-relationship-between-self-reported-restless-sleep-and-objectively-measured-physical-activity-in-adults-with-knee-osteoarthritis
#12
Abigail L Gilbert, Jungwha Lee, Jing Song, Pamela A Semanik, Linda S Ehrlich-Jones, C Kent Kwoh, Dorothy D Dunlop, Rowland W Chang
OBJECTIVE: Despite many health benefits of physical activity, inactivity is endemic among adults with knee osteoarthritis (KOA). Because sleep quality may be a target to improve physical activity behavior, we investigated the cross-sectional relationship between restless sleep and physical activity in participants with or at risk for KOA. METHODS: We analyzed accelerometer-measured physical activity and clinical data from Osteoarthritis Initiative (OAI) participants...
May 22, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29790166/physical-therapy-as-the-first-point-of-care-to-treat-low-back-pain-an-instrumental-variables-approach-to-estimate-impact-on-opioid-prescription-health-care-utilization-and-costs
#13
Bianca K Frogner, Kenneth Harwood, C Holly A Andrilla, Malaika Schwartz, Jesse M Pines
OBJECTIVE: To compare differences in opioid prescription, health care utilization, and costs among patients with low back pain (LBP) who saw a physical therapist (PT) at the first point of care, at any time during the episode or not at all. DATA SOURCES: Commercial health insurance claims data, 2009-2013. STUDY DESIGN: Retrospective analyses using two-stage residual inclusion instrumental variable models to estimate rates for opioid prescriptions, imaging services, emergency department visits, hospitalization, and health care costs...
May 23, 2018: Health Services Research
https://www.readbyqxmd.com/read/29789774/pilot-study-of-dose-response-effects-of-exercise-on-change-in-c-reactive-protein-cortisol-and-health-related-quality-of-life-among-cancer-survivors
#14
Jeanette M Ricci, Victoria Flores, Isabela Kuroyama, Arash Asher, Heather P Tarleton
Fatigue, stress, and depression contribute to poor health-related quality of life (HRQoL) among cancer survivors. This study examined the effects of combined aerobic and resistance training (CART) on HRQoL and biomarkers of stress. Cancer survivors ( n  = 76, 91% female, 39% breast cancer, 32% gynecologic cancer) were enrolled in CART for three 60-min sessions, weekly, for 26 weeks. Participants completed the National Institutes of Health's Patient Reported Outcomes Measurement Information System (NIH PROMIS) fatigue assessment and the SF-36...
2018: BioResearch Open Access
https://www.readbyqxmd.com/read/29789211/distress-thermometer-for-preoperative-screening-of-patients-with-oral-squamous-cell-carcinoma
#15
Juliana-Theresa Schell, Andrea Petermann-Meyer, Anita Kloss-Brandstätter, Alexander K Bartella, Mohammad Kamal, Frank Hölzle, Bernd Lethaus, Jan Teichmann
In this study, we evaluate the association between distress, various demographic and medical variables, and the prevalence of psychosocial distress in preoperative patients with oral squamous cell carcinoma. A total of 100 consecutive patients were recruited into the study and asked to complete the Distress Thermometer (DT) form with the Problem List questionnaire prior to surgical intervention; the average distress score was 5.7 ± 2.7. The distress score was neither correlated with age (r = -0.025; p = 0...
May 9, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29789018/pain-clinic-definitions-in-the-medical-literature-and-u-s-state-laws-an-integrative-systematic-review-and-comparison
#16
REVIEW
Barbara Andraka-Christou, Joshua B Rager, Brittany Brown-Podgorski, Ross D Silverman, Dennis P Watson
BACKGROUND: In response to widespread opioid misuse, ten U.S. states have implemented regulations for facilities that primarily manage and treat chronic pain, called "pain clinics." Whether a clinic falls into a state's pain clinic definition determines the extent to which it is subject to oversight. It is unclear whether state pain clinic definitions model those found in the medical literature, and potential differences lead to discrepancies between scientific and professionally guided advice found in the medical literature and actual pain clinic practice...
May 22, 2018: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/29789000/spontaneous-splenic-rupture-complicating-primary-varicella-zoster-infection-a-case-report
#17
Aarthy Uthayakumar, David Harrington
BACKGROUND: Primary varicella zoster virus (VZV) infection is a common illness, predominantly affecting children. Its course is typically benign, although severe complications have been described. Splenic rupture is an extremely rare and potentially fatal complication of primary VZV infection, with only a handful of cases reported in the literature. CASE PRESENTATION: A 32-year-old Romanian man with no significant past medical history, presented with a 2 day history of sudden onset, worsening generalised abdominal pain and a 1 day history of vomiting...
May 22, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29788831/lumbosacral-transitional-vertebrae-in-cats-and-its-relationship-to-lumbosacral-vertebral-canal-stenosis
#18
Georgina Harris, Jessica Ball, Steven De Decker
Objectives Although a clear relationship has been demonstrated between the presence of lumbosacral transitional vertebrae and the development of lumbosacral stenosis in dogs, this relationship has not been evaluated in cats. The aim of this study was to investigate the relationship between the presence of lumbosacral transitional vertebrae and lumbosacral stenosis in cats. Methods The medical records and diagnostic imaging studies of 13 cats diagnosed with lumbosacral stenosis were retrospectively reviewed for lumbosacral abnormalities and compared with findings of 405 cats that underwent CT for reasons unrelated to spinal disease...
May 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29788453/myofascial-findings-and-psychopathological-factors-in-patients-with-chronic-pelvic-pain-syndrome
#19
Susanne G R Klotz, Gesche Ketels, Bernd Löwe, Christian A Brünahl
Objective: Chronic pelvic pain syndrome (CPPS) is a common pain condition with psychosocial and somatic symptoms. Myofascial findings and psychiatric comorbidities are frequent. Therefore, the aim of the study was to analyze myofascial and psychosocial aspects. Furthermore, the study focuses on correlations between these aspects and gender differences in this topic. Design: Cross-sectional study. Setting: Interdisciplinary outpatient clinic for patients with CPPS at the University Medical Centre Hamburg-Eppendorf, Germany...
May 19, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29788356/return-to-duty-rates-following-minimally-invasive-spine-surgery-performed-on-active-duty-military-patients-in-an-ambulatory-surgery-center
#20
Elder Granger, Stefan Prada, Zoltan Bereczki, Michael Weiss, Chip Wade, Reginald Davis
Background: Low back pain is a primary health care utilization driver in the US population. Health care evaluation visits for low back pain are as common as medical evaluation for the common cold. Low back pain is the most common reason for reductions in activities of daily living and work activity in the general population. Although these statistics are compelling, in the military population, there is arguably a significantly greater economic impact on the military population, as the cost to train, retain, and deploy a service member is a tremendous cost...
May 21, 2018: Military Medicine
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