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https://www.readbyqxmd.com/read/28079771/advanced-research-and-data-methods-in-women-s-health-big-data-analytics-adaptive-studies-and-the-road-ahead
#1
Christian R Macedonia, Clark T Johnson, Indika Rajapakse
Technical advances in science have had broad implications in reproductive and women's health care. Recent innovations in population-level data collection and storage have made available an unprecedented amount of data for analysis while computational technology has evolved to permit processing of data previously thought too dense to study. "Big data" is a term used to describe data that are a combination of dramatically greater volume, complexity, and scale. The number of variables in typical big data research can readily be in the thousands, challenging the limits of traditional research methodologies...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28079770/neurodevelopmental-outcomes-after-assisted-reproductive-technologies
#2
Jacques Balayla, Odile Sheehy, William D Fraser, Jean R Séguin, Jacquetta Trasler, Patricia Monnier, Andrea A MacLeod, Marie-Noëlle Simard, Gina Muckle, Anick Bérard
OBJECTIVE: To compare children's cognitive, motor, and language development at 2 years of age after assisted reproductive technologies (ARTs) relative to natural conception. METHODS: The 3D-Study (2010-2012) is a prospective cohort study, which sought to improve the understanding among perinatal events, obstetric outcomes, and child development. A total of 2,366 pregnant women were recruited, of whom 278 conceived with ART: ovarian stimulation, intrauterine sperm insemination, in vitro fertilization, intracytoplasmic sperm injection, or in vitro maturation...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28077366/effectiveness-of-acupuncture-in-women-with-polycystic-ovarian-syndrome-undergoing-in-vitro-fertilisation-or-intracytoplasmic-sperm-injection-a-systematic-review-and-meta-analysis
#3
Junyoung Jo, Yoon Jae Lee
OBJECTIVES: The aim of this systematic review was to assess the evidence from randomised controlled trials (RCTs) on the efficacy, effectiveness and safety of acupuncture in women with polycystic ovarian syndrome (PCOS) undergoing in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI). METHODS: We searched a total of 15 databases through October 2015. The participants were women with PCOS (diagnosed using the Rotterdam criteria) undergoing IVF or ICSI...
January 11, 2017: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/28073201/azoospermic-patient-s-treatment-an-experience-of-a-pma-hospital-unit-and-role-of-ultrasonography
#4
Paolo Panella, Pietro Pepe, Placido Borzì, Maria Elena Vento, Michele Pennisi, Paolo Scollo
INTRODUCTION: Azoospermia causes about 10% of male infertility and the best therapeutic option is the retrieval of sperm from testis or epididymis. MATERIAL AND METHODS: From Juanary 2008 to June 2016, 92 men (median 36 years; range: 25-54 years) were submitted in 47 cases to TESE (testicular sperm extraction) and in 45 cases to PESA (percutaneous epididymal sperm aspiration) for secretory and obstructive azoospermia, respectively; moreover, all the patients previously underwent color Doppler ultrasound of the testis and transrectal ultrasound of the prostate...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28071857/risk-of-hypertensive-disorders-in-pregnancy-following-assisted-reproductive-technology-overview-and-meta-analysis
#5
Costas Thomopoulos, George Salamalekis, Konstantinos Kintis, Iliana Andrianopoulou, Helena Michalopoulou, George Skalis, Stefanos Archontakis, Ourania Argyri, Costas Tsioufis, Thomas K Makris, Emmanuel Salamalekis
The extent of the increased risk of pregnancy hypertensive disorders following assisted reproductive technology (ART) was investigated. PubMed and the Cochrane Collaboration Library were used as data sources to identify and select longitudinal cohorts comparing pregnancies following ART with spontaneously conceived pregnancies, between 1978 and June 2016. Risk ratios and 95% confidence intervals (CIs) of three outcomes, ie, gestational hypertension (GH), preeclampsia (PE), and their sum (PHD), were calculated...
November 7, 2016: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28069181/recommendations-for-practices-utilizing-gestational-carriers-a-committee-opinion
#6
(no author information available yet)
This document provides the latest recommendations for evaluation of gestational carriers and intended parents. It incorporates recent information from the US Centers for Disease Control and Prevention, the US Food and Drug Administration, and the American Association of Tissue Banks, with which all programs offering gestational carrier services must be thoroughly familiar. This document replaces the previous document of the same name, last published in 2015 (Fertil Steril 2015; 103:e1-8).
January 6, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28069176/revisiting-the-progesterone-to-oocyte-ratio
#7
Micah J Hill, Mae Wu Healy, Kevin S Richter, Eric Widra, Eric D Levens, Alan H DeCherney, George Patounakis, Brian W Whitcomb
OBJECTIVE: To critically evaluate the P to oocyte (O) ratio (P/O) in the prediction of live birth in assisted reproductive technology (ART) cycles. DESIGN: Retrospective cohort study. SETTING: Not applicable. PATIENT(S): A total of 7,608 fresh autologous ART ET cycles. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Live birth. RESULT(S): Generalized estimating equation (GEE) models and receiver operating characteristic curves assessed the ability of P, O, and the P/O ratio to predict live birth...
January 6, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28069175/old-older-and-too-old-age-limits-for-medically-assisted-fatherhood
#8
REVIEW
Andrea Mechanick Braverman
How old is too old to be a father? Can you be a little bit older or "old-ish" to be a dad without being considered an "older dad"? At some point, does one simply become too old to be a father? Unless a man requires medical assistance in family building, that answer has historically turned solely on his opportunity to have a willing female partner of reproductive age. As with so many other aspects of family building, assisted reproductive technologies have transformed the possibilities for-and spawned heated debates about-maternal age...
January 6, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28069173/periconceptional-maternal-biomarkers-of-one-carbon%C3%A2-metabolism-and-embryonic-growth-trajectories-the-rotterdam-periconceptional-cohort-predict-study
#9
Francesca Parisi, Melek Rousian, Anton H J Koning, Sten P Willemsen, Irene Cetin, Eric A P Steegers, Régine P M Steegers-Theunissen
OBJECTIVE: To study the associations between the periconceptional maternal biomarkers of one-carbon metabolism and embryonic growth. DESIGN: Prospective, periconceptional hospital-based birth cohort. SETTING: Tertiary medical care center. PATIENT(S): Between 2010 and 2014, 236 women with early singleton ongoing pregnancies that resulted in 139 strictly dated spontaneous pregnancies and 97 pregnancies conceived after assisted reproductive technology...
January 6, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28069012/systematic-review-of-worldwide-trends-in-assisted-reproductive-technology-2004-2013
#10
REVIEW
Vitaly A Kushnir, David H Barad, David F Albertini, Sarah K Darmon, Norbert Gleicher
BACKGROUND: Assisted Reproductive Technology (ART) has undergone considerable changes over the last decade, with consequences on ART outcomes in different regions of the world being unknown. METHODS: We conducted a systematic review of published national and regional ART registry data to assess how changes in clinical practice between 2004 and 2013 have impacted outcomes in Australia and New Zealand, Canada, Continental Europe, the United Kingdom (U.K.), Japan, Latin America, and the United States (U...
January 10, 2017: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/28068990/risk-factors-for-severe-postpartum-hemorrhage-a-case-control-study
#11
Lill Trine Nyfløt, Irene Sandven, Babill Stray-Pedersen, Silje Pettersen, Iqbal Al-Zirqi, Margit Rosenberg, Anne Flem Jacobsen, Siri Vangen
BACKGROUND: In high-income countries, the incidence of severe postpartum hemorrhage (PPH) has increased. This has important public health relevance because severe PPH is a leading cause of major maternal morbidity. However, few studies have identified risk factors for severe PPH within a contemporary obstetric cohort. METHODS: We performed a case-control study to identify risk factors for severe PPH among a cohort of women who delivered at one of three hospitals in Norway between 2008 and 2011...
January 10, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28059554/searching-for-love-and-test-tube-babies-iraqi-refugee-men-in-reproductive-exile-on-the-margins-of-detroit
#12
Marcia C Inhorn
In this article, I explore the reproductive health problems faced by Iraqi refugees, one of America's most rapidly growing immigrant populations. Based on anthropological research in 'Arab Detroit', the 'capital' of Arab America, I explore the experiences of Iraqi refugee men seeking medical help for their infertility. Most required intracytoplasmic sperm injection (ICSI), a variant of in vitro fertilization (IVF). However, in America's privatized medical system-where a single cycle can cost more than $12,000-few could possibly afford this assisted reproductive technology (ART)...
January 6, 2017: Medical Anthropology
https://www.readbyqxmd.com/read/28056703/does-gnrh-agonist-triggering-control-painful-symptom-scores-during-assisted-reproductive-technology-a-retrospective-study
#13
Mathilde Bourdon, Pietro Santulli, Dominique de Ziegler, Vanessa Gayet, Chloé Maignien, Louis Marcellin, Charles Chapron
OBJECTIVE: The aim of this study was to assess the progression of pain symptoms during assisted reproductive technology (ART) cycles following administration of GnRH agonist (GnRHa) versus human chorionic gonadotrophin (hCG) triggering. DESIGN: Observational cohort study. SETTING: A tertiary care university hospital in France. POPULATION: Patients who underwent ART programs. METHODS: Between January 01, 2014, and June 31, 2014, 122 cycles were allocated to 2 groups: GnRHa triggering with a scheduled differed embryo transfer (n = 57) or hCG triggering with a fresh embryo transfer (n = 70)...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28056241/-research-progress-on-cardiovascular-dysfunction-in-offspring-conceived-by-assisted-reproductive-technology
#14
B J Zhang, S Meng
No abstract text is available yet for this article.
December 24, 2016: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28050959/fertility-preservation-in-endometrial-cancer-is-it-safe-review-of-the-literature
#15
REVIEW
Márcia Mendonça Carneiro, Rívia Mara Lamaita, Márcia Cristina França Ferreira, Agnaldo Lopes Silva-Filho
Almost 5% of women with endometrial cancer are under age 40, and they often have well-differentiated endometrioid estrogen-dependent tumors. Cancer survival rates have improved over the last decades so strategies to avoid or reduce the reproductive damage caused by oncologic treatment are needed. We reviewed the published literature to find evidence to answer the following questions: How should we manage women in reproductive age with endometrial cancer? How safe is fertility preservation in endometrial cancer? Can pregnancy influence endometrial cancer recurrence? What are the fertility sparing options available? Progestins may be prescribed after careful evaluation and counseling...
December 1, 2016: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/28050952/zika-virus-and-assisted-reproductive-technology-to-test-or-not-to-test-that-is-the-question-is-it-an-unnecessary-cost-the-first-two-months-of-mandatory-testing-in-an-outbreak-area-in-rio-de-janeiro-brazil
#16
Maria do Carmo B de Souza, Veronica Raupp, Fernanda Sobrinho, Mariana Menezes, Tatiana R Panaino, Maria A Tamm, Ana C A Mancebo, Ana L R Costa, Roberto A Antunes
OBJECTIVE: Infection by the Zika virus is a Public Health Emergency of International Concern as defined by the World Health Organization. Resolution no. 72, issued by the Collegiate Board of the Brazilian Health Surveillance Agency (ANVISA) on March 30, 2016, made ZKV testing mandatory prior to procedures involving germ cells and tissues. This paper aims to discuss the aforementioned Resolution from the standpoint of evidence and cost-effectiveness of the measures taken within the first two months of mandatory testing...
December 1, 2016: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/28049346/genoproteomics-assisted-improvement-of-andrographis-paniculata-toward-a-promising-molecular-and-conventional-breeding-platform-for-autogamous-plants-affecting-the-pharmaceutical-industry
#17
Alireza Valdiani, Daryush Talei, Surrinder K Lattoo, Rodomiro Ortiz, Søren Kjærsgaard Rasmussen, Jacqueline Batley, Mohd Yusop Rafii, Mahmood Maziah, Kallevettankuzhy K Sabu, Rambod Abiri, Suchirat Sakuanrungsirikul, Soon Guan Tan
Andrographis paniculata (Burm. f.) Wall. ex Nees. (AP) is a hermaphroditic, self-compatible, and habitual inbreeding plant. Its main bioactive component is andrographolide, which is capable of inducing autophagic cell death in some human cancer cells and helps fight HIV/AIDS. Increasing the andrographolide content by investigating the genetic mechanisms controlling its biosynthesis in order to improve and develop high-yielding cultivars are the main breeding targets for AP. However, there might exist some limitations or barriers for crossability within AP accessions...
January 3, 2017: Critical Reviews in Biotechnology
https://www.readbyqxmd.com/read/28029396/standards-of-care-in-infertility-in-europe
#18
REVIEW
Christina I Messini, Alexandros Daponte, George Anifandis, Tahir Mahmood, Ioannis E Messinis
Evidence-based medicine is the principal approach to medical practice. There are several debatable issues in infertility, which require clarification. Over the past 20 years, reliable methodology has been developed for the management of infertile couples. This includes high quality diagnostic and therapeutic procedures, which are applied in highly specialised infertility centres. The European Board and College of Obstetrics and Gynaecology (EBCOG) has published Standards of Care for Women's Health in Europe, which should be the cornerstone for the clinicians and service providers in the European Union to establish common protocols within their centres...
October 20, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28028774/embryo-wastage-rates-remain-high-in-assisted-reproductive-technology-art-a-look-at-the-trends-from-2004-2013-in-the-usa
#19
Sanaz Ghazal, Pasquale Patrizio
This work examined the trend in "embryo wastage" rates after ART in USA and its relationship to the number of embryos transferred, live born infants delivered across patient age, and the yearly percentage of embryos wasted. The data were obtained from the US-clinics SART databank for the years 2004-2013. A total of 1,808,082 non-donor embryos were transferred in 748,394 fresh cycles resulting in 358,214 liveborn. During the years of analysis, the mean number of embryos transferred has progressively decreased leading to an overall significant decrease in Embryo Wastage rates (83...
December 27, 2016: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28018848/mitochondrial-transfer-implications-for-assisted-reproductive-technologies
#20
REVIEW
A S Reznichenko, C Huyser, M S Pepper
The use of mitochondrial transfer as a clinic procedure is drawing closer to reality. Here we provide a detailed overview of mitochondrial transfer techniques - both established and recent - including pronuclear, spindle, ooplasmic and blastomere transfer. Reasons as to why some techniques are more suitable for the prevention of mitochondrial DNA disease than others, as well as the advantages and disadvantages of each methodology, are discussed. The possible clinical introduction of these techniques has raised concerns about the adverse effects they may have on resultant embryos and offspring...
December 2016: Applied & Translational Genomics
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